Development Level

Tbio 95 | 11,178
Tdark 41 | 6,569
Tclin 4 | 612
Tchem 2 | 1,885

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 12 | 979
preweaning lethality, incomple... 8 | 499
abnormal behavior 3 | 298
edema 3 | 59
embryonic lethality prior to t... 3 | 278
male infertility 3 | 123
abnormal embryo size 2 | 220
decreased body length 2 | 101
decreased body weight 2 | 161
decreased fasted circulating g... 2 | 65
hyperactivity 2 | 148
increased fasted circulating g... 2 | 76
abnormal coat appearance 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal forebrain morphology 1 | 10
abnormal hindbrain morphology 1 | 10
abnormal ileum morphology 1 | 2
abnormal limb morphology 1 | 13
abnormal lung morphology 1 | 26
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal response to tactile s... 1 | 17
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
anophthalmia 1 | 33
decreased B cell number 1 | 5
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating glucose ... 1 | 126
decreased circulating potassiu... 1 | 20
decreased grip strength 1 | 116
decreased lactate dehydrogenas... 1 | 16
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
hypoactivity 1 | 132
increased body weight 1 | 25
increased circulating chloride... 1 | 41
increased circulating magnesiu... 1 | 10
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
long tibia 1 | 25
microphthalmia 1 | 26
polycystic kidney 1 | 15
polydactyly 1 | 7
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97

Disease

Carcinoma 100 | 11,192
ependymoma 80 | 4,559
osteosarcoma 56 | 7,766
ovarian cancer 53 | 8,297
Primary ciliary dyskinesia 47 | 75
chronic rhinosinusitis 41 | 505
nasopharyngeal carcinoma 41 | 1,024
psoriasis 39 | 6,514
Kidney cancer 38 | 2,548
medulloblastoma, large-cell 37 | 6,086
atypical teratoid / rhabdoid tumor 35 | 4,971
glioblastoma 34 | 5,635
Ciliary Motility Disorders 30 | 38
Kartagener Syndrome 29 | 38
Situs Inversus 29 | 61
Breast cancer 28 | 3,469
lung adenocarcinoma 27 | 2,627
adult high grade glioma 24 | 3,701
Autosomal recessive predisposition 22 | 1,407
group 3 medulloblastoma 22 | 4,002
lung cancer 22 | 4,607
Ciliary Dyskinesia, Primary, 1 21 | 27
Liver cancer 19 | 589
astrocytic glioma 19 | 2,530
lung carcinoma 18 | 2,755
primitive neuroectodermal tumor 18 | 2,957
Astrocytoma, Pilocytic 17 | 3,006
Male infertility 17 | 199
Pick disease 16 | 1,856
Polydactyly 16 | 106
Nephronophthisis 15 | 79
malignant mesothelioma 15 | 3,135
Ciliopathy 14 | 71
Intellectual disability 14 | 998
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,872
non-small cell lung cancer 14 | 2,799
oligodendroglioma 14 | 2,768
pituitary cancer 14 | 1,915
Recurrent respiratory infections 12 | 138
Sinusitis 12 | 63
group 4 medulloblastoma 12 | 1,806
Cancer 11 | 2,388
Dull intelligence 11 | 634
Joubert syndrome 11 | 66
Low intelligence 11 | 634
Melanoma 11 | 689
Mental Retardation 11 | 634
Mental deficiency 11 | 634
Poor school performance 11 | 634
Schizophrenia 11 | 1,136
cystic fibrosis and chronic rhinosinusitis 11 | 211
Alzheimer's disease 10 | 640
Bronchiectasis 10 | 63
Obesity 10 | 655
Retinitis Pigmentosa 10 | 223
pancreatic cancer 10 | 2,322
tuberculosis 10 | 1,963
Asphyxiating thoracic dystrophy 9 | 44
Bardet-Biedl syndrome 9 | 51
Endometrial cancer 9 | 301
Hydrocephalus 9 | 148
Nystagmus 9 | 309
interstitial cystitis 9 | 2,237
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,902
invasive ductal carcinoma 9 | 2,867
Multiple myeloma 8 | 1,296
Situs ambiguus 8 | 22
Skin cancer 8 | 451
primary pancreatic ductal adenocarcinoma 8 | 1,071
Cataract 7 | 290
Congenital hypoplasia of penis 7 | 168
Electroretinogram abnormal 7 | 94
Epilepsy 7 | 775
Hypogonadism 7 | 169
Infertility 7 | 176
Lens Opacities 7 | 227
Meckel syndrome 7 | 46
Optic Atrophy 7 | 239
Short stature 7 | 514
colon cancer 7 | 1,428
cutaneous lupus erythematosus 7 | 1,016
diabetes mellitus 7 | 1,683
medulloblastoma 7 | 702
posterior fossa group B ependymoma 7 | 406
subependymal giant cell astrocytoma 7 | 2,230
DOID:2627 6 | 89
Fundus dystrophy 6 | 80
Meckel-Gruber syndrome 6 | 13
Multicystic Dysplastic Kidney 6 | 51
Orofaciodigital syndrome 6 | 21
Retinal Degeneration 6 | 103
Sensenbrenner syndrome 6 | 17
Short Rib-Polydactyly Syndrome 6 | 13
Ulnar polydactyly of fingers 6 | 46
adrenocortical carcinoma 6 | 1,385
cystic fibrosis 6 | 1,629
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,204
non primary Sjogren syndrome sicca 6 | 861
ulcerative colitis 6 | 1,765
Small head 5 | 366

Tissue

Endocrine System 141 | 18,159
Female tissues 134 | 17,400
Respiratory system 133 | 16,393
Male tissues 132 | 17,142
Skin and soft tissues 132 | 17,230
Digestive Tract 128 | 17,369
Nervous System 127 | 16,725
Urinary Tract 125 | 16,678
Liver and Pancreas 123 | 16,750
Blood and immune system 122 | 16,909
Cardiovascular System 103 | 15,192

Target Family

Non-IDG 123 | 12,091
Enzyme 14 | 4,145
Kinase 3 | 634
Transcription Factor 2 | 1,400

Compartment GO Term

Ciliary plasm 142 | 142
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein monoglycylase TTLL8 TTLL8 Tdark Enzyme -0.12494 0.88 19
Cilia- and flagella-associated protein 251 WDR66 Tbio Non-IDG -0.15127 1.56 72
Dynein assembly factor with WDR repeat domains 1 DAW1 Tdark Non-IDG -0.80163 6.92 13
Dynein heavy chain 5, axonemal DNAH5 Tbio Non-IDG -1.46000 27.2 32
Kinesin-like protein KIF17 KIF17 Tbio Non-IDG -2.01401 107.8 73
Centriole, cilia and spindle-associated protein CCSAP Tbio Non-IDG -1.93256 89.5 55
Dynein heavy chain 2, axonemal DNAH2 Tdark Non-IDG -0.65482 4.13 58
Dynein light chain roadblock-type 2 DYNLRB2 Tbio Non-IDG -0.65444 2.59 77
Dynein heavy chain 1, axonemal DNAH1 Tbio Non-IDG -1.30285 17.4 21
Tau-tubulin kinase 2 TTBK2 Tbio Kinase -1.26107 19.5 146