Development Level

Tbio 325 | 10,625
Tdark 78 | 7,003
Tchem 61 | 1,890
Tclin 9 | 602

Collection

Eligible Kinase Proteins 7 | 134

IMPC Term

preweaning lethality, complete... 31 | 633
decreased lean body mass 10 | 195
decreased bone mineral content 9 | 157
decreased body weight 8 | 174
decreased total body fat amoun... 8 | 186
embryonic lethality prior to t... 8 | 187
preweaning lethality, incomple... 8 | 260
decreased bone mineral density 6 | 126
increased or absent threshold ... 6 | 128
abnormal behavior 5 | 226
embryonic lethality prior to o... 5 | 148
hyperactivity 5 | 108
hypoactivity 5 | 89
increased circulating alkaline... 5 | 119
increased mean corpuscular hem... 5 | 93
abnormal bone structure 4 | 131
abnormal embryo size 4 | 112
abnormal head morphology 4 | 10
decreased body length 4 | 108
decreased circulating choleste... 4 | 85
decreased lumbar vertebrae num... 4 | 62
improved glucose tolerance 4 | 56
increased grip strength 4 | 83
increased lean body mass 4 | 107
increased leukocyte cell numbe... 4 | 37
increased mean corpuscular vol... 4 | 91
increased sacral vertebrae num... 4 | 62
abnormal kidney morphology 3 | 30
abnormal lens morphology 3 | 73
abnormal limb bud morphology 3 | 15
abnormal spleen morphology 3 | 36
abnormal tail morphology 3 | 17
decreased basophil cell number 3 | 11
decreased circulating glucose ... 3 | 121
decreased circulating serum al... 3 | 79
hydrops fetalis 3 | 22
increased bone mineral content 3 | 92
increased bone mineral density 3 | 52
increased circulating choleste... 3 | 53
increased exploration in new e... 3 | 56
prenatal lethality prior to he... 3 | 64
abnormal bone mineralization 2 | 55
abnormal coat/ hair morphology 2 | 18
abnormal cranium morphology 2 | 32
abnormal embryo turning 2 | 15
abnormal humerus morphology 2 | 11
abnormal joint morphology 2 | 14
abnormal startle reflex 2 | 14
abnormal tail movements 2 | 12
abnormal testis morphology 2 | 30
cataract 2 | 26
decreased circulating HDL chol... 2 | 77
decreased circulating calcium ... 2 | 33
decreased circulating total pr... 2 | 41
decreased grip strength 2 | 123
decreased hematocrit 2 | 25
edema 2 | 11
embryonic growth retardation 2 | 28
hemorrhage 2 | 12
immune system phenotype 2 | 17
impaired glucose tolerance 2 | 52
increased NK cell number 2 | 19
increased body weight 2 | 42
increased circulating HDL chol... 2 | 63
increased circulating LDL chol... 2 | 15
increased circulating glucose ... 2 | 16
increased circulating iron lev... 2 | 25
increased fasted circulating g... 2 | 68
increased hematocrit 2 | 36
increased mean corpuscular hem... 2 | 25
increased prepulse inhibition 2 | 21
increased startle reflex 2 | 38
increased total body fat amoun... 2 | 57
short tibia 2 | 82
small testis 2 | 37
vertebral fusion 2 | 23
abnormal behavioral response t... 1 | 52
abnormal body wall morphology 1 | 7
abnormal heart looping 1 | 2
abnormal heart morphology 1 | 51
abnormal neural tube closure 1 | 37
abnormal neural tube morpholog... 1 | 8
abnormal rib morphology 1 | 28
abnormal skin morphology 1 | 23
absent pinna reflex 1 | 21
convulsive seizures 1 | 11
corneal opacity 1 | 25
decreased CD4-positive, alpha ... 1 | 19
decreased blood urea nitrogen ... 1 | 31
decreased circulating magnesiu... 1 | 11
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased exploration in new e... 1 | 9
decreased heart weight 1 | 44
decreased red blood cell distr... 1 | 11
enlarged spleen 1 | 26
increased circulating creatini... 1 | 29
straub tail 1 | 26

Disease

ovarian cancer 280 | 8,484
osteosarcoma 247 | 7,933
medulloblastoma, large-cell 205 | 6,234
psoriasis 179 | 6,685
glioblastoma 173 | 5,572
atypical teratoid / rhabdoid tumor 142 | 4,369
lung cancer 142 | 4,466
primitive neuroectodermal tumor 124 | 3,031
Breast cancer 114 | 3,094
malignant mesothelioma 110 | 3,162
group 3 medulloblastoma 106 | 2,254
intraductal papillary-mucinous neoplasm (IPMN) 103 | 3,289
pediatric high grade glioma 97 | 2,712
intraductal papillary-mucinous carcinoma (IPMC) 89 | 2,988
non-small cell lung cancer 87 | 2,798
invasive ductal carcinoma 85 | 2,950
oligodendroglioma 85 | 2,849
Carcinoma 77 | 2,147
posterior fossa group B ependymoma 76 | 1,530
Cancer 74 | 2,346
ependymoma 74 | 2,514
Pick disease 71 | 1,893
adrenocortical carcinoma 70 | 1,427
lung adenocarcinoma 69 | 2,713
pancreatic cancer 65 | 2,300
astrocytic glioma 61 | 2,241
colon cancer 60 | 1,475
ductal carcinoma in situ 58 | 1,745
pilocytic astrocytoma 58 | 3,086
intraductal papillary-mucinous adenoma (IPMA) 57 | 2,956
subependymal giant cell astrocytoma 53 | 2,287
lung carcinoma 52 | 2,844
adult high grade glioma 50 | 2,148
breast carcinoma 50 | 1,614
sonic hedgehog group medulloblastoma 50 | 1,482
posterior fossa group A ependymoma 48 | 1,511
nasopharyngeal carcinoma 47 | 1,056
group 4 medulloblastoma 45 | 1,875
ulcerative colitis 45 | 2,087
atypical teratoid/rhabdoid tumor 44 | 1,095
Multiple myeloma 43 | 1,327
medulloblastoma 43 | 1,524
astrocytoma 42 | 1,493
pituitary cancer 40 | 1,972
acute quadriplegic myopathy 39 | 1,157
Intellectual disability 38 | 573
interstitial cystitis 38 | 2,299
tuberculosis 38 | 1,557
Atopic dermatitis 37 | 944
diabetes mellitus 37 | 1,663
pancreatic ductal adenocarcinoma liver metastasis 37 | 1,795
Rheumatoid Arthritis 35 | 1,160
tuberculosis and treatment for 6 months 32 | 686
Endometriosis 31 | 535
Microcephaly 31 | 149
Waldenstrons macroglobulinemia 30 | 765
chronic rhinosinusitis 30 | 512
dermatomyositis 30 | 933
juvenile dermatomyositis 29 | 1,189
progressive supranuclear palsy 29 | 674
primary pancreatic ductal adenocarcinoma 28 | 1,271
active Crohn's disease 27 | 918
Ciliopathy 26 | 57
non primary Sjogren syndrome sicca 25 | 840
Joubert syndrome 24 | 61
Nephronophthisis 24 | 74
Polydactyly 24 | 93
Amyotrophic Lateral Sclerosis 23 | 431
IGA Glomerulonephritis 23 | 454
Obesity 22 | 616
acute myeloid leukemia 22 | 780
cystic fibrosis 22 | 1,665
spina bifida 21 | 1,064
hepatocellular carcinoma 20 | 532
pancreatic carcinoma 20 | 567
Bardet-Biedl Syndrome 19 | 40
Neurodegenerative disease 19 | 383
Prostatic Neoplasms 19 | 471
Retinitis pigmentosa 19 | 153
esophageal adenocarcinoma 19 | 737
gastric cancer 19 | 430
Mammary Neoplasms 17 | 410
Meckel syndrome 17 | 48
cutaneous lupus erythematosus 17 | 1,056
gastric carcinoma 17 | 832
primary Sjogren syndrome 17 | 789
Asphyxiating thoracic dystrophy 16 | 32
Schizophrenia 16 | 501
aldosterone-producing adenoma 16 | 664
Alzheimer's disease 13 | 644
active ulcerative colitis 13 | 477
cystic fibrosis and chronic rhinosinusitis 13 | 213
Down syndrome 12 | 548
Senior-Loken syndrome 12 | 21
hereditary spastic paraplegia 12 | 313
Crohn's disease 11 | 304
Parkinson's disease 11 | 364
Renal Cell Carcinoma 11 | 199
fibroadenoma 11 | 557
non-small cell lung carcinoma 11 | 413

Tissue

Blood and immune system 464 | 17,995
Endocrine System 464 | 18,512
Cardiovascular System 463 | 17,958
Digestive Tract 463 | 18,473
Female tissues 463 | 18,647
Liver and Pancreas 463 | 18,136
Nervous System 463 | 18,561
Male tissues 462 | 17,969
Urinary Tract 462 | 18,444
Skin and soft tissues 459 | 18,115
Respiratory system 458 | 17,484

Target Family

Non-IDG 338 | 11,971
Enzyme 74 | 4,146
Kinase 42 | 634
Transcription Factor 11 | 1,400
Epigenetic 4 | 242
Transporter 3 | 473
Ion Channel 1 | 341

Compartment GO Term

Centrosome 473 | 473
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Syntaxin-1B STX1B Tbio Non-IDG -1.74488 52.6 27
G2/mitotic-specific cyclin-B1 CCNB1 Tchem Non-IDG -3.09727 1121.4 955
Coiled-coil domain-containing protein 15 CCDC15 Tdark Non-IDG 0.00000 53
Proliferating cell nuclear antigen PCNA Tchem Non-IDG -1.10426 11.5 1277
Malate dehydrogenase, cytoplasmic MDH1 Tbio Enzyme -2.61325 409.6 244
Ankyrin repeat domain-containing protein 26 ANKRD26 Tbio Non-IDG -1.28843 22.9 87
Exocyst complex component 7 EXOC7 Tbio Non-IDG -1.72231 55.8 158
Centrosomal protein of 164 kDa CEP164 Tbio Non-IDG -0.96655 10.2 84
MAP7 domain-containing protein 3 MAP7D3 Tbio Non-IDG -0.92082 8.05 8
Bardet-Biedl syndrome 7 protein BBS7 Tbio Non-IDG -1.02867 11.1 125