Development Level

Tbio 690 | 10,625
Tchem 160 | 1,890
Tdark 106 | 7,003
Tclin 43 | 602

IMPC Term

preweaning lethality, complete... 80 | 633
preweaning lethality, incomple... 27 | 260
embryonic lethality prior to o... 26 | 148
embryonic lethality prior to t... 24 | 187
abnormal behavior 15 | 226
decreased total body fat amoun... 15 | 186
decreased lean body mass 13 | 195
abnormal embryo size 12 | 112
decreased body weight 12 | 174
decreased body length 11 | 108
increased grip strength 10 | 83
increased mean corpuscular hem... 10 | 93
abnormal retina morphology 9 | 100
increased circulating sodium l... 9 | 71
male infertility 9 | 62
decreased bone mineral density 8 | 126
enlarged heart 8 | 111
increased circulating alkaline... 8 | 119
increased lean body mass 8 | 107
increased mean corpuscular vol... 8 | 91
prenatal lethality prior to he... 8 | 64
abnormal bone structure 7 | 131
decreased bone mineral content 7 | 157
hydrops fetalis 7 | 22
hyperactivity 7 | 108
hypoactivity 7 | 89
increased bone mineral content 7 | 92
increased bone mineral density 7 | 52
increased or absent threshold ... 7 | 128
decreased caudal vertebrae num... 6 | 49
decreased circulating serum al... 6 | 79
decreased grip strength 6 | 123
female infertility 6 | 34
increased circulating HDL chol... 6 | 63
increased sacral vertebrae num... 6 | 62
small testis 6 | 37
thrombocytopenia 6 | 46
abnormal coat/hair pigmentatio... 5 | 54
abnormal eye morphology 5 | 38
abnormal gait 5 | 51
abnormal lens morphology 5 | 73
cataract 5 | 26
decreased circulating choleste... 5 | 85
decreased circulating glucose ... 5 | 121
decreased eosinophil cell numb... 5 | 41
decreased leukocyte cell numbe... 5 | 54
decreased mean corpuscular hem... 5 | 34
decreased mean corpuscular vol... 5 | 50
decreased rib number 5 | 59
increased circulating choleste... 5 | 53
increased circulating triglyce... 5 | 24
increased heart weight 5 | 37
increased mean platelet volume 5 | 19
short tibia 5 | 82
abnormal cornea morphology 4 | 24
abnormal heart morphology 4 | 51
abnormal neural tube closure 4 | 37
abnormal seminal vesicle morph... 4 | 47
abnormal spleen morphology 4 | 36
corneal opacity 4 | 25
decreased basophil cell number 4 | 11
decreased circulating LDL chol... 4 | 37
decreased circulating alanine ... 4 | 53
decreased circulating chloride... 4 | 32
decreased effector memory CD8-... 4 | 24
decreased fasted circulating g... 4 | 49
decreased heart weight 4 | 44
decreased hemoglobin content 4 | 53
decreased lumbar vertebrae num... 4 | 62
decreased prepulse inhibition 4 | 52
embryonic growth retardation 4 | 28
increased circulating chloride... 4 | 43
increased fasted circulating g... 4 | 68
abnormal behavioral response t... 3 | 52
abnormal coat appearance 3 | 25
abnormal epididymis morphology 3 | 31
abnormal retinal pigmentation 3 | 61
abnormal rib morphology 3 | 28
abnormal startle reflex 3 | 14
abnormal testis morphology 3 | 30
abnormal tooth morphology 3 | 24
cardiovascular system phenotyp... 3 | 35
decreased Ly6C high monocyte n... 3 | 18
decreased blood urea nitrogen ... 3 | 31
decreased circulating HDL chol... 3 | 77
decreased circulating alkaline... 3 | 41
decreased circulating free fat... 3 | 39
decreased circulating fructosa... 3 | 31
decreased circulating triglyce... 3 | 83
improved glucose tolerance 3 | 56
increased CD4-positive, CD25-p... 3 | 18
increased blood urea nitrogen ... 3 | 44
increased body weight 3 | 42
increased circulating iron lev... 3 | 25
increased effector memory CD4-... 3 | 15
increased hematocrit 3 | 36
increased mean corpuscular hem... 3 | 25
shortened RR interval 3 | 19
tremors 3 | 34
vertebral fusion 3 | 23

Disease

ovarian cancer 567 | 8,492
osteosarcoma 496 | 7,933
medulloblastoma, large-cell 429 | 6,234
psoriasis 417 | 6,685
lung cancer 374 | 4,473
glioblastoma 372 | 5,572
Cancer 354 | 2,346
atypical teratoid / rhabdoid tumor 283 | 4,369
malignant mesothelioma 275 | 3,163
Breast cancer 271 | 3,099
primitive neuroectodermal tumor 269 | 3,031
non-small cell lung cancer 228 | 2,798
group 3 medulloblastoma 222 | 2,254
pediatric high grade glioma 218 | 2,712
intraductal papillary-mucinous neoplasm (IPMN) 217 | 3,289
intraductal papillary-mucinous carcinoma (IPMC) 203 | 2,988
lung adenocarcinoma 203 | 2,714
invasive ductal carcinoma 194 | 2,950
oligodendroglioma 174 | 2,849
Carcinoma 170 | 2,147
adrenocortical carcinoma 148 | 1,427
ependymoma 146 | 2,514
ductal carcinoma in situ 138 | 1,745
colon cancer 136 | 1,475
intraductal papillary-mucinous adenoma (IPMA) 130 | 2,956
pancreatic cancer 128 | 2,300
Multiple myeloma 123 | 1,328
breast carcinoma 120 | 1,614
astrocytic glioma 116 | 2,241
astrocytoma 114 | 1,493
pilocytic astrocytoma 112 | 3,086
diabetes mellitus 110 | 1,663
group 4 medulloblastoma 109 | 1,875
sonic hedgehog group medulloblastoma 107 | 1,482
ulcerative colitis 107 | 2,087
posterior fossa group A ependymoma 105 | 1,511
subependymal giant cell astrocytoma 104 | 2,287
pituitary cancer 101 | 1,972
Rheumatoid Arthritis 100 | 1,171
Waldenstrons macroglobulinemia 96 | 765
Pick disease 95 | 1,893
nasopharyngeal carcinoma 95 | 1,056
lung carcinoma 91 | 2,844
Endometriosis 88 | 535
acute quadriplegic myopathy 88 | 1,157
adult high grade glioma 88 | 2,148
dermatomyositis 88 | 967
pancreatic ductal adenocarcinoma liver metastasis 86 | 1,795
medulloblastoma 85 | 1,524
atypical teratoid/rhabdoid tumor 84 | 1,095
juvenile dermatomyositis 81 | 1,189
interstitial cystitis 80 | 2,299
Intellectual disability 74 | 573
Mammary Neoplasms 74 | 410
Atopic dermatitis 70 | 944
tuberculosis 70 | 1,563
acute myeloid leukemia 64 | 785
Prostatic Neoplasms 62 | 471
primary Sjogren syndrome 59 | 789
cystic fibrosis 56 | 1,670
Alzheimer's disease 53 | 644
non primary Sjogren syndrome sicca 53 | 840
Obesity 52 | 616
primary pancreatic ductal adenocarcinoma 52 | 1,271
IGA Glomerulonephritis 51 | 454
gastric carcinoma 49 | 832
Stomach Neoplasms 47 | 282
hepatocellular carcinoma 47 | 550
spina bifida 47 | 1,064
posterior fossa group B ependymoma 45 | 1,530
tuberculosis and treatment for 6 months 45 | 686
pancreatic carcinoma 43 | 567
cutaneous lupus erythematosus 42 | 1,056
gastric cancer 42 | 436
Liver carcinoma 41 | 217
Lung Neoplasms 41 | 171
Adenoma 40 | 165
progressive supranuclear palsy 40 | 674
Down syndrome 39 | 548
Peripheral Neuropathy 38 | 303
aldosterone-producing adenoma 38 | 664
non-small cell lung carcinoma 38 | 413
Kidney disease 37 | 397
esophageal adenocarcinoma 37 | 737
inflammatory breast cancer 37 | 404
Male infertility 36 | 170
Amyotrophic Lateral Sclerosis 35 | 432
Neurodegenerative disease 35 | 383
Heart disease 34 | 279
Infertility 34 | 163
Melanoma 34 | 261
Colorectal Neoplasms 33 | 217
Fanconi's anemia 33 | 50
Adenoid Cystic Carcinoma 32 | 99
Anemia 32 | 252
Schizophrenia 32 | 503
Bladder Neoplasm 31 | 109
Asthma 30 | 349
Vascular disease 30 | 281
active Crohn's disease 29 | 918

Tissue

Female tissues 991 | 18,647
Digestive Tract 983 | 18,473
Male tissues 983 | 17,969
Blood and immune system 982 | 17,995
Endocrine System 982 | 18,512
Liver and Pancreas 980 | 18,136
Nervous System 980 | 18,561
Urinary Tract 977 | 18,444
Cardiovascular System 971 | 17,958
Skin and soft tissues 961 | 18,115
Respiratory system 956 | 17,484

Target Family

Non-IDG 524 | 11,969
Enzyme 163 | 4,146
Transcription Factor 154 | 1,400
Epigenetic 94 | 242
Kinase 32 | 634
TF/Epigenetic 15 | 38
Nuclear Receptor 14 | 48
Transporter 2 | 473
Ion Channel 1 | 341

Compartment GO Term

Chromosome 999 | 999
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA polymerase delta catalytic subunit POLD1 Tclin Enzyme -2.02098 96.6 198
Lysyl oxidase homolog 2 LOXL2 Tbio Enzyme -2.17984 142.0 237
Bromodomain adjacent to zinc finger domain protein 2A BAZ2A Tchem TF/Epigenetic -2.05410 110.9 33
Protein LLP homolog LLPH Tdark Non-IDG -0.50515 3.00 49
DNA replication complex GINS protein SLD5 GINS4 Tdark Non-IDG -1.25647 17.0 45
Chromosome transmission fidelity protein 18 homolog CHTF18 Tbio Non-IDG -1.50198 33.7 113
Protein C-ets-2 ETS2 Tbio Transcription Factor -2.39443 244.9 192
Small kinetochore-associated protein KNSTRN Tbio Non-IDG -1.24054 16.5 27
Zinc finger protein 330 ZNF330 Tdark Non-IDG -0.41913 3.06 15
Centromere protein K CENPK Tbio Non-IDG -1.21037 16.5 109