Development Level

Tbio 246 | 10,625
Tchem 34 | 1,890
Tdark 21 | 7,003
Tclin 4 | 602

Collection

Eligible Kinase Proteins 2 | 134

IMPC Term

preweaning lethality, complete... 12 | 633
abnormal behavior 8 | 226
embryonic lethality prior to t... 7 | 187
increased or absent threshold ... 6 | 128
decreased circulating HDL chol... 5 | 77
decreased total body fat amoun... 5 | 186
abnormal lens morphology 4 | 73
decreased body length 4 | 108
decreased circulating LDL chol... 4 | 37
decreased circulating choleste... 4 | 85
decreased grip strength 4 | 123
abnormal bone structure 3 | 131
decreased body weight 3 | 174
decreased bone mineral content 3 | 157
decreased bone mineral density 3 | 126
decreased lean body mass 3 | 195
embryonic lethality prior to o... 3 | 148
hyperactivity 3 | 108
increased circulating alkaline... 3 | 119
increased mean corpuscular hem... 3 | 93
preweaning lethality, incomple... 3 | 260
abnormal embryo size 2 | 112
abnormal hindbrain development 2 | 24
abnormal midbrain development 2 | 22
abnormal neural tube closure 2 | 37
abnormal sleep behavior 2 | 63
abnormal testis morphology 2 | 30
cataract 2 | 26
decreased circulating free fat... 2 | 39
decreased fasted circulating g... 2 | 49
decreased gamma-delta T cell n... 2 | 18
decreased mean corpuscular hem... 2 | 34
decreased prepulse inhibition 2 | 52
hypoactivity 2 | 89
increased circulating HDL chol... 2 | 63
increased circulating LDL chol... 2 | 15
increased circulating chloride... 2 | 43
increased circulating free fat... 2 | 17
increased circulating sodium l... 2 | 71
increased total body fat amoun... 2 | 57
male infertility 2 | 62
abnormal QRS complex 1 | 25
abnormal epididymis morphology 1 | 31
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal forebrain development 1 | 18
abnormal gait 1 | 51
abnormal heart morphology 1 | 51
abnormal kidney morphology 1 | 30
abnormal retina morphology 1 | 100
abnormal retinal blood vessel ... 1 | 18
abnormal retinal pigmentation 1 | 61
abnormal spinal cord morpholog... 1 | 8
abnormal vibrissa morphology 1 | 17
absent heartbeat 1 | 6
absent pinna reflex 1 | 21
absent vibrissae 1 | 14
cardiovascular system phenotyp... 1 | 35
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased alpha-beta T cell nu... 1 | 12
decreased caudal vertebrae num... 1 | 49
decreased circulating calcium ... 1 | 33
decreased circulating serum al... 1 | 79
decreased effector memory CD4-... 1 | 6
decreased heart rate variabili... 1 | 11
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased monocyte cell number 1 | 28
decreased vertical activity 1 | 22
enlarged heart atrium 1 | 2
enlarged lymph nodes 1 | 27
female infertility 1 | 34
hydrops fetalis 1 | 22
impaired pupillary reflex 1 | 14
increased B cell number 1 | 23
increased CD4-positive, CD25-p... 1 | 18
increased T cell number 1 | 15
increased blood urea nitrogen ... 1 | 44
increased body length 1 | 20
increased body weight 1 | 42
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased erythrocyte cell num... 1 | 26
increased mature B cell number 1 | 12
increased mean corpuscular vol... 1 | 91
increased prepulse inhibition 1 | 21
increased rib number 1 | 41
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
increased thoracic vertebrae n... 1 | 8
increased vertical activity 1 | 18
limb grasping 1 | 35
microphthalmia 1 | 15
mydriasis 1 | 9
short tibia 1 | 82
small testis 1 | 37
thrombocytosis 1 | 23

Disease

ovarian cancer 153 | 8,492
psoriasis 153 | 6,685
Cancer 117 | 2,346
osteosarcoma 116 | 7,933
diabetes mellitus 108 | 1,663
glioblastoma 101 | 5,572
medulloblastoma, large-cell 93 | 6,234
Hypersensitivity reaction type II disease 73 | 235
atypical teratoid / rhabdoid tumor 73 | 4,369
lung cancer 72 | 4,473
Ankylosing spondylitis 71 | 138
Rheumatoid Arthritis 68 | 1,171
Arthritis 64 | 248
dermatomyositis 64 | 967
Juvenile rheumatoid arthritis 62 | 105
Acquired immunodeficiency syndrome 59 | 164
Uveitis 59 | 103
pilocytic astrocytoma 58 | 3,086
Behcet's disease 57 | 74
lung carcinoma 57 | 2,844
intraductal papillary-mucinous adenoma (IPMA) 54 | 2,956
Human immunodeficiency virus infectious disease 52 | 129
Psoriatic arthritis 52 | 85
Stevens-Johnson syndrome 50 | 91
invasive ductal carcinoma 48 | 2,950
lung adenocarcinoma 47 | 2,714
pediatric high grade glioma 47 | 2,712
Breast cancer 46 | 3,099
oligodendroglioma 46 | 2,849
astrocytoma 43 | 1,493
malignant mesothelioma 43 | 3,163
pancreatic cancer 43 | 2,300
Multiple myeloma 42 | 1,328
intraductal papillary-mucinous carcinoma (IPMC) 42 | 2,988
non-small cell lung cancer 42 | 2,798
primitive neuroectodermal tumor 42 | 3,031
intraductal papillary-mucinous neoplasm (IPMN) 41 | 3,289
interstitial cystitis 39 | 2,299
subependymal giant cell astrocytoma 39 | 2,287
Dermatitis 38 | 141
ependymoma 38 | 2,514
Pick disease 37 | 1,893
Liver disease 36 | 219
Retinal vasculitis 36 | 36
Behcet's syndrome 35 | 50
Congenital adrenal hyperplasia 35 | 74
Nephritis 35 | 63
Spondyloarthropathy, Susceptibility To, 1 35 | 35
Synovitis 35 | 72
Takayasu's arteritis 35 | 54
drug-induced hepatitis 35 | 44
Carcinoma 34 | 2,147
Kidney disease 34 | 397
Multiple Sclerosis 34 | 498
pancreatic ductal adenocarcinoma liver metastasis 33 | 1,795
Anemia 31 | 252
astrocytic glioma 31 | 2,241
posterior fossa group A ependymoma 31 | 1,511
pituitary cancer 30 | 1,972
tuberculosis 30 | 1,563
breast carcinoma 29 | 1,614
adult high grade glioma 28 | 2,148
cutaneous lupus erythematosus 28 | 1,056
group 4 medulloblastoma 28 | 1,875
Hepatitis B 26 | 103
Hemochromatosis 25 | 55
Leprosy 25 | 77
juvenile dermatomyositis 25 | 1,189
acute quadriplegic myopathy 24 | 1,157
cystic fibrosis 24 | 1,670
medulloblastoma 24 | 1,524
ulcerative colitis 23 | 2,087
Skin disease 22 | 65
ductal carcinoma in situ 22 | 1,745
Birdshot chorioretinopathy 21 | 23
Primary immunodeficiency disease 21 | 52
primary pancreatic ductal adenocarcinoma 21 | 1,271
sonic hedgehog group medulloblastoma 21 | 1,482
esophageal adenocarcinoma 20 | 737
posterior fossa group B ependymoma 20 | 1,530
Alzheimer's disease 19 | 644
group 3 medulloblastoma 19 | 2,254
active Crohn's disease 18 | 918
Down syndrome 16 | 548
adrenocortical carcinoma 16 | 1,427
pancreatic carcinoma 16 | 567
pre-eclampsia 15 | 67
spina bifida 15 | 1,064
Duchenne muscular dystrophy 14 | 602
Human immunodeficiency virus type 1, susceptibility to 14 | 26
Psoriasis susceptibility 1 14 | 14
Waldenstrons macroglobulinemia 14 | 765
gastric carcinoma 14 | 832
mucosa-associated lymphoid tissue lymphoma 14 | 480
atypical teratoid/rhabdoid tumor 13 | 1,095
non primary Sjogren syndrome sicca 13 | 840
primary Sjogren syndrome 13 | 789
Asthma 12 | 349
acute myeloid leukemia 12 | 785
colon cancer 12 | 1,475

Tissue

Endocrine System 242 | 18,512
Blood and immune system 241 | 17,995
Cardiovascular System 241 | 17,958
Digestive Tract 241 | 18,473
Female tissues 241 | 18,647
Liver and Pancreas 241 | 18,136
Nervous System 241 | 18,561
Male tissues 240 | 17,969
Urinary Tract 240 | 18,444
Respiratory system 239 | 17,484
Skin and soft tissues 233 | 18,115

Target Family

Non-IDG 249 | 11,969
Enzyme 32 | 4,146
Transporter 10 | 473
Kinase 7 | 634
GPCR 3 | 408
Transcription Factor 3 | 1,400
Ion Channel 1 | 341

Compartment GO Term

Coated vesicle 305 | 305
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, alpha chain G HLA-G Tbio Non-IDG -3.07995 1275.9 729
Protein unc-13 homolog D UNC13D Tbio Non-IDG -1.89144 80.2 134
Transmembrane emp24 domain-containing protein 3 TMED3 Tbio Non-IDG -0.85200 7.21 86
Protein YIF1B YIF1B Tbio Non-IDG -0.80844 5.59 61
5,6-dihydroxyindole-2-carboxylic acid oxidase TYRP1 Tchem Enzyme -2.93891 844.0 215
HLA class II histocompatibility antigen, DP beta 1 chain HLA-DPB1 Tbio Non-IDG -2.67719 572.7 274
HLA class I histocompatibility antigen, A-3 alpha chain HLA-A Tbio Non-IDG -2.40709 4042.7 585
Potassium-transporting ATPase alpha chain 2 ATP12A Tchem Transporter -3.80030 5982.8 71
Cell migration-inducing and hyaluronan-binding protein CEMIP Tbio Non-IDG -1.48609 34.0 98
Phosphatidylinositol-binding clathrin assembly protein PICALM Tbio Non-IDG -1.91723 81.1 124