Development Level

Tbio 430 | 10,625
Tdark 162 | 7,003
Tchem 75 | 1,890
Tclin 9 | 602

Collection

Kinase: IDG Consortium (Targets) 9 | 125
Kinase: IDG Consortium (Complete/Control) 7 | 37
GPCR: IDG Consortium (Targets) 1 | 128
Ion Channel: IDG Consortium (Targets) 1 | 102

IMPC Phenotype

preweaning lethality, complete... 39 | 633
decreased lean body mass 11 | 195
preweaning lethality, incomple... 11 | 260
decreased bone mineral content 10 | 157
decreased total body fat amoun... 10 | 186
embryonic lethality prior to t... 10 | 187
decreased body weight 9 | 174
abnormal behavior 8 | 226
hyperactivity 8 | 108
hypoactivity 8 | 89
decreased bone mineral density 7 | 126
embryonic lethality prior to o... 7 | 148
improved glucose tolerance 6 | 56
increased bone mineral content 6 | 92
increased mean corpuscular hem... 6 | 93
increased mean corpuscular vol... 6 | 91
increased or absent threshold ... 6 | 128
abnormal bone structure 5 | 131
decreased body length 5 | 108
decreased circulating choleste... 5 | 85
increased circulating alkaline... 5 | 119
increased lean body mass 5 | 107
abnormal embryo size 4 | 112
abnormal head morphology 4 | 10
abnormal lens morphology 4 | 73
decreased blood urea nitrogen ... 4 | 31
decreased circulating serum al... 4 | 79
decreased lumbar vertebrae num... 4 | 62
increased circulating choleste... 4 | 53
increased exploration in new e... 4 | 56
increased fasted circulating g... 4 | 68
increased grip strength 4 | 83
increased leukocyte cell numbe... 4 | 37
increased sacral vertebrae num... 4 | 62
increased startle reflex 4 | 38
male infertility 4 | 62
abnormal QRS complex 3 | 25
abnormal behavioral response t... 3 | 52
abnormal bone mineralization 3 | 55
abnormal kidney morphology 3 | 30
abnormal limb bud morphology 3 | 15
abnormal retina morphology 3 | 100
abnormal spleen morphology 3 | 36
abnormal startle reflex 3 | 14
abnormal tail morphology 3 | 17
decreased basophil cell number 3 | 11
decreased circulating HDL chol... 3 | 77
decreased circulating glucose ... 3 | 121
decreased circulating insulin ... 3 | 75
decreased circulating total pr... 3 | 41
decreased grip strength 3 | 123
decreased neutrophil cell numb... 3 | 37
hydrops fetalis 3 | 22
impaired glucose tolerance 3 | 52
increased bone mineral density 3 | 52
increased circulating HDL chol... 3 | 63
increased circulating LDL chol... 3 | 15
prenatal lethality prior to he... 3 | 64
abnormal coat- hair morphology 2 | 18
abnormal cranium morphology 2 | 32
abnormal embryo turning 2 | 15
abnormal humerus morphology 2 | 11
abnormal joint morphology 2 | 14
abnormal response to tactile s... 2 | 16
abnormal retinal blood vessel ... 2 | 18
abnormal sleep behavior 2 | 63
abnormal tail movements 2 | 12
abnormal testis morphology 2 | 30
cataract 2 | 26
convulsive seizures 2 | 11
decreased circulating bilirubi... 2 | 14
decreased circulating calcium ... 2 | 33
decreased circulating triglyce... 2 | 83
decreased hematocrit 2 | 25
decreased leukocyte cell numbe... 2 | 54
decreased prepulse inhibition 2 | 52
decreased red blood cell distr... 2 | 11
decreased startle reflex 2 | 48
edema 2 | 11
embryonic growth retardation 2 | 28
hemorrhage 2 | 12
immune system phenotype 2 | 17
increased NK cell number 2 | 19
increased blood urea nitrogen ... 2 | 44
increased body weight 2 | 42
increased circulating fructosa... 2 | 11
increased circulating glucose ... 2 | 16
increased circulating iron lev... 2 | 25
increased circulating serum al... 2 | 25
increased circulating sodium l... 2 | 71
increased hematocrit 2 | 36
increased mean corpuscular hem... 2 | 25
increased prepulse inhibition 2 | 21
increased total body fat amoun... 2 | 57
short tibia 2 | 82
small testis 2 | 37
vertebral fusion 2 | 23
abnormal heart looping 1 | 2
abnormal heart morphology 1 | 51
abnormal neural tube morpholog... 1 | 8

Disease

ovarian cancer 376 | 8,491
osteosarcoma 337 | 7,933
medulloblastoma, large-cell 280 | 6,234
glioblastoma 248 | 5,572
psoriasis 237 | 6,685
atypical teratoid / rhabdoid tumor 193 | 4,369
lung cancer 185 | 4,473
primitive neuroectodermal tumor 158 | 3,031
Breast cancer 152 | 3,098
malignant mesothelioma 150 | 3,163
intraductal papillary-mucinous neoplasm (IPMN) 140 | 3,289
pediatric high grade glioma 138 | 2,712
group 3 medulloblastoma 127 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 125 | 2,988
non-small cell lung cancer 123 | 2,798
oligodendroglioma 121 | 2,849
invasive ductal carcinoma 117 | 2,950
ependymoma 106 | 2,514
Carcinoma 105 | 2,147
pilocytic astrocytoma 102 | 3,086
posterior fossa group B ependymoma 96 | 1,530
Pick disease 94 | 1,893
Cancer 93 | 2,346
lung adenocarcinoma 92 | 2,714
intraductal papillary-mucinous adenoma (IPMA) 88 | 2,956
lung carcinoma 87 | 2,844
adrenocortical carcinoma 86 | 1,427
astrocytic glioma 84 | 2,241
pancreatic cancer 83 | 2,300
subependymal giant cell astrocytoma 82 | 2,287
ductal carcinoma in situ 81 | 1,745
colon cancer 75 | 1,475
adult high grade glioma 74 | 2,148
sonic hedgehog group medulloblastoma 72 | 1,482
ulcerative colitis 69 | 2,087
group 4 medulloblastoma 68 | 1,875
interstitial cystitis 68 | 2,299
breast carcinoma 67 | 1,614
posterior fossa group A ependymoma 65 | 1,511
nasopharyngeal carcinoma 63 | 1,056
Multiple myeloma 62 | 1,327
medulloblastoma 62 | 1,524
astrocytoma 60 | 1,493
atypical teratoid/rhabdoid tumor 60 | 1,095
pancreatic ductal adenocarcinoma liver metastasis 59 | 1,795
pituitary cancer 55 | 1,972
Atopic dermatitis 52 | 944
acute quadriplegic myopathy 50 | 1,157
Rheumatoid Arthritis 48 | 1,170
tuberculosis 48 | 1,563
diabetes mellitus 46 | 1,663
cystic fibrosis 44 | 1,670
juvenile dermatomyositis 43 | 1,189
tuberculosis and treatment for 6 months 43 | 686
Intellectual disability 40 | 573
chronic rhinosinusitis 40 | 512
dermatomyositis 40 | 966
active Crohn's disease 38 | 918
Waldenstrons macroglobulinemia 37 | 764
Endometriosis 36 | 535
non primary Sjogren syndrome sicca 36 | 840
primary pancreatic ductal adenocarcinoma 36 | 1,271
progressive supranuclear palsy 36 | 674
Microcephaly 31 | 149
spina bifida 30 | 1,064
Amyotrophic Lateral Sclerosis 29 | 432
Obesity 29 | 616
hepatocellular carcinoma 29 | 550
esophageal adenocarcinoma 28 | 737
acute myeloid leukemia 27 | 785
gastric carcinoma 27 | 832
Ciliopathy 26 | 57
IGA Glomerulonephritis 26 | 454
pancreatic carcinoma 26 | 567
Joubert syndrome 25 | 62
Neurodegenerative disease 25 | 383
cutaneous lupus erythematosus 25 | 1,056
primary Sjogren syndrome 25 | 788
Nephronophthisis 24 | 74
Polydactyly 24 | 93
gastric cancer 24 | 436
Alzheimer's disease 22 | 644
Mammary Neoplasms 21 | 410
Retinitis pigmentosa 21 | 156
aldosterone-producing adenoma 21 | 664
Prostatic Neoplasms 20 | 471
active ulcerative colitis 20 | 477
fibroadenoma 20 | 557
Bardet-Biedl Syndrome 19 | 40
Schizophrenia 19 | 503
cystic fibrosis and chronic rhinosinusitis 19 | 213
Down syndrome 18 | 548
Meckel syndrome 17 | 48
Asphyxiating thoracic dystrophy 16 | 34
Crohn's disease 16 | 304
non-small cell lung carcinoma 16 | 413
Peripheral Neuropathy 15 | 303
hereditary spastic paraplegia 15 | 313
glioblastoma multiforme 14 | 347
tuberculosis and treatment for 3 months 14 | 327

Tissue

Endocrine System 665 | 18,511
Digestive Tract 664 | 18,472
Female tissues 664 | 18,646
Nervous System 664 | 18,560
Liver and Pancreas 663 | 18,135
Urinary Tract 663 | 18,443
Cardiovascular System 662 | 17,957
Blood and immune system 661 | 17,994
Male tissues 660 | 17,968
Skin and soft tissues 660 | 18,114
Respiratory system 655 | 17,483

Target Family

Non-IDG 471 | 11,969
Enzyme 112 | 4,146
Kinase 49 | 634
Transcription Factor 32 | 1,400
Epigenetic 5 | 242
Transporter 4 | 473
Ion Channel 2 | 341
GPCR 1 | 408

Compartment GO Term

Centrosome 676 | 676
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.29669 19.6 50
Huntingtin HTT Tchem Non-IDG -3.32908 2140.8 521
HAUS augmin-like complex subunit 8 HAUS8 Tbio Non-IDG 1.00 0.07 117
T-complex protein 1 subunit alpha TCP1 Tbio Non-IDG -2.24310 169.4 383
Paired box protein Pax-2 PAX2 Tbio Transcription Factor -2.66256 471.8 306
HAUS augmin-like complex subunit 7 HAUS7 Tbio Non-IDG -0.21560 1.53 128
Trichoplein keratin filament-binding protein TCHP Tbio Non-IDG -2.30520 126.7 92
Zinc finger and BTB domain-containing protein 24 ZBTB24 Tbio Transcription Factor -0.85019 8.70 94
HAUS augmin-like complex subunit 2 HAUS2 Tdark Non-IDG 1.15 0.07 35
Monocarboxylate transporter 1 SLC16A1 Tchem Transporter -2.42636 263.7 235