Development Level

Tbio 293 | 10,625
Tdark 106 | 7,003
Tchem 35 | 1,890
Tclin 12 | 602

Collection

Eligible Kinase Proteins 6 | 134
Eligible non-olfactory GPCR Proteins 4 | 143
Eligible Ion Channel Proteins 2 | 117

IMPC Term

preweaning lethality, complete... 25 | 633
decreased body weight 9 | 174
preweaning lethality, incomple... 9 | 260
abnormal behavior 8 | 226
embryonic lethality prior to t... 7 | 187
hyperactivity 6 | 108
increased fasted circulating g... 6 | 68
decreased bone mineral content 5 | 157
decreased lean body mass 5 | 195
increased mean corpuscular hem... 5 | 93
abnormal bone mineralization 4 | 55
abnormal retina morphology 4 | 100
decreased bone mineral density 4 | 126
decreased circulating triglyce... 4 | 83
decreased grip strength 4 | 123
decreased prepulse inhibition 4 | 52
impaired glucose tolerance 4 | 52
increased blood urea nitrogen ... 4 | 44
increased body weight 4 | 42
increased circulating HDL chol... 4 | 63
increased circulating alkaline... 4 | 119
increased circulating choleste... 4 | 53
increased mean corpuscular vol... 4 | 91
limb grasping 4 | 35
prenatal lethality prior to he... 4 | 64
decreased circulating amylase ... 3 | 24
decreased circulating choleste... 3 | 85
decreased circulating insulin ... 3 | 75
decreased mean corpuscular vol... 3 | 50
decreased startle reflex 3 | 48
hypoactivity 3 | 89
increased circulating chloride... 3 | 43
increased lean body mass 3 | 107
increased leukocyte cell numbe... 3 | 37
increased or absent threshold ... 3 | 128
increased total body fat amoun... 3 | 57
male infertility 3 | 62
abnormal QRS complex 2 | 25
abnormal bone structure 2 | 131
abnormal embryo size 2 | 112
abnormal embryo turning 2 | 15
abnormal nail morphology 2 | 7
abnormal respiratory quotient 2 | 9
abnormal retinal pigmentation 2 | 61
abnormal sleep behavior 2 | 63
cardiovascular system phenotyp... 2 | 35
decreased B cell number 2 | 30
decreased CD4-positive, alpha ... 2 | 19
decreased circulating HDL chol... 2 | 77
decreased circulating free fat... 2 | 39
decreased circulating glucose ... 2 | 121
decreased circulating phosphat... 2 | 15
decreased hemoglobin content 2 | 53
decreased lumbar vertebrae num... 2 | 62
embryonic lethality prior to o... 2 | 148
increased bone mineral content 2 | 92
increased circulating aspartat... 2 | 17
increased circulating glycerol... 2 | 11
increased circulating iron lev... 2 | 25
increased circulating sodium l... 2 | 71
increased grip strength 2 | 83
increased prepulse inhibition 2 | 21
increased sacral vertebrae num... 2 | 62
increased startle reflex 2 | 38
short tibia 2 | 82
vertebral fusion 2 | 23
abnormal behavioral response t... 1 | 52
abnormal ear morphology 1 | 5
abnormal eye morphology 1 | 38
abnormal limb bud morphology 1 | 15
abnormal locomotor activation 1 | 26
abnormal neural tube closure 1 | 37
abnormal rib morphology 1 | 28
abnormal skin morphology 1 | 23
abnormal startle reflex 1 | 14
abnormal testis morphology 1 | 30
absent pinna reflex 1 | 21
convulsive seizures 1 | 11
decreased circulating chloride... 1 | 32
decreased eosinophil cell numb... 1 | 41
decreased exploration in new e... 1 | 9
decreased hematocrit 1 | 25
decreased red blood cell distr... 1 | 11
embryonic growth retardation 1 | 28
enlarged lymph nodes 1 | 27
hydrometra 1 | 13
impaired righting response 1 | 19
increased bone mineral density 1 | 52
increased circulating alanine ... 1 | 11
increased circulating amylase ... 1 | 13
increased circulating creatini... 1 | 29
increased circulating glucose ... 1 | 16
increased circulating magnesiu... 1 | 10
increased rib number 1 | 41
persistence of hyaloid vascula... 1 | 22
polycystic kidney 1 | 9
stereotypic behavior 1 | 3
straub tail 1 | 26
thrombocytopenia 1 | 46
trunk curl 1 | 15

Disease

osteosarcoma 194 | 7,933
ovarian cancer 176 | 8,484
posterior fossa group B ependymoma 140 | 1,530
medulloblastoma, large-cell 135 | 6,234
psoriasis 132 | 6,685
glioblastoma 123 | 5,572
atypical teratoid / rhabdoid tumor 99 | 4,369
lung cancer 86 | 4,466
Carcinoma 85 | 2,147
chronic rhinosinusitis 73 | 512
primitive neuroectodermal tumor 72 | 3,031
pediatric high grade glioma 70 | 2,712
nasopharyngeal carcinoma 69 | 1,056
lung adenocarcinoma 67 | 2,713
Breast cancer 66 | 3,094
lung carcinoma 64 | 2,844
malignant mesothelioma 62 | 3,162
Retinitis pigmentosa 61 | 153
pilocytic astrocytoma 61 | 3,086
group 3 medulloblastoma 59 | 2,254
Polydactyly 58 | 93
oligodendroglioma 58 | 2,849
astrocytic glioma 56 | 2,241
ependymoma 56 | 2,514
Pick disease 55 | 1,893
intraductal papillary-mucinous carcinoma (IPMC) 53 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 53 | 3,289
non-small cell lung cancer 51 | 2,798
Nephronophthisis 50 | 74
intraductal papillary-mucinous adenoma (IPMA) 50 | 2,956
invasive ductal carcinoma 50 | 2,950
Ciliopathy 49 | 57
Primary ciliary dyskinesia 46 | 73
group 4 medulloblastoma 43 | 1,875
Joubert syndrome 40 | 61
adult high grade glioma 39 | 2,148
pituitary cancer 39 | 1,972
Fundus dystrophy 38 | 77
interstitial cystitis 37 | 2,299
subependymal giant cell astrocytoma 37 | 2,287
medulloblastoma 36 | 1,524
pancreatic cancer 36 | 2,300
ulcerative colitis 36 | 2,087
Cancer 35 | 2,346
atypical teratoid/rhabdoid tumor 35 | 1,095
Intellectual disability 34 | 573
Bardet-Biedl Syndrome 33 | 40
Obesity 33 | 616
Situs Inversus 33 | 48
Cone dystrophy 32 | 57
ductal carcinoma in situ 32 | 1,745
Meckel syndrome 31 | 48
sonic hedgehog group medulloblastoma 30 | 1,482
colon cancer 29 | 1,475
breast carcinoma 28 | 1,614
tuberculosis 27 | 1,557
Asphyxiating thoracic dystrophy 25 | 32
Leber congenital amaurosis 25 | 72
astrocytoma 25 | 1,493
Blindness 24 | 84
Kartagener Syndrome 23 | 32
cone-rod dystrophy 22 | 56
adrenocortical carcinoma 21 | 1,427
cystic fibrosis 21 | 1,665
progressive supranuclear palsy 21 | 674
Male infertility 20 | 170
Polycystic kidney disease 20 | 54
Rheumatoid Arthritis 20 | 1,160
Senior-Loken syndrome 20 | 21
cystic fibrosis and chronic rhinosinusitis 20 | 213
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,795
primary pancreatic ductal adenocarcinoma 20 | 1,271
Cystic kidney disease 19 | 25
Endometriosis 19 | 535
active Crohn's disease 19 | 918
non primary Sjogren syndrome sicca 19 | 840
Schizophrenia 18 | 501
diabetes mellitus 18 | 1,663
spina bifida 18 | 1,064
Multiple myeloma 17 | 1,327
cutaneous lupus erythematosus 17 | 1,056
posterior fossa group A ependymoma 17 | 1,511
tuberculosis and treatment for 6 months 17 | 686
Hydrocephalus 16 | 60
Orofaciodigital syndrome 15 | 19
Meckel-Gruber syndrome 14 | 15
Sensenbrenner syndrome 14 | 15
Atopic dermatitis 13 | 944
Kidney disease 13 | 396
Retinal Degeneration 13 | 49
fibroadenoma 13 | 557
gastric cancer 13 | 430
Alzheimer's disease 12 | 644
Nonsyndromic deafness 11 | 121
acute myeloid leukemia 11 | 780
acute quadriplegic myopathy 11 | 1,157
dermatomyositis 11 | 933
gastric carcinoma 11 | 832
hepatocellular carcinoma 11 | 532
pancreatic carcinoma 11 | 567

Tissue

Nervous System 443 | 18,561
Female tissues 440 | 18,647
Urinary Tract 440 | 18,444
Digestive Tract 439 | 18,473
Endocrine System 439 | 18,512
Liver and Pancreas 436 | 18,136
Blood and immune system 435 | 17,995
Cardiovascular System 434 | 17,958
Male tissues 434 | 17,969
Skin and soft tissues 434 | 18,115
Respiratory system 429 | 17,484

Target Family

Non-IDG 312 | 11,971
Enzyme 59 | 4,146
Kinase 27 | 634
GPCR 15 | 406
Ion Channel 13 | 341
Transcription Factor 12 | 1,400
Transporter 7 | 473
Epigenetic 1 | 242

Compartment GO Term

Cilium 446 | 446
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
D(2) dopamine receptor DRD2 Tclin GPCR -3.24474 1775.2 248
Stereocilin STRC Tbio Non-IDG 35.9 7
Ropporin-1B ROPN1B Tbio Non-IDG 1.00 0.10 52
Cilia- and flagella-associated protein 77 CFAP77 Tdark Non-IDG 0.00000 11
Multicilin MCIDAS Tbio Non-IDG -2.00076 101.0 59
Centrosomal protein of 164 kDa CEP164 Tbio Non-IDG -0.96655 10.2 84
Short-wave-sensitive opsin 1 OPN1SW Tbio GPCR -1.90084 81.3 15
Protein C21orf2 C21orf2 Tbio Non-IDG -1.66840 37.4 95
Meiosis-specific nuclear structural protein 1 MNS1 Tbio Non-IDG -1.16311 14.2 55
Bardet-Biedl syndrome 7 protein BBS7 Tbio Non-IDG -1.02867 11.1 125