Development Level

Tbio 72 | 11,445
Tdark 16 | 6,588
Tchem 5 | 1,598

Collection

Kinase: IDG Consortium (Target... 3 | 125
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 11 | 979
preweaning lethality, incomple... 5 | 499
abnormal behavior 4 | 298
embryonic lethality prior to t... 4 | 278
male infertility 4 | 123
female infertility 3 | 60
hypoactivity 3 | 132
increased fasted circulating g... 3 | 76
abnormal embryo size 2 | 220
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased grip strength 2 | 116
embryonic growth retardation 2 | 106
impaired glucose tolerance 2 | 75
increased circulating alkaline... 2 | 122
increased lymphocyte cell numb... 2 | 32
increased total body fat amoun... 2 | 134
prenatal lethality prior to he... 2 | 87
abnormal behavioral response t... 1 | 66
abnormal brain morphology 1 | 13
abnormal embryo turning 1 | 31
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal nail morphology 1 | 8
abnormal pancreas morphology 1 | 13
abnormal pericardium morpholog... 1 | 26
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
convulsive seizures 1 | 13
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased coping response 1 | 8
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased respiratory quotient 1 | 16
decreased spleen weight 1 | 10
edema 1 | 59
enlarged heart 1 | 210
hydroencephaly 1 | 14
hydrometra 1 | 53
hyperactivity 1 | 148
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased grip strength 1 | 41
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
persistence of hyaloid vascula... 1 | 33
short tibia 1 | 97
shortened RR interval 1 | 17
small superior vagus ganglion 1 | 74
small testis 1 | 58
thrombocytopenia 1 | 56

Disease

Carcinoma 69 | 11,493
ovarian cancer 48 | 8,520
osteosarcoma 46 | 7,950
ependymoma 38 | 4,679
medulloblastoma, large-cell 34 | 6,241
atypical teratoid / rhabdoid tumor 30 | 5,112
glioblastoma 29 | 5,792
Polydactyly 25 | 107
psoriasis 25 | 6,694
Intellectual disability 24 | 1,016
group 3 medulloblastoma 24 | 4,104
Kidney cancer 23 | 2,613
Autosomal recessive predisposition 22 | 1,442
Ciliopathy 21 | 71
Retinitis Pigmentosa 20 | 226
Breast cancer 19 | 3,578
Pick disease 19 | 1,894
adult high grade glioma 19 | 3,801
lung cancer 19 | 4,740
primitive neuroectodermal tumor 19 | 3,035
Dull intelligence 18 | 645
Low intelligence 18 | 645
Mental Retardation 18 | 645
Mental deficiency 18 | 645
Poor school performance 18 | 645
Nystagmus 17 | 317
Obesity 17 | 678
chronic rhinosinusitis 17 | 512
malignant mesothelioma 17 | 3,232
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
lung carcinoma 16 | 2,843
Congenital hypoplasia of penis 15 | 176
Joubert syndrome 14 | 66
Nephronophthisis 14 | 80
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
non-small cell lung cancer 14 | 2,890
Astrocytoma, Pilocytic 13 | 3,081
Bardet-Biedl syndrome 13 | 51
Electroretinogram abnormal 13 | 95
astrocytic glioma 13 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
oligodendroglioma 13 | 2,850
Cerebellar Ataxia 12 | 304
Hypogonadism 12 | 173
Brachydactyly 11 | 156
Cone dystrophy 11 | 71
Fundus dystrophy 11 | 83
Optic Atrophy 11 | 242
invasive ductal carcinoma 11 | 2,951
lung adenocarcinoma 11 | 2,716
Asphyxiating thoracic dystrophy 10 | 44
Cataract 10 | 297
Cognitive delay 10 | 608
Global developmental delay 10 | 608
Lens Opacities 10 | 231
Mental and motor retardation 10 | 608
Multicystic Dysplastic Kidney 10 | 52
Ulnar polydactyly of fingers 10 | 47
tuberculosis 10 | 2,010
Anteverted nostril 9 | 191
Broad flat nasal bridge 9 | 236
Nasal bridge wide 9 | 236
Short stature 9 | 531
interstitial cystitis 9 | 2,312
pituitary cancer 9 | 1,972
Abnormality of retinal pigmentation 8 | 111
Bardet-Biedl syndrome 1 8 | 22
Blind Vision 8 | 111
Cleft Palate 8 | 271
Cryptorchidism 8 | 296
Feeding difficulties in infancy 8 | 175
Hypertensive disease 8 | 292
Increase in blood pressure 8 | 119
Muscle hypotonia 8 | 571
Photodysphoria 8 | 121
Photophobia 8 | 121
Retinal Degeneration 8 | 106
Retinal pigment epithelial abnormality 8 | 111
breast carcinoma 8 | 1,638
cone-rod dystrophy 8 | 59
diabetes mellitus 8 | 1,728
group 4 medulloblastoma 8 | 1,855
nasopharyngeal carcinoma 8 | 1,058
Blindness, Legal 7 | 110
Conductive hearing loss 7 | 123
Congenital anomaly of testis 7 | 52
Congenital hypoplasia of ovary 7 | 30
Glaucoma 7 | 239
Hydrocephalus 7 | 152
Hyperinsulinism 7 | 133
Hypoplastic ovary 7 | 30
Keratoconus 7 | 113
Long face 7 | 71
Ophthalmoplegia 7 | 106
Polydactyly of toes 7 | 12
Sensorineural Hearing Loss (disorder) 7 | 284
Small head 7 | 374
Uranostaphyloschisis 7 | 167
active Crohn's disease 7 | 922
ductal carcinoma in situ 7 | 1,745

Tissue

Endocrine System 93 | 18,159
Female tissues 93 | 17,400
Male tissues 93 | 17,142
Skin and soft tissues 93 | 17,230
Respiratory system 92 | 16,393
Digestive Tract 91 | 17,369
Liver and Pancreas 91 | 16,750
Nervous System 91 | 16,725
Urinary Tract 91 | 16,678
Blood and immune system 90 | 16,909
Cardiovascular System 87 | 15,192

Target Family

Non-IDG 74 | 12,091
Enzyme 11 | 4,145
Kinase 5 | 634
Ion Channel 2 | 344
Epigenetic 1 | 242

Compartment GO Term

Ciliary basal body 93 | 93
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Growth arrest-specific protein 8 GAS8 Tbio Non-IDG -1.20822 17.3 102
Bardet-Biedl syndrome 4 protein BBS4 Tbio Non-IDG -1.53435 31.5 200
Rotatin RTTN Tbio Non-IDG -0.87856 9.51 13
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.31837 20.5 59
Sodium channel and clathrin linker 1 SCLT1 Tdark Non-IDG -0.50820 2.61 97
Polycystin-2 PKD2 Tchem Ion Channel -2.63806 461.3 231
TOG array regulator of axonemal microtubules protein 1 TOGARAM1 Tdark Non-IDG -0.23045 1.13 9
Disheveled-associated activator of morphogenesis 1 DAAM1 Tbio Non-IDG -1.45166 30.8 269
Bardet-Biedl syndrome 2 protein BBS2 Tbio Non-IDG -2.84516 693.9 69
B9 domain-containing protein 1 B9D1 Tdark Non-IDG -0.61316 3.72 43