Development Level

Tbio 56 | 10,625
Tchem 10 | 1,890
Tclin 2 | 602
Tdark 2 | 7,003

IMPC Term

decreased total body fat amoun... 5 | 186
abnormal behavior 4 | 226
abnormal lens morphology 4 | 73
increased circulating HDL chol... 3 | 63
increased circulating alkaline... 3 | 119
increased or absent threshold ... 3 | 128
abnormal bone structure 2 | 131
abnormal sleep behavior 2 | 63
cardiovascular system phenotyp... 2 | 35
cataract 2 | 26
decreased body length 2 | 108
decreased bone mineral content 2 | 157
decreased bone mineral density 2 | 126
decreased grip strength 2 | 123
decreased lean body mass 2 | 195
decreased mean corpuscular vol... 2 | 50
hyperactivity 2 | 108
increased circulating LDL chol... 2 | 15
increased circulating potassiu... 2 | 31
increased circulating sodium l... 2 | 71
preweaning lethality, complete... 2 | 633
thrombocytopenia 2 | 46
abnormal QRS complex 1 | 25
abnormal femur morphology 1 | 14
abnormal nail morphology 1 | 7
abnormal retinal blood vessel ... 1 | 18
absent pinna reflex 1 | 21
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating calcium ... 1 | 33
decreased circulating fructosa... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating serum al... 1 | 79
decreased circulating triglyce... 1 | 83
decreased heart rate variabili... 1 | 11
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular hem... 1 | 19
decreased prepulse inhibition 1 | 52
decreased vertical activity 1 | 22
embryonic lethality prior to t... 1 | 187
female infertility 1 | 34
hypoactivity 1 | 89
impaired pupillary reflex 1 | 14
increased circulating choleste... 1 | 53
increased circulating free fat... 1 | 17
increased circulating phosphat... 1 | 24
increased erythrocyte cell num... 1 | 26
increased grip strength 1 | 83
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
male infertility 1 | 62
mydriasis 1 | 9
persistence of hyaloid vascula... 1 | 22
preweaning lethality, incomple... 1 | 260
short tibia 1 | 82
tremors 1 | 34

Disease

ovarian cancer 43 | 8,492
osteosarcoma 42 | 7,933
psoriasis 37 | 6,685
medulloblastoma, large-cell 36 | 6,234
glioblastoma 34 | 5,572
atypical teratoid / rhabdoid tumor 28 | 4,369
pilocytic astrocytoma 23 | 3,086
Cancer 22 | 2,346
Pick disease 21 | 1,893
lung cancer 20 | 4,473
Breast cancer 19 | 3,099
pediatric high grade glioma 19 | 2,712
primitive neuroectodermal tumor 19 | 3,031
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,289
oligodendroglioma 18 | 2,849
astrocytoma 16 | 1,493
ependymoma 16 | 2,514
subependymal giant cell astrocytoma 16 | 2,287
Carcinoma 15 | 2,147
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,956
lung carcinoma 15 | 2,844
malignant mesothelioma 15 | 3,163
non-small cell lung cancer 14 | 2,798
pancreatic cancer 14 | 2,300
invasive ductal carcinoma 13 | 2,950
Multiple myeloma 12 | 1,328
diabetes mellitus 12 | 1,663
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,988
astrocytic glioma 11 | 2,241
lung adenocarcinoma 11 | 2,714
pituitary cancer 11 | 1,972
tuberculosis 11 | 1,563
Alzheimer's disease 10 | 644
acute quadriplegic myopathy 10 | 1,157
interstitial cystitis 10 | 2,299
medulloblastoma 10 | 1,524
adult high grade glioma 9 | 2,148
dermatomyositis 8 | 967
ductal carcinoma in situ 8 | 1,745
Parkinson's disease 7 | 364
Waldenstrons macroglobulinemia 7 | 765
group 3 medulloblastoma 7 | 2,254
juvenile dermatomyositis 7 | 1,189
posterior fossa group A ependymoma 7 | 1,511
posterior fossa group B ependymoma 7 | 1,530
Kidney disease 6 | 397
Neurodegenerative disease 6 | 383
Rheumatoid Arthritis 6 | 1,171
Vascular disease 6 | 281
adrenocortical carcinoma 6 | 1,427
breast carcinoma 6 | 1,614
cystic fibrosis 6 | 1,670
esophageal adenocarcinoma 6 | 737
primary pancreatic ductal adenocarcinoma 6 | 1,271
ulcerative colitis 6 | 2,087
Down syndrome 5 | 548
Mammary Neoplasms 5 | 410
progressive supranuclear palsy 5 | 674
sonic hedgehog group medulloblastoma 5 | 1,482
Amyotrophic Lateral Sclerosis 4 | 432
Atopic dermatitis 4 | 944
Bladder Neoplasm 4 | 109
Duchenne muscular dystrophy 4 | 602
Neoplasm Invasiveness 4 | 127
Neuropathy 4 | 210
Prostatic Neoplasms 4 | 471
Renal Cell Carcinoma 4 | 199
Stomach Neoplasms 4 | 282
active Crohn's disease 4 | 918
acute T cell leukemia 4 | 17
atypical teratoid/rhabdoid tumor 4 | 1,095
pancreatic carcinoma 4 | 567
substance-related disorder 4 | 105
urothelial carcinoma 4 | 318
Adenocarcinoma 3 | 115
Adenoma 3 | 165
Anemia 3 | 252
Dementia 3 | 129
Diffuse large B-cell lymphoma 3 | 42
Gaucher disease type 1 3 | 171
Glaucoma 3 | 135
Heart disease 3 | 279
Influenza 3 | 142
Liver disease 3 | 219
Lysosomal storage disease 3 | 11
Melanoma 3 | 261
Mouth Neoplasms 3 | 44
Multiple Sclerosis 3 | 498
Myocardial Ischemia 3 | 169
Pain agnosia 3 | 99
colon cancer 3 | 1,475
gastric carcinoma 3 | 832
group 4 medulloblastoma 3 | 1,875
interstitial lung disease 3 | 292
nasopharyngeal carcinoma 3 | 1,056
non primary Sjogren syndrome sicca 3 | 840
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
Esophageal carcinoma 2 | 5
glioblastoma multiforme 2 | 347
non-small cell lung carcinoma 2 | 413

Tissue

Endocrine System 70 | 18,512
Blood and immune system 69 | 17,995
Cardiovascular System 69 | 17,958
Digestive Tract 69 | 18,473
Female tissues 69 | 18,647
Liver and Pancreas 69 | 18,136
Nervous System 69 | 18,561
Male tissues 68 | 17,969
Skin and soft tissues 68 | 18,115
Urinary Tract 68 | 18,444
Respiratory system 67 | 17,484

Target Family

Non-IDG 53 | 11,969
Enzyme 10 | 4,146
Kinase 3 | 634
Transporter 2 | 473
Epigenetic 1 | 242
Ion Channel 1 | 341

Compartment GO Term

Clathrin coat 70 | 70
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phosphatidylinositol-binding clathrin assembly protein PICALM Tbio Non-IDG -1.91723 81.1 124
Disabled homolog 2 DAB2 Tbio Non-IDG -2.24622 174.6 226
Clathrin heavy chain 2 CLTCL1 Tbio Non-IDG -1.27222 21.4 27
Adaptin ear-binding coat-associated protein 2 NECAP2 Tdark Non-IDG 0.03 1.26 31
AP-1 complex subunit mu-2 AP1M2 Tbio Non-IDG -2.53980 336.4 53
Sorting nexin-9 SNX9 Tbio Non-IDG -1.97326 95.2 203
Stonin-2 STON2 Tbio Non-IDG -1.42550 28.9 9
Epsin-1 EPN1 Tbio Non-IDG -1.49983 30.4 133
Transforming acidic coiled-coil-containing protein 3 TACC3 Tbio Non-IDG -1.94281 87.1 189
ADP-ribosylation factor-binding protein GGA1 GGA1 Tbio Non-IDG -1.90352 78.7 139