Development Level

Tbio 95 | 10,625
Tchem 30 | 1,890
Tclin 12 | 602
Tdark 4 | 7,003

IMPC Term

decreased total body fat amoun... 5 | 186
increased circulating sodium l... 5 | 71
absent pinna reflex 4 | 21
decreased body length 4 | 108
decreased grip strength 4 | 123
increased circulating alkaline... 4 | 119
increased or absent threshold ... 4 | 128
preweaning lethality, complete... 4 | 633
abnormal behavior 3 | 226
absent startle reflex 3 | 15
decreased circulating HDL chol... 3 | 77
decreased circulating amylase ... 3 | 24
decreased circulating choleste... 3 | 85
decreased circulating glucose ... 3 | 121
decreased circulating triglyce... 3 | 83
decreased lean body mass 3 | 195
decreased prepulse inhibition 3 | 52
decreased startle reflex 3 | 48
increased circulating chloride... 3 | 43
abnormal bone structure 2 | 131
abnormal lens morphology 2 | 73
abnormal retina morphology 2 | 100
abnormal vibrissa morphology 2 | 17
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
decreased circulating free fat... 2 | 39
decreased circulating insulin ... 2 | 75
impaired glucose tolerance 2 | 52
impaired righting response 2 | 19
increased blood urea nitrogen ... 2 | 44
increased circulating total pr... 2 | 20
increased grip strength 2 | 83
increased mean corpuscular hem... 2 | 93
limb grasping 2 | 35
stereotypic behavior 2 | 3
trunk curl 2 | 15
abnormal behavioral response t... 1 | 52
abnormal bone mineralization 1 | 55
abnormal coat appearance 1 | 25
abnormal digestive system phys... 1 | 1
abnormal ear morphology 1 | 5
abnormal epididymis morphology 1 | 31
abnormal eye morphology 1 | 38
abnormal glucose homeostasis 1 | 5
abnormal heart left ventricle ... 1 | 20
abnormal incisor color 1 | 2
abnormal iris morphology 1 | 12
abnormal locomotor activation 1 | 26
abnormal motor coordination/ b... 1 | 4
abnormal posture 1 | 5
abnormal respiratory quotient 1 | 9
abnormal retinal pigmentation 1 | 61
abnormal skin morphology 1 | 23
abnormal spine curvature 1 | 7
cardiovascular system phenotyp... 1 | 35
cataract 1 | 26
decreased NK T cell number 1 | 28
decreased bone mineral density 1 | 126
decreased circulating alanine ... 1 | 53
decreased circulating calcium ... 1 | 33
decreased circulating glycerol... 1 | 19
decreased circulating potassiu... 1 | 17
decreased fasted circulating g... 1 | 49
decreased heart weight 1 | 44
decreased leukocyte cell numbe... 1 | 54
decreased monocyte cell number 1 | 28
decreased neutrophil cell numb... 1 | 37
enlarged epididymis 1 | 27
eyelids fail to open 1 | 2
hyperactivity 1 | 108
hypoactivity 1 | 89
improved glucose tolerance 1 | 56
increased B cell number 1 | 23
increased NK T cell number 1 | 11
increased body weight 1 | 42
increased bone mineral content 1 | 92
increased circulating HDL chol... 1 | 63
increased circulating amylase ... 1 | 13
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating magnesiu... 1 | 10
increased circulating serum al... 1 | 25
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased mean platelet volume 1 | 19
increased plasma cell number 1 | 5
increased rib number 1 | 41
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 57
increased vertical activity 1 | 18
kyphosis 1 | 5
persistence of hyaloid vascula... 1 | 22
polycystic kidney 1 | 9
preweaning lethality, incomple... 1 | 260
sclerocornea 1 | 2
straub tail 1 | 26

Disease

psoriasis 60 | 6,685
osteosarcoma 54 | 7,933
ovarian cancer 51 | 8,484
intraductal papillary-mucinous carcinoma (IPMC) 37 | 2,988
lung cancer 36 | 4,466
medulloblastoma, large-cell 36 | 6,234
intraductal papillary-mucinous adenoma (IPMA) 35 | 2,956
glioblastoma 34 | 5,572
Carcinoma 32 | 2,147
diabetes mellitus 31 | 1,663
ulcerative colitis 31 | 2,087
lung carcinoma 30 | 2,844
Nonsyndromic deafness 29 | 121
lung adenocarcinoma 29 | 2,713
malignant mesothelioma 28 | 3,162
Cancer 26 | 2,346
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,289
Kidney disease 24 | 396
cystic fibrosis 24 | 1,665
non-small cell lung cancer 24 | 2,798
pancreatic cancer 23 | 2,300
pediatric high grade glioma 22 | 2,712
pituitary cancer 22 | 1,972
invasive ductal carcinoma 21 | 2,950
Breast cancer 20 | 3,094
Diarrhea 20 | 155
Obesity 20 | 616
atypical teratoid / rhabdoid tumor 20 | 4,369
Anemia 19 | 252
pilocytic astrocytoma 19 | 3,086
Hypertension 18 | 287
Sensorineural hearing loss 18 | 107
interstitial cystitis 18 | 2,299
tuberculosis 18 | 1,557
nephrosclerosis 17 | 329
oligodendroglioma 17 | 2,849
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,795
adult high grade glioma 16 | 2,148
colon cancer 16 | 1,475
ductal carcinoma in situ 16 | 1,745
ependymoma 16 | 2,514
primitive neuroectodermal tumor 16 | 3,031
active Crohn's disease 15 | 918
subependymal giant cell astrocytoma 15 | 2,287
Atherosclerosis 14 | 275
astrocytic glioma 14 | 2,241
breast carcinoma 13 | 1,614
group 4 medulloblastoma 13 | 1,875
Liver disease 12 | 219
Rheumatoid Arthritis 12 | 1,160
Usher syndrome 12 | 34
astrocytoma 12 | 1,493
posterior fossa group B ependymoma 12 | 1,530
sonic hedgehog group medulloblastoma 12 | 1,482
Coronary artery disease 11 | 240
Heart disease 11 | 279
Hyperglycemia 11 | 120
Metabolic acidosis 11 | 49
Metabolic syndrome X 11 | 155
Pick disease 11 | 1,893
Alzheimer's disease 10 | 644
Hypoglycemia 10 | 81
Retinitis pigmentosa 10 | 153
acute quadriplegic myopathy 10 | 1,157
atypical teratoid/rhabdoid tumor 10 | 1,095
primary pancreatic ductal adenocarcinoma 10 | 1,271
Hypertensive disease 9 | 193
Prostatic Neoplasms 9 | 471
adrenocortical carcinoma 9 | 1,427
gastric carcinoma 9 | 832
Alcohol dependence 8 | 107
Blindness 8 | 84
Cerebrovascular disease 8 | 231
Fatty liver disease 8 | 84
Hodgkin's lymphoma, nodular sclerosis 8 | 24
Hyperphosphatemia 8 | 32
Hypophosphatemia 8 | 31
Osteoporosis 8 | 257
chronic rhinosinusitis 8 | 512
cutaneous lupus erythematosus 8 | 1,056
esophageal adenocarcinoma 8 | 737
facioscapulohumeral dystrophy 8 | 286
group 3 medulloblastoma 8 | 2,254
juvenile dermatomyositis 8 | 1,189
posterior fossa group A ependymoma 8 | 1,511
sarcoidosis 8 | 358
Calcinosis 7 | 62
Cholestasis 7 | 93
Diabetes mellitus type 2 7 | 69
Hyperparathyroidism 7 | 43
Hypersensitivity reaction type II disease 7 | 235
Hyperuricemia 7 | 35
Kidney Diseases 7 | 86
Pancreatitis 7 | 97
Rickets 7 | 42
nasopharyngeal carcinoma 7 | 1,056
spina bifida 7 | 1,064
urothelial carcinoma 7 | 318
Endometriosis 6 | 535
mucosa-associated lymphoid tissue lymphoma 6 | 480

Tissue

Digestive Tract 139 | 18,473
Urinary Tract 139 | 18,444
Endocrine System 138 | 18,512
Female tissues 138 | 18,647
Nervous System 138 | 18,561
Liver and Pancreas 137 | 18,136
Skin and soft tissues 136 | 18,115
Blood and immune system 133 | 17,995
Cardiovascular System 133 | 17,958
Male tissues 130 | 17,969
Respiratory system 128 | 17,484

Target Family

Non-IDG 70 | 11,971
Transporter 34 | 473
Enzyme 33 | 4,146
Ion Channel 3 | 341
Kinase 1 | 634

Compartment GO Term

Cluster of actin-based cell pr... 141 | 141
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Stereocilin STRC Tbio Non-IDG 35.9 7
Solute carrier family 13 member 1 SLC13A1 Tbio Transporter -1.70334 62.7 18
Epidermal growth factor receptor kinase substrate 8 EPS8 Tbio Enzyme -1.80380 77.2 248
Ileal sodium/bile acid cotransporter SLC10A2 Tchem Transporter -2.60727 417.5 121
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
Emerin EMD Tbio Non-IDG -2.77469 617.6 238
Sodium-dependent phosphate transporter 2 SLC20A2 Tbio Transporter -2.18737 165.3 97
Serotransferrin TF Tchem Non-IDG -4.13136 13124.3 952
Glutamyl aminopeptidase ENPEP Tchem Enzyme -2.81004 644.6 267
Solute carrier family 15 member 1 SLC15A1 Tchem Transporter -2.70013 532.5 167