Development Level

Tbio 646 | 11,651
Tchem 125 | 1,388
Tdark 84 | 6,593
Tclin 34 | 612

IMPC Phenotype

preweaning lethality, complete... 116 | 979
preweaning lethality, incomple... 39 | 499
embryonic lethality prior to t... 38 | 278
embryonic lethality prior to o... 37 | 239
abnormal embryo size 21 | 220
abnormal behavior 18 | 298
decreased total body fat amoun... 14 | 207
abnormal bone structure 13 | 187
decreased vertical activity 13 | 208
enlarged heart 13 | 210
decreased body weight 12 | 161
embryonic growth retardation 12 | 106
increased startle reflex 12 | 112
male infertility 12 | 123
abnormal heart morphology 10 | 162
abnormal seminal vesicle morph... 10 | 114
decreased bone mineral density 10 | 126
increased circulating HDL chol... 10 | 80
increased mean corpuscular hem... 10 | 96
cataract 9 | 92
increased bone mineral content 9 | 108
prenatal lethality prior to he... 9 | 87
abnormal lens morphology 8 | 81
abnormal retina morphology 8 | 71
impaired glucose tolerance 8 | 75
increased bone mineral density 8 | 72
increased circulating alkaline... 8 | 122
increased lean body mass 8 | 172
increased mean corpuscular vol... 8 | 92
decreased body length 7 | 101
decreased circulating serum al... 7 | 82
hypoactivity 7 | 132
increased circulating choleste... 7 | 66
small testis 7 | 58
decreased bone mineral content 6 | 151
decreased caudal vertebrae num... 6 | 53
decreased circulating alanine ... 6 | 47
decreased circulating choleste... 6 | 93
decreased circulating glucose ... 6 | 126
decreased lean body mass 6 | 135
decreased leukocyte cell numbe... 6 | 73
decreased prepulse inhibition 6 | 82
edema 6 | 59
female infertility 6 | 60
hyperactivity 6 | 148
increased circulating triglyce... 6 | 42
increased mean platelet volume 6 | 45
increased neutrophil cell numb... 6 | 46
abnormal embryo turning 5 | 31
abnormal gait 5 | 69
cardiovascular system phenotyp... 5 | 36
decreased circulating LDL chol... 5 | 38
decreased circulating total pr... 5 | 49
decreased erythrocyte cell num... 5 | 62
decreased grip strength 5 | 116
decreased lymphocyte cell numb... 5 | 83
increased circulating sodium l... 5 | 71
increased fasted circulating g... 5 | 76
increased total body fat amoun... 5 | 134
short tibia 5 | 97
abnormal behavioral response t... 4 | 66
abnormal coat-hair pigmentatio... 4 | 64
abnormal cornea morphology 4 | 31
abnormal eye morphology 4 | 68
abnormal spleen morphology 4 | 55
abnormal tail morphology 4 | 25
corneal opacity 4 | 32
decreased blood urea nitrogen ... 4 | 51
decreased circulating HDL chol... 4 | 68
decreased mean corpuscular vol... 4 | 79
hemorrhage 4 | 23
increased body length 4 | 32
increased circulating chloride... 4 | 41
increased circulating creatini... 4 | 38
increased monocyte cell number 4 | 63
prolonged ST segment 4 | 36
small spleen 4 | 19
thrombocytopenia 4 | 56
vertebral transformation 4 | 12
abnormal bone mineralization 3 | 38
abnormal craniofacial morpholo... 3 | 33
abnormal cranium morphology 3 | 36
abnormal epididymis morphology 3 | 42
abnormal kidney morphology 3 | 65
abnormal lung morphology 3 | 26
abnormal retinal vasculature m... 3 | 27
anophthalmia 3 | 33
decreased circulating alkaline... 3 | 46
decreased circulating insulin ... 3 | 76
decreased circulating triglyce... 3 | 79
decreased fasted circulating g... 3 | 65
decreased hematocrit 3 | 46
decreased total retina thickne... 3 | 17
improved glucose tolerance 3 | 79
increased heart weight 3 | 62
increased hemoglobin content 3 | 45
increased or absent threshold ... 3 | 101
microphthalmia 3 | 26
prenatal lethality 3 | 28
prolonged QT interval 3 | 38

Disease

Carcinoma 590 | 11,493
ovarian cancer 505 | 8,520
osteosarcoma 443 | 7,950
medulloblastoma, large-cell 395 | 6,241
psoriasis 378 | 6,694
lung cancer 365 | 4,740
Cancer 362 | 2,499
glioblastoma 360 | 5,792
group 3 medulloblastoma 324 | 4,104
atypical teratoid / rhabdoid tumor 314 | 5,112
Breast cancer 289 | 3,578
malignant mesothelioma 266 | 3,232
primitive neuroectodermal tumor 254 | 3,035
ependymoma 229 | 4,679
non-small cell lung cancer 215 | 2,890
intraductal papillary-mucinous neoplasm (IPMN) 196 | 3,291
adult high grade glioma 193 | 3,801
lung adenocarcinoma 190 | 2,716
Kidney cancer 188 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 187 | 2,989
invasive ductal carcinoma 185 | 2,951
oligodendroglioma 159 | 2,850
adrenocortical carcinoma 142 | 1,428
pancreatic cancer 132 | 2,398
ductal carcinoma in situ 131 | 1,745
colon cancer 126 | 1,478
breast carcinoma 122 | 1,638
Intellectual disability 116 | 1,016
astrocytic glioma 116 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 116 | 2,955
Multiple myeloma 114 | 1,332
diabetes mellitus 107 | 1,728
Astrocytoma, Pilocytic 105 | 3,081
astrocytoma 100 | 1,146
subependymal giant cell astrocytoma 98 | 2,287
ulcerative colitis 93 | 1,819
tuberculosis 92 | 2,010
Rheumatoid arthritis 90 | 1,191
Schizophrenia 90 | 1,160
Waldenstrons macroglobulinemia 88 | 765
lung carcinoma 88 | 2,843
group 4 medulloblastoma 87 | 1,855
pituitary cancer 86 | 1,972
Pick disease 85 | 1,894
Short stature 84 | 531
Endometriosis 81 | 540
acute quadriplegic myopathy 81 | 1,158
nasopharyngeal carcinoma 81 | 1,058
pediatric high grade glioma 81 | 1,064
dermatomyositis 80 | 966
interstitial cystitis 80 | 2,312
juvenile dermatomyositis 78 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 77 | 1,962
Breast Neoplasms 76 | 445
Dull intelligence 75 | 645
Low intelligence 75 | 645
Mental Retardation 75 | 645
Mental deficiency 75 | 645
Poor school performance 75 | 645
Mammary Neoplasms 74 | 425
Autosomal recessive predisposition 70 | 1,442
Cognitive delay 68 | 608
Global developmental delay 68 | 608
Mental and motor retardation 68 | 608
Atopic dermatitis 65 | 952
Small head 65 | 374
Cryptorchidism 63 | 296
Epilepsy 59 | 792
Prostatic Neoplasms 59 | 495
acute myeloid leukemia 58 | 783
Seizures 55 | 596
cystic fibrosis 55 | 1,696
primary Sjogren syndrome 54 | 735
Alzheimer's disease 52 | 658
Stomach Neoplasms 51 | 300
non primary Sjogren syndrome sicca 51 | 891
Melanoma 50 | 711
Obesity 50 | 678
Hypoplastic mandible condyle 49 | 275
Mandibular hypoplasia 49 | 275
Micrognathism 49 | 275
Muscle hypotonia 49 | 571
medulloblastoma 49 | 720
Liver cancer 47 | 604
hepatocellular carcinoma 47 | 547
Lung Neoplasms 46 | 232
primary pancreatic ductal adenocarcinoma 46 | 1,109
Bipolar Disorder 44 | 666
Anemia 42 | 365
Failure to gain weight 42 | 365
Fetal Growth Retardation 42 | 189
Infant, Small for Gestational Age 42 | 176
Intrauterine retardation 42 | 176
Pediatric failure to thrive 42 | 365
pancreatic carcinoma 42 | 562
gastric cancer 41 | 459
spina bifida 41 | 1,074
aldosterone-producing adenoma 40 | 665
cutaneous lupus erythematosus 40 | 1,057
gastric carcinoma 39 | 807

Tissue

Endocrine System 872 | 18,159
Digestive Tract 862 | 17,369
Female tissues 859 | 17,400
Skin and soft tissues 853 | 17,230
Male tissues 852 | 17,142
Blood and immune system 851 | 16,909
Liver and Pancreas 842 | 16,750
Respiratory system 838 | 16,393
Urinary Tract 838 | 16,678
Nervous System 836 | 16,725
Cardiovascular System 803 | 15,192

Target Family

Non-IDG 466 | 12,091
Transcription Factor 146 | 1,400
Enzyme 135 | 4,145
Epigenetic 89 | 242
Kinase 27 | 634
Nuclear Receptor 14 | 48
TF/Epigenetic 12 | 38

Compartment GO Term

Chromosomal part 889 | 889
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
COP9 signalosome complex subunit 9 COPS9 Tbio Non-IDG 0.21 0.92 14
Transcriptional repressor scratch 2 SCRT2 Tdark Transcription Factor 0.22 1.09 25
INO80 complex subunit B INO80B Tbio Non-IDG -1.16370 15.1 53
Chromosome alignment-maintaining phosphoprotein 1 CHAMP1 Tbio Non-IDG -0.61730 4.58 106
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 PLCB1 Tbio Enzyme -2.50444 332.8 190
Lamina-associated polypeptide 2, isoform alpha TMPO Tbio Non-IDG -2.11834 246.0 283
E1A-binding protein p400 EP400 Tbio Non-IDG -1.47248 27.6 69
Protein KASH5 CCDC155 Tdark Non-IDG -0.58600 3.79 39
Chromobox protein homolog 3 CBX3 Tbio Epigenetic -2.00023 90.5 366
Putative uncharacterized protein encoded by MIR7-3HG MIR7-3HG Tdark Non-IDG -0.12740 2.08 0