Development Level

Tbio 62 | 11,651
Tchem 9 | 1,388
Tdark 5 | 6,593
Tclin 3 | 612

IMPC Phenotype

preweaning lethality, complete... 9 | 979
preweaning lethality, incomple... 4 | 499
abnormal behavior 2 | 298
decreased red blood cell distr... 2 | 41
decreased threshold for audito... 2 | 26
embryonic growth retardation 2 | 106
increased bone mineral density 2 | 72
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal skin coloration 1 | 25
absent startle reflex 1 | 24
absent teeth 1 | 3
cardiovascular system phenotyp... 1 | 36
decreased circulating calcium ... 1 | 36
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating unsatura... 1 | 2
decreased eosinophil cell numb... 1 | 24
decreased grip strength 1 | 116
decreased large unstained cell... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
female infertility 1 | 60
hemorrhage 1 | 23
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased exploration in new e... 1 | 8
increased heart rate variabili... 1 | 7
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
tremors 1 | 39
vertebral fusion 1 | 23

Disease

Carcinoma 51 | 11,493
ovarian cancer 49 | 8,520
glioblastoma 40 | 5,792
osteosarcoma 40 | 7,950
psoriasis 36 | 6,694
medulloblastoma, large-cell 34 | 6,241
atypical teratoid / rhabdoid tumor 30 | 5,112
ependymoma 25 | 4,679
lung cancer 24 | 4,740
primitive neuroectodermal tumor 24 | 3,035
adult high grade glioma 23 | 3,801
pancreatic cancer 23 | 2,398
invasive ductal carcinoma 22 | 2,951
Autosomal recessive predisposition 21 | 1,442
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
group 3 medulloblastoma 20 | 4,104
Astrocytoma, Pilocytic 19 | 3,081
Muscular dystrophy 19 | 75
lung adenocarcinoma 19 | 2,716
colon cancer 18 | 1,478
Breast cancer 17 | 3,578
Cancer 17 | 2,499
Creatine phosphokinase serum increased 17 | 110
Elevated creatine kinase 17 | 110
Myopathy 17 | 185
Kidney cancer 16 | 2,613
non-small cell lung cancer 16 | 2,890
adrenocortical carcinoma 15 | 1,428
limb-girdle muscular dystrophy 15 | 37
malignant mesothelioma 15 | 3,232
Muscle biopsy shows dystrophic changes 14 | 39
breast carcinoma 13 | 1,638
ductal carcinoma in situ 13 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
lung carcinoma 12 | 2,843
oligodendroglioma 12 | 2,850
tuberculosis 12 | 2,010
Cardiomyopathy 11 | 116
Intellectual disability 11 | 1,016
subependymal giant cell astrocytoma 11 | 2,287
Multiple myeloma 10 | 1,332
astrocytic glioma 10 | 2,597
group 4 medulloblastoma 10 | 1,855
pediatric high grade glioma 10 | 1,064
Muscle hypotonia 9 | 571
Proximal muscle weakness 9 | 47
Proximal neurogenic muscle weakness 9 | 47
dermatomyositis 9 | 966
interstitial cystitis 9 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
primary pancreatic ductal adenocarcinoma 9 | 1,109
ulcerative colitis 9 | 1,819
Atopic dermatitis 8 | 952
Dull intelligence 8 | 645
Endometriosis 8 | 540
Epilepsy 8 | 792
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Pick disease 8 | 1,894
Poor school performance 8 | 645
Schizophrenia 8 | 1,160
acute quadriplegic myopathy 8 | 1,158
astrocytoma 8 | 1,146
juvenile dermatomyositis 8 | 1,187
Adult onset 7 | 82
Cognitive delay 7 | 608
Global developmental delay 7 | 608
Gowers sign 7 | 24
Gowers sign present 7 | 24
Highly variable severity 7 | 157
Mental and motor retardation 7 | 608
Seizures 7 | 596
Variable expressivity 7 | 157
diabetes mellitus 7 | 1,728
esophageal adenocarcinoma 7 | 737
nasopharyngeal carcinoma 7 | 1,058
pituitary cancer 7 | 1,972
progressive supranuclear palsy 7 | 676
Cardiomyopathies 6 | 110
Cataract 6 | 297
Contracture 6 | 96
Contracture of joint 6 | 93
Flexion contracture 6 | 93
Flexion contractures of joints 6 | 93
Lens Opacities 6 | 231
Liver Cirrhosis, Experimental 6 | 769
Liver cancer 6 | 604
Melanoma 6 | 711
Neoplasm Invasiveness 6 | 161
Prenatal onset 6 | 139
Skin cancer 6 | 469
cutaneous lupus erythematosus 6 | 1,057
cystic fibrosis 6 | 1,696
hereditary spastic paraplegia 6 | 318
non primary Sjogren syndrome sicca 6 | 891
Duchenne muscular dystrophy 5 | 601
Rheumatoid arthritis 5 | 1,191
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510

Tissue

Endocrine System 79 | 18,159
Blood and immune system 78 | 16,909
Digestive Tract 78 | 17,369
Skin and soft tissues 77 | 17,230
Urinary Tract 77 | 16,678
Female tissues 76 | 17,400
Nervous System 76 | 16,725
Liver and Pancreas 75 | 16,750
Male tissues 75 | 17,142
Respiratory system 75 | 16,393
Cardiovascular System 74 | 15,192

Target Family

Non-IDG 52 | 12,091
Enzyme 17 | 4,145
Kinase 6 | 634
Transcription Factor 2 | 1,400
Ion Channel 1 | 344
oGPCR 1 | 421

Compartment GO Term

Cell surface furrow 79 | 79
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.33715 23.1 275
Myosin light chain kinase, smooth muscle MYLK Tchem Kinase -2.81312 694.0 219
Fibronectin type III and SPRY domain-containing protein 1 FSD1 Tbio Non-IDG -1.38197 23.9 160
Mannose-1-phosphate guanyltransferase beta GMPPB Tbio Enzyme -1.17283 16.0 118
Pleckstrin homology domain-containing family G member 6 PLEKHG6 Tbio Non-IDG -0.56736 4.94 109
Rab11 family-interacting protein 4 RAB11FIP4 Tbio Non-IDG -0.68187 5.48 43
Ras-related protein Rab-11A RAB11A Tbio Enzyme -2.65458 432.1 352
Protein phosphatase Slingshot homolog 1 SSH1 Tbio Enzyme -1.45823 27.6 148
Ras-related protein Ral-A RALA Tbio Enzyme -2.22188 169.9 225
5-hydroxytryptamine receptor 3A HTR3A Tclin Ion Channel -3.38661 2426.7 262