Development Level

Tbio 45 | 10,625
Tchem 18 | 1,890
Tclin 3 | 602
Tdark 1 | 7,003

Collection

Eligible non-olfactory GPCR Proteins 1 | 145

IMPC Term

abnormal lens morphology 3 | 73
preweaning lethality, complete... 3 | 633
decreased NK T cell number 2 | 28
decreased bone mineral density 2 | 126
decreased total body fat amoun... 2 | 186
increased KLRG1-positive NK ce... 2 | 9
increased Ly6C high monocyte n... 2 | 12
increased NK cell number 2 | 19
increased mean corpuscular hem... 2 | 93
increased mean corpuscular vol... 2 | 91
increased monocyte cell number 2 | 27
preweaning lethality, incomple... 2 | 260
abnormal bone structure 1 | 131
abnormal clavicle morphology 1 | 5
abnormal coat/ hair morphology 1 | 18
abnormal retina morphology 1 | 100
abnormal rib morphology 1 | 28
absent pinna reflex 1 | 21
absent vibrissae 1 | 14
decreased CD4-positive, CD25-p... 1 | 24
decreased CD4-positive, alpha ... 1 | 19
decreased T cell number 1 | 31
decreased alpha-beta T cell nu... 1 | 12
decreased body length 1 | 108
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating amylase ... 1 | 24
decreased circulating choleste... 1 | 85
decreased circulating fructosa... 1 | 31
decreased circulating glucose ... 1 | 121
decreased dendritic cell numbe... 1 | 3
decreased effector memory CD4-... 1 | 6
decreased effector memory CD8-... 1 | 24
decreased gamma-delta T cell n... 1 | 18
decreased grip strength 1 | 123
decreased immature NK cell num... 1 | 1
decreased lean body mass 1 | 195
decreased mature B cell number 1 | 25
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
female infertility 1 | 34
impaired glucose tolerance 1 | 52
increased B cell number 1 | 23
increased CD4-positive, alpha ... 1 | 15
increased CD8-positive, alpha-... 1 | 11
increased Ly6C low monocyte nu... 1 | 8
increased circulating alkaline... 1 | 119
increased circulating bilirubi... 1 | 16
increased circulating iron lev... 1 | 25
increased circulating serum al... 1 | 25
increased effector memory CD4-... 1 | 15
increased effector memory CD8-... 1 | 14
increased eosinophil cell numb... 1 | 9
increased heart weight 1 | 37
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased mature B cell number 1 | 12
increased mature NK cell numbe... 1 | 1
increased or absent threshold ... 1 | 128
increased plasmacytoid dendrit... 1 | 1
male infertility 1 | 62
prenatal lethality prior to he... 1 | 64
thrombocytopenia 1 | 46

Disease

ovarian cancer 32 | 8,492
osteosarcoma 24 | 7,933
lung cancer 22 | 4,473
Multiple myeloma 20 | 1,328
Cancer 19 | 2,346
glioblastoma 19 | 5,572
psoriasis 19 | 6,685
diabetes mellitus 15 | 1,663
medulloblastoma, large-cell 15 | 6,234
invasive ductal carcinoma 12 | 2,950
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
lung adenocarcinoma 11 | 2,714
non-small cell lung cancer 11 | 2,798
Waldenstrons macroglobulinemia 10 | 765
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,289
primitive neuroectodermal tumor 10 | 3,031
Breast cancer 9 | 3,099
Neurodegenerative disease 9 | 383
ependymoma 9 | 2,514
lung carcinoma 9 | 2,844
oligodendroglioma 9 | 2,849
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,795
subependymal giant cell astrocytoma 9 | 2,287
Obesity 8 | 616
Pick disease 8 | 1,893
malignant mesothelioma 8 | 3,163
pediatric high grade glioma 8 | 2,712
pilocytic astrocytoma 8 | 3,086
Anemia 7 | 252
Kidney disease 7 | 397
astrocytoma 7 | 1,493
atypical teratoid/rhabdoid tumor 7 | 1,095
sonic hedgehog group medulloblastoma 7 | 1,482
Heart disease 6 | 279
Liver carcinoma 6 | 217
Stomach Neoplasms 6 | 282
acute quadriplegic myopathy 6 | 1,157
adult high grade glioma 6 | 2,148
atypical teratoid / rhabdoid tumor 6 | 4,369
cystic fibrosis 6 | 1,670
dermatomyositis 6 | 967
ductal carcinoma in situ 6 | 1,745
group 3 medulloblastoma 6 | 2,254
pancreatic cancer 6 | 2,300
pituitary cancer 6 | 1,972
tuberculosis 6 | 1,563
ulcerative colitis 6 | 2,087
Carcinoma 5 | 2,147
Hypertension 5 | 293
Rheumatoid Arthritis 5 | 1,171
Toxic encephalopathy 5 | 131
Vascular disease 5 | 281
astrocytic glioma 5 | 2,241
interstitial cystitis 5 | 2,299
juvenile dermatomyositis 5 | 1,189
medulloblastoma 5 | 1,524
Atherosclerosis 4 | 275
Atopic dermatitis 4 | 944
Cerebrovascular disease 4 | 231
Coronary artery disease 4 | 240
Diamond-Blackfan anemia 4 | 30
Duchenne muscular dystrophy 4 | 602
Epilepsy 4 | 346
Glycogen storage disease V 4 | 7
Malaria 4 | 140
Myopathy 4 | 128
Osteoporosis 4 | 259
Schizophrenia 4 | 503
adrenocortical carcinoma 4 | 1,427
breast carcinoma 4 | 1,614
colon cancer 4 | 1,475
cutaneous lupus erythematosus 4 | 1,056
hepatocellular carcinoma 4 | 550
inflammatory breast cancer 4 | 404
nasopharyngeal carcinoma 4 | 1,056
Amyotrophic Lateral Sclerosis 3 | 432
Anoxia 3 | 33
Arthritis 3 | 248
Brain disease 3 | 84
Chagas disease 3 | 34
Contact Dermatitis 3 | 80
Disease Progression 3 | 125
Glaucoma 3 | 135
Hypercalcemia 3 | 37
Hypersensitivity reaction type II disease 3 | 235
Liver disease 3 | 219
Lung Neoplasms 3 | 171
Parkinson Disease 3 | 105
Polycystic Ovary Syndrome 3 | 335
Prostatic Neoplasms 3 | 471
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
chronic rhinosinusitis 3 | 512
esophageal adenocarcinoma 3 | 737
gastric cancer 3 | 436
gastric carcinoma 3 | 832
group 4 medulloblastoma 3 | 1,875
primary Sjogren syndrome 3 | 789
primary pancreatic ductal adenocarcinoma 3 | 1,271
tuberculosis and treatment for 6 months 3 | 686

Tissue

Digestive Tract 64 | 18,473
Female tissues 64 | 18,647
Nervous System 64 | 18,561
Urinary Tract 64 | 18,444
Blood and immune system 63 | 17,995
Cardiovascular System 63 | 17,958
Endocrine System 63 | 18,512
Liver and Pancreas 63 | 18,136
Male tissues 63 | 17,969
Respiratory system 63 | 17,484
Skin and soft tissues 63 | 18,115

Target Family

Non-IDG 34 | 11,969
Enzyme 27 | 4,146
Kinase 2 | 634
TF/Epigenetic 2 | 38
GPCR 1 | 408
Transporter 1 | 473

Compartment GO Term

Chloroplast 67 | 67
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATPase inhibitor, mitochondrial ATPIF1 Tbio Enzyme -2.17521 137.1 147
5,6-dihydroxyindole-2-carboxylic acid oxidase TYRP1 Tchem Enzyme -2.93891 844.0 215
Sodium/potassium-transporting ATPase subunit beta-3 ATP1B3 Tclin Transporter -1.08214 10.9 189
Glyceraldehyde-3-phosphate dehydrogenase GAPDH Tchem Enzyme -3.66772 4499.1 1649
DNA-(apurinic or apyrimidinic site) lyase APEX1 Tchem Enzyme -3.44060 2815.1 550
Megakaryocyte-associated tyrosine-protein kinase MATK Tbio Kinase -2.95780 745.7 230
Spexin SPX Tbio Non-IDG -2.76281 568.1 18
Sorting and assembly machinery component 50 homolog SAMM50 Tbio Non-IDG -2.06745 112.4 108
CTP synthase 1 CTPS1 Tbio Enzyme -2.24649 173.3 86
40S ribosomal protein S19 RPS19 Tbio Non-IDG -3.12258 1305.7 243