Development Level

Tbio 279 | 11,445
Tdark 71 | 6,588
Tchem 25 | 1,598
Tclin 16 | 613

Collection

RFA-RM-18-021 7 | 328
Kinase: IDG Consortium (Target... 5 | 125
GPCR: IDG Consortium (Targets) 4 | 126
Kinase: IDG Consortium (Comple... 2 | 37
GPCR: IDG Consortium (Complete... 1 | 25
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 34 | 979
preweaning lethality, incomple... 15 | 499
abnormal behavior 11 | 298
increased lean body mass 9 | 172
male infertility 8 | 123
decreased body weight 7 | 161
embryonic lethality prior to t... 7 | 278
decreased circulating glucose ... 6 | 126
increased fasted circulating g... 6 | 76
prenatal lethality prior to he... 6 | 87
decreased grip strength 5 | 116
hyperactivity 5 | 148
hypoactivity 5 | 132
increased circulating chloride... 5 | 41
increased circulating sodium l... 5 | 71
increased mean corpuscular hem... 5 | 96
abnormal embryo size 4 | 220
decreased circulating alkaline... 4 | 46
decreased circulating triglyce... 4 | 79
decreased prepulse inhibition 4 | 82
edema 4 | 59
impaired glucose tolerance 4 | 75
increased bone mineral content 4 | 108
increased circulating alkaline... 4 | 122
increased total body fat amoun... 4 | 134
abnormal heart morphology 3 | 162
decreased bone mineral content 3 | 151
decreased circulating amylase ... 3 | 28
decreased circulating insulin ... 3 | 76
decreased fasted circulating g... 3 | 65
decreased lean body mass 3 | 135
decreased startle reflex 3 | 75
decreased total body fat amoun... 3 | 207
embryonic growth retardation 3 | 106
enlarged heart 3 | 210
female infertility 3 | 60
increased blood urea nitrogen ... 3 | 48
increased mean corpuscular vol... 3 | 92
increased or absent threshold ... 3 | 101
increased startle reflex 3 | 112
limb grasping 3 | 41
short tibia 3 | 97
abnormal bone structure 2 | 187
abnormal coat appearance 2 | 31
abnormal embryo turning 2 | 31
abnormal eye morphology 2 | 68
abnormal humerus morphology 2 | 11
abnormal limb morphology 2 | 13
abnormal nail morphology 2 | 8
abnormal neural tube closure 2 | 46
abnormal pericardium morpholog... 2 | 26
abnormal retina morphology 2 | 71
abnormal sleep behavior 2 | 70
absent pinna reflex 2 | 23
cardiovascular system phenotyp... 2 | 36
decreased bone mineral density 2 | 126
decreased circulating choleste... 2 | 93
decreased circulating potassiu... 2 | 20
decreased circulating total pr... 2 | 49
decreased erythrocyte cell num... 2 | 62
decreased hemoglobin content 2 | 68
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular vol... 2 | 79
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
enlarged lymph nodes 2 | 37
hydrometra 2 | 53
impaired righting response 2 | 26
improved glucose tolerance 2 | 79
increased body weight 2 | 25
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
increased circulating glycerol... 2 | 9
increased grip strength 2 | 41
increased leukocyte cell numbe... 2 | 47
increased lymphocyte cell numb... 2 | 32
persistence of hyaloid vascula... 2 | 33
polycystic kidney 2 | 15
small superior vagus ganglion 2 | 74
stereotypic behavior 2 | 3
trunk curl 2 | 16
vertebral fusion 2 | 23
abnormal craniofacial morpholo... 1 | 33
abnormal ear morphology 1 | 9
abnormal retinal inner nuclear... 1 | 8
abnormal spleen morphology 1 | 55
abnormal whole-body plethysmog... 1 | 4
decreased body length 1 | 101
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
impaired pupillary reflex 1 | 26
increased blood uric acid leve... 1 | 5
increased bone mineral density 1 | 72
increased circulating amylase ... 1 | 25
increased circulating iron lev... 1 | 30
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
tremors 1 | 39

Disease

Carcinoma 290 | 11,493
osteosarcoma 164 | 7,950
ovarian cancer 158 | 8,520
ependymoma 153 | 4,679
medulloblastoma, large-cell 119 | 6,241
psoriasis 115 | 6,694
glioblastoma 109 | 5,792
atypical teratoid / rhabdoid tumor 106 | 5,112
Kidney cancer 85 | 2,613
group 3 medulloblastoma 84 | 4,104
Autosomal recessive predisposition 83 | 1,442
lung cancer 78 | 4,740
adult high grade glioma 77 | 3,801
Intellectual disability 75 | 1,016
Retinitis Pigmentosa 68 | 226
Breast cancer 67 | 3,578
chronic rhinosinusitis 61 | 512
primitive neuroectodermal tumor 60 | 3,035
Polydactyly 59 | 107
nasopharyngeal carcinoma 58 | 1,058
astrocytic glioma 56 | 2,597
Dull intelligence 55 | 645
Low intelligence 55 | 645
Mental Retardation 55 | 645
Mental deficiency 55 | 645
Poor school performance 55 | 645
malignant mesothelioma 55 | 3,232
Obesity 54 | 678
lung adenocarcinoma 54 | 2,716
lung carcinoma 54 | 2,843
Astrocytoma, Pilocytic 53 | 3,081
Nystagmus 50 | 317
oligodendroglioma 50 | 2,850
Ciliopathy 48 | 71
Pick disease 48 | 1,894
Nephronophthisis 46 | 80
Electroretinogram abnormal 44 | 95
Primary ciliary dyskinesia 44 | 76
intraductal papillary-mucinous adenoma (IPMA) 44 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 44 | 2,989
non-small cell lung cancer 44 | 2,890
Congenital hypoplasia of penis 43 | 176
Cancer 41 | 2,499
Cataract 41 | 297
pancreatic cancer 41 | 2,398
Lens Opacities 40 | 231
Hypogonadism 39 | 173
invasive ductal carcinoma 39 | 2,951
Abnormality of retinal pigmentation 38 | 111
Fundus dystrophy 38 | 83
Retinal pigment epithelial abnormality 38 | 111
tuberculosis 38 | 2,010
Retinal Degeneration 37 | 106
intraductal papillary-mucinous neoplasm (IPMN) 37 | 3,291
pituitary cancer 37 | 1,972
Bardet-Biedl syndrome 36 | 51
Broad flat nasal bridge 35 | 236
Nasal bridge wide 35 | 236
Optic Atrophy 35 | 242
Situs Inversus 35 | 65
group 4 medulloblastoma 35 | 1,855
subependymal giant cell astrocytoma 35 | 2,287
Joubert syndrome 34 | 66
Sensorineural Hearing Loss (disorder) 34 | 284
Short stature 34 | 531
Anteverted nostril 32 | 191
Cone dystrophy 32 | 71
Glaucoma 32 | 239
Night Blindness 32 | 101
Ciliary Motility Disorders 31 | 38
Photodysphoria 31 | 121
Photophobia 31 | 121
Cognitive delay 30 | 608
Difficulties with night vision 30 | 87
Global developmental delay 30 | 608
Mental and motor retardation 30 | 608
Schizophrenia 30 | 1,160
Blind Vision 29 | 111
interstitial cystitis 29 | 2,312
Blindness, Legal 28 | 110
Kartagener Syndrome 28 | 38
Keratoconus 27 | 113
Low Vision 27 | 174
Visual Impairment 27 | 174
ulcerative colitis 27 | 1,819
Conductive hearing loss 26 | 123
Hypertensive disease 26 | 292
Abnormality of the retinal vasculature 25 | 59
Asphyxiating thoracic dystrophy 25 | 44
Atypical scarring of skin 25 | 62
Congenital anomaly of testis 25 | 52
Hyperinsulinism 25 | 133
Leber congenital amaurosis 25 | 69
Night blindness, progressive 25 | 51
Ophthalmoplegia 25 | 106
colon cancer 25 | 1,478
posterior fossa group B ependymoma 25 | 416
Blindness 24 | 88
Liver cancer 24 | 604
Meckel syndrome 24 | 46

Tissue

Endocrine System 382 | 18,159
Female tissues 359 | 17,400
Skin and soft tissues 359 | 17,230
Digestive Tract 358 | 17,369
Male tissues 354 | 17,142
Nervous System 354 | 16,725
Respiratory system 345 | 16,393
Blood and immune system 344 | 16,909
Urinary Tract 344 | 16,678
Liver and Pancreas 340 | 16,750
Cardiovascular System 303 | 15,192

Target Family

Non-IDG 277 | 12,091
Enzyme 48 | 4,145
GPCR 22 | 408
Kinase 21 | 634
Ion Channel 10 | 344
Transcription Factor 6 | 1,400
Transporter 6 | 473
Epigenetic 1 | 242

Compartment GO Term

Ciliary part 391 | 391
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,237 | 12,237
Intracellular organelle 12,023 | 12,023
membrane-bounded organelle 11,130 | 11,130
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,340 | 10,340
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,561 | 7,561
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,972 | 3,972
non-membrane-bounded organelle 3,972 | 3,972
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,955 | 1,955
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,547 | 1,547
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,123 | 1,123
Nuclear outer membrane-endopla... 1,121 | 1,121
Nucleoplasm part 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,040 | 1,040
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 949 | 949
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 848 | 848
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Radial spoke head protein 3 homolog RSPH3 Tdark Non-IDG -1.14197 12.4 28
Prominin-1 PROM1 Tbio Non-IDG -3.30229 2035.0 351
Hematopoietic progenitor cell antigen CD34 CD34 Tbio Non-IDG -4.14691 13698.4 1952
Centrosomal protein of 131 kDa CEP131 Tbio Non-IDG -1.78486 61.9 82
B9 domain-containing protein 1 B9D1 Tdark Non-IDG -0.61316 3.72 43
Centrosomal protein of 41 kDa CEP41 Tdark Non-IDG -0.41185 3.40 46
Guanine nucleotide-binding protein G(q) subunit alpha GNAQ Tbio Non-IDG -2.73429 514.5 206
Bardet-Biedl syndrome 2 protein BBS2 Tbio Non-IDG -2.84516 693.9 69
Fibrocystin PKHD1 Tbio Non-IDG -1.71770 56.1 82
Solute carrier family 26 member 6 SLC26A6 Tbio Ion Channel -1.90119 75.2 94