Development Level

Tbio 227 | 10,625
Tdark 67 | 7,003
Tchem 18 | 1,890
Tclin 12 | 602

Collection

Eligible Kinase Proteins 4 | 134
Eligible non-olfactory GPCR Proteins 4 | 143
Eligible Ion Channel Proteins 1 | 117

IMPC Term

preweaning lethality, complete... 20 | 633
preweaning lethality, incomple... 8 | 260
abnormal behavior 6 | 226
decreased body weight 5 | 174
embryonic lethality prior to t... 5 | 187
increased fasted circulating g... 5 | 68
hyperactivity 4 | 108
increased body weight 4 | 42
increased mean corpuscular hem... 4 | 93
prenatal lethality prior to he... 4 | 64
decreased bone mineral content 3 | 157
decreased bone mineral density 3 | 126
decreased circulating insulin ... 3 | 75
decreased grip strength 3 | 123
decreased lean body mass 3 | 195
impaired glucose tolerance 3 | 52
increased circulating HDL chol... 3 | 63
increased circulating choleste... 3 | 53
increased lean body mass 3 | 107
increased mean corpuscular vol... 3 | 91
increased total body fat amoun... 3 | 57
abnormal QRS complex 2 | 25
abnormal embryo size 2 | 112
abnormal embryo turning 2 | 15
abnormal nail morphology 2 | 7
abnormal sleep behavior 2 | 63
cardiovascular system phenotyp... 2 | 35
decreased CD4-positive, alpha ... 2 | 19
decreased circulating glucose ... 2 | 121
decreased circulating triglyce... 2 | 83
decreased mean corpuscular vol... 2 | 50
decreased prepulse inhibition 2 | 52
decreased startle reflex 2 | 48
embryonic lethality prior to o... 2 | 148
hypoactivity 2 | 89
increased blood urea nitrogen ... 2 | 44
increased bone mineral content 2 | 92
increased circulating alkaline... 2 | 119
increased circulating aspartat... 2 | 17
increased circulating chloride... 2 | 43
increased circulating glycerol... 2 | 11
increased grip strength 2 | 83
increased or absent threshold ... 2 | 128
increased prepulse inhibition 2 | 21
increased startle reflex 2 | 38
male infertility 2 | 62
short tibia 2 | 82
abnormal behavioral response t... 1 | 52
abnormal eye morphology 1 | 38
abnormal gait 1 | 51
abnormal hindbrain development 1 | 24
abnormal lens morphology 1 | 73
abnormal limb bud morphology 1 | 15
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal pelvic girdle bone mo... 1 | 11
abnormal pericardium morpholog... 1 | 11
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal startle reflex 1 | 14
abnormal testis morphology 1 | 30
abnormal whole-body plethysmog... 1 | 4
absent heartbeat 1 | 6
convulsive seizures 1 | 11
decreased circulating bilirubi... 1 | 14
decreased circulating chloride... 1 | 32
decreased circulating potassiu... 1 | 17
decreased eosinophil cell numb... 1 | 41
decreased exploration in new e... 1 | 9
decreased hemoglobin content 1 | 53
decreased lumbar vertebrae num... 1 | 62
decreased red blood cell distr... 1 | 11
embryonic growth retardation 1 | 28
enlarged lymph nodes 1 | 27
hydrometra 1 | 13
increased blood uric acid leve... 1 | 5
increased bone mineral density 1 | 52
increased circulating alanine ... 1 | 11
increased circulating amylase ... 1 | 13
increased circulating creatini... 1 | 29
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased circulating magnesiu... 1 | 10
increased circulating potassiu... 1 | 31
increased circulating serum al... 1 | 25
increased heart rate variabili... 1 | 4
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 37
increased rib number 1 | 41
increased sacral vertebrae num... 1 | 62
pale yolk sac 1 | 12
pallor 1 | 13
polydactyly 1 | 22
small superior vagus ganglion 1 | 20
small testis 1 | 37
straub tail 1 | 26
thrombocytopenia 1 | 46
vertebral fusion 1 | 23

Disease

osteosarcoma 141 | 7,933
ovarian cancer 136 | 8,484
posterior fossa group B ependymoma 105 | 1,530
medulloblastoma, large-cell 96 | 6,234
psoriasis 94 | 6,685
glioblastoma 89 | 5,572
atypical teratoid / rhabdoid tumor 75 | 4,369
Carcinoma 63 | 2,147
lung cancer 59 | 4,466
chronic rhinosinusitis 57 | 512
Polydactyly 53 | 93
nasopharyngeal carcinoma 53 | 1,056
primitive neuroectodermal tumor 51 | 3,031
pediatric high grade glioma 49 | 2,712
lung adenocarcinoma 46 | 2,713
Breast cancer 45 | 3,094
lung carcinoma 45 | 2,844
malignant mesothelioma 45 | 3,162
pilocytic astrocytoma 45 | 3,086
Primary ciliary dyskinesia 44 | 73
Pick disease 42 | 1,893
Retinitis pigmentosa 42 | 153
group 3 medulloblastoma 42 | 2,254
oligodendroglioma 42 | 2,849
Ciliopathy 41 | 57
Nephronophthisis 41 | 74
ependymoma 41 | 2,514
astrocytic glioma 40 | 2,241
intraductal papillary-mucinous carcinoma (IPMC) 39 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 37 | 2,956
invasive ductal carcinoma 37 | 2,950
non-small cell lung cancer 37 | 2,798
Situs Inversus 33 | 48
intraductal papillary-mucinous neoplasm (IPMN) 31 | 3,289
Bardet-Biedl Syndrome 30 | 40
Joubert syndrome 30 | 61
group 4 medulloblastoma 30 | 1,875
Fundus dystrophy 29 | 77
Intellectual disability 29 | 573
Obesity 29 | 616
adult high grade glioma 28 | 2,148
interstitial cystitis 28 | 2,299
medulloblastoma 28 | 1,524
pancreatic cancer 28 | 2,300
pituitary cancer 27 | 1,972
Cancer 25 | 2,346
subependymal giant cell astrocytoma 25 | 2,287
ulcerative colitis 25 | 2,087
Cone dystrophy 24 | 57
atypical teratoid/rhabdoid tumor 24 | 1,095
Asphyxiating thoracic dystrophy 23 | 32
Kartagener Syndrome 23 | 32
Meckel syndrome 23 | 48
ductal carcinoma in situ 21 | 1,745
sonic hedgehog group medulloblastoma 21 | 1,482
Senior-Loken syndrome 19 | 21
breast carcinoma 19 | 1,614
tuberculosis 19 | 1,557
Leber congenital amaurosis 18 | 72
primary pancreatic ductal adenocarcinoma 18 | 1,271
colon cancer 17 | 1,475
Male infertility 16 | 170
astrocytoma 16 | 1,493
cystic fibrosis 16 | 1,665
cystic fibrosis and chronic rhinosinusitis 16 | 213
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,795
progressive supranuclear palsy 16 | 674
Cystic kidney disease 15 | 25
adrenocortical carcinoma 15 | 1,427
cutaneous lupus erythematosus 15 | 1,056
non primary Sjogren syndrome sicca 15 | 840
Meckel-Gruber syndrome 14 | 15
Orofaciodigital syndrome 14 | 19
Schizophrenia 14 | 501
Blindness 13 | 84
Hydrocephalus 13 | 60
Polycystic kidney disease 13 | 54
Rheumatoid Arthritis 13 | 1,160
active Crohn's disease 13 | 918
cone-rod dystrophy 13 | 56
tuberculosis and treatment for 6 months 13 | 686
Sensenbrenner syndrome 12 | 15
Multiple myeloma 11 | 1,327
Retinal Degeneration 11 | 49
diabetes mellitus 11 | 1,663
fibroadenoma 11 | 557
posterior fossa group A ependymoma 11 | 1,511
spina bifida 11 | 1,064
Ellis-Van Creveld syndrome 10 | 18
Kidney cancer 10 | 118
Renal dysplasia and retinal aplasia (disorder) 10 | 10
acute myeloid leukemia 10 | 780
Endometriosis 9 | 535
Hydrolethalus syndrome 9 | 128
Kidney disease 9 | 396
acute quadriplegic myopathy 9 | 1,157
gastric cancer 9 | 430
hepatocellular carcinoma 9 | 532
Waldenstrons macroglobulinemia 8 | 765
gastric carcinoma 8 | 832

Tissue

Nervous System 322 | 18,561
Female tissues 319 | 18,647
Urinary Tract 319 | 18,444
Blood and immune system 318 | 17,995
Digestive Tract 318 | 18,473
Endocrine System 318 | 18,512
Liver and Pancreas 317 | 18,136
Cardiovascular System 316 | 17,958
Male tissues 316 | 17,969
Skin and soft tissues 314 | 18,115
Respiratory system 311 | 17,484

Target Family

Non-IDG 239 | 11,971
Enzyme 36 | 4,146
Kinase 17 | 634
GPCR 14 | 406
Ion Channel 8 | 341
Transcription Factor 6 | 1,400
Transporter 3 | 473
Epigenetic 1 | 242

Compartment GO Term

Ciliary part 324 | 324
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
D(2) dopamine receptor DRD2 Tclin GPCR -3.24474 1775.2 248
Centrosomal protein of 164 kDa CEP164 Tbio Non-IDG -0.96655 10.2 84
Short-wave-sensitive opsin 1 OPN1SW Tbio GPCR -1.90084 81.3 15
Protein C21orf2 C21orf2 Tbio Non-IDG -1.66840 37.4 95
Bardet-Biedl syndrome 7 protein BBS7 Tbio Non-IDG -1.02867 11.1 125
Dynein light chain 1, cytoplasmic DYNLL1 Tbio Non-IDG -2.65303 525.6 142
Centromere protein F CENPF Tbio Non-IDG -1.98596 103.0 180
Centrosomal protein of 290 kDa CEP290 Tbio Non-IDG -1.97186 101.3 125
Ras-related protein Rab-28 RAB28 Tbio Enzyme -1.12829 14.9 57
Retinitis pigmentosa 1-like 1 protein RP1L1 Tbio Non-IDG -1.19453 19.3 0