Development Level

Tbio 59 | 11,445
Tchem 6 | 1,598
Tclin 3 | 613
Tdark 3 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal behavior 4 | 298
decreased total body fat amoun... 4 | 207
preweaning lethality, incomple... 4 | 499
abnormal lens morphology 3 | 81
increased circulating alkaline... 3 | 122
abnormal bone structure 2 | 187
abnormal sleep behavior 2 | 70
cardiovascular system phenotyp... 2 | 36
cataract 2 | 92
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular hem... 2 | 50
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
hyperactivity 2 | 148
increased circulating HDL chol... 2 | 80
increased circulating sodium l... 2 | 71
increased or absent threshold ... 2 | 101
persistence of hyaloid vascula... 2 | 33
thrombocytopenia 2 | 56
abnormal cecum morphology 1 | 7
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal eye anterior chamber ... 1 | 9
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal heart shape 1 | 5
abnormal nail morphology 1 | 8
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal outer nuclear... 1 | 3
abnormal seminal vesicle morph... 1 | 114
abnormal sensory capabilities-... 1 | 8
absent pinna reflex 1 | 23
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased heart rate variabili... 1 | 13
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased monocyte cell number 1 | 8
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged cecum 1 | 5
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
female infertility 1 | 60
hydrometra 1 | 53
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
increased circulating LDL chol... 1 | 13
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased erythrocyte cell num... 1 | 39
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
male infertility 1 | 123
mydriasis 1 | 6
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
small superior vagus ganglion 1 | 74
tremors 1 | 39

Disease

Carcinoma 54 | 11,493
ovarian cancer 44 | 8,520
osteosarcoma 41 | 7,950
medulloblastoma, large-cell 37 | 6,241
psoriasis 37 | 6,694
glioblastoma 34 | 5,792
atypical teratoid / rhabdoid tumor 30 | 5,112
ependymoma 26 | 4,679
adult high grade glioma 23 | 3,801
Breast cancer 22 | 3,578
Cancer 22 | 2,499
astrocytic glioma 22 | 2,597
lung cancer 22 | 4,740
Astrocytoma, Pilocytic 21 | 3,081
Pick disease 21 | 1,894
oligodendroglioma 19 | 2,850
primitive neuroectodermal tumor 18 | 3,035
group 3 medulloblastoma 17 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
malignant mesothelioma 17 | 3,232
subependymal giant cell astrocytoma 17 | 2,287
Cataract 8 multiple types 16 | 33
lung carcinoma 16 | 2,843
non-small cell lung cancer 16 | 2,890
Kidney cancer 15 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
invasive ductal carcinoma 14 | 2,951
pancreatic cancer 14 | 2,398
diabetes mellitus 13 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
pituitary cancer 12 | 1,972
Multiple myeloma 11 | 1,332
acute quadriplegic myopathy 11 | 1,158
interstitial cystitis 11 | 2,312
tuberculosis 11 | 2,010
Autosomal recessive predisposition 10 | 1,442
lung adenocarcinoma 10 | 2,716
Alzheimer's disease 9 | 658
ductal carcinoma in situ 9 | 1,745
Intellectual disability 8 | 1,016
Schizophrenia 8 | 1,160
Breast Neoplasms 7 | 445
Dull intelligence 7 | 645
Liver cancer 7 | 604
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Neurodegenerative disease 7 | 414
Parkinson's disease 7 | 392
Poor school performance 7 | 645
Rheumatoid arthritis 7 | 1,191
Vascular disease 7 | 319
adrenocortical carcinoma 7 | 1,428
breast carcinoma 7 | 1,638
dermatomyositis 7 | 966
primary pancreatic ductal adenocarcinoma 7 | 1,109
Kidney disease 6 | 430
Major Depressive Disorder 6 | 301
Mammary Neoplasms 6 | 425
Melanoma 6 | 711
Neoplasm Invasiveness 6 | 161
Stomach Neoplasms 6 | 300
Waldenstrons macroglobulinemia 6 | 765
astrocytoma 6 | 1,146
cystic fibrosis 6 | 1,696
esophageal adenocarcinoma 6 | 737
juvenile dermatomyositis 6 | 1,187
Alcoholic Intoxication, Chronic 5 | 289
Amyotrophic lateral sclerosis 5 | 451
Bladder Neoplasm 5 | 112
Oculocerebrorenal syndrome 5 | 29
Prostatic Neoplasms 5 | 495
Renal Cell Carcinoma 5 | 214
Skin cancer 5 | 469
Unipolar Depression 5 | 250
Urinary Bladder Neoplasms 5 | 114
group 4 medulloblastoma 5 | 1,855
pediatric high grade glioma 5 | 1,064
progressive supranuclear palsy 5 | 676
Adenocarcinoma 4 | 122
Adenoma 4 | 167
Atopic dermatitis 4 | 952
Congenital pes cavus 4 | 88
DOID:2627 4 | 94
Decreased tendon reflex 4 | 122
Down syndrome 4 | 499
Epilepsy 4 | 792
Gaucher disease type 1 4 | 180
Glaucoma 4 | 239
Heart disease 4 | 306
Liver Cirrhosis, Experimental 4 | 769
Lung Neoplasms 4 | 232
Neuropathy 4 | 261
Pain agnosia 4 | 104
active Crohn's disease 4 | 922
acute T cell leukemia 4 | 17
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
substance-related disorder 4 | 162
ulcerative colitis 4 | 1,819
urothelial carcinoma 4 | 318

Tissue

Female tissues 70 | 17,400
Digestive Tract 69 | 17,369
Skin and soft tissues 69 | 17,230
Endocrine System 67 | 18,159
Male tissues 67 | 17,142
Blood and immune system 66 | 16,909
Liver and Pancreas 66 | 16,750
Nervous System 66 | 16,725
Respiratory system 66 | 16,393
Urinary Tract 66 | 16,678
Cardiovascular System 63 | 15,192

Target Family

Non-IDG 54 | 12,091
Enzyme 9 | 4,145
Kinase 4 | 634
Transporter 2 | 473
Epigenetic 1 | 242
Ion Channel 1 | 344

Compartment GO Term

Clathrin coat 71 | 71
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transforming acidic coiled-coil-containing protein 3 TACC3 Tbio Non-IDG -1.99617 101.2 222
Stonin-2 STON2 Tbio Non-IDG -1.43585 30.0 11
Clathrin heavy chain 2 CLTCL1 Tbio Non-IDG -1.29555 21.3 39
Serotransferrin TF Tbio Non-IDG -4.15070 13447.9 1168
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.43851 2558.3 1677
Synaptojanin-1 SYNJ1 Tbio Non-IDG -1.76329 62.0 93
Ras-related protein Rab-7a RAB7A Tbio Enzyme -2.66545 435.4 248
Clathrin heavy chain 1 CLTC Tbio Non-IDG -1.66258 38.8 231
Keratin, type I cuticular Ha7 KRT37 Tdark Non-IDG -1.63304 35.5 15
Putative tyrosine-protein phosphatase auxilin DNAJC6 Tbio Enzyme -1.74103 58.7 98