Development Level

Tbio 31 | 10,625
Tdark 11 | 7,003
Tchem 1 | 1,890

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

decreased bone mineral content 2 | 157
decreased lean body mass 2 | 195
decreased total body fat amoun... 2 | 186
preweaning lethality, incomple... 2 | 260
abnormal behavioral response t... 1 | 52
abnormal bone structure 1 | 131
abnormal embryo size 1 | 112
abnormal embryo turning 1 | 15
abnormal heart left ventricle ... 1 | 20
abnormal heart looping 1 | 2
abnormal heart morphology 1 | 51
abnormal neural tube closure 1 | 37
abnormal neural tube morpholog... 1 | 8
abnormal sleep behavior 1 | 63
decreased B cell number 1 | 30
decreased body length 1 | 108
decreased bone mineral density 1 | 126
decreased effector memory CD8-... 1 | 24
decreased mature B cell number 1 | 25
embryonic growth retardation 1 | 28
embryonic lethality prior to t... 1 | 187
immune system phenotype 1 | 17
increased CD8-positive, naive ... 1 | 3
increased NK cell number 1 | 19
increased bone mineral content 1 | 92
increased circulating alkaline... 1 | 119
increased exploration in new e... 1 | 56
increased lean body mass 1 | 107
increased or absent threshold ... 1 | 128
increased plasma cell number 1 | 5
increased total body fat amoun... 1 | 57
preweaning lethality, complete... 1 | 633

Disease

ovarian cancer 24 | 8,492
osteosarcoma 18 | 7,933
posterior fossa group B ependymoma 15 | 1,530
medulloblastoma, large-cell 13 | 6,234
atypical teratoid / rhabdoid tumor 11 | 4,369
psoriasis 11 | 6,685
glioblastoma 10 | 5,572
lung cancer 10 | 4,473
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,289
Breast cancer 8 | 3,099
group 3 medulloblastoma 8 | 2,254
nasopharyngeal carcinoma 8 | 1,056
Polydactyly 7 | 93
chronic rhinosinusitis 7 | 512
malignant mesothelioma 7 | 3,163
Ciliopathy 6 | 57
Intellectual disability 6 | 573
Joubert syndrome 6 | 62
Obesity 6 | 616
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
invasive ductal carcinoma 6 | 2,950
oligodendroglioma 6 | 2,849
pilocytic astrocytoma 6 | 3,086
Bardet-Biedl Syndrome 5 | 40
Cancer 5 | 2,346
Pick disease 5 | 1,893
astrocytic glioma 5 | 2,241
colon cancer 5 | 1,475
ependymoma 5 | 2,514
lung carcinoma 5 | 2,844
medulloblastoma 5 | 1,524
non-small cell lung cancer 5 | 2,798
pediatric high grade glioma 5 | 2,712
sonic hedgehog group medulloblastoma 5 | 1,482
Bardet-Biedl syndrome 1 4 | 22
Nephronophthisis 4 | 74
adrenocortical carcinoma 4 | 1,427
astrocytoma 4 | 1,493
breast carcinoma 4 | 1,614
ductal carcinoma in situ 4 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
pituitary cancer 4 | 1,972
primitive neuroectodermal tumor 4 | 3,031
subependymal giant cell astrocytoma 4 | 2,287
Carcinoma 3 | 2,147
Cystic kidney disease 3 | 26
Microcephaly 3 | 149
Rheumatoid Arthritis 3 | 1,171
Senior-Loken syndrome 3 | 22
adult high grade glioma 3 | 2,148
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
lung adenocarcinoma 3 | 2,714
non primary Sjogren syndrome sicca 3 | 840
progressive supranuclear palsy 3 | 674
tuberculosis 3 | 1,563
ulcerative colitis 3 | 2,087
Asphyxiating thoracic dystrophy 2 | 34
Coloboma 2 | 52
Cone dystrophy 2 | 59
Drug-Induced Liver Injury 2 | 118
Endometriosis 2 | 535
Fundus dystrophy 2 | 77
Hydrolethalus syndrome 2 | 128
Joubert syndrome with orofaciodigital defect 2 | 8
Kidney disease 2 | 397
Leber congenital amaurosis 2 | 72
Meckel syndrome 2 | 48
Papillary thyroid carcinoma 2 | 37
Polycystic kidney disease 2 | 54
Primary ciliary dyskinesia 2 | 75
Renal dysplasia and retinal aplasia (disorder) 2 | 10
Retinal Degeneration 2 | 49
Schizophrenia 2 | 503
Seckel syndrome 2 | 35
active ulcerative colitis 2 | 477
atypical teratoid/rhabdoid tumor 2 | 1,095
cystic fibrosis 2 | 1,670
diabetes mellitus 2 | 1,663
interstitial cystitis 2 | 2,299
posterior fossa group A ependymoma 2 | 1,511
spina bifida 2 | 1,064
Bilateral renal hypoplasia 1 | 1
Choroid Plexus Papilloma 1 | 10
Denys-Drash syndrome 1 | 11
Eosinophilic esophagitis 1 | 31
Female Urogenital Diseases 1 | 18
Focal segmental glomerulosclerosis 7 1 | 1
Galactosemia 1 | 20
Hypermethioninemia 1 | 12
Kidney Failure, Chronic 1 | 45
Liver Failure, Acute 1 | 22
Nephrogenic adenoma 1 | 10
Nephrogenic adenoma of urinary bladder 1 | 2
Oculocerebrorenal syndrome 1 | 24
Orofaciodigital syndrome 1 | 19
Papillorenal syndrome 1 | 1
Tropical sprue 1 | 5
Tyrosinemia 1 | 12
Vesicoureteral reflux 1 | 28
Wilson disease 1 | 16

Tissue

Blood and immune system 43 | 17,995
Digestive Tract 43 | 18,473
Endocrine System 43 | 18,512
Female tissues 43 | 18,647
Liver and Pancreas 43 | 18,136
Male tissues 43 | 17,969
Nervous System 43 | 18,561
Respiratory system 43 | 17,484
Skin and soft tissues 43 | 18,115
Urinary Tract 43 | 18,444
Cardiovascular System 42 | 17,958

Target Family

Non-IDG 37 | 11,969
Enzyme 3 | 4,146
Kinase 2 | 634
Transcription Factor 1 | 1,400

Compartment GO Term

Centriolar satellite 43 | 43
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Coiled-coil domain-containing protein 38 CCDC38 Tdark Non-IDG -0.33995 1.97 115
Paired box protein Pax-2 PAX2 Tbio Transcription Factor -2.66256 471.8 306
Bardet-Biedl syndrome 4 protein BBS4 Tbio Non-IDG -1.51111 26.5 179
Progesterone-induced-blocking factor 1 PIBF1 Tbio Non-IDG -1.28327 19.9 201
Sperm-associated antigen 5 SPAG5 Tbio Non-IDG -1.66404 47.3 120
Keratin, type I cytoskeletal 18 KRT18 Tbio Non-IDG -3.03148 1010.3 1678
Centrosomal protein of 131 kDa CEP131 Tbio Non-IDG -1.75708 61.0 81
Ras-related protein Rab-8A RAB8A Tbio Enzyme -2.18942 145.2 156
Exocyst complex component 7 EXOC7 Tbio Non-IDG -1.78269 55.8 158
Centrosomal protein of 290 kDa CEP290 Tbio Non-IDG -1.98851 101.3 125