Development Level

Tbio 37 | 11,445
Tdark 6 | 6,588
Tchem 4 | 1,598
Tclin 1 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 15 | 979
abnormal behavior 6 | 298
embryonic lethality prior to t... 3 | 278
hypoactivity 3 | 132
abnormal embryo size 2 | 220
abnormal embryo turning 2 | 31
decreased fasted circulating g... 2 | 65
decreased lean body mass 2 | 135
embryonic growth retardation 2 | 106
enlarged lymph nodes 2 | 37
hyperactivity 2 | 148
impaired glucose tolerance 2 | 75
increased circulating chloride... 2 | 41
increased lean body mass 2 | 172
prenatal lethality prior to he... 2 | 87
preweaning lethality, incomple... 2 | 499
abnormal bone structure 1 | 187
abnormal embryo development 1 | 7
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal limb bud morphology 1 | 17
abnormal liver size 1 | 5
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pelvic girdle bone mo... 1 | 12
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal stomach morphology 1 | 10
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased grip strength 1 | 116
decreased lactate dehydrogenas... 1 | 16
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
increased bone mineral content 1 | 108
increased circulating free fat... 1 | 20
increased circulating glycerol... 1 | 9
increased circulating magnesiu... 1 | 10
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased heart rate variabili... 1 | 7
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 36
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
long tibia 1 | 25
male infertility 1 | 123
pale liver 1 | 6
pale yolk sac 1 | 25
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33

Disease

Carcinoma 36 | 11,493
ependymoma 26 | 4,679
osteosarcoma 26 | 7,950
ovarian cancer 26 | 8,520
Polydactyly 23 | 107
atypical teratoid / rhabdoid tumor 18 | 5,112
Ciliopathy 17 | 71
glioblastoma 16 | 5,792
psoriasis 16 | 6,694
medulloblastoma, large-cell 15 | 6,241
Asphyxiating thoracic dystrophy 14 | 44
lung cancer 13 | 4,740
group 3 medulloblastoma 12 | 4,104
Bardet-Biedl syndrome 11 | 51
Nephronophthisis 11 | 80
Sensenbrenner syndrome 11 | 17
chronic rhinosinusitis 11 | 512
malignant mesothelioma 11 | 3,232
Gastrointestinal Stromal Tumors 10 | 48
Jeune thoracic dystrophy 9 | 10
Kidney cancer 9 | 2,613
Short Rib-Polydactyly Syndrome 9 | 13
adult high grade glioma 9 | 3,801
primitive neuroectodermal tumor 9 | 3,035
Brachydactyly 8 | 156
Breast cancer 8 | 3,578
Congenital hypoplasia of penis 8 | 176
Ellis-Van Creveld syndrome 8 | 19
Short stature 8 | 531
Hydrocephalus 7 | 152
Pick disease 7 | 1,894
Intellectual disability 6 | 1,016
Obesity 6 | 678
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
lung carcinoma 6 | 2,843
medulloblastoma 6 | 720
Abnormality of the metaphyses 5 | 48
Autosomal recessive predisposition 5 | 1,442
Broad flat nasal bridge 5 | 236
Cancer 5 | 2,499
Cleft Lip 5 | 141
Cranioectodermal Dysplasia 5 | 5
Cryptorchidism 5 | 296
Joubert syndrome 5 | 66
Micromelia 5 | 58
Narrow thorax 5 | 53
Nasal bridge wide 5 | 236
Nevoid basal cell carcinoma syndrome 5 | 16
Respiratory Insufficiency 5 | 132
Retinitis Pigmentosa 5 | 226
Short rib-polydactyly syndrome, Verma-Naumoff type 5 | 5
Short-rib thoracic dysplasia 3 with or without polydactyly 5 | 9
Sternal anomalies 5 | 19
Ulnar polydactyly of fingers 5 | 47
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
non-small cell lung cancer 5 | 2,890
oligodendroglioma 5 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pediatric high grade glioma 5 | 1,064
Abnormal skeletal development 4 | 60
Abnormality of pelvic girdle bone morphology 4 | 37
Abnormality of the clavicle 4 | 14
Abnormality of the ribs 4 | 32
Abnormally small eyeball 4 | 97
Acrofacial dysostosis 4 | 8
Anteverted nostril 4 | 191
Cone-shaped epiphyses 4 | 24
Craniosynostosis 4 | 74
Decreased size of eyeball 4 | 97
Dull intelligence 4 | 645
Frontal bossing 4 | 157
Holoprosencephaly 4 | 56
Hypoplastic feet 4 | 66
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Microphthalmos 4 | 100
Nystagmus 4 | 317
Osteochondrodysplasias 4 | 72
Poor school performance 4 | 645
Respiratory function loss 4 | 121
Senior-Loken syndrome 4 | 22
Short thorax 4 | 21
cystic fibrosis and chronic rhinosinusitis 4 | 214
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung adenocarcinoma 4 | 2,716
pancreatic cancer 4 | 2,398
Astrocytoma, Pilocytic 3 | 3,081
Atopic dermatitis 3 | 952
Glaucoma 3 | 239
acute myeloid leukemia 3 | 783
astrocytic glioma 3 | 2,597
astrocytoma 3 | 1,146
cutaneous lupus erythematosus 3 | 1,057
dermatomyositis 3 | 966
hepatocellular carcinoma 3 | 547
invasive ductal carcinoma 3 | 2,951
nasopharyngeal carcinoma 3 | 1,058
primary pancreatic ductal adenocarcinoma 3 | 1,109
progressive supranuclear palsy 3 | 676

Tissue

Digestive Tract 48 | 17,369
Endocrine System 48 | 18,159
Female tissues 48 | 17,400
Liver and Pancreas 48 | 16,750
Male tissues 48 | 17,142
Nervous System 48 | 16,725
Respiratory system 48 | 16,393
Skin and soft tissues 48 | 17,230
Blood and immune system 47 | 16,909
Urinary Tract 47 | 16,678
Cardiovascular System 46 | 15,192

Target Family

Non-IDG 37 | 12,091
Transcription Factor 4 | 1,400
Enzyme 3 | 4,145
GPCR 2 | 408
Kinase 2 | 634

Compartment GO Term

Ciliary tip 48 | 48
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Intraflagellar transport protein 25 homolog HSPB11 Tbio Non-IDG -1.40552 26.1 61
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
WD repeat-containing protein 60 WDR60 Tbio Non-IDG -0.64761 3.98 23
Intraflagellar transport protein 52 homolog IFT52 Tbio Non-IDG -1.09507 12.7 13
Cytoplasmic dynein 2 heavy chain 1 DYNC2H1 Tbio Non-IDG -1.60757 39.5 23
Intraflagellar transport protein 140 homolog IFT140 Tbio Non-IDG -1.42568 23.3 45
Serine/threonine-protein kinase ICK ICK Tchem Kinase -2.63650 422.2 179
Sentan SNTN Tdark Non-IDG -0.71321 3.95 6
Dynein light chain roadblock-type 1 DYNLRB1 Tbio Non-IDG -2.23639 168.6 41
Dynein light chain roadblock-type 2 DYNLRB2 Tbio Non-IDG -0.65444 2.59 77