Development Level

Tbio 38 | 11,651
Tdark 5 | 6,593
Tchem 4 | 1,388
Tclin 1 | 612

IMPC Phenotype

preweaning lethality, complete... 7 | 979
decreased bone mineral content 3 | 151
abnormal behavioral response t... 2 | 66
abnormal bone structure 2 | 187
abnormal lens morphology 2 | 81
cataract 2 | 92
decreased body length 2 | 101
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased circulating alanine ... 2 | 47
decreased circulating choleste... 2 | 93
decreased total body fat amoun... 2 | 207
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
male infertility 2 | 123
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
absent pinna reflex 1 | 23
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased food intake 1 | 13
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
embryonic growth retardation 1 | 106
female infertility 1 | 60
impaired glucose tolerance 1 | 75
increased body temperature 1 | 9
increased circulating HDL chol... 1 | 80
increased circulating chloride... 1 | 41
prenatal lethality 1 | 28
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
shortened RR interval 1 | 17
small kidney 1 | 16
small spleen 1 | 19
small testis 1 | 58
tremors 1 | 39
vertebral transformation 1 | 12

Disease

Carcinoma 34 | 11,493
medulloblastoma, large-cell 27 | 6,241
ovarian cancer 27 | 8,520
osteosarcoma 25 | 7,950
glioblastoma 22 | 5,792
group 3 medulloblastoma 21 | 4,104
psoriasis 21 | 6,694
atypical teratoid / rhabdoid tumor 20 | 5,112
primitive neuroectodermal tumor 20 | 3,035
Breast cancer 19 | 3,578
adult high grade glioma 18 | 3,801
Cancer 17 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
malignant mesothelioma 17 | 3,232
Kidney cancer 16 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
lung cancer 15 | 4,740
ependymoma 14 | 4,679
invasive ductal carcinoma 13 | 2,951
Intellectual disability 12 | 1,016
adrenocortical carcinoma 12 | 1,428
lung adenocarcinoma 11 | 2,716
non-small cell lung cancer 11 | 2,890
Cornelia de Lange syndrome 10 | 21
Roberts syndrome 9 | 15
Atopic dermatitis 8 | 952
Cognitive delay 8 | 608
Fetal Growth Retardation 8 | 189
Global developmental delay 8 | 608
Infant, Small for Gestational Age 8 | 176
Intrauterine retardation 8 | 176
Mental and motor retardation 8 | 608
Short stature 8 | 531
Small head 8 | 374
ductal carcinoma in situ 8 | 1,745
oligodendroglioma 8 | 2,850
Alzheimer's disease 7 | 658
Astrocytoma, Pilocytic 7 | 3,081
Dull intelligence 7 | 645
Hypoplastic mandible condyle 7 | 275
Low intelligence 7 | 645
Mandibular hypoplasia 7 | 275
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Micrognathism 7 | 275
Poor school performance 7 | 645
Rheumatoid arthritis 7 | 1,191
astrocytic glioma 7 | 2,597
breast carcinoma 7 | 1,638
diabetes mellitus 7 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
Bilateral fifth finger clinodactyly 6 | 110
Blepharoptosis 6 | 231
Cryptorchidism 6 | 296
Curvature of little finger 6 | 110
Delayed bone age 6 | 136
Downturned corners of mouth 6 | 48
Failure to gain weight 6 | 365
Infertility 6 | 188
KBG syndrome 6 | 9
Pediatric failure to thrive 6 | 365
Pick disease 6 | 1,894
group 4 medulloblastoma 6 | 1,855
pancreatic cancer 6 | 2,398
Anteverted nostril 5 | 191
Attention deficit hyperactivity disorder 5 | 278
Bladder Neoplasm 5 | 112
Byzanthine arch palate 5 | 194
Cutis marmorata 5 | 32
Endometriosis 5 | 540
Feeding difficulties in infancy 5 | 175
Late tooth eruption 5 | 61
Long philtrum 5 | 137
Multiple myeloma 5 | 1,332
Obesity 5 | 678
Penile hypospadias 5 | 106
Sensorineural Hearing Loss (disorder) 5 | 284
Severe postnatal growth retardation 5 | 16
Short nose 5 | 132
Small nose 5 | 132
Thin lips 5 | 49
Urinary Bladder Neoplasms 5 | 114
Waldenstrons macroglobulinemia 5 | 765
colon cancer 5 | 1,478
juvenile dermatomyositis 5 | 1,187
nasopharyngeal carcinoma 5 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
primary Sjogren syndrome 5 | 735
Bilateral single transverse palmar creases 4 | 34
Bipolar Disorder 4 | 666
Depressed nasal bridge 4 | 195
Depressed nasal root/bridge 4 | 195
Male infertility 4 | 206
Micromelia 4 | 58
Syndactyly of the toes 4 | 45
acute quadriplegic myopathy 4 | 1,158
astrocytoma 4 | 1,146
pediatric high grade glioma 4 | 1,064
pituitary cancer 4 | 1,972
progressive supranuclear palsy 4 | 676

Tissue

Endocrine System 46 | 18,159
Blood and immune system 44 | 16,909
Female tissues 44 | 17,400
Skin and soft tissues 44 | 17,230
Digestive Tract 43 | 17,369
Male tissues 43 | 17,142
Liver and Pancreas 42 | 16,750
Respiratory system 42 | 16,393
Urinary Tract 42 | 16,678
Nervous System 41 | 16,725
Cardiovascular System 39 | 15,192

Target Family

Non-IDG 32 | 12,091
Enzyme 9 | 4,145
Kinase 4 | 634
Transcription Factor 2 | 1,400
Epigenetic 1 | 242

Compartment GO Term

Cohesin complex 48 | 48
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Securin PTTG1 Tbio Non-IDG -2.42127 261.4 311
Chromosome transmission fidelity protein 18 homolog CHTF18 Tbio Non-IDG -1.51235 35.5 138
Mitotic checkpoint serine/threonine-protein kinase BUB1 BUB1 Tchem Kinase -2.31533 200.0 373
MAU2 chromatid cohesion factor homolog MAU2 Tdark Non-IDG -2.03797 96.6 32
Nipped-B-like protein NIPBL Tbio Non-IDG -2.25874 186.3 134
Serine/threonine-protein kinase PLK1 PLK1 Tchem Kinase -3.09610 1271.1 856
Insulin INS Tbio Non-IDG -5.17849 146933.7 2197
Synaptonemal complex protein 3 SYCP3 Tbio Non-IDG -2.20845 154.4 255
Insulin-like growth factor II IGF2 Tbio Non-IDG -3.65750 4465.3 457
Shugoshin 2 SGO2 Tbio Non-IDG -1.31971 22.3 90