Development Level

Tbio 505 | 10,625
Tchem 187 | 1,890
Tclin 86 | 602
Tdark 58 | 7,003

Collection

GPCR: IDG Consortium (Targets) 5 | 128

IMPC Phenotype

preweaning lethality, complete... 27 | 633
preweaning lethality, incomple... 17 | 260
decreased grip strength 12 | 123
embryonic lethality prior to t... 11 | 187
abnormal behavior 10 | 226
enlarged heart 9 | 111
decreased total body fat amoun... 8 | 186
decreased lean body mass 7 | 195
embryonic lethality prior to o... 7 | 148
tremors 7 | 34
decreased body weight 6 | 174
decreased bone mineral density 6 | 126
decreased leukocyte cell numbe... 6 | 54
increased or absent threshold ... 6 | 128
abnormal bone structure 5 | 131
abnormal embryo size 5 | 112
abnormal retina morphology 5 | 100
decreased bone mineral content 5 | 157
decreased circulating choleste... 5 | 85
decreased circulating glucose ... 5 | 121
impaired glucose tolerance 5 | 52
improved glucose tolerance 5 | 56
increased circulating alkaline... 5 | 119
increased circulating sodium l... 5 | 71
increased lean body mass 5 | 107
increased total body fat amoun... 5 | 57
abnormal eye morphology 4 | 38
abnormal heart morphology 4 | 51
abnormal sleep behavior 4 | 63
decreased NK T cell number 4 | 28
decreased body length 4 | 108
decreased circulating HDL chol... 4 | 77
decreased circulating alanine ... 4 | 53
decreased circulating alkaline... 4 | 41
decreased prepulse inhibition 4 | 52
decreased startle reflex 4 | 48
hyperactivity 4 | 108
increased body weight 4 | 42
increased circulating HDL chol... 4 | 63
increased circulating choleste... 4 | 53
increased fasted circulating g... 4 | 68
increased grip strength 4 | 83
increased leukocyte cell numbe... 4 | 37
increased mean corpuscular hem... 4 | 93
increased mean corpuscular vol... 4 | 91
limb grasping 4 | 35
short tibia 4 | 82
abnormal QRS complex 3 | 25
abnormal epididymis morphology 3 | 31
abnormal gait 3 | 51
abnormal lens morphology 3 | 73
abnormal limb bud morphology 3 | 15
abnormal locomotor activation 3 | 26
abnormal retinal pigmentation 3 | 61
abnormal tooth morphology 3 | 24
abnormal vibrissa morphology 3 | 17
absent startle reflex 3 | 15
cardiovascular system phenotyp... 3 | 35
decreased circulating calcium ... 3 | 33
decreased circulating insulin ... 3 | 75
decreased fasted circulating g... 3 | 49
decreased heart weight 3 | 44
decreased mean corpuscular hem... 3 | 34
hypoactivity 3 | 89
increased bone mineral content 3 | 92
increased bone mineral density 3 | 52
increased circulating bilirubi... 3 | 16
increased heart weight 3 | 37
thrombocytopenia 3 | 46
abnormal coat appearance 2 | 25
abnormal coat-hair pigmentatio... 2 | 54
abnormal head morphology 2 | 10
abnormal heart left ventricle ... 2 | 20
abnormal skin morphology 2 | 23
abnormal spleen morphology 2 | 36
corneal opacity 2 | 25
decreased T cell number 2 | 31
decreased circulating serum al... 2 | 79
decreased circulating sodium l... 2 | 18
decreased circulating triglyce... 2 | 83
decreased eosinophil cell numb... 2 | 41
decreased hemoglobin content 2 | 53
decreased lumbar vertebrae num... 2 | 62
decreased mean corpuscular vol... 2 | 50
decreased pulmonary respirator... 2 | 4
enlarged spleen 2 | 26
enlarged stomach 2 | 2
female infertility 2 | 34
increased circulating calcium ... 2 | 32
increased circulating magnesiu... 2 | 10
increased erythrocyte cell num... 2 | 26
increased exploration in new e... 2 | 56
increased hematocrit 2 | 36
increased hemoglobin content 2 | 45
increased prepulse inhibition 2 | 21
increased sacral vertebrae num... 2 | 62
lethargy 2 | 5
prenatal lethality prior to he... 2 | 64
small testis 2 | 37
small thymus 2 | 11

Disease

Cancer 457 | 2,346
psoriasis 427 | 6,685
ovarian cancer 386 | 8,491
osteosarcoma 372 | 7,933
glioblastoma 307 | 5,572
lung cancer 307 | 4,473
medulloblastoma, large-cell 271 | 6,234
lung carcinoma 265 | 2,844
diabetes mellitus 235 | 1,663
interstitial cystitis 225 | 2,299
invasive ductal carcinoma 220 | 2,950
pilocytic astrocytoma 220 | 3,086
intraductal papillary-mucinous neoplasm (IPMN) 207 | 3,289
ulcerative colitis 207 | 2,087
malignant mesothelioma 206 | 3,163
lung adenocarcinoma 204 | 2,714
intraductal papillary-mucinous carcinoma (IPMC) 203 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 200 | 2,956
atypical teratoid / rhabdoid tumor 199 | 4,369
non-small cell lung cancer 195 | 2,798
pancreatic cancer 194 | 2,300
Breast cancer 190 | 3,098
tuberculosis 168 | 1,563
pediatric high grade glioma 163 | 2,712
Hypersensitivity reaction type II disease 162 | 235
Rheumatoid Arthritis 157 | 1,170
cystic fibrosis 157 | 1,670
Arthritis 140 | 248
subependymal giant cell astrocytoma 140 | 2,287
Carcinoma 137 | 2,147
cutaneous lupus erythematosus 133 | 1,056
Kidney disease 130 | 397
ductal carcinoma in situ 128 | 1,745
Multiple Sclerosis 127 | 498
oligodendroglioma 123 | 2,849
pituitary cancer 120 | 1,972
breast carcinoma 118 | 1,614
group 4 medulloblastoma 117 | 1,875
posterior fossa group A ependymoma 117 | 1,511
primitive neuroectodermal tumor 117 | 3,031
colon cancer 115 | 1,475
dermatomyositis 111 | 966
adrenocortical carcinoma 109 | 1,427
pancreatic ductal adenocarcinoma liver metastasis 105 | 1,795
ependymoma 104 | 2,514
primary pancreatic ductal adenocarcinoma 102 | 1,271
Human immunodeficiency virus infectious disease 100 | 129
adult high grade glioma 99 | 2,148
Liver disease 97 | 219
juvenile dermatomyositis 95 | 1,189
Anemia 93 | 252
Acquired immunodeficiency syndrome 92 | 164
Atherosclerosis 91 | 275
Ankylosing spondylitis 89 | 138
astrocytoma 89 | 1,493
Alzheimer's disease 86 | 644
Asthma 86 | 349
astrocytic glioma 85 | 2,241
esophageal adenocarcinoma 85 | 737
nasopharyngeal carcinoma 84 | 1,056
Uveitis 81 | 103
gastric carcinoma 80 | 832
Duchenne muscular dystrophy 79 | 602
primary Sjogren syndrome 78 | 788
Multiple myeloma 77 | 1,327
Dermatitis 76 | 141
Atopic dermatitis 71 | 944
Juvenile rheumatoid arthritis 71 | 105
Lung disease 71 | 136
Prostatic Neoplasms 70 | 471
Vascular disease 69 | 281
acute quadriplegic myopathy 69 | 1,157
group 3 medulloblastoma 69 | 2,254
Cerebrovascular disease 68 | 231
Coronary artery disease 68 | 240
Down syndrome 68 | 548
Heart disease 68 | 279
Mammary Neoplasms 66 | 410
active Crohn's disease 66 | 918
Hypertension 64 | 293
sonic hedgehog group medulloblastoma 64 | 1,482
Pick disease 63 | 1,893
Inflammatory bowel disease 62 | 142
Psoriatic arthritis 61 | 85
mucosa-associated lymphoid tissue lymphoma 61 | 480
posterior fossa group B ependymoma 61 | 1,530
Behcet's disease 60 | 74
Stevens-Johnson syndrome 60 | 91
Obesity 59 | 616
autosomal dominant Emery-Dreifuss muscular dystrophy 59 | 499
Endometriosis 58 | 535
Schizophrenia 58 | 503
Hepatitis B 56 | 103
spina bifida 56 | 1,064
atypical teratoid/rhabdoid tumor 54 | 1,095
medulloblastoma 54 | 1,524
Thrombocytopenia 52 | 105
IGA Glomerulonephritis 51 | 454
Stomach Neoplasms 51 | 282
non-small cell lung carcinoma 51 | 413

Tissue

Nervous System 740 | 18,560
Female tissues 739 | 18,646
Digestive Tract 736 | 18,472
Endocrine System 736 | 18,511
Urinary Tract 736 | 18,443
Liver and Pancreas 725 | 18,135
Blood and immune system 723 | 17,994
Male tissues 722 | 17,968
Respiratory system 721 | 17,483
Cardiovascular System 719 | 17,957
Skin and soft tissues 719 | 18,114

Target Family

Non-IDG 593 | 11,969
Enzyme 126 | 4,146
GPCR 36 | 408
Kinase 31 | 634
Ion Channel 19 | 341
Transporter 19 | 473
Transcription Factor 9 | 1,400
Epigenetic 1 | 242
Nuclear Receptor 1 | 48
oGPCR 1 | 421

Compartment GO Term

Cell surface 836 | 836
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.29593 203.1 88
E-selectin SELE Tchem Non-IDG -3.43650 2598.8 820
Receptor tyrosine-protein kinase erbB-2 ERBB2 Tclin Kinase -4.25806 19000.3 3336
Galectin-3 LGALS3 Tchem Non-IDG -3.33005 2249.5 911
Folate receptor alpha FOLR1 Tchem Non-IDG -2.27944 181.4 235
E3 ubiquitin-protein ligase NEDD4-like NEDD4L Tbio Enzyme -2.50001 312.7 133
CD40 ligand CD40LG Tchem Non-IDG -4.56976 36580.5 1095
Alternative prion protein PRNP Tbio Non-IDG -3.44085 5471.9 0
Complement receptor type 1 CR1 Tbio Non-IDG -3.34929 2279.9 502
Serine protease hepsin HPN Tchem Enzyme -2.46640 312.3 106