Development Level

Tbio 209 | 11,651
Tchem 34 | 1,388
Tclin 31 | 612
Tdark 18 | 6,593

Collection

GPCR: IDG Consortium (Targets) 5 | 126
RFA-RM-18-021 4 | 328
GPCR: IDG Consortium (Complete... 2 | 25
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 16 | 979
decreased body weight 9 | 161
preweaning lethality, incomple... 9 | 499
abnormal behavior 7 | 298
decreased circulating triglyce... 7 | 79
decreased grip strength 6 | 116
increased circulating alkaline... 6 | 122
increased lean body mass 6 | 172
abnormal embryo size 5 | 220
hyperactivity 5 | 148
impaired glucose tolerance 5 | 75
increased mean corpuscular hem... 5 | 96
abnormal lens morphology 4 | 81
abnormal retina morphology 4 | 71
decreased bone mineral content 4 | 151
decreased circulating choleste... 4 | 93
decreased circulating glucose ... 4 | 126
decreased circulating insulin ... 4 | 76
decreased leukocyte cell numbe... 4 | 73
embryonic growth retardation 4 | 106
embryonic lethality prior to t... 4 | 278
increased mean corpuscular vol... 4 | 92
abnormal heart morphology 3 | 162
cardiovascular system phenotyp... 3 | 36
cataract 3 | 92
decreased circulating HDL chol... 3 | 68
decreased circulating LDL chol... 3 | 38
decreased circulating alanine ... 3 | 47
decreased hemoglobin content 3 | 68
decreased total body fat amoun... 3 | 207
decreased vertical activity 3 | 208
increased blood urea nitrogen ... 3 | 48
increased circulating chloride... 3 | 41
increased fasted circulating g... 3 | 76
abnormal bone structure 2 | 187
abnormal sleep behavior 2 | 70
abnormal spleen morphology 2 | 55
abnormal urinary bladder morph... 2 | 11
abnormal whole-body plethysmog... 2 | 4
decreased T cell number 2 | 15
decreased body length 2 | 101
decreased bone mineral density 2 | 126
decreased caudal vertebrae num... 2 | 53
decreased circulating alkaline... 2 | 46
decreased circulating amylase ... 2 | 28
decreased circulating serum al... 2 | 82
decreased circulating total pr... 2 | 49
decreased heart rate variabili... 2 | 13
decreased heart weight 2 | 27
decreased mean corpuscular hem... 2 | 31
decreased mean corpuscular vol... 2 | 79
enlarged heart 2 | 210
enlarged spleen 2 | 41
hypoactivity 2 | 132
improved glucose tolerance 2 | 79
increased bone mineral density 2 | 72
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
increased circulating glucose ... 2 | 24
increased circulating total pr... 2 | 28
increased circulating triglyce... 2 | 42
increased heart rate variabili... 2 | 7
increased hematocrit 2 | 46
increased leukocyte cell numbe... 2 | 47
increased prepulse inhibition 2 | 32
increased total body fat amoun... 2 | 134
increased vertical activity 2 | 24
persistence of hyaloid vascula... 2 | 33
polycystic kidney 2 | 15
prolonged ST segment 2 | 36
abnormal cornea morphology 1 | 31
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal liver morphology 1 | 17
abnormal retinal inner nuclear... 1 | 8
abnormal seminal vesicle morph... 1 | 114
absent vibrissae 1 | 12
cystolithiasis 1 | 3
decreased IgE level 1 | 6
decreased IgG1 level 1 | 8
decreased circulating calcium ... 1 | 36
decreased circulating iron lev... 1 | 32
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
enlarged urinary bladder 1 | 8
impaired pupillary reflex 1 | 26
increased anti-nuclear antigen... 1 | 19
increased blood uric acid leve... 1 | 5
increased body weight 1 | 25
increased circulating amylase ... 1 | 25
increased circulating aspartat... 1 | 15
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
thrombocytosis 1 | 27
tremors 1 | 39
vertebral fusion 1 | 23

Disease

Carcinoma 227 | 11,493
osteosarcoma 145 | 7,950
ovarian cancer 138 | 8,520
psoriasis 113 | 6,694
medulloblastoma, large-cell 111 | 6,241
glioblastoma 107 | 5,792
ependymoma 91 | 4,679
atypical teratoid / rhabdoid tumor 87 | 5,112
lung cancer 79 | 4,740
Breast cancer 72 | 3,578
malignant mesothelioma 71 | 3,232
lung adenocarcinoma 70 | 2,716
group 3 medulloblastoma 67 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 67 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 66 | 3,291
lung carcinoma 66 | 2,843
non-small cell lung cancer 66 | 2,890
Astrocytoma, Pilocytic 65 | 3,081
pancreatic cancer 64 | 2,398
adult high grade glioma 63 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 63 | 2,989
oligodendroglioma 63 | 2,850
Cancer 60 | 2,499
invasive ductal carcinoma 60 | 2,951
interstitial cystitis 58 | 2,312
Autosomal recessive predisposition 57 | 1,442
Kidney cancer 56 | 2,613
astrocytic glioma 48 | 2,597
subependymal giant cell astrocytoma 47 | 2,287
ulcerative colitis 47 | 1,819
breast carcinoma 44 | 1,638
primitive neuroectodermal tumor 44 | 3,035
colon cancer 43 | 1,478
Intellectual disability 42 | 1,016
diabetes mellitus 40 | 1,728
ductal carcinoma in situ 39 | 1,745
pituitary cancer 39 | 1,972
cystic fibrosis 38 | 1,696
tuberculosis 37 | 2,010
Obesity 36 | 678
Pick disease 36 | 1,894
pancreatic ductal adenocarcinoma liver metastasis 35 | 1,962
adrenocortical carcinoma 32 | 1,428
Schizophrenia 30 | 1,160
Dull intelligence 29 | 645
Low intelligence 29 | 645
Mental Retardation 29 | 645
Mental deficiency 29 | 645
Poor school performance 29 | 645
Kidney disease 27 | 430
acute quadriplegic myopathy 27 | 1,158
pediatric high grade glioma 27 | 1,064
active Crohn's disease 26 | 922
group 4 medulloblastoma 26 | 1,855
spina bifida 26 | 1,074
primary pancreatic ductal adenocarcinoma 25 | 1,109
astrocytoma 24 | 1,146
cutaneous lupus erythematosus 23 | 1,057
Liver Cirrhosis, Experimental 22 | 769
Nystagmus 22 | 317
Retinitis Pigmentosa 22 | 226
active ulcerative colitis 22 | 764
Alzheimer's disease 21 | 658
Hypertension 21 | 396
Liver cancer 21 | 604
Melanoma 21 | 711
juvenile dermatomyositis 21 | 1,187
Cataract 20 | 297
nasopharyngeal carcinoma 20 | 1,058
Epilepsy 19 | 792
Sensorineural Hearing Loss (disorder) 19 | 284
nephrosclerosis 19 | 333
Bipolar Disorder 18 | 666
Down syndrome 18 | 499
Duchenne muscular dystrophy 18 | 601
Electroretinogram abnormal 18 | 95
Glaucoma 18 | 239
Skin cancer 18 | 469
fibroadenoma 18 | 559
Abnormality of retinal pigmentation 17 | 111
Cone dystrophy 17 | 71
Hypogonadism 17 | 173
Lens Opacities 17 | 231
Photodysphoria 17 | 121
Photophobia 17 | 121
Retinal pigment epithelial abnormality 17 | 111
Rheumatoid arthritis 17 | 1,191
Waldenstrons macroglobulinemia 17 | 765
gastric carcinoma 17 | 807
Cognitive delay 16 | 608
Congenital hypoplasia of penis 16 | 176
Global developmental delay 16 | 608
Hypertensive disease 16 | 292
Mental and motor retardation 16 | 608
Muscle hypotonia 16 | 571
Night Blindness 16 | 101
Optic Atrophy 16 | 242
mucosa-associated lymphoid tissue lymphoma 16 | 484
dermatomyositis 15 | 966
esophageal adenocarcinoma 15 | 737

Tissue

Endocrine System 278 | 18,159
Digestive Tract 276 | 17,369
Skin and soft tissues 271 | 17,230
Male tissues 268 | 17,142
Urinary Tract 267 | 16,678
Liver and Pancreas 264 | 16,750
Female tissues 263 | 17,400
Nervous System 263 | 16,725
Blood and immune system 259 | 16,909
Respiratory system 249 | 16,393
Cardiovascular System 226 | 15,192

Target Family

Non-IDG 153 | 12,091
Enzyme 51 | 4,145
Transporter 39 | 473
GPCR 18 | 408
Kinase 16 | 634
Ion Channel 15 | 344

Compartment GO Term

Cell projection membrane 292 | 292
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Long-wave-sensitive opsin 1 OPN1LW Tbio GPCR -2.37983 238.7 47
Serine/threonine-protein kinase PAK 1 PAK1 Tchem Kinase -2.29299 237.8 1060
Spectrin beta chain, non-erythrocytic 5 SPTBN5 Tbio Non-IDG -0.41365 2.99 32
Intelectin-1 ITLN1 Tbio Non-IDG -2.49500 337.0 194
Gastric intrinsic factor GIF Tbio Non-IDG -3.20615 1559.4 172
Integrin alpha-3 ITGA3 Tbio Non-IDG -2.08360 104.1 587
NADPH oxidase 1 NOX1 Tchem Enzyme -2.59188 397.6 233
Platelet glycoprotein 4 CD36 Tbio Non-IDG -2.63884 376.0 1155
Ezrin EZR Tbio Non-IDG -2.99865 981.3 1088
Rho GTPase-activating protein 7 DLC1 Tbio Enzyme -1.93185 106.7 137