Development Level

Tbio 48 | 11,445
Tchem 16 | 1,598
Tclin 3 | 613
Tdark 1 | 6,588

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

decreased bone mineral density 2 | 126
increased circulating choleste... 2 | 66
increased mean corpuscular hem... 2 | 96
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal bone structure 1 | 187
abnormal clavicle morphology 1 | 6
abnormal coat- hair morphology 1 | 19
abnormal retinal vasculature m... 1 | 27
abnormal rib morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal vibrissa morphology 1 | 25
absent pinna reflex 1 | 23
cataract 1 | 92
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased grip strength 1 | 116
decreased mean corpuscular hem... 1 | 31
decreased mean platelet volume 1 | 25
decreased red blood cell distr... 1 | 41
impaired glucose tolerance 1 | 75
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating iron lev... 1 | 30
increased circulating serum al... 1 | 22
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
male infertility 1 | 123
thrombocytopenia 1 | 56

Disease

Carcinoma 38 | 11,493
ovarian cancer 31 | 8,520
osteosarcoma 23 | 7,950
lung cancer 22 | 4,740
psoriasis 21 | 6,694
glioblastoma 20 | 5,792
Cancer 19 | 2,499
Multiple myeloma 19 | 1,332
diabetes mellitus 17 | 1,728
medulloblastoma, large-cell 15 | 6,241
group 3 medulloblastoma 14 | 4,104
non-small cell lung cancer 14 | 2,890
Breast cancer 12 | 3,578
invasive ductal carcinoma 12 | 2,951
Autosomal recessive predisposition 11 | 1,442
lung adenocarcinoma 11 | 2,716
Neurodegenerative disease 10 | 414
adult high grade glioma 10 | 3,801
atypical teratoid / rhabdoid tumor 10 | 5,112
ependymoma 10 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
primitive neuroectodermal tumor 10 | 3,035
Astrocytoma, Pilocytic 9 | 3,081
Waldenstrons macroglobulinemia 9 | 765
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
lung carcinoma 9 | 2,843
malignant mesothelioma 9 | 3,232
oligodendroglioma 9 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
Anemia 8 | 365
subependymal giant cell astrocytoma 8 | 2,287
Heart disease 7 | 306
Obesity 7 | 678
Pick disease 7 | 1,894
Schizophrenia 7 | 1,160
astrocytoma 7 | 1,146
tuberculosis 7 | 2,010
Carcinoma, Hepatocellular 6 | 228
Epilepsy 6 | 792
Kidney cancer 6 | 2,613
Kidney disease 6 | 430
Liver carcinoma 6 | 240
Stomach Neoplasms 6 | 300
Toxic encephalopathy 6 | 141
acute quadriplegic myopathy 6 | 1,158
cystic fibrosis 6 | 1,696
ductal carcinoma in situ 6 | 1,745
pancreatic cancer 6 | 2,398
pituitary cancer 6 | 1,972
ulcerative colitis 6 | 1,819
Coronary artery disease 5 | 268
Hypertension 5 | 396
Osteoporosis 5 | 363
Rheumatoid arthritis 5 | 1,191
Seizures 5 | 596
Vascular disease 5 | 319
astrocytic glioma 5 | 2,597
dermatomyositis 5 | 966
interstitial cystitis 5 | 2,312
juvenile dermatomyositis 5 | 1,187
Atherosclerosis 4 | 291
Atopic dermatitis 4 | 952
Autosomal recessive Robinow syndrome 4 | 27
Cerebrovascular disease 4 | 238
Diamond-Blackfan anemia 4 | 31
Duchenne muscular dystrophy 4 | 601
Glycogen storage disease V 4 | 9
Malaria 4 | 160
Muscle hypotonia 4 | 571
adrenocortical carcinoma 4 | 1,428
breast carcinoma 4 | 1,638
chronic rhinosinusitis 4 | 512
colon cancer 4 | 1,478
cutaneous lupus erythematosus 4 | 1,057
gastric cancer 4 | 459
group 4 medulloblastoma 4 | 1,855
hepatocellular carcinoma 4 | 547
nasopharyngeal carcinoma 4 | 1,058
pediatric high grade glioma 4 | 1,064
Arthritis 3 | 290
Contact Dermatitis 3 | 81
Disease Progression 3 | 136
Eye disease 3 | 62
Glaucoma 3 | 239
Hepatomegaly 3 | 285
Hypersensitivity reaction type II disease 3 | 253
Hypoglycemia 3 | 152
Lung Neoplasms 3 | 232
Mood Disorders 3 | 184
Polycystic ovary syndrome 3 | 360
Prostatic Neoplasms 3 | 495
Strabismus 3 | 270
atypical teratoid/rhabdoid tumor 3 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
esophageal adenocarcinoma 3 | 737
fibroadenoma 3 | 559
posterior fossa group B ependymoma 3 | 416
primary Sjogren syndrome 3 | 735
spina bifida 3 | 1,074

Tissue

Blood and immune system 65 | 16,909
Digestive Tract 63 | 17,369
Endocrine System 63 | 18,159
Female tissues 63 | 17,400
Liver and Pancreas 63 | 16,750
Nervous System 63 | 16,725
Male tissues 62 | 17,142
Skin and soft tissues 62 | 17,230
Respiratory system 61 | 16,393
Urinary Tract 61 | 16,678
Cardiovascular System 58 | 15,192

Target Family

Non-IDG 34 | 12,091
Enzyme 29 | 4,145
Kinase 2 | 634
GPCR 1 | 408
TF/Epigenetic 1 | 38
Transporter 1 | 473

Compartment GO Term

Chloroplast 68 | 68
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CTP synthase 1 CTPS1 Tbio Enzyme -2.29349 196.5 107
Spexin SPX Tbio Non-IDG -2.81062 637.9 19
Cytochrome P450 26A1 CYP26A1 Tchem Enzyme -2.44772 290.1 197
5,6-dihydroxyindole-2-carboxylic acid oxidase TYRP1 Tbio Enzyme -2.95336 876.7 309
40S ribosomal protein S19 RPS19 Tbio Non-IDG -3.14746 1380.8 267
Isoleucine--tRNA ligase, cytoplasmic IARS Tchem Enzyme -3.11190 1198.0 95
60S ribosomal protein L36 RPL36 Tbio Non-IDG -1.62928 39.9 123
Megakaryocyte-associated tyrosine-protein kinase MATK Tbio Kinase -2.98596 792.3 265
Maltase-glucoamylase, intestinal MGAM Tclin Enzyme -4.52158 32564.4 32
Interferon alpha-17 IFNA17 Tbio Non-IDG -2.39299 231.1 56