Development Level

Tbio 218 | 10,625
Tchem 41 | 1,890
Tdark 33 | 7,003
Tclin 4 | 602

IMPC Term

preweaning lethality, complete... 33 | 633
embryonic lethality prior to t... 10 | 187
embryonic lethality prior to o... 7 | 148
abnormal embryo size 4 | 112
abnormal lens morphology 4 | 73
preweaning lethality, incomple... 4 | 260
abnormal behavior 3 | 226
abnormal coat/hair pigmentatio... 3 | 54
abnormal rib morphology 3 | 28
cataract 3 | 26
decreased grip strength 3 | 123
increased bone mineral content 3 | 92
increased circulating chloride... 3 | 43
increased circulating sodium l... 3 | 71
increased fasted circulating g... 3 | 68
increased grip strength 3 | 83
increased mean corpuscular vol... 3 | 91
increased sacral vertebrae num... 3 | 62
abnormal forebrain development 2 | 18
abnormal hindbrain development 2 | 24
abnormal midbrain development 2 | 22
abnormal neural tube closure 2 | 37
abnormal placenta size 2 | 10
abnormal retina morphology 2 | 100
abnormal tail morphology 2 | 17
craniofacial phenotype 2 | 9
decreased basophil cell number 2 | 11
decreased body length 2 | 108
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
decreased bone mineral density 2 | 126
decreased caudal vertebrae num... 2 | 49
decreased circulating chloride... 2 | 32
decreased circulating serum al... 2 | 79
decreased eosinophil cell numb... 2 | 41
decreased lumbar vertebrae num... 2 | 62
decreased mean corpuscular hem... 2 | 34
decreased total body fat amoun... 2 | 186
embryonic growth retardation 2 | 28
enlarged lymph nodes 2 | 27
hydrops fetalis 2 | 22
increased bone mineral density 2 | 52
increased circulating alkaline... 2 | 119
increased circulating creatini... 2 | 29
increased lean body mass 2 | 107
increased mean corpuscular hem... 2 | 93
increased mean platelet volume 2 | 19
male infertility 2 | 62
small testis 2 | 37
tremors 2 | 34
vertebral fusion 2 | 23
abnormal behavioral response t... 1 | 52
abnormal craniofacial morpholo... 1 | 12
abnormal gait 1 | 51
abnormal heart morphology 1 | 51
abnormal kidney morphology 1 | 30
abnormal limb bud morphology 1 | 15
abnormal lip morphology 1 | 2
abnormal lung morphology 1 | 15
abnormal optic disc morphology 1 | 10
abnormal placenta morphology 1 | 4
abnormal placenta vasculature 1 | 2
abnormal retinal inner nuclear... 1 | 5
abnormal spinal cord morpholog... 1 | 8
abnormal testis morphology 1 | 30
abnormal thoracic vertebrae mo... 1 | 16
cyanosis 1 | 6
decreased IgG1 level 1 | 4
decreased circulating iron lev... 1 | 25
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased hematocrit 1 | 25
decreased mean corpuscular vol... 1 | 50
decreased total retina thickne... 1 | 20
edema 1 | 11
female infertility 1 | 34
hemorrhage 1 | 12
hypoactivity 1 | 89
increased NK cell number 1 | 19
increased blood urea nitrogen ... 1 | 44
increased circulating HDL chol... 1 | 63
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 53
increased circulating glucose ... 1 | 16
increased circulating potassiu... 1 | 31
increased granulocyte number 1 | 8
increased mean corpuscular hem... 1 | 25
increased red blood cell distr... 1 | 21
increased rib number 1 | 41
narrow eye opening 1 | 15
polydactyly 1 | 22
prenatal lethality prior to he... 1 | 64
respiratory system phenotype 1 | 2
short tibia 1 | 82
shortened PQ interval 1 | 6
small heart 1 | 8
small kidney 1 | 10
small spleen 1 | 11
thrombocytopenia 1 | 46
vertebral transformation 1 | 12

Disease

ovarian cancer 187 | 8,484
medulloblastoma, large-cell 155 | 6,234
osteosarcoma 144 | 7,933
psoriasis 138 | 6,685
lung cancer 134 | 4,466
glioblastoma 119 | 5,572
Breast cancer 105 | 3,094
primitive neuroectodermal tumor 102 | 3,031
group 3 medulloblastoma 96 | 2,254
Cancer 91 | 2,346
atypical teratoid / rhabdoid tumor 90 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 87 | 3,289
malignant mesothelioma 84 | 3,162
non-small cell lung cancer 84 | 2,798
pediatric high grade glioma 81 | 2,712
intraductal papillary-mucinous carcinoma (IPMC) 76 | 2,988
lung adenocarcinoma 75 | 2,713
adrenocortical carcinoma 69 | 1,427
invasive ductal carcinoma 65 | 2,950
oligodendroglioma 58 | 2,849
Carcinoma 52 | 2,147
colon cancer 52 | 1,475
ductal carcinoma in situ 47 | 1,745
Waldenstrons macroglobulinemia 45 | 765
nasopharyngeal carcinoma 45 | 1,056
pancreatic cancer 45 | 2,300
Multiple myeloma 44 | 1,327
astrocytic glioma 42 | 2,241
breast carcinoma 41 | 1,614
ependymoma 40 | 2,514
posterior fossa group A ependymoma 40 | 1,511
atypical teratoid/rhabdoid tumor 39 | 1,095
Endometriosis 38 | 535
Pick disease 36 | 1,893
sonic hedgehog group medulloblastoma 35 | 1,482
Atopic dermatitis 32 | 944
intraductal papillary-mucinous adenoma (IPMA) 32 | 2,956
pilocytic astrocytoma 32 | 3,086
subependymal giant cell astrocytoma 31 | 2,287
ulcerative colitis 31 | 2,087
acute quadriplegic myopathy 29 | 1,157
dermatomyositis 29 | 933
astrocytoma 28 | 1,493
IGA Glomerulonephritis 26 | 454
pituitary cancer 25 | 1,972
Intellectual disability 24 | 573
juvenile dermatomyositis 24 | 1,189
Rheumatoid Arthritis 23 | 1,160
diabetes mellitus 23 | 1,663
group 4 medulloblastoma 23 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 23 | 1,795
lung carcinoma 22 | 2,844
non primary Sjogren syndrome sicca 22 | 840
adult high grade glioma 21 | 2,148
interstitial cystitis 21 | 2,299
primary Sjogren syndrome 21 | 789
medulloblastoma 19 | 1,524
progressive supranuclear palsy 19 | 674
Microcephaly 17 | 149
Prostatic Neoplasms 16 | 471
Stomach Neoplasms 16 | 282
tuberculosis and treatment for 6 months 16 | 686
Mammary Neoplasms 15 | 410
Melanoma 15 | 261
acute myeloid leukemia 15 | 780
gastric carcinoma 15 | 832
inflammatory breast cancer 15 | 404
non-small cell lung carcinoma 15 | 413
posterior fossa group B ependymoma 15 | 1,530
Peripheral Neuropathy 14 | 303
Fanconi's anemia 13 | 50
hepatocellular carcinoma 13 | 532
tuberculosis 13 | 1,557
Adenoma 12 | 165
Alzheimer's disease 12 | 644
Down syndrome 12 | 548
cutaneous lupus erythematosus 12 | 1,056
cystic fibrosis 12 | 1,665
esophageal adenocarcinoma 12 | 737
pancreatic carcinoma 12 | 567
Amyotrophic Lateral Sclerosis 11 | 431
Bladder Neoplasm 11 | 109
Lung Neoplasms 11 | 171
Neurodegenerative disease 11 | 383
Schizophrenia 11 | 501
Ataxia telangiectasia 10 | 31
Disease Progression 10 | 125
Neoplastic Syndromes, Hereditary 10 | 48
Nijmegen breakage syndrome 10 | 23
Pancreatic Neoplasm 10 | 79
Werner syndrome 10 | 29
aldosterone-producing adenoma 10 | 664
Adenoid Cystic Carcinoma 9 | 99
Dyskeratosis congenita 9 | 24
Glioma 9 | 65
Liver carcinoma 9 | 217
Neuroblastoma 8 | 78
gastric cancer 8 | 430
primary pancreatic ductal adenocarcinoma 8 | 1,271
spina bifida 8 | 1,064

Tissue

Endocrine System 296 | 18,512
Blood and immune system 295 | 17,995
Digestive Tract 295 | 18,473
Cardiovascular System 294 | 17,958
Female tissues 294 | 18,647
Male tissues 294 | 17,969
Urinary Tract 294 | 18,444
Liver and Pancreas 293 | 18,136
Nervous System 293 | 18,561
Respiratory system 292 | 17,484
Skin and soft tissues 292 | 18,115

Target Family

Non-IDG 207 | 11,971
Enzyme 44 | 4,146
Epigenetic 16 | 242
Kinase 14 | 634
Transcription Factor 14 | 1,400
TF/Epigenetic 1 | 38

Compartment GO Term

Chromosomal region 296 | 296
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nucleoprotein TPR TPR Tbio Non-IDG -2.07876 130.9 158
G2/mitotic-specific cyclin-B1 CCNB1 Tchem Non-IDG -3.09727 1121.4 955
Proliferating cell nuclear antigen PCNA Tchem Non-IDG -1.10426 11.5 1277
Replication protein A 32 kDa subunit RPA2 Tbio Non-IDG -1.76828 59.7 468
Kinetochore protein Nuf2 NUF2 Tbio Non-IDG -1.66072 48.8 98
Dynein light chain 1, cytoplasmic DYNLL1 Tbio Non-IDG -2.65303 525.6 142
Centromere protein F CENPF Tbio Non-IDG -1.98596 103.0 180
Histone H3-like centromeric protein A CENPA Tbio Non-IDG -2.68837 532.8 347
Protein artemis DCLRE1C Tbio Non-IDG -1.63807 45.4 225
Protein ELYS AHCTF1 Tbio Non-IDG -1.30356 22.8 57