Development Level

Tbio 214 | 11,445
Tchem 36 | 1,598
Tdark 23 | 6,588
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, complete... 46 | 979
embryonic lethality prior to t... 10 | 278
embryonic lethality prior to o... 9 | 239
preweaning lethality, incomple... 8 | 499
abnormal embryo size 7 | 220
cataract 6 | 92
abnormal behavior 5 | 298
abnormal lens morphology 5 | 81
embryonic growth retardation 5 | 106
abnormal tail morphology 4 | 25
increased circulating HDL chol... 4 | 80
abnormal bone structure 3 | 187
abnormal coat-hair pigmentatio... 3 | 64
abnormal craniofacial morpholo... 3 | 33
abnormal seminal vesicle morph... 3 | 114
decreased vertical activity 3 | 208
edema 3 | 59
enlarged lymph nodes 3 | 37
increased bone mineral content 3 | 108
increased circulating alkaline... 3 | 122
increased fasted circulating g... 3 | 76
increased mean corpuscular vol... 3 | 92
increased startle reflex 3 | 112
small testis 3 | 58
abnormal behavioral response t... 2 | 66
abnormal cornea morphology 2 | 31
abnormal heart morphology 2 | 162
abnormal kidney morphology 2 | 65
abnormal limb morphology 2 | 13
abnormal lung morphology 2 | 26
abnormal placenta size 2 | 20
corneal opacity 2 | 32
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased circulating choleste... 2 | 93
decreased circulating serum al... 2 | 82
decreased grip strength 2 | 116
decreased heart left ventricle... 2 | 28
decreased total body fat amoun... 2 | 207
enlarged heart 2 | 210
hemorrhage 2 | 23
impaired glucose tolerance 2 | 75
increased blood urea nitrogen ... 2 | 48
increased bone mineral density 2 | 72
increased circulating chloride... 2 | 41
increased circulating choleste... 2 | 66
increased circulating creatini... 2 | 38
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
male infertility 2 | 123
prenatal lethality prior to he... 2 | 87
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
small kidney 2 | 16
small spleen 2 | 19
vertebral fusion 2 | 23
abnormal cranium morphology 1 | 36
abnormal embryo turning 1 | 31
abnormal neural tube closure 1 | 46
abnormal placenta morphology 1 | 5
abnormal placenta vasculature 1 | 2
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
cardiovascular system phenotyp... 1 | 36
cyanosis 1 | 7
decreased IgG1 level 1 | 8
decreased blood urea nitrogen ... 1 | 51
decreased caudal vertebrae num... 1 | 53
decreased circulating chloride... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased food intake 1 | 13
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased mature B cell number 1 | 7
decreased total retina thickne... 1 | 17
female infertility 1 | 60
hydrometra 1 | 53
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating glucose ... 1 | 24
increased circulating sodium l... 1 | 71
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased mean platelet volume 1 | 45
microphthalmia 1 | 26
polycystic kidney 1 | 15
respiratory system phenotype 1 | 2
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
shortened RR interval 1 | 17
syndactyly 1 | 23
tremors 1 | 39
urinary bladder obstruction 1 | 4

Disease

Carcinoma 183 | 11,493
ovarian cancer 173 | 8,520
medulloblastoma, large-cell 146 | 6,241
osteosarcoma 138 | 7,950
psoriasis 123 | 6,694
group 3 medulloblastoma 122 | 4,104
lung cancer 119 | 4,740
glioblastoma 117 | 5,792
atypical teratoid / rhabdoid tumor 114 | 5,112
Breast cancer 108 | 3,578
primitive neuroectodermal tumor 94 | 3,035
Cancer 91 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 80 | 3,291
ependymoma 76 | 4,679
malignant mesothelioma 75 | 3,232
non-small cell lung cancer 74 | 2,890
adult high grade glioma 72 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 69 | 2,989
adrenocortical carcinoma 65 | 1,428
lung adenocarcinoma 65 | 2,716
invasive ductal carcinoma 61 | 2,951
Kidney cancer 59 | 2,613
oligodendroglioma 53 | 2,850
pancreatic cancer 48 | 2,398
astrocytic glioma 46 | 2,597
Intellectual disability 44 | 1,016
colon cancer 43 | 1,478
ductal carcinoma in situ 43 | 1,745
breast carcinoma 39 | 1,638
Waldenstrons macroglobulinemia 38 | 765
nasopharyngeal carcinoma 38 | 1,058
Multiple myeloma 37 | 1,332
Pick disease 35 | 1,894
Endometriosis 34 | 540
Atopic dermatitis 33 | 952
Short stature 32 | 531
Astrocytoma, Pilocytic 31 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 30 | 2,955
Cognitive delay 29 | 608
Global developmental delay 29 | 608
Mental and motor retardation 29 | 608
subependymal giant cell astrocytoma 29 | 2,287
ulcerative colitis 29 | 1,819
Dull intelligence 28 | 645
Low intelligence 28 | 645
Mental Retardation 28 | 645
Mental deficiency 28 | 645
Poor school performance 28 | 645
Small head 25 | 374
dermatomyositis 25 | 966
Autosomal recessive predisposition 24 | 1,442
acute quadriplegic myopathy 24 | 1,158
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,962
non primary Sjogren syndrome sicca 23 | 891
pediatric high grade glioma 22 | 1,064
Melanoma 21 | 711
Rheumatoid arthritis 21 | 1,191
diabetes mellitus 21 | 1,728
group 4 medulloblastoma 21 | 1,855
interstitial cystitis 21 | 2,312
juvenile dermatomyositis 21 | 1,187
pituitary cancer 21 | 1,972
astrocytoma 20 | 1,146
lung carcinoma 20 | 2,843
tuberculosis 19 | 2,010
Schizophrenia 18 | 1,160
primary Sjogren syndrome 18 | 735
Hypoplastic mandible condyle 17 | 275
Mandibular hypoplasia 17 | 275
Micrognathism 17 | 275
Stomach Neoplasms 17 | 300
progressive supranuclear palsy 17 | 676
Breast Neoplasms 16 | 445
Cryptorchidism 16 | 296
Epilepsy 16 | 792
Liver cancer 16 | 604
Mammary Neoplasms 16 | 425
Fanconi anemia 15 | 56
Microcephaly 15 | 166
Prostatic Neoplasms 15 | 495
acute myeloid leukemia 15 | 783
hepatocellular carcinoma 15 | 547
Alzheimer's disease 14 | 658
Fetal Growth Retardation 14 | 189
Infant, Small for Gestational Age 14 | 176
Intrauterine retardation 14 | 176
Seizures 14 | 596
medulloblastoma 14 | 720
Amyotrophic lateral sclerosis 13 | 451
Lymphoid leukemia 13 | 160
Thrombocytopenia 13 | 197
Failure to gain weight 12 | 365
Lung Neoplasms 12 | 232
Pediatric failure to thrive 12 | 365
cystic fibrosis 12 | 1,696
gastric carcinoma 12 | 807
tuberculosis and treatment for 6 months 12 | 409
Muscle hypotonia 11 | 571
cutaneous lupus erythematosus 11 | 1,057
esophageal adenocarcinoma 11 | 737

Tissue

Endocrine System 274 | 18,159
Female tissues 270 | 17,400
Male tissues 270 | 17,142
Skin and soft tissues 270 | 17,230
Digestive Tract 269 | 17,369
Blood and immune system 268 | 16,909
Liver and Pancreas 267 | 16,750
Respiratory system 266 | 16,393
Urinary Tract 266 | 16,678
Nervous System 265 | 16,725
Cardiovascular System 255 | 15,192

Target Family

Non-IDG 187 | 12,091
Enzyme 43 | 4,145
Transcription Factor 17 | 1,400
Epigenetic 16 | 242
Kinase 13 | 634

Compartment GO Term

Chromosomal region 276 | 276
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CAP-Gly domain-containing linker protein 1 CLIP1 Tbio Non-IDG -2.54943 343.7 221
Telomere length regulation protein TEL2 homolog TELO2 Tbio Non-IDG -0.93554 9.48 94
Sperm-associated antigen 5 SPAG5 Tbio Non-IDG -1.72743 51.4 136
Histone-lysine N-methyltransferase KMT5C KMT5C Tchem Epigenetic 1.18 0.06 46
Nuclear distribution protein nudE homolog 1 NDE1 Tbio Non-IDG -2.01711 96.0 192
Mitotic spindle assembly checkpoint protein MAD1 MAD1L1 Tbio Non-IDG -1.17500 13.6 283
Telomerase protein component 1 TEP1 Tbio Enzyme -1.74492 50.6 71
Spindle and kinetochore-associated protein 2 SKA2 Tbio Non-IDG -1.23206 10.2 108
Protein SGT1 homolog SUGT1 Tbio Non-IDG -0.79781 9.93 183
Cohesin subunit SA-3 STAG3 Tbio Non-IDG -1.30055 20.0 104