Development Level

Tbio 357 | 10,625
Tchem 117 | 1,890
Tdark 49 | 7,003
Tclin 25 | 602

IMPC Term

preweaning lethality, complete... 32 | 633
preweaning lethality, incomple... 24 | 260
abnormal behavior 12 | 226
embryonic lethality prior to o... 12 | 148
embryonic lethality prior to t... 12 | 187
decreased total body fat amoun... 11 | 186
decreased body weight 10 | 174
decreased lean body mass 10 | 195
abnormal embryo size 8 | 112
decreased body length 8 | 108
increased grip strength 8 | 83
increased sacral vertebrae num... 7 | 62
decreased lumbar vertebrae num... 6 | 62
decreased caudal vertebrae num... 5 | 49
decreased circulating choleste... 5 | 85
decreased mean corpuscular hem... 5 | 34
decreased rib number 5 | 59
enlarged heart 5 | 111
hypoactivity 5 | 89
increased bone mineral content 5 | 92
increased bone mineral density 5 | 52
increased circulating choleste... 5 | 53
increased circulating triglyce... 5 | 24
increased lean body mass 5 | 107
increased mean corpuscular hem... 5 | 93
abnormal bone structure 4 | 131
abnormal eye morphology 4 | 38
abnormal gait 4 | 51
abnormal retina morphology 4 | 100
decreased bone mineral content 4 | 157
decreased circulating LDL chol... 4 | 37
decreased circulating serum al... 4 | 79
decreased circulating total pr... 4 | 41
decreased grip strength 4 | 123
decreased hemoglobin content 4 | 53
decreased leukocyte cell numbe... 4 | 54
decreased mean corpuscular vol... 4 | 50
female infertility 4 | 34
hydrops fetalis 4 | 22
increased circulating HDL chol... 4 | 63
increased circulating sodium l... 4 | 71
increased or absent threshold ... 4 | 128
male infertility 4 | 62
prenatal lethality prior to he... 4 | 64
abnormal coat/hair pigmentatio... 3 | 54
abnormal lens morphology 3 | 73
abnormal neural tube closure 3 | 37
abnormal seminal vesicle morph... 3 | 47
abnormal spleen morphology 3 | 36
abnormal tooth morphology 3 | 24
cataract 3 | 26
decreased blood urea nitrogen ... 3 | 31
decreased bone mineral density 3 | 126
decreased circulating HDL chol... 3 | 77
decreased circulating alanine ... 3 | 53
decreased circulating alkaline... 3 | 41
decreased circulating glucose ... 3 | 121
decreased circulating triglyce... 3 | 83
decreased effector memory CD8-... 3 | 24
decreased heart weight 3 | 44
decreased prepulse inhibition 3 | 52
hyperactivity 3 | 108
increased body length 3 | 20
increased body weight 3 | 42
increased circulating alkaline... 3 | 119
increased mean corpuscular vol... 3 | 91
oligodactyly 3 | 14
short tibia 3 | 82
small testis 3 | 37
thrombocytopenia 3 | 46
vertebral fusion 3 | 23
abnormal coat appearance 2 | 25
abnormal coping response 2 | 12
abnormal cornea morphology 2 | 24
abnormal epididymis morphology 2 | 31
abnormal head morphology 2 | 10
abnormal heart morphology 2 | 51
abnormal retinal pigmentation 2 | 61
abnormal rib morphology 2 | 28
abnormal startle reflex 2 | 14
abnormal testis morphology 2 | 30
cardiovascular system phenotyp... 2 | 35
corneal opacity 2 | 25
decreased Ly6C high monocyte n... 2 | 18
decreased circulating insulin ... 2 | 75
decreased eosinophil cell numb... 2 | 41
decreased fasted circulating g... 2 | 49
decreased hematocrit 2 | 25
decreased lactate dehydrogenas... 2 | 14
embryonic growth retardation 2 | 28
increased CD4-positive, CD25-p... 2 | 18
increased blood urea nitrogen ... 2 | 44
increased circulating chloride... 2 | 43
increased circulating creatini... 2 | 29
increased circulating iron lev... 2 | 25
increased heart weight 2 | 37
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 25
increased mean platelet volume 2 | 19
increased startle reflex 2 | 38

Disease

ovarian cancer 305 | 8,492
osteosarcoma 275 | 7,933
Cancer 256 | 2,346
psoriasis 223 | 6,685
medulloblastoma, large-cell 219 | 6,234
glioblastoma 218 | 5,572
lung cancer 213 | 4,473
malignant mesothelioma 160 | 3,163
atypical teratoid / rhabdoid tumor 159 | 4,369
Breast cancer 144 | 3,099
primitive neuroectodermal tumor 144 | 3,031
pediatric high grade glioma 117 | 2,712
non-small cell lung cancer 116 | 2,798
invasive ductal carcinoma 115 | 2,950
lung adenocarcinoma 111 | 2,714
Carcinoma 102 | 2,147
intraductal papillary-mucinous neoplasm (IPMN) 102 | 3,289
intraductal papillary-mucinous carcinoma (IPMC) 100 | 2,988
oligodendroglioma 98 | 2,849
ependymoma 94 | 2,514
group 3 medulloblastoma 91 | 2,254
astrocytoma 87 | 1,493
diabetes mellitus 83 | 1,663
intraductal papillary-mucinous adenoma (IPMA) 78 | 2,956
group 4 medulloblastoma 76 | 1,875
ductal carcinoma in situ 75 | 1,745
Rheumatoid Arthritis 73 | 1,171
pancreatic cancer 73 | 2,300
Multiple myeloma 72 | 1,328
colon cancer 72 | 1,475
pilocytic astrocytoma 72 | 3,086
adrenocortical carcinoma 70 | 1,427
breast carcinoma 69 | 1,614
ulcerative colitis 69 | 2,087
subependymal giant cell astrocytoma 64 | 2,287
astrocytic glioma 62 | 2,241
lung carcinoma 61 | 2,844
pituitary cancer 61 | 1,972
posterior fossa group A ependymoma 57 | 1,511
sonic hedgehog group medulloblastoma 56 | 1,482
Mammary Neoplasms 55 | 410
medulloblastoma 54 | 1,524
acute quadriplegic myopathy 53 | 1,157
Pick disease 52 | 1,893
interstitial cystitis 51 | 2,299
Intellectual disability 50 | 573
dermatomyositis 49 | 967
Waldenstrons macroglobulinemia 48 | 765
juvenile dermatomyositis 48 | 1,189
tuberculosis 47 | 1,563
atypical teratoid/rhabdoid tumor 46 | 1,095
Endometriosis 44 | 535
pancreatic ductal adenocarcinoma liver metastasis 44 | 1,795
cystic fibrosis 43 | 1,670
adult high grade glioma 42 | 2,148
Obesity 41 | 616
acute myeloid leukemia 41 | 785
Prostatic Neoplasms 40 | 471
primary pancreatic ductal adenocarcinoma 40 | 1,271
nasopharyngeal carcinoma 39 | 1,056
Alzheimer's disease 35 | 644
Stomach Neoplasms 34 | 282
Liver carcinoma 33 | 217
Atopic dermatitis 31 | 944
Kidney disease 31 | 397
Lung Neoplasms 31 | 171
hepatocellular carcinoma 31 | 550
spina bifida 31 | 1,064
aldosterone-producing adenoma 30 | 664
primary Sjogren syndrome 30 | 789
Vascular disease 29 | 281
cutaneous lupus erythematosus 28 | 1,056
Adenoma 27 | 165
Heart disease 27 | 279
gastric cancer 26 | 436
gastric carcinoma 26 | 832
pancreatic carcinoma 26 | 567
IGA Glomerulonephritis 24 | 454
Melanoma 24 | 261
non-small cell lung carcinoma 24 | 413
Down syndrome 23 | 548
Parkinson's disease 23 | 364
inflammatory breast cancer 23 | 404
non primary Sjogren syndrome sicca 23 | 840
Adenocarcinoma 22 | 115
posterior fossa group B ependymoma 22 | 1,530
Adenoid Cystic Carcinoma 21 | 99
Anemia 21 | 252
Arthritis 21 | 248
Schizophrenia 21 | 503
esophageal adenocarcinoma 21 | 737
Bladder Neoplasm 20 | 109
Liver disease 20 | 219
Neoplastic Cell Transformation 20 | 81
autosomal dominant Emery-Dreifuss muscular dystrophy 20 | 499
Asthma 19 | 349
Diabetes Mellitus, Non-Insulin-Dependent 19 | 161
active Crohn's disease 19 | 918
progressive supranuclear palsy 19 | 674
tuberculosis and treatment for 6 months 19 | 686

Tissue

Female tissues 541 | 18,647
Blood and immune system 538 | 17,995
Digestive Tract 536 | 18,473
Liver and Pancreas 536 | 18,136
Male tissues 536 | 17,969
Nervous System 534 | 18,561
Endocrine System 533 | 18,512
Urinary Tract 532 | 18,444
Cardiovascular System 528 | 17,958
Respiratory system 520 | 17,484
Skin and soft tissues 517 | 18,115

Target Family

Non-IDG 236 | 11,969
Transcription Factor 125 | 1,400
Epigenetic 85 | 242
Enzyme 58 | 4,146
Kinase 16 | 634
Nuclear Receptor 14 | 48
TF/Epigenetic 14 | 38

Compartment GO Term

Chromatin 548 | 548
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bromodomain adjacent to zinc finger domain protein 2A BAZ2A Tchem TF/Epigenetic -2.05410 110.9 33
Tyrosine-protein kinase BAZ1B BAZ1B Tbio Epigenetic -1.42830 30.5 140
Transcription elongation factor SPT6 SUPT6H Tbio Non-IDG -1.76801 61.0 119
Cell division control protein 6 homolog CDC6 Tchem Non-IDG -2.49821 321.6 473
Probable global transcription activator SNF2L1 SMARCA1 Tbio Non-IDG -2.18842 137.5 94
Chromodomain-helicase-DNA-binding protein 4 CHD4 Tbio Epigenetic -2.19846 145.8 170
Breast cancer metastasis-suppressor 1-like protein BRMS1L Tbio Non-IDG -1.66955 52.7 94
Cohesin subunit SA-1 STAG1 Tbio Non-IDG -2.44719 274.6 177
Histone chaperone ASF1B ASF1B Tbio Non-IDG -0.98695 10.4 108
AF4/FMR2 family member 4 AFF4 Tbio Transcription Factor -2.52668 332.1 141