Development Level

Tbio 45 | 10,625
Tchem 18 | 1,890
Tclin 4 | 602
Tdark 1 | 7,003

Collection

Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

abnormal lens morphology 3 | 73
preweaning lethality, complete... 3 | 633
decreased NK T cell number 2 | 28
decreased bone mineral density 2 | 126
decreased total body fat amoun... 2 | 186
increased KLRG1-positive NK ce... 2 | 9
increased Ly6C high monocyte n... 2 | 12
increased NK cell number 2 | 19
increased mean corpuscular hem... 2 | 93
increased mean corpuscular vol... 2 | 91
increased monocyte cell number 2 | 27
preweaning lethality, incomple... 2 | 260
abnormal bone structure 1 | 131
abnormal clavicle morphology 1 | 5
abnormal coat/ hair morphology 1 | 18
abnormal retina morphology 1 | 100
abnormal rib morphology 1 | 28
absent pinna reflex 1 | 21
absent vibrissae 1 | 14
decreased CD4-positive, CD25-p... 1 | 24
decreased CD4-positive, alpha ... 1 | 19
decreased T cell number 1 | 31
decreased alpha-beta T cell nu... 1 | 12
decreased body length 1 | 108
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating amylase ... 1 | 24
decreased circulating choleste... 1 | 85
decreased circulating fructosa... 1 | 31
decreased circulating glucose ... 1 | 121
decreased dendritic cell numbe... 1 | 3
decreased effector memory CD4-... 1 | 6
decreased effector memory CD8-... 1 | 24
decreased gamma-delta T cell n... 1 | 18
decreased grip strength 1 | 123
decreased immature NK cell num... 1 | 1
decreased lean body mass 1 | 195
decreased mature B cell number 1 | 25
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
female infertility 1 | 34
impaired glucose tolerance 1 | 52
increased B cell number 1 | 23
increased CD4-positive, alpha ... 1 | 15
increased CD8-positive, alpha-... 1 | 11
increased Ly6C low monocyte nu... 1 | 8
increased circulating alkaline... 1 | 119
increased circulating bilirubi... 1 | 16
increased circulating iron lev... 1 | 25
increased circulating serum al... 1 | 25
increased effector memory CD4-... 1 | 15
increased effector memory CD8-... 1 | 14
increased eosinophil cell numb... 1 | 9
increased heart weight 1 | 37
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased mature B cell number 1 | 12
increased mature NK cell numbe... 1 | 1
increased or absent threshold ... 1 | 128
increased plasmacytoid dendrit... 1 | 1
male infertility 1 | 62
prenatal lethality prior to he... 1 | 64
thrombocytopenia 1 | 46

Disease

ovarian cancer 32 | 8,484
osteosarcoma 24 | 7,933
lung cancer 22 | 4,466
Cancer 20 | 2,346
Multiple myeloma 20 | 1,327
glioblastoma 20 | 5,572
psoriasis 20 | 6,685
diabetes mellitus 15 | 1,663
medulloblastoma, large-cell 15 | 6,234
invasive ductal carcinoma 12 | 2,950
non-small cell lung cancer 12 | 2,798
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
lung adenocarcinoma 11 | 2,713
Waldenstrons macroglobulinemia 10 | 765
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,289
primitive neuroectodermal tumor 10 | 3,031
Breast cancer 9 | 3,094
Neurodegenerative disease 9 | 383
ependymoma 9 | 2,514
lung carcinoma 9 | 2,844
oligodendroglioma 9 | 2,849
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,795
subependymal giant cell astrocytoma 9 | 2,287
Obesity 8 | 616
Pick disease 8 | 1,893
malignant mesothelioma 8 | 3,162
pediatric high grade glioma 8 | 2,712
pilocytic astrocytoma 8 | 3,086
Anemia 7 | 252
Kidney disease 7 | 396
astrocytoma 7 | 1,493
atypical teratoid/rhabdoid tumor 7 | 1,095
sonic hedgehog group medulloblastoma 7 | 1,482
Heart disease 6 | 279
Liver carcinoma 6 | 217
Stomach Neoplasms 6 | 282
acute quadriplegic myopathy 6 | 1,157
adult high grade glioma 6 | 2,148
atypical teratoid / rhabdoid tumor 6 | 4,369
cystic fibrosis 6 | 1,665
dermatomyositis 6 | 933
ductal carcinoma in situ 6 | 1,745
group 3 medulloblastoma 6 | 2,254
medulloblastoma 6 | 1,524
pancreatic cancer 6 | 2,300
pituitary cancer 6 | 1,972
tuberculosis 6 | 1,557
ulcerative colitis 6 | 2,087
Carcinoma 5 | 2,147
Hypertension 5 | 287
Rheumatoid Arthritis 5 | 1,160
Toxic encephalopathy 5 | 131
Vascular disease 5 | 281
astrocytic glioma 5 | 2,241
inflammatory breast cancer 5 | 404
interstitial cystitis 5 | 2,299
juvenile dermatomyositis 5 | 1,189
Atherosclerosis 4 | 275
Atopic dermatitis 4 | 944
Cerebrovascular disease 4 | 231
Coronary artery disease 4 | 240
Diamond-Blackfan anemia 4 | 28
Duchenne muscular dystrophy 4 | 602
Epilepsy 4 | 346
Glycogen storage disease V 4 | 7
Malaria 4 | 140
Myopathy 4 | 128
Osteoporosis 4 | 257
Schizophrenia 4 | 501
adrenocortical carcinoma 4 | 1,427
breast carcinoma 4 | 1,614
chronic rhinosinusitis 4 | 512
colon cancer 4 | 1,475
cutaneous lupus erythematosus 4 | 1,056
hepatocellular carcinoma 4 | 532
nasopharyngeal carcinoma 4 | 1,056
Amyotrophic Lateral Sclerosis 3 | 431
Anoxia 3 | 33
Arthritis 3 | 248
Brain disease 3 | 83
Chagas disease 3 | 34
Contact Dermatitis 3 | 80
Disease Progression 3 | 125
Glaucoma 3 | 134
Hypersensitivity reaction type II disease 3 | 235
Liver disease 3 | 219
Lung Neoplasms 3 | 171
Parkinson Disease 3 | 102
Polycystic Ovary Syndrome 3 | 332
Prostatic Neoplasms 3 | 471
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
esophageal adenocarcinoma 3 | 737
fibroadenoma 3 | 557
gastric cancer 3 | 430
gastric carcinoma 3 | 832
primary Sjogren syndrome 3 | 789
primary pancreatic ductal adenocarcinoma 3 | 1,271
spina bifida 3 | 1,064
tuberculosis and treatment for 6 months 3 | 686

Tissue

Digestive Tract 65 | 18,473
Female tissues 65 | 18,647
Nervous System 65 | 18,561
Urinary Tract 65 | 18,444
Blood and immune system 64 | 17,995
Cardiovascular System 64 | 17,958
Endocrine System 64 | 18,512
Liver and Pancreas 64 | 18,136
Male tissues 64 | 17,969
Respiratory system 64 | 17,484
Skin and soft tissues 64 | 18,115

Target Family

Non-IDG 34 | 11,971
Enzyme 28 | 4,146
Kinase 2 | 634
TF/Epigenetic 2 | 38
GPCR 1 | 406
Transporter 1 | 473

Compartment GO Term

Chloroplast 68 | 68
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytochrome b MT-CYB Tbio Non-IDG -3.74473 5676.0 122
60S ribosomal protein L32 RPL32 Tbio Non-IDG -2.15191 130.7 62
Lactoperoxidase LPO Tbio Enzyme -2.69742 442.5 160
10 kDa heat shock protein, mitochondrial HSPE1 Tbio Non-IDG -3.00667 987.9 390
60S ribosomal protein L14 RPL14 Tbio Non-IDG -1.67525 43.3 139
Glutathione reductase, mitochondrial GSR Tclin Enzyme -2.97339 830.6 224
60S ribosomal protein L22 RPL22 Tbio Non-IDG -2.11379 126.6 127
Glycogen phosphorylase, brain form PYGB Tbio Enzyme -1.96208 92.3 345
Glycogen phosphorylase, muscle form PYGM Tchem Enzyme -2.22583 154.4 185
40S ribosomal protein S11 RPS11 Tbio Non-IDG -1.37090 22.7 138