Development Level

Tbio 205 | 11,651
Tchem 13 | 1,388
Tdark 12 | 6,593
Tclin 10 | 612

Collection

Kinase: IDG Consortium (Target... 2 | 125
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, complete... 12 | 979
embryonic lethality prior to t... 6 | 278
abnormal lens morphology 5 | 81
decreased total body fat amoun... 5 | 207
decreased vertical activity 5 | 208
preweaning lethality, incomple... 5 | 499
cataract 4 | 92
embryonic lethality prior to o... 4 | 239
hyperactivity 4 | 148
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
abnormal heart morphology 3 | 162
decreased circulating LDL chol... 3 | 38
decreased circulating choleste... 3 | 93
decreased fasted circulating g... 3 | 65
embryonic growth retardation 3 | 106
enlarged heart 3 | 210
hydrometra 3 | 53
increased circulating free fat... 3 | 20
increased circulating sodium l... 3 | 71
increased total body fat amoun... 3 | 134
small superior vagus ganglion 3 | 74
abnormal bone structure 2 | 187
abnormal kidney morphology 2 | 65
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
abnormal sleep behavior 2 | 70
abnormal testis morphology 2 | 43
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 68
decreased circulating free fat... 2 | 31
decreased circulating serum al... 2 | 82
decreased circulating triglyce... 2 | 79
decreased grip strength 2 | 116
enlarged seminal vesicle 2 | 10
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased circulating potassiu... 2 | 29
increased erythrocyte cell num... 2 | 39
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
small testis 2 | 58
thrombocytosis 2 | 27
abnormal allantois morphology 1 | 8
abnormal blood vessel morpholo... 1 | 5
abnormal chorioallantoic fusio... 1 | 8
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal left-right axis patte... 1 | 2
abnormal liver morphology 1 | 17
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal pericardium morpholog... 1 | 26
abnormal pharyngeal arch morph... 1 | 8
abnormal retinal blood vessel ... 1 | 26
abnormal somite shape 1 | 5
abnormal tail bud morphology 1 | 8
abnormal tooth morphology 1 | 24
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
abnormal whole-body plethysmog... 1 | 4
absent pinna reflex 1 | 23
cardiovascular system phenotyp... 1 | 36
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating insulin ... 1 | 76
decreased circulating sodium l... 1 | 22
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased heart left ventricle... 1 | 28
decreased heart rate variabili... 1 | 13
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating iron lev... 1 | 30
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased heart rate 1 | 23
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased prepulse inhibition 1 | 32
increased vertical activity 1 | 24
limb grasping 1 | 41
microphthalmia 1 | 26
thin ventricular wall 1 | 24
tremors 1 | 39

Disease

Carcinoma 136 | 11,493
psoriasis 127 | 6,694
ovarian cancer 105 | 8,520
Cancer 104 | 2,499
diabetes mellitus 96 | 1,728
osteosarcoma 81 | 7,950
glioblastoma 73 | 5,792
Ankylosing spondylitis 71 | 140
Behcet's disease 70 | 89
Hypersensitivity reaction type II disease 66 | 253
Rheumatoid arthritis 63 | 1,191
medulloblastoma, large-cell 63 | 6,241
Juvenile rheumatoid arthritis 61 | 111
Arthritis 60 | 290
Acquired immunodeficiency syndrome 58 | 197
Uveitis 57 | 103
Herpes zoster 56 | 68
Human immunodeficiency virus infectious disease 53 | 138
Psoriatic arthritis 52 | 86
dermatomyositis 52 | 966
atypical teratoid / rhabdoid tumor 51 | 5,112
ependymoma 51 | 4,679
lung cancer 51 | 4,740
Stevens-Johnson syndrome 50 | 92
Astrocytoma, Pilocytic 46 | 3,081
tuberculosis 44 | 2,010
lung carcinoma 41 | 2,843
malignant mesothelioma 40 | 3,232
Breast cancer 39 | 3,578
adult high grade glioma 39 | 3,801
Dermatitis 38 | 157
intraductal papillary-mucinous adenoma (IPMA) 38 | 2,955
Congenital adrenal hyperplasia 36 | 73
invasive ductal carcinoma 36 | 2,951
lung adenocarcinoma 36 | 2,716
Behcet's syndrome 35 | 50
Multiple Sclerosis 35 | 540
Nephritis 35 | 51
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
Synovitis 35 | 78
Takayasu's arteritis 35 | 53
drug-induced hepatitis 35 | 44
non-small cell lung cancer 34 | 2,890
Kidney disease 33 | 430
Multiple myeloma 33 | 1,332
astrocytic glioma 32 | 2,597
subependymal giant cell astrocytoma 32 | 2,287
Liver disease 31 | 237
group 3 medulloblastoma 30 | 4,104
Anemia 29 | 365
Hepatitis B 29 | 108
pancreatic cancer 29 | 2,398
interstitial cystitis 28 | 2,312
Autosomal recessive predisposition 27 | 1,442
Kidney cancer 27 | 2,613
oligodendroglioma 27 | 2,850
Pick disease 26 | 1,894
intraductal papillary-mucinous carcinoma (IPMC) 26 | 2,989
Hemochromatosis 25 | 54
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,291
primitive neuroectodermal tumor 25 | 3,035
Leprosy 24 | 73
Schizophrenia 24 | 1,160
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,962
pituitary cancer 24 | 1,972
breast carcinoma 23 | 1,638
cutaneous lupus erythematosus 23 | 1,057
juvenile dermatomyositis 22 | 1,187
Birdshot chorioretinopathy 21 | 23
Primary immunodeficiency disease 21 | 54
Skin disease 21 | 66
acute quadriplegic myopathy 20 | 1,158
Bipolar Disorder 19 | 666
group 4 medulloblastoma 19 | 1,855
astrocytoma 18 | 1,146
cystic fibrosis 18 | 1,696
ductal carcinoma in situ 17 | 1,745
esophageal adenocarcinoma 17 | 737
pediatric high grade glioma 17 | 1,064
adrenocortical carcinoma 16 | 1,428
Pre-Eclampsia 15 | 68
Alzheimer's disease 14 | 658
Down syndrome 14 | 499
Duchenne muscular dystrophy 14 | 601
Human immunodeficiency virus type 1, susceptibility to 14 | 26
Psoriasis susceptibility 1 14 | 14
active Crohn's disease 14 | 922
spina bifida 14 | 1,074
Cataract 8 multiple types 13 | 33
Epilepsy 13 | 792
Liver cancer 13 | 604
ulcerative colitis 13 | 1,819
Alcoholic Intoxication, Chronic 12 | 289
Major Depressive Disorder 12 | 301
Obesity 11 | 678
Prostatic Neoplasms 11 | 495
gastric carcinoma 11 | 807
pancreatic carcinoma 11 | 562
primary pancreatic ductal adenocarcinoma 11 | 1,109

Tissue

Skin and soft tissues 167 | 17,230
Digestive Tract 166 | 17,369
Endocrine System 165 | 18,159
Female tissues 165 | 17,400
Liver and Pancreas 162 | 16,750
Blood and immune system 161 | 16,909
Male tissues 161 | 17,142
Respiratory system 161 | 16,393
Urinary Tract 160 | 16,678
Nervous System 159 | 16,725
Cardiovascular System 152 | 15,192

Target Family

Non-IDG 199 | 12,091
Enzyme 18 | 4,145
Transporter 8 | 473
GPCR 6 | 408
Kinase 4 | 634
Transcription Factor 3 | 1,400
Ion Channel 2 | 344

Compartment GO Term

Coated vesicle membrane 240 | 240
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTP-binding protein SAR1b SAR1B Tbio Enzyme -1.91051 79.7 184
HLA class I histocompatibility antigen, A-25 alpha chain HLA-A Tbio Non-IDG -2.41667 4123.8 0
HLA class I histocompatibility antigen, B-51 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
ADP-ribosylation factor GTPase-activating protein 2 ARFGAP2 Tbio Enzyme -0.97596 10.1 144
Coatomer subunit beta COPB1 Tbio Non-IDG -1.94049 82.6 148
Coatomer subunit alpha COPA Tbio Non-IDG -2.45140 283.3 88
Drebrin-like protein DBNL Tbio Non-IDG -1.16567 21.1 172
HLA class I histocompatibility antigen, B-37 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
Vesicle-associated membrane protein 8 VAMP8 Tbio Non-IDG -1.79654 64.6 107
AP-1 complex subunit mu-2 AP1M2 Tbio Non-IDG -2.54240 341.5 68