Development Level

Tbio 180 | 10,625
Tchem 40 | 1,890
Tclin 26 | 602
Tdark 17 | 7,003

Collection

Eligible non-olfactory GPCR Proteins 5 | 143
Eligible Ion Channel Proteins 1 | 117
Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 9 | 633
decreased body weight 7 | 174
decreased total body fat amoun... 7 | 186
decreased circulating triglyce... 6 | 83
preweaning lethality, incomple... 6 | 260
decreased bone mineral density 5 | 126
decreased grip strength 5 | 123
decreased lean body mass 5 | 195
increased circulating alkaline... 5 | 119
increased or absent threshold ... 5 | 128
abnormal lens morphology 4 | 73
abnormal retina morphology 4 | 100
cardiovascular system phenotyp... 4 | 35
decreased bone mineral content 4 | 157
decreased circulating choleste... 4 | 85
increased body weight 4 | 42
increased mean corpuscular hem... 4 | 93
abnormal behavior 3 | 226
decreased body length 3 | 108
decreased circulating HDL chol... 3 | 77
decreased circulating LDL chol... 3 | 37
decreased circulating alanine ... 3 | 53
impaired glucose tolerance 3 | 52
increased blood urea nitrogen ... 3 | 44
increased mean corpuscular vol... 3 | 91
abnormal QRS complex 2 | 25
abnormal bone structure 2 | 131
abnormal embryo size 2 | 112
abnormal retinal pigmentation 2 | 61
abnormal skin morphology 2 | 23
abnormal whole-body plethysmog... 2 | 4
decreased T cell number 2 | 31
decreased circulating glucose ... 2 | 121
decreased circulating insulin ... 2 | 75
decreased circulating serum al... 2 | 79
decreased heart rate variabili... 2 | 11
decreased heart weight 2 | 44
decreased hemoglobin content 2 | 53
decreased mean corpuscular vol... 2 | 50
embryonic lethality prior to t... 2 | 187
hypoactivity 2 | 89
increased bone mineral density 2 | 52
increased circulating chloride... 2 | 43
increased circulating choleste... 2 | 53
increased circulating total pr... 2 | 20
increased fasted circulating g... 2 | 68
increased grip strength 2 | 83
increased heart rate variabili... 2 | 4
increased lean body mass 2 | 107
increased leukocyte cell numbe... 2 | 37
abnormal behavioral response t... 1 | 52
abnormal coat appearance 1 | 25
abnormal cornea morphology 1 | 24
abnormal embryo turning 1 | 15
abnormal eye morphology 1 | 38
abnormal gait 1 | 51
abnormal iris morphology 1 | 12
abnormal neural tube closure 1 | 37
abnormal respiratory quotient 1 | 9
abnormal spleen morphology 1 | 36
absent pinna reflex 1 | 21
absent vibrissae 1 | 14
cataract 1 | 26
convulsive seizures 1 | 11
corneal opacity 1 | 25
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased IgG1 level 1 | 4
decreased blood urea nitrogen ... 1 | 31
decreased caudal vertebrae num... 1 | 49
decreased circulating bilirubi... 1 | 14
decreased circulating calcium ... 1 | 33
decreased circulating chloride... 1 | 32
decreased circulating creatini... 1 | 31
decreased circulating phosphat... 1 | 15
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular hem... 1 | 19
decreased monocyte cell number 1 | 28
decreased neutrophil cell numb... 1 | 37
decreased pulmonary respirator... 1 | 4
decreased threshold for audito... 1 | 32
enlarged spleen 1 | 26
increased B cell number 1 | 23
increased blood uric acid leve... 1 | 5
increased circulating HDL chol... 1 | 63
increased circulating alanine ... 1 | 11
increased circulating amylase ... 1 | 13
increased circulating glucose ... 1 | 16
increased circulating magnesiu... 1 | 10
increased circulating triglyce... 1 | 24
increased rib number 1 | 41
increased vertical activity 1 | 18
persistence of hyaloid vascula... 1 | 22
short tibia 1 | 82
shortened ST segment 1 | 9
small thymus 1 | 11
straub tail 1 | 26
thrombocytopenia 1 | 46
tremors 1 | 34
vertebral fusion 1 | 23

Disease

osteosarcoma 126 | 7,933
ovarian cancer 119 | 8,484
psoriasis 102 | 6,685
medulloblastoma, large-cell 96 | 6,234
glioblastoma 92 | 5,572
lung cancer 69 | 4,466
lung adenocarcinoma 64 | 2,713
atypical teratoid / rhabdoid tumor 61 | 4,369
lung carcinoma 61 | 2,844
intraductal papillary-mucinous adenoma (IPMA) 60 | 2,956
malignant mesothelioma 60 | 3,162
intraductal papillary-mucinous carcinoma (IPMC) 58 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 58 | 3,289
non-small cell lung cancer 58 | 2,798
pancreatic cancer 57 | 2,300
pilocytic astrocytoma 56 | 3,086
invasive ductal carcinoma 54 | 2,950
oligodendroglioma 54 | 2,849
interstitial cystitis 53 | 2,299
pediatric high grade glioma 53 | 2,712
Cancer 48 | 2,346
Carcinoma 48 | 2,147
Breast cancer 46 | 3,094
ulcerative colitis 45 | 2,087
breast carcinoma 42 | 1,614
primitive neuroectodermal tumor 38 | 3,031
astrocytic glioma 37 | 2,241
colon cancer 37 | 1,475
posterior fossa group B ependymoma 37 | 1,530
subependymal giant cell astrocytoma 37 | 2,287
cystic fibrosis 36 | 1,665
ductal carcinoma in situ 34 | 1,745
pituitary cancer 33 | 1,972
Pick disease 32 | 1,893
diabetes mellitus 32 | 1,663
primary pancreatic ductal adenocarcinoma 30 | 1,271
adrenocortical carcinoma 29 | 1,427
ependymoma 29 | 2,514
group 3 medulloblastoma 29 | 2,254
tuberculosis 29 | 1,557
Obesity 26 | 616
astrocytoma 26 | 1,493
posterior fossa group A ependymoma 26 | 1,511
group 4 medulloblastoma 25 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 25 | 1,795
sonic hedgehog group medulloblastoma 25 | 1,482
adult high grade glioma 23 | 2,148
acute quadriplegic myopathy 22 | 1,157
medulloblastoma 22 | 1,524
spina bifida 22 | 1,064
Kidney disease 21 | 396
active Crohn's disease 21 | 918
atypical teratoid/rhabdoid tumor 21 | 1,095
cutaneous lupus erythematosus 20 | 1,056
juvenile dermatomyositis 20 | 1,189
Intellectual disability 19 | 573
Retinitis pigmentosa 19 | 153
nasopharyngeal carcinoma 18 | 1,056
fibroadenoma 17 | 557
Fundus dystrophy 16 | 77
mucosa-associated lymphoid tissue lymphoma 16 | 480
nephrosclerosis 16 | 329
Alzheimer's disease 15 | 644
Cone dystrophy 15 | 57
Down syndrome 15 | 548
Duchenne muscular dystrophy 15 | 602
Polydactyly 15 | 93
Rheumatoid Arthritis 14 | 1,160
dermatomyositis 14 | 933
gastric carcinoma 14 | 832
progressive supranuclear palsy 14 | 674
Neuropathy 13 | 210
Schizophrenia 13 | 501
Waldenstrons macroglobulinemia 13 | 765
autosomal dominant Emery-Dreifuss muscular dystrophy 13 | 499
Anemia 12 | 252
Diarrhea 12 | 155
Hypertension 12 | 287
active ulcerative colitis 12 | 477
esophageal adenocarcinoma 12 | 737
non-small cell lung carcinoma 12 | 413
Atopic dermatitis 11 | 944
Coronary artery disease 11 | 240
Hypertensive disease 11 | 193
Multiple Sclerosis 11 | 498
Prostatic Neoplasms 11 | 471
pancreatic carcinoma 11 | 567
Autistic Disorder 10 | 320
Blindness 10 | 84
Mammary Neoplasms 10 | 410
Multiple myeloma 10 | 1,327
Osteoporosis 10 | 257
chronic rhinosinusitis 10 | 512
facioscapulohumeral dystrophy 10 | 286
non primary Sjogren syndrome sicca 10 | 840
primary Sjogren syndrome 10 | 789
Atherosclerosis 9 | 275
Bardet-Biedl Syndrome 9 | 40
Polycystic Ovary Syndrome 9 | 332
aldosterone-producing adenoma 9 | 664

Tissue

Nervous System 260 | 18,561
Urinary Tract 258 | 18,444
Digestive Tract 257 | 18,473
Endocrine System 257 | 18,512
Female tissues 257 | 18,647
Liver and Pancreas 256 | 18,136
Skin and soft tissues 254 | 18,115
Blood and immune system 253 | 17,995
Cardiovascular System 252 | 17,958
Male tissues 248 | 17,969
Respiratory system 242 | 17,484

Target Family

Non-IDG 134 | 11,971
Enzyme 47 | 4,146
Transporter 36 | 473
GPCR 16 | 406
Ion Channel 15 | 341
Kinase 15 | 634

Compartment GO Term

Cell projection membrane 263 | 263
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
D(2) dopamine receptor DRD2 Tclin GPCR -3.24474 1775.2 248
Solute carrier family 13 member 1 SLC13A1 Tbio Transporter -1.70334 62.7 18
Epidermal growth factor receptor kinase substrate 8 EPS8 Tbio Enzyme -1.80380 77.2 248
Ileal sodium/bile acid cotransporter SLC10A2 Tchem Transporter -2.60727 417.5 121
Receptor-type tyrosine-protein phosphatase eta PTPRJ Tbio Enzyme -1.94494 110.6 235
Short-wave-sensitive opsin 1 OPN1SW Tbio GPCR -1.90084 81.3 15
Bardet-Biedl syndrome 7 protein BBS7 Tbio Non-IDG -1.02867 11.1 125
Protein KIBRA WWC1 Tbio Non-IDG -1.88892 84.4 96
Sodium-dependent phosphate transporter 2 SLC20A2 Tbio Transporter -2.18737 165.3 97
C2 domain-containing protein 5 C2CD5 Tbio Non-IDG 0.27 0.49 34