Development Level

Tbio 23 | 11,445
Tchem 12 | 1,598
Tclin 5 | 613

IMPC Phenotype

increased circulating choleste... 3 | 66
preweaning lethality, complete... 3 | 979
abnormal tooth morphology 2 | 24
increased circulating free fat... 2 | 20
increased circulating triglyce... 2 | 42
abnormal skin condition 1 | 6
absent optic nerve 1 | 2
cardiovascular system phenotyp... 1 | 36
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 11
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased circulating unsatura... 1 | 2
decreased erythrocyte cell num... 1 | 62
decreased heart rate 1 | 18
decreased lactate dehydrogenas... 1 | 16
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged spleen 1 | 41
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating iron lev... 1 | 30
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased red blood cell distr... 1 | 34
increased total body fat amoun... 1 | 134
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38

Disease

Atherosclerosis 28 | 291
Lipid metabolism disorder 28 | 114
Coronary artery disease 27 | 268
Carcinoma 26 | 11,493
diabetes mellitus 26 | 1,728
Obesity 23 | 678
psoriasis 18 | 6,694
ovarian cancer 16 | 8,520
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
Kidney disease 13 | 430
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
Autosomal recessive predisposition 12 | 1,442
Cardiovascular system disease 12 | 246
Hyperlipidemia 12 | 43
Hypertension 12 | 396
invasive ductal carcinoma 12 | 2,951
osteosarcoma 12 | 7,950
Cancer 10 | 2,499
Fatty liver disease 10 | 103
Hypercholesterolemia 10 | 44
Hypercholesterolemia, Familial 10 | 23
Hyperglycemia 10 | 137
Hypertensive disease 10 | 292
glioblastoma 10 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
lung cancer 10 | 4,740
Breast cancer 9 | 3,578
Cerebrovascular disease 9 | 238
Heart disease 9 | 306
Hyperlipoproteinemia Type II 9 | 12
Pancreatitis 9 | 123
ductal carcinoma in situ 9 | 1,745
lung adenocarcinoma 9 | 2,716
non-small cell lung cancer 9 | 2,890
pancreatic cancer 9 | 2,398
Hypertriglyceridemia 8 | 17
Liver Cirrhosis, Experimental 8 | 769
Vascular disease 8 | 319
malignant mesothelioma 8 | 3,232
medulloblastoma, large-cell 8 | 6,241
Arcus Senilis 7 | 11
Cardiovascular Diseases 7 | 59
Dyslipidemias 7 | 27
Hyperlipidemias 7 | 17
Liver disease 7 | 237
Serum cholesterol raised 7 | 22
Steatorrhea 7 | 34
cystic fibrosis 7 | 1,696
Alzheimer's disease 6 | 658
atypical teratoid / rhabdoid tumor 6 | 5,112
breast carcinoma 6 | 1,638
group 3 medulloblastoma 6 | 4,104
lung carcinoma 6 | 2,843
Amyloidosis 5 | 67
Cholestasis 5 | 155
Coronary Disease 5 | 25
Coronary heart disease 5 | 16
Diarrhea 5 | 253
Fatty Liver 5 | 70
Hepatitis C 5 | 94
Hyperinsulinism 5 | 133
Hypothyroidism 5 | 122
Kidney cancer 5 | 2,613
Metabolic syndrome X 5 | 52
Myocardial Infarction 5 | 151
Proteinuria 5 | 144
Schizophrenia 5 | 1,160
Type 2 diabetes mellitus 5 | 272
Xanthomatosis 5 | 12
ependymoma 5 | 4,679
oligodendroglioma 5 | 2,850
subependymal giant cell astrocytoma 5 | 2,287
tuberculosis 5 | 2,010
Anemia 4 | 365
Arthritis 4 | 290
Astrocytoma, Pilocytic 4 | 3,081
Brain disease 4 | 96
Chemical and Drug Induced Liver Injury 4 | 195
Diabetes Mellitus, Non-Insulin-Dependent 4 | 145
Exocrine pancreatic insufficiency 4 | 32
Familial hypercholesterolemia - homozygous 4 | 7
Familial hyperlipidemia 4 | 6
Heart failure 4 | 162
Hypercholesterolemia, Autosomal Dominant, Type B 4 | 5
Hyperlipoproteinemia Type IIa 4 | 11
Hypertriglyceridemia result 4 | 37
Hypoglycemia 4 | 152
Increase in blood pressure 4 | 119
Kidney Failure 4 | 111
Low density lipoprotein increased 4 | 8
Macular degeneration 4 | 65
Multiple myeloma 4 | 1,332
Renal Insufficiency 4 | 90
Sitosterolemia 4 | 9
Splenomegaly 4 | 190
adult high grade glioma 4 | 3,801
astrocytic glioma 4 | 2,597
interstitial cystitis 4 | 2,312
pediatric high grade glioma 3 | 1,064

Tissue

Digestive Tract 40 | 17,369
Endocrine System 40 | 18,159
Female tissues 40 | 17,400
Liver and Pancreas 39 | 16,750
Skin and soft tissues 38 | 17,230
Urinary Tract 37 | 16,678
Male tissues 36 | 17,142
Blood and immune system 35 | 16,909
Nervous System 34 | 16,725
Respiratory system 34 | 16,393
Cardiovascular System 30 | 15,192

Target Family

Non-IDG 27 | 12,091
Enzyme 10 | 4,145
Transporter 2 | 473
Kinase 1 | 634

Compartment GO Term

Chylomicron 40 | 40
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTP-binding protein SAR1b SAR1B Tbio Enzyme -1.91051 79.7 184
CD2-associated protein CD2AP Tbio Non-IDG -3.44533 2735.9 82
Niemann-Pick C1-like protein 1 NPC1L1 Tclin Non-IDG -2.33312 222.7 139
Scavenger receptor class B member 1 SCARB1 Tchem Non-IDG -2.93920 915.7 378
Serum albumin ALB Tchem Non-IDG -5.01233 98804.9 2101
Fatty acid-binding protein, intestinal FABP2 Tchem Non-IDG -2.54500 414.9 369
Apolipoprotein B receptor APOBR Tbio Non-IDG -1.00933 12.4 135
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 GPIHBP1 Tbio Non-IDG -1.82315 79.6 104
Apolipoprotein A-V APOA5 Tbio Non-IDG -2.58826 425.0 481
Apolipoprotein C-I APOC1 Tbio Non-IDG -2.39715 256.4 274