Development Level

Tbio 29 | 11,445
Tclin 21 | 613
Tchem 9 | 1,598
Tdark 4 | 6,588

Collection

Ion Channel: IDG Consortium (T... 19 | 99

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal heart morphology 1 | 162
abnormal testis morphology 1 | 43
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
increased circulating aspartat... 1 | 15
increased circulating creatine... 1 | 5
increased fasted circulating g... 1 | 76
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
preweaning lethality, complete... 1 | 979
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 48 | 11,493
medulloblastoma, large-cell 27 | 6,241
psoriasis 25 | 6,694
glioblastoma 23 | 5,792
atypical teratoid / rhabdoid tumor 22 | 5,112
ependymoma 21 | 4,679
osteosarcoma 21 | 7,950
ovarian cancer 20 | 8,520
Epilepsy 19 | 792
oligodendroglioma 19 | 2,850
General anesthesia 18 | 53
lung carcinoma 18 | 2,843
adult high grade glioma 17 | 3,801
primitive neuroectodermal tumor 17 | 3,035
Anxiety 16 | 136
Astrocytoma, Pilocytic 16 | 3,081
Insomnia 16 | 20
Kidney cancer 16 | 2,613
Tonic-clonic epilepsy 16 | 47
astrocytic glioma 16 | 2,597
lung cancer 15 | 4,740
group 3 medulloblastoma 14 | 4,104
malignant mesothelioma 14 | 3,232
Alcoholic Intoxication, Chronic 13 | 289
Breast cancer 13 | 3,578
Sedation as Adjunct to Anesthesia 13 | 15
cystic fibrosis 13 | 1,696
Autosomal recessive predisposition 12 | 1,442
Schizophrenia 11 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
pancreatic cancer 11 | 2,398
pituitary cancer 11 | 1,972
subependymal giant cell astrocytoma 11 | 2,287
Autistic Disorder 10 | 364
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
lung adenocarcinoma 10 | 2,716
Alcohol dependence 9 | 107
Bipolar Disorder 9 | 666
Intellectual disability 9 | 1,016
Panic disorder 9 | 61
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
Alcohol withdrawal delirium 8 | 11
Alcohol withdrawal syndrome 8 | 20
Benzodiazepine Induced Sedation 8 | 8
Benzodiazepine Maintained Anesthesia 8 | 8
Benzodiazepine Toxicity 8 | 8
Dent disease 8 | 18
Dull intelligence 8 | 645
Induce Anterograde Amnesia 8 | 9
Local anesthesia 8 | 40
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Pick disease 8 | 1,894
Poor school performance 8 | 645
Preoperative Anxiety 8 | 9
Sedation 8 | 11
Sedation in Intubated Patients 8 | 8
Spasticity 8 | 26
Status Epilepticus 8 | 98
Tetanus 8 | 68
group 4 medulloblastoma 8 | 1,855
interstitial cystitis 8 | 2,312
Anxiety associated with Menopause 7 | 7
Conscious sedation 7 | 10
Feeling agitated 7 | 7
Generalized anxiety disorder 7 | 29
Irritable bowel syndrome 7 | 60
Mixed anxiety and depressive disorder 7 | 12
Partial Epilepsy Treatment Adjunct 7 | 16
Peptic Ulcer 7 | 27
Pre-Op Apprehension 7 | 10
Severe Insomnia 7 | 7
Severe anxiety (panic) 7 | 7
active Crohn's disease 7 | 922
ductal carcinoma in situ 7 | 1,745
nasopharyngeal carcinoma 7 | 1,058
non primary Sjogren syndrome sicca 7 | 891
non-small cell lung cancer 7 | 2,890
ulcerative colitis 7 | 1,819
Initial insomnia 6 | 8
Muscle hypotonia 6 | 571
Nephrolithiasis 6 | 56
Pain with Tension and Anxiety 6 | 6
Schizoaffective Disorder 6 | 55
breast carcinoma 6 | 1,638
invasive ductal carcinoma 6 | 2,951
Bartter disease 5 | 13
Decreased tendon reflex 5 | 122
Disorders of initiating and maintaining sleep 5 | 8
Failure to gain weight 5 | 365
Mood Disorders 5 | 184
Osteopetrosis 5 | 43
Pediatric failure to thrive 5 | 365
Sensorineural Hearing Loss (disorder) 5 | 284
esophageal adenocarcinoma 5 | 737
adrenocortical carcinoma 4 | 1,428
colon cancer 4 | 1,478
gastric carcinoma 4 | 807
progressive supranuclear palsy 4 | 676

Tissue

Endocrine System 62 | 18,159
Nervous System 59 | 16,725
Digestive Tract 58 | 17,369
Female tissues 58 | 17,400
Skin and soft tissues 58 | 17,230
Blood and immune system 56 | 16,909
Male tissues 54 | 17,142
Liver and Pancreas 50 | 16,750
Urinary Tract 50 | 16,678
Respiratory system 44 | 16,393
Cardiovascular System 41 | 15,192

Target Family

Ion Channel 55 | 344
Non-IDG 7 | 12,091
Enzyme 1 | 4,145

Compartment GO Term

Chloride channel complex 63 | 63
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glycine--tRNA ligase GARS Tbio Enzyme -2.62899 412.8 178
Anoctamin-10 ANO10 Tbio Non-IDG -1.22069 14.6 54
Chloride intracellular channel protein 3 CLIC3 Tbio Ion Channel -1.01996 11.1 180
Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 Tbio Ion Channel -1.74365 53.9 92
Gamma-aminobutyric acid receptor subunit beta-3 GABRB3 Tclin Ion Channel -2.13205 136.0 202
Protein tweety homolog 2 TTYH2 Tdark Ion Channel -0.58358 3.90 19
Chloride intracellular channel protein 6 CLIC6 Tbio Ion Channel -1.04574 11.7 164
Bestrophin-1 BEST1 Tbio Ion Channel -2.69241 478.6 145
Gamma-aminobutyric acid receptor subunit alpha-1 GABRA1 Tclin Ion Channel -1.79984 58.4 301
H(+)/Cl(-) exchange transporter 4 CLCN4 Tchem Ion Channel -1.51383 32.8 132