Development Level

Tbio 477 | 11,445
Tdark 146 | 6,588
Tchem 65 | 1,598
Tclin 8 | 613

Collection

RFA-RM-18-021 10 | 328
Kinase: IDG Consortium (Target... 8 | 125
Kinase: IDG Consortium (Comple... 5 | 37
GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 64 | 979
preweaning lethality, incomple... 26 | 499
embryonic lethality prior to t... 15 | 278
abnormal behavior 14 | 298
abnormal embryo size 14 | 220
embryonic lethality prior to o... 11 | 239
hypoactivity 11 | 132
decreased total body fat amoun... 10 | 207
decreased bone mineral content 9 | 151
decreased lean body mass 9 | 135
male infertility 9 | 123
decreased body length 8 | 101
decreased body weight 8 | 161
decreased vertical activity 8 | 208
abnormal heart morphology 7 | 162
edema 7 | 59
impaired glucose tolerance 7 | 75
increased bone mineral density 7 | 72
increased lean body mass 7 | 172
prenatal lethality prior to he... 7 | 87
abnormal behavioral response t... 6 | 66
decreased bone mineral density 6 | 126
decreased circulating choleste... 6 | 93
decreased grip strength 6 | 116
embryonic growth retardation 6 | 106
enlarged heart 6 | 210
hyperactivity 6 | 148
improved glucose tolerance 6 | 79
increased bone mineral content 6 | 108
increased fasted circulating g... 6 | 76
increased startle reflex 6 | 112
abnormal bone structure 5 | 187
abnormal kidney morphology 5 | 65
decreased circulating glucose ... 5 | 126
decreased red blood cell distr... 5 | 41
increased circulating alkaline... 5 | 122
increased total body fat amoun... 5 | 134
small testis 5 | 58
abnormal craniofacial morpholo... 4 | 33
abnormal head morphology 4 | 10
abnormal joint morphology 4 | 23
abnormal lens morphology 4 | 81
abnormal spleen morphology 4 | 55
abnormal tail morphology 4 | 25
cataract 4 | 92
decreased circulating serum al... 4 | 82
increased circulating HDL chol... 4 | 80
increased mean corpuscular vol... 4 | 92
increased or absent threshold ... 4 | 101
short tibia 4 | 97
small superior vagus ganglion 4 | 74
abnormal cranium morphology 3 | 36
abnormal embryo turning 3 | 31
abnormal humerus morphology 3 | 11
abnormal limb morphology 3 | 13
abnormal locomotor behavior 3 | 24
abnormal retina morphology 3 | 71
abnormal retinal blood vessel ... 3 | 26
abnormal retinal vasculature m... 3 | 27
abnormal seminal vesicle morph... 3 | 114
abnormal sleep behavior 3 | 70
abnormal startle reflex 3 | 15
abnormal testis morphology 3 | 43
cardiovascular system phenotyp... 3 | 36
decreased circulating HDL chol... 3 | 68
decreased circulating insulin ... 3 | 76
decreased circulating total pr... 3 | 49
decreased leukocyte cell numbe... 3 | 73
decreased neutrophil cell numb... 3 | 42
decreased startle reflex 3 | 75
female infertility 3 | 60
hemorrhage 3 | 23
increased body length 3 | 32
increased circulating sodium l... 3 | 71
increased mean corpuscular hem... 3 | 96
prenatal lethality 3 | 28
prolonged QT interval 3 | 38
prolonged ST segment 3 | 36
tremors 3 | 39
abnormal body wall morphology 2 | 9
abnormal gait 2 | 69
abnormal lung morphology 2 | 26
abnormal pancreas morphology 2 | 13
abnormal placenta size 2 | 20
abnormal skin coloration 2 | 25
convulsive seizures 2 | 13
decreased caudal vertebrae num... 2 | 53
decreased circulating bilirubi... 2 | 19
decreased circulating calcium ... 2 | 36
decreased circulating potassiu... 2 | 20
decreased circulating triglyce... 2 | 79
decreased fasted circulating g... 2 | 65
decreased hematocrit 2 | 46
enlarged spleen 2 | 41
increased circulating chloride... 2 | 41
increased circulating choleste... 2 | 66
increased hematocrit 2 | 46
increased prepulse inhibition 2 | 32
microphthalmia 2 | 26
vertebral fusion 2 | 23

Disease

Carcinoma 491 | 11,493
ovarian cancer 387 | 8,520
osteosarcoma 346 | 7,950
medulloblastoma, large-cell 283 | 6,241
glioblastoma 260 | 5,792
atypical teratoid / rhabdoid tumor 238 | 5,112
psoriasis 238 | 6,694
ependymoma 223 | 4,679
group 3 medulloblastoma 212 | 4,104
lung cancer 201 | 4,740
Breast cancer 168 | 3,578
adult high grade glioma 164 | 3,801
malignant mesothelioma 159 | 3,232
primitive neuroectodermal tumor 155 | 3,035
intraductal papillary-mucinous neoplasm (IPMN) 144 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 128 | 2,989
Kidney cancer 126 | 2,613
non-small cell lung cancer 125 | 2,890
oligodendroglioma 118 | 2,850
invasive ductal carcinoma 116 | 2,951
Astrocytoma, Pilocytic 105 | 3,081
Cancer 98 | 2,499
lung adenocarcinoma 94 | 2,716
intraductal papillary-mucinous adenoma (IPMA) 93 | 2,955
Pick disease 92 | 1,894
astrocytic glioma 92 | 2,597
lung carcinoma 91 | 2,843
adrenocortical carcinoma 87 | 1,428
pancreatic cancer 83 | 2,398
ductal carcinoma in situ 82 | 1,745
subependymal giant cell astrocytoma 80 | 2,287
Autosomal recessive predisposition 78 | 1,442
Intellectual disability 77 | 1,016
breast carcinoma 73 | 1,638
colon cancer 71 | 1,478
interstitial cystitis 71 | 2,312
group 4 medulloblastoma 70 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 65 | 1,962
Multiple myeloma 64 | 1,332
tuberculosis 63 | 2,010
nasopharyngeal carcinoma 61 | 1,058
ulcerative colitis 61 | 1,819
diabetes mellitus 54 | 1,728
Atopic dermatitis 53 | 952
Dull intelligence 53 | 645
Low intelligence 53 | 645
Mental Retardation 53 | 645
Mental deficiency 53 | 645
Poor school performance 53 | 645
pituitary cancer 53 | 1,972
astrocytoma 52 | 1,146
pediatric high grade glioma 50 | 1,064
acute quadriplegic myopathy 49 | 1,158
cystic fibrosis 47 | 1,696
Rheumatoid arthritis 46 | 1,191
juvenile dermatomyositis 44 | 1,187
Schizophrenia 42 | 1,160
dermatomyositis 42 | 966
Cognitive delay 41 | 608
Global developmental delay 41 | 608
Mental and motor retardation 41 | 608
chronic rhinosinusitis 41 | 512
Short stature 40 | 531
active Crohn's disease 40 | 922
Endometriosis 38 | 540
Waldenstrons macroglobulinemia 37 | 765
non primary Sjogren syndrome sicca 37 | 891
progressive supranuclear palsy 36 | 676
Obesity 35 | 678
spina bifida 35 | 1,074
tuberculosis and treatment for 6 months 34 | 409
Small head 33 | 374
primary pancreatic ductal adenocarcinoma 33 | 1,109
Microcephaly 32 | 166
medulloblastoma 32 | 720
Ciliopathy 31 | 71
posterior fossa group B ependymoma 30 | 416
Amyotrophic lateral sclerosis 29 | 451
Nystagmus 29 | 317
Polydactyly 29 | 107
active ulcerative colitis 29 | 764
hepatocellular carcinoma 29 | 547
Epilepsy 28 | 792
esophageal adenocarcinoma 28 | 737
Neurodegenerative disease 27 | 414
gastric cancer 27 | 459
Joubert syndrome 26 | 66
Liver cancer 26 | 604
Retinitis Pigmentosa 26 | 226
acute myeloid leukemia 26 | 783
cutaneous lupus erythematosus 26 | 1,057
gastric carcinoma 25 | 807
Alzheimer's disease 24 | 658
Liver Cirrhosis, Experimental 24 | 769
Nephronophthisis 24 | 80
Seizures 24 | 596
primary Sjogren syndrome 24 | 735
Bardet-Biedl syndrome 22 | 51
Bipolar Disorder 22 | 666
pancreatic carcinoma 22 | 562

Tissue

Endocrine System 682 | 18,159
Male tissues 678 | 17,142
Digestive Tract 675 | 17,369
Female tissues 675 | 17,400
Blood and immune system 674 | 16,909
Skin and soft tissues 674 | 17,230
Liver and Pancreas 670 | 16,750
Urinary Tract 669 | 16,678
Respiratory system 668 | 16,393
Nervous System 666 | 16,725
Cardiovascular System 642 | 15,192

Target Family

Non-IDG 489 | 12,091
Enzyme 114 | 4,145
Kinase 46 | 634
Transcription Factor 32 | 1,400
Epigenetic 7 | 242
Ion Channel 4 | 344
Transporter 3 | 473
GPCR 1 | 408

Compartment GO Term

Centrosome 696 | 696
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Kinesin-like protein KIF25 KIF25 Tbio Non-IDG -0.75019 5.59 191
Nck-associated protein 5-like NCKAP5L Tdark Non-IDG -0.22123 2.83 11
RNA polymerase II subunit A C-terminal domain phosphatase CTDP1 Tbio Enzyme -1.88697 80.7 113
Rab-3A-interacting protein RAB3IP Tbio Non-IDG -1.03500 11.6 89
CAP-Gly domain-containing linker protein 1 CLIP1 Tbio Non-IDG -2.54943 343.7 221
Nuclear mitotic apparatus protein 1 NUMA1 Tbio Non-IDG -2.76544 575.8 235
Protein NLRC5 NLRC5 Tbio Non-IDG -1.74276 63.6 44
Cullin-7 CUL7 Tbio Non-IDG -1.49747 38.0 139
Protocadherin gamma-A3 PCDHGA3 Tbio Non-IDG -0.38917 3.38 181
NEDD4-binding protein 2 N4BP2 Tbio Non-IDG -0.54327 3.39 19