Development Level

Tbio 40 | 11,651
Tchem 9 | 1,388
Tdark 5 | 6,593
Tclin 2 | 612

IMPC Phenotype

preweaning lethality, complete... 8 | 979
preweaning lethality, incomple... 4 | 499
abnormal behavior 2 | 298
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal skin coloration 1 | 25
absent startle reflex 1 | 24
absent teeth 1 | 3
cardiovascular system phenotyp... 1 | 36
decreased circulating calcium ... 1 | 36
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating unsatura... 1 | 2
decreased eosinophil cell numb... 1 | 24
decreased grip strength 1 | 116
decreased large unstained cell... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
edema 1 | 59
embryonic lethality prior to t... 1 | 278
female infertility 1 | 60
hemorrhage 1 | 23
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased exploration in new e... 1 | 8
increased heart rate variabili... 1 | 7
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
tremors 1 | 39

Disease

Carcinoma 37 | 11,493
ovarian cancer 35 | 8,520
glioblastoma 34 | 5,792
medulloblastoma, large-cell 32 | 6,241
osteosarcoma 32 | 7,950
psoriasis 28 | 6,694
atypical teratoid / rhabdoid tumor 27 | 5,112
primitive neuroectodermal tumor 22 | 3,035
ependymoma 21 | 4,679
adult high grade glioma 20 | 3,801
group 3 medulloblastoma 20 | 4,104
lung cancer 20 | 4,740
intraductal papillary-mucinous neoplasm (IPMN) 19 | 3,291
pancreatic cancer 19 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
invasive ductal carcinoma 17 | 2,951
Cancer 16 | 2,499
non-small cell lung cancer 16 | 2,890
Astrocytoma, Pilocytic 15 | 3,081
Breast cancer 15 | 3,578
lung adenocarcinoma 14 | 2,716
adrenocortical carcinoma 13 | 1,428
colon cancer 13 | 1,478
malignant mesothelioma 13 | 3,232
Kidney cancer 11 | 2,613
oligodendroglioma 11 | 2,850
ulcerative colitis 11 | 1,819
breast carcinoma 10 | 1,638
ductal carcinoma in situ 10 | 1,745
subependymal giant cell astrocytoma 10 | 2,287
Endometriosis 9 | 540
Multiple myeloma 9 | 1,332
astrocytic glioma 9 | 2,597
interstitial cystitis 9 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
pediatric high grade glioma 9 | 1,064
Atopic dermatitis 8 | 952
Pick disease 7 | 1,894
Schizophrenia 7 | 1,160
dermatomyositis 7 | 966
group 4 medulloblastoma 7 | 1,855
juvenile dermatomyositis 7 | 1,187
lung carcinoma 7 | 2,843
nasopharyngeal carcinoma 7 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
primary pancreatic ductal adenocarcinoma 7 | 1,109
acute quadriplegic myopathy 6 | 1,158
astrocytoma 6 | 1,146
esophageal adenocarcinoma 6 | 737
non primary Sjogren syndrome sicca 6 | 891
progressive supranuclear palsy 6 | 676
tuberculosis 6 | 2,010
Autosomal recessive predisposition 5 | 1,442
Waldenstrons macroglobulinemia 5 | 765
active Crohn's disease 5 | 922
diabetes mellitus 5 | 1,728
medulloblastoma 5 | 720
Down syndrome 4 | 499
Epilepsy 4 | 792
Liver Cirrhosis, Experimental 4 | 769
Liver cancer 4 | 604
Microcephaly 4 | 166
Multiple Sclerosis 4 | 540
Neoplasm Invasiveness 4 | 161
Polycystic ovary syndrome 4 | 360
Sloping forehead 4 | 46
Stomach Neoplasms 4 | 300
acute myeloid leukemia 4 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
cystic fibrosis 4 | 1,696
Crohn's disease 3 | 321
Duchenne muscular dystrophy 3 | 601
Focal glomerulosclerosis 3 | 37
Glomerulosclerosis, Focal Segmental 3 | 28
Intellectual disability 3 | 1,016
Melanoma 3 | 711
Neoplasm Metastasis 3 | 168
Prenatal onset 3 | 139
Proteinuria 3 | 144
Renal Cell Carcinoma 3 | 214
Rheumatoid arthritis 3 | 1,191
Seizures 3 | 596
Small head 3 | 374
cutaneous lupus erythematosus 3 | 1,057
gastric cancer 3 | 459
gastric carcinoma 3 | 807
hereditary spastic paraplegia 3 | 318
pancreatic carcinoma 3 | 562
posterior fossa group A ependymoma 3 | 468
primary Sjogren syndrome 3 | 735
spina bifida 3 | 1,074
Arthritis 2 | 290
Glaucoma 2 | 239
Mental Depression 2 | 333
chronic rhinosinusitis 2 | 512
hepatocellular carcinoma 2 | 547
nephrosclerosis 2 | 333
non diabetic and post-ischemic heart failure 2 | 200
pituitary cancer 2 | 1,972
urothelial carcinoma 2 | 318

Tissue

Endocrine System 56 | 18,159
Blood and immune system 55 | 16,909
Digestive Tract 55 | 17,369
Urinary Tract 55 | 16,678
Female tissues 54 | 17,400
Nervous System 54 | 16,725
Skin and soft tissues 54 | 17,230
Liver and Pancreas 53 | 16,750
Male tissues 53 | 17,142
Respiratory system 53 | 16,393
Cardiovascular System 51 | 15,192

Target Family

Non-IDG 35 | 12,091
Enzyme 12 | 4,145
Kinase 7 | 634
Ion Channel 1 | 344
oGPCR 1 | 421

Compartment GO Term

Cleavage furrow 56 | 56
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.33715 23.1 275
Myosin light chain kinase, smooth muscle MYLK Tchem Kinase -2.81312 694.0 219
Fibronectin type III and SPRY domain-containing protein 1 FSD1 Tbio Non-IDG -1.38197 23.9 160
Pleckstrin homology domain-containing family G member 6 PLEKHG6 Tbio Non-IDG -0.56736 4.94 109
Rab11 family-interacting protein 4 RAB11FIP4 Tbio Non-IDG -0.68187 5.48 43
Ras-related protein Rab-11A RAB11A Tbio Enzyme -2.65458 432.1 352
Protein phosphatase Slingshot homolog 1 SSH1 Tbio Enzyme -1.45823 27.6 148
Serine/threonine-protein kinase PLK1 PLK1 Tchem Kinase -3.09610 1271.1 856
Ras-related protein Ral-A RALA Tbio Enzyme -2.22188 169.9 225
5-hydroxytryptamine receptor 3A HTR3A Tclin Ion Channel -3.38661 2426.7 262