Development Level

Tbio 29 | 11,651
Tdark 8 | 6,593
Tchem 5 | 1,388

Collection

Kinase: IDG Consortium (Target... 2 | 125
RFA-RM-18-021 2 | 328
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 4 | 979
embryonic lethality prior to t... 2 | 278
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal humerus morphology 1 | 11
abnormal limb bud morphology 1 | 17
abnormal liver size 1 | 5
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal stomach morphology 1 | 10
decreased circulating alkaline... 1 | 46
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
enlarged lymph nodes 1 | 37
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating chloride... 1 | 41
increased circulating glycerol... 1 | 9
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
pale liver 1 | 6
pale yolk sac 1 | 25
pallor 1 | 34

Disease

Carcinoma 33 | 11,493
ependymoma 20 | 4,679
ovarian cancer 19 | 8,520
osteosarcoma 17 | 7,950
psoriasis 16 | 6,694
atypical teratoid / rhabdoid tumor 12 | 5,112
Polydactyly 11 | 107
glioblastoma 11 | 5,792
Ciliopathy 10 | 71
group 3 medulloblastoma 10 | 4,104
Autosomal recessive predisposition 9 | 1,442
Kidney cancer 9 | 2,613
chronic rhinosinusitis 9 | 512
lung cancer 9 | 4,740
malignant mesothelioma 9 | 3,232
medulloblastoma, large-cell 9 | 6,241
Nephronophthisis 8 | 80
Short stature 8 | 531
astrocytic glioma 8 | 2,597
oligodendroglioma 7 | 2,850
pancreatic cancer 7 | 2,398
primitive neuroectodermal tumor 7 | 3,035
Asphyxiating thoracic dystrophy 6 | 44
Astrocytoma, Pilocytic 6 | 3,081
Carney complex 6 | 25
Cleft Lip 6 | 141
Cognitive delay 6 | 608
Cryptorchidism 6 | 296
Gastrointestinal Stromal Tumors 6 | 48
Global developmental delay 6 | 608
Hydrocephalus 6 | 152
Intellectual disability 6 | 1,016
Mental and motor retardation 6 | 608
Obesity 6 | 678
adult high grade glioma 6 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
invasive ductal carcinoma 6 | 2,951
tuberculosis 6 | 2,010
Brachydactyly 5 | 156
Broad flat nasal bridge 5 | 236
Cancer 5 | 2,499
Congenital hypoplasia of penis 5 | 176
Dull intelligence 5 | 645
Hypertensive disease 5 | 292
Increase in blood pressure 5 | 119
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Nasal bridge wide 5 | 236
Orbital separation excessive 5 | 244
Poor school performance 5 | 645
Retinitis Pigmentosa 5 | 226
Ulnar polydactyly of fingers 5 | 47
active Crohn's disease 5 | 922
lung carcinoma 5 | 2,843
Abnormally small eyeball 4 | 97
Anteverted nostril 4 | 191
Breast cancer 4 | 3,578
Concave bridge of nose 4 | 195
Congenital Epicanthus 4 | 177
Decreased projection of midface 4 | 105
Decreased size of eyeball 4 | 97
Depressed nasal bridge 4 | 195
Depressed nasal root/bridge 4 | 195
Frontal bossing 4 | 157
Generalized osteopenia 4 | 99
Holoprosencephaly 4 | 56
Hypoplastic mandible condyle 4 | 275
Hypotrophic malar bone 4 | 129
Hypotrophic midface 4 | 105
Joubert syndrome 4 | 66
Malar flattening 4 | 129
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
Microphthalmos 4 | 100
Midface retrusion 4 | 105
Nevoid basal cell carcinoma syndrome 4 | 16
Nystagmus 4 | 317
Osteopenia 4 | 99
POLYDACTYLY, POSTAXIAL 4 | 13
Pick disease 4 | 1,894
Primary pigmented nodular adrenocortical disease 4 | 13
Senior-Loken syndrome 4 | 22
Small midface 4 | 105
cone-rod dystrophy 4 | 59
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
medulloblastoma 4 | 720
nasopharyngeal carcinoma 4 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pediatric high grade glioma 4 | 1,064
posterior fossa group B ependymoma 4 | 416
ulcerative colitis 4 | 1,819
Depressive disorder 3 | 409
astrocytoma 3 | 1,146
ductal carcinoma in situ 3 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
non-small cell lung cancer 3 | 2,890
pancreatic carcinoma 3 | 562
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,109

Tissue

Endocrine System 41 | 18,159
Male tissues 41 | 17,142
Digestive Tract 40 | 17,369
Female tissues 40 | 17,400
Liver and Pancreas 40 | 16,750
Nervous System 40 | 16,725
Respiratory system 40 | 16,393
Skin and soft tissues 40 | 17,230
Urinary Tract 40 | 16,678
Blood and immune system 39 | 16,909
Cardiovascular System 38 | 15,192

Target Family

Non-IDG 25 | 12,091
Enzyme 8 | 4,145
Kinase 5 | 634
Transcription Factor 4 | 1,400

Compartment GO Term

Ciliary base 42 | 42
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tetratricopeptide repeat protein 30A TTC30A Tdark Non-IDG 0.60 0.00000 57
cAMP-dependent protein kinase catalytic subunit alpha PRKACA Tchem Kinase -1.09531 11.7 331
Intraflagellar transport protein 27 homolog IFT27 Tbio Enzyme -1.24496 16.5 91
Suppressor of fused homolog SUFU Tbio Non-IDG -2.33544 208.6 168
Rab-like protein 2B RABL2B Tbio Enzyme -0.79443 2.67 32
MAPK/MAK/MRK overlapping kinase MOK Tbio Kinase -1.78079 60.3 312
Zinc finger protein GLI2 GLI2 Tchem Transcription Factor -2.58228 355.0 196
Transcriptional activator GLI3 GLI3 Tbio Transcription Factor -3.19296 1388.8 190
ADP-ribosylation factor-like protein 13B ARL13B Tbio Enzyme -1.51205 32.9 74
Zinc finger protein GLI1 GLI1 Tchem Transcription Factor -3.04303 1054.8 450