Development Level

Tbio 762 | 11,651
Tchem 133 | 1,388
Tdark 99 | 6,593
Tclin 45 | 612

Collection

Kinase: IDG Consortium (Comple... 2 | 37

IMPC Phenotype

preweaning lethality, complete... 131 | 979
preweaning lethality, incomple... 45 | 499
embryonic lethality prior to t... 39 | 278
embryonic lethality prior to o... 38 | 239
abnormal behavior 22 | 298
abnormal embryo size 22 | 220
abnormal bone structure 15 | 187
decreased total body fat amoun... 15 | 207
increased startle reflex 15 | 112
male infertility 15 | 123
decreased vertical activity 14 | 208
decreased body weight 13 | 161
enlarged heart 13 | 210
decreased bone mineral density 12 | 126
embryonic growth retardation 12 | 106
increased mean corpuscular hem... 12 | 96
increased circulating HDL chol... 11 | 80
abnormal heart morphology 10 | 162
abnormal seminal vesicle morph... 10 | 114
female infertility 10 | 60
hyperactivity 10 | 148
impaired glucose tolerance 10 | 75
increased circulating alkaline... 10 | 122
increased lean body mass 10 | 172
prenatal lethality prior to he... 10 | 87
cataract 9 | 92
decreased bone mineral content 9 | 151
decreased lean body mass 9 | 135
increased bone mineral content 9 | 108
abnormal lens morphology 8 | 81
decreased body length 8 | 101
decreased prepulse inhibition 8 | 82
increased bone mineral density 8 | 72
increased mean corpuscular vol... 8 | 92
increased total body fat amoun... 8 | 134
abnormal gait 7 | 69
abnormal retina morphology 7 | 71
decreased circulating choleste... 7 | 93
decreased circulating glucose ... 7 | 126
decreased circulating serum al... 7 | 82
edema 7 | 59
hypoactivity 7 | 132
increased circulating choleste... 7 | 66
short tibia 7 | 97
small testis 7 | 58
thrombocytopenia 7 | 56
decreased caudal vertebrae num... 6 | 53
decreased circulating alanine ... 6 | 47
decreased circulating total pr... 6 | 49
decreased erythrocyte cell num... 6 | 62
increased circulating sodium l... 6 | 71
increased circulating triglyce... 6 | 42
increased mean platelet volume 6 | 45
abnormal embryo turning 5 | 31
cardiovascular system phenotyp... 5 | 36
decreased blood urea nitrogen ... 5 | 51
decreased circulating LDL chol... 5 | 38
decreased grip strength 5 | 116
decreased leukocyte cell numbe... 5 | 73
improved glucose tolerance 5 | 79
increased fasted circulating g... 5 | 76
increased heart weight 5 | 62
increased neutrophil cell numb... 5 | 46
small spleen 5 | 19
vertebral transformation 5 | 12
abnormal behavioral response t... 4 | 66
abnormal bone mineralization 4 | 38
abnormal coat-hair pigmentatio... 4 | 64
abnormal cornea morphology 4 | 31
abnormal eye morphology 4 | 68
abnormal neural tube closure 4 | 46
abnormal retinal blood vessel ... 4 | 26
abnormal spleen morphology 4 | 55
abnormal tail morphology 4 | 25
corneal opacity 4 | 32
decreased basophil cell number 4 | 16
decreased circulating HDL chol... 4 | 68
decreased circulating iron lev... 4 | 32
decreased circulating triglyce... 4 | 79
decreased fasted circulating g... 4 | 65
decreased heart left ventricle... 4 | 28
decreased hematocrit 4 | 46
decreased lymphocyte cell numb... 4 | 83
decreased mean corpuscular vol... 4 | 79
hemorrhage 4 | 23
increased circulating chloride... 4 | 41
increased hemoglobin content 4 | 45
increased monocyte cell number 4 | 63
increased or absent threshold ... 4 | 101
prolonged ST segment 4 | 36
shortened RR interval 4 | 17
abnormal epididymis morphology 3 | 42
abnormal lung morphology 3 | 26
abnormal retinal vasculature m... 3 | 27
anophthalmia 3 | 33
decreased circulating insulin ... 3 | 76
decreased hemoglobin content 3 | 68
increased body weight 3 | 25
increased circulating calcium ... 3 | 34
microphthalmia 3 | 26

Disease

Carcinoma 692 | 11,493
ovarian cancer 583 | 8,520
osteosarcoma 508 | 7,950
medulloblastoma, large-cell 449 | 6,241
psoriasis 435 | 6,694
glioblastoma 402 | 5,792
lung cancer 399 | 4,740
Cancer 381 | 2,499
group 3 medulloblastoma 375 | 4,104
atypical teratoid / rhabdoid tumor 357 | 5,112
Breast cancer 321 | 3,578
malignant mesothelioma 296 | 3,232
primitive neuroectodermal tumor 279 | 3,035
ependymoma 263 | 4,679
non-small cell lung cancer 242 | 2,890
adult high grade glioma 226 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 225 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 213 | 2,989
lung adenocarcinoma 210 | 2,716
Kidney cancer 209 | 2,613
invasive ductal carcinoma 204 | 2,951
oligodendroglioma 181 | 2,850
adrenocortical carcinoma 157 | 1,428
ductal carcinoma in situ 144 | 1,745
pancreatic cancer 143 | 2,398
astrocytic glioma 138 | 2,597
colon cancer 138 | 1,478
breast carcinoma 135 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 135 | 2,955
Intellectual disability 128 | 1,016
Multiple myeloma 124 | 1,332
diabetes mellitus 122 | 1,728
Astrocytoma, Pilocytic 118 | 3,081
subependymal giant cell astrocytoma 111 | 2,287
astrocytoma 106 | 1,146
pituitary cancer 105 | 1,972
ulcerative colitis 104 | 1,819
Rheumatoid arthritis 102 | 1,191
Schizophrenia 102 | 1,160
group 4 medulloblastoma 102 | 1,855
Pick disease 100 | 1,894
Short stature 100 | 531
Waldenstrons macroglobulinemia 96 | 765
tuberculosis 96 | 2,010
Endometriosis 94 | 540
lung carcinoma 94 | 2,843
nasopharyngeal carcinoma 94 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 93 | 1,962
pediatric high grade glioma 92 | 1,064
acute quadriplegic myopathy 90 | 1,158
dermatomyositis 89 | 966
interstitial cystitis 87 | 2,312
Autosomal recessive predisposition 86 | 1,442
juvenile dermatomyositis 86 | 1,187
Dull intelligence 85 | 645
Low intelligence 85 | 645
Mental Retardation 85 | 645
Mental deficiency 85 | 645
Poor school performance 85 | 645
Cognitive delay 83 | 608
Global developmental delay 83 | 608
Mental and motor retardation 83 | 608
Breast Neoplasms 82 | 445
Mammary Neoplasms 80 | 425
Atopic dermatitis 74 | 952
Small head 74 | 374
Epilepsy 70 | 792
Cryptorchidism 68 | 296
Prostatic Neoplasms 65 | 495
Seizures 64 | 596
acute myeloid leukemia 62 | 783
Obesity 61 | 678
Alzheimer's disease 60 | 658
Muscle hypotonia 60 | 571
non primary Sjogren syndrome sicca 59 | 891
primary Sjogren syndrome 59 | 735
cystic fibrosis 58 | 1,696
medulloblastoma 53 | 720
Liver cancer 52 | 604
Melanoma 52 | 711
Bipolar Disorder 51 | 666
Hypoplastic mandible condyle 51 | 275
Mandibular hypoplasia 51 | 275
Micrognathism 51 | 275
Stomach Neoplasms 51 | 300
Failure to gain weight 50 | 365
Pediatric failure to thrive 50 | 365
hepatocellular carcinoma 50 | 547
Depressive disorder 49 | 409
Lung Neoplasms 49 | 232
spina bifida 49 | 1,074
primary pancreatic ductal adenocarcinoma 48 | 1,109
Blepharoptosis 47 | 231
Male infertility 46 | 206
Anemia 45 | 365
Strabismus 45 | 270
gastric carcinoma 45 | 807
gastric cancer 44 | 459
Fetal Growth Retardation 43 | 189
Infant, Small for Gestational Age 43 | 176

Tissue

Endocrine System 1,019 | 18,159
Digestive Tract 999 | 17,369
Female tissues 995 | 17,400
Skin and soft tissues 991 | 17,230
Male tissues 990 | 17,142
Blood and immune system 987 | 16,909
Liver and Pancreas 978 | 16,750
Urinary Tract 973 | 16,678
Nervous System 972 | 16,725
Respiratory system 969 | 16,393
Cardiovascular System 932 | 15,192

Target Family

Non-IDG 542 | 12,091
Enzyme 175 | 4,145
Transcription Factor 161 | 1,400
Epigenetic 98 | 242
Kinase 31 | 634
Nuclear Receptor 16 | 48
TF/Epigenetic 13 | 38
Transporter 2 | 473
Ion Channel 1 | 344

Compartment GO Term

Chromosome 1,039 | 1,039
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
COP9 signalosome complex subunit 9 COPS9 Tbio Non-IDG 0.21 0.92 14
Amelogenin, X isoform AMELX Tbio Non-IDG -2.84702 695.0 136
Amelogenin, Y isoform AMELY Tbio Non-IDG -2.86429 712.3 22
Transcriptional repressor scratch 2 SCRT2 Tdark Transcription Factor 0.22 1.09 25
Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific NSD1 Tbio Epigenetic -2.16239 142.5 123
INO80 complex subunit B INO80B Tbio Non-IDG -1.16370 15.1 53
Chromosome alignment-maintaining phosphoprotein 1 CHAMP1 Tbio Non-IDG -0.61730 4.58 106
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 PLCB1 Tbio Enzyme -2.50444 332.8 190
Lamina-associated polypeptide 2, isoform alpha TMPO Tbio Non-IDG -2.11834 246.0 283
E1A-binding protein p400 EP400 Tbio Non-IDG -1.47248 27.6 69