Development Level

Tbio 62 | 11,445
Tdark 12 | 6,588
Tchem 8 | 1,598
Tclin 8 | 613

Collection

GPCR: IDG Consortium (Targets) 4 | 126
GPCR: IDG Consortium (Complete... 1 | 25
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 6 | 979
increased circulating chloride... 4 | 41
increased mean corpuscular hem... 4 | 96
preweaning lethality, incomple... 4 | 499
increased lean body mass 3 | 172
increased mean corpuscular vol... 3 | 92
increased total body fat amoun... 3 | 134
abnormal behavior 2 | 298
abnormal heart morphology 2 | 162
abnormal retina morphology 2 | 71
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating alkaline... 2 | 46
decreased circulating insulin ... 2 | 76
decreased circulating triglyce... 2 | 79
decreased grip strength 2 | 116
decreased lean body mass 2 | 135
decreased mean corpuscular vol... 2 | 79
enlarged heart 2 | 210
hyperactivity 2 | 148
impaired glucose tolerance 2 | 75
increased body weight 2 | 25
increased circulating alkaline... 2 | 122
abnormal behavioral response t... 1 | 66
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo development 1 | 7
abnormal embryo turning 1 | 31
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal nail morphology 1 | 8
abnormal pericardium morpholog... 1 | 26
abnormal response to tactile s... 1 | 17
abnormal retinal inner nuclear... 1 | 8
abnormal startle reflex 1 | 15
abnormal whole-body plethysmog... 1 | 4
decreased body length 1 | 101
decreased circulating amylase ... 1 | 28
decreased circulating glucose ... 1 | 126
decreased circulating total pr... 1 | 49
decreased fasted circulating g... 1 | 65
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased lactate dehydrogenas... 1 | 16
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
decreased respiratory quotient 1 | 16
decreased spleen weight 1 | 10
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
hypoactivity 1 | 132
increased blood urea nitrogen ... 1 | 48
increased blood uric acid leve... 1 | 5
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased cellular hemoglobin ... 1 | 1
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating potassiu... 1 | 29
increased fasted circulating g... 1 | 76
increased heart rate variabili... 1 | 7
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
macrophthalmia 1 | 2
prolonged PR interval 1 | 15
short tibia 1 | 97
thrombocytopenia 1 | 56
vertebral fusion 1 | 23

Disease

Carcinoma 70 | 11,493
ovarian cancer 38 | 8,520
osteosarcoma 33 | 7,950
Intellectual disability 32 | 1,016
ependymoma 28 | 4,679
medulloblastoma, large-cell 27 | 6,241
atypical teratoid / rhabdoid tumor 24 | 5,112
Autosomal recessive predisposition 22 | 1,442
Obesity 22 | 678
glioblastoma 22 | 5,792
Dull intelligence 21 | 645
Low intelligence 21 | 645
Mental Retardation 21 | 645
Mental deficiency 21 | 645
Poor school performance 21 | 645
psoriasis 21 | 6,694
Polydactyly 20 | 107
Retinitis Pigmentosa 20 | 226
Cone dystrophy 19 | 71
Fundus dystrophy 18 | 83
Nystagmus 18 | 317
Kidney cancer 17 | 2,613
group 3 medulloblastoma 17 | 4,104
lung cancer 17 | 4,740
Electroretinogram abnormal 16 | 95
Retinal Degeneration 16 | 106
adult high grade glioma 16 | 3,801
oligodendroglioma 16 | 2,850
astrocytic glioma 15 | 2,597
primitive neuroectodermal tumor 15 | 3,035
Astrocytoma, Pilocytic 14 | 3,081
Congenital hypoplasia of penis 14 | 176
Night Blindness 14 | 101
Photodysphoria 14 | 121
Photophobia 14 | 121
malignant mesothelioma 14 | 3,232
Abnormality of retinal pigmentation 13 | 111
Bardet-Biedl syndrome 13 | 51
Breast cancer 13 | 3,578
Broad flat nasal bridge 13 | 236
Cataract 13 | 297
Difficulties with night vision 13 | 87
Hypogonadism 13 | 173
Lens Opacities 13 | 231
Nasal bridge wide 13 | 236
Retinal pigment epithelial abnormality 13 | 111
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
lung carcinoma 13 | 2,843
Bardet-Biedl syndrome 1 12 | 22
Ciliopathy 12 | 71
Glaucoma 12 | 239
Nephronophthisis 12 | 80
Sensorineural Hearing Loss (disorder) 12 | 284
lung adenocarcinoma 12 | 2,716
Anteverted nostril 11 | 191
Blindness 11 | 88
Optic Atrophy 11 | 242
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
invasive ductal carcinoma 11 | 2,951
Blind Vision 10 | 111
Blindness, Legal 10 | 110
Joubert syndrome 10 | 66
Keratoconus 10 | 113
Meckel syndrome 10 | 46
interstitial cystitis 10 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
pancreatic cancer 10 | 2,398
Abnormality of the retinal vasculature 9 | 59
Atypical scarring of skin 9 | 62
Conductive hearing loss 9 | 123
Congenital anomaly of testis 9 | 52
Gastrointestinal Stromal Tumors 9 | 48
Hyperinsulinism 9 | 133
Night blindness, progressive 9 | 51
Ophthalmoplegia 9 | 106
Pick disease 9 | 1,894
pituitary cancer 9 | 1,972
subependymal giant cell astrocytoma 9 | 2,287
Hypertensive disease 8 | 292
Leber congenital amaurosis 8 | 69
Low Vision 8 | 174
Reduced visual acuity 8 | 63
Short stature 8 | 531
Ulnar polydactyly of fingers 8 | 47
Visual Impairment 8 | 174
posterior fossa group B ependymoma 8 | 416
Brachydactyly 7 | 156
Cognitive delay 7 | 608
Global developmental delay 7 | 608
Mental and motor retardation 7 | 608
Orbital separation excessive 7 | 244
Schizophrenia 7 | 1,160
diabetes mellitus 7 | 1,728
non-small cell lung cancer 7 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
tuberculosis 7 | 2,010
Cancer 6 | 2,499
Meckel-Gruber syndrome 6 | 13
Multicystic Dysplastic Kidney 6 | 52
spina bifida 6 | 1,074

Tissue

Endocrine System 84 | 18,159
Digestive Tract 81 | 17,369
Skin and soft tissues 79 | 17,230
Nervous System 78 | 16,725
Blood and immune system 75 | 16,909
Female tissues 75 | 17,400
Male tissues 74 | 17,142
Liver and Pancreas 73 | 16,750
Urinary Tract 72 | 16,678
Respiratory system 71 | 16,393
Cardiovascular System 64 | 15,192

Target Family

Non-IDG 45 | 12,091
GPCR 15 | 408
Enzyme 14 | 4,145
Ion Channel 8 | 344
Kinase 6 | 634
Transcription Factor 1 | 1,400
Transporter 1 | 473

Compartment GO Term

Ciliary membrane 90 | 90
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hedgehog-interacting protein HHIP Tbio Non-IDG -1.83526 65.4 193
Bardet-Biedl syndrome 4 protein BBS4 Tbio Non-IDG -1.53435 31.5 200
Transmembrane protein 17 TMEM17 Tbio Non-IDG 0.61 0.56 52
G-protein coupled receptor 157 GPR157 Tdark GPCR -0.04139 1.14 111
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
Retinal guanylyl cyclase 1 GUCY2D Tbio Kinase -2.20658 167.7 205
Guanylyl cyclase-activating protein 3 GUCA1C Tdark Enzyme 0.02 1.10 125
Rhodopsin kinase GRK7 Tchem Kinase -1.83396 45.0 180
Polycystin-2 PKD2 Tchem Ion Channel -2.63806 461.3 231
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha PDE6A Tclin Enzyme -1.29228 20.3 111