Development Level

Tbio 110 | 11,651
Tchem 23 | 1,388
Tclin 16 | 612
Tdark 7 | 6,593

IMPC Phenotype

increased circulating sodium l... 6 | 71
preweaning lethality, complete... 6 | 979
preweaning lethality, incomple... 5 | 499
absent pinna reflex 4 | 23
decreased body weight 4 | 161
increased circulating HDL chol... 4 | 80
increased or absent threshold ... 4 | 101
abnormal behavior 3 | 298
decreased circulating amylase ... 3 | 28
decreased circulating triglyce... 3 | 79
decreased leukocyte cell numbe... 3 | 73
increased circulating alkaline... 3 | 122
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal lens morphology 2 | 81
absent startle reflex 2 | 24
cataract 2 | 92
decreased body length 2 | 101
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased grip strength 2 | 116
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
impaired glucose tolerance 2 | 75
impaired righting response 2 | 26
improved glucose tolerance 2 | 79
increased blood urea nitrogen ... 2 | 48
increased circulating chloride... 2 | 41
increased circulating choleste... 2 | 66
increased circulating total pr... 2 | 28
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
increased thermal nociceptive ... 2 | 9
increased total body fat amoun... 2 | 134
increased vertical activity 2 | 24
limb grasping 2 | 41
polycystic kidney 2 | 15
prolonged ST segment 2 | 36
stereotypic behavior 2 | 3
tremors 2 | 39
trunk curl 2 | 16
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal coat appearance 1 | 31
abnormal ear morphology 1 | 9
abnormal heart morphology 1 | 162
abnormal iris morphology 1 | 13
abnormal kidney morphology 1 | 65
abnormal locomotor activation 1 | 16
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal spine curvature 1 | 9
abnormal spleen morphology 1 | 55
abnormal urinary bladder morph... 1 | 11
abnormal vibrissa morphology 1 | 25
abnormal vocalization 1 | 21
abnormal whole-body plethysmog... 1 | 4
cardiovascular system phenotyp... 1 | 36
convulsive seizures 1 | 13
cystolithiasis 1 | 3
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating potassiu... 1 | 20
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
enlarged kidney 1 | 14
enlarged spleen 1 | 41
enlarged urinary bladder 1 | 8
eyelids fail to open 1 | 3
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
increased anti-nuclear antigen... 1 | 19
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating serum al... 1 | 22
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
kyphosis 1 | 5
persistence of hyaloid vascula... 1 | 33
prolonged PR interval 1 | 15
prolonged QT interval 1 | 38
small kidney 1 | 16
small superior vagus ganglion 1 | 74

Disease

Carcinoma 120 | 11,493
psoriasis 64 | 6,694
osteosarcoma 63 | 7,950
ovarian cancer 56 | 8,520
Autosomal recessive predisposition 46 | 1,442
lung cancer 42 | 4,740
intraductal papillary-mucinous carcinoma (IPMC) 40 | 2,989
glioblastoma 37 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 37 | 2,955
medulloblastoma, large-cell 37 | 6,241
Kidney cancer 35 | 2,613
diabetes mellitus 34 | 1,728
malignant mesothelioma 33 | 3,232
Nonsyndromic deafness 32 | 142
ependymoma 32 | 4,679
Breast cancer 31 | 3,578
Cancer 31 | 2,499
lung adenocarcinoma 31 | 2,716
lung carcinoma 29 | 2,843
ulcerative colitis 29 | 1,819
atypical teratoid / rhabdoid tumor 28 | 5,112
pancreatic cancer 28 | 2,398
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,291
non-small cell lung cancer 27 | 2,890
Kidney disease 25 | 430
Hypertension 24 | 396
adult high grade glioma 24 | 3,801
pituitary cancer 24 | 1,972
cystic fibrosis 23 | 1,696
invasive ductal carcinoma 23 | 2,951
Astrocytoma, Pilocytic 22 | 3,081
Obesity 22 | 678
Diarrhea 21 | 253
Schizophrenia 21 | 1,160
tuberculosis 21 | 2,010
group 3 medulloblastoma 20 | 4,104
Anemia 19 | 365
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,962
Liver cancer 18 | 604
interstitial cystitis 18 | 2,312
nephrosclerosis 18 | 333
oligodendroglioma 18 | 2,850
astrocytic glioma 17 | 2,597
colon cancer 17 | 1,478
primitive neuroectodermal tumor 17 | 3,035
subependymal giant cell astrocytoma 17 | 2,287
Sensorineural hearing loss 16 | 106
ductal carcinoma in situ 16 | 1,745
pediatric high grade glioma 16 | 1,064
Metabolic acidosis 15 | 90
active Crohn's disease 15 | 922
breast carcinoma 15 | 1,638
Melanoma 14 | 711
Atherosclerosis 13 | 291
Heart disease 13 | 306
Sensorineural Hearing Loss (disorder) 13 | 284
group 4 medulloblastoma 13 | 1,855
Alzheimer's disease 12 | 658
Coronary artery disease 12 | 268
Epilepsy 12 | 792
Intellectual disability 12 | 1,016
Liver Cirrhosis, Experimental 12 | 769
Liver disease 12 | 237
Rheumatoid arthritis 12 | 1,191
Skin cancer 12 | 469
Cognitive delay 11 | 608
Failure to gain weight 11 | 365
Global developmental delay 11 | 608
Mental and motor retardation 11 | 608
Osteoporosis 11 | 363
Pediatric failure to thrive 11 | 365
Pick disease 11 | 1,894
Cataract 10 | 297
Cholestasis 10 | 155
Dull intelligence 10 | 645
Hyperglycemia 10 | 137
Hypertensive disease 10 | 292
Low intelligence 10 | 645
Mental Retardation 10 | 645
Mental deficiency 10 | 645
Poor school performance 10 | 645
Retinitis Pigmentosa 10 | 226
Usher syndrome 10 | 32
acute quadriplegic myopathy 10 | 1,158
adrenocortical carcinoma 10 | 1,428
astrocytoma 10 | 1,146
esophageal adenocarcinoma 10 | 737
gastric carcinoma 10 | 807
Bipolar Disorder 9 | 666
Cerebrovascular disease 9 | 238
Fatty liver disease 9 | 103
Heart failure 9 | 162
Hepatomegaly 9 | 285
Hyperuricemia 9 | 47
Hypoglycemia 9 | 152
Hypophosphatemia 9 | 40
Lens Opacities 9 | 231
Nephrolithiasis 9 | 56
Prostatic Neoplasms 9 | 495
primary pancreatic ductal adenocarcinoma 9 | 1,109

Tissue

Digestive Tract 147 | 17,369
Endocrine System 143 | 18,159
Skin and soft tissues 143 | 17,230
Male tissues 141 | 17,142
Urinary Tract 140 | 16,678
Liver and Pancreas 139 | 16,750
Female tissues 138 | 17,400
Nervous System 134 | 16,725
Blood and immune system 132 | 16,909
Respiratory system 125 | 16,393
Cardiovascular System 106 | 15,192

Target Family

Non-IDG 76 | 12,091
Transporter 38 | 473
Enzyme 36 | 4,145
Ion Channel 4 | 344
Kinase 2 | 634

Compartment GO Term

Cluster of actin-based cell pr... 156 | 156
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alkaline phosphatase, placental type ALPP Tbio Enzyme -2.71952 511.2 929
Unconventional myosin-VIIb MYO7B Tbio Non-IDG -0.65885 5.07 14
Intelectin-1 ITLN1 Tbio Non-IDG -2.49500 337.0 194
Gastric intrinsic factor GIF Tbio Non-IDG -3.20615 1559.4 172
KICSTOR complex protein kaptin KPTN Tbio Non-IDG -1.45875 26.8 153
Platelet glycoprotein 4 CD36 Tbio Non-IDG -2.63884 376.0 1155
Ezrin EZR Tbio Non-IDG -2.99865 981.3 1088
Unconventional myosin-Vb MYO5B Tbio Non-IDG -1.96052 93.4 42
Unconventional myosin-Id MYO1D Tbio Non-IDG -1.39704 23.1 63
Trehalase TREH Tchem Enzyme -2.14508 137.4 51