Development Level

Tbio 1,080 | 11,445
Tchem 187 | 1,598
Tdark 158 | 6,588
Tclin 116 | 613

Collection

Kinase: IDG Consortium (Target... 11 | 125
Kinase: IDG Consortium (Comple... 10 | 37
Ion Channel: IDG Consortium (T... 9 | 99
GPCR: IDG Consortium (Targets) 8 | 126
GPCR: IDG Consortium (Complete... 3 | 25

IMPC Phenotype

preweaning lethality, complete... 97 | 979
preweaning lethality, incomple... 64 | 499
abnormal behavior 45 | 298
embryonic lethality prior to t... 28 | 278
abnormal embryo size 25 | 220
increased lean body mass 24 | 172
decreased total body fat amoun... 23 | 207
hyperactivity 23 | 148
decreased body weight 22 | 161
abnormal bone structure 20 | 187
increased total body fat amoun... 20 | 134
increased startle reflex 19 | 112
decreased grip strength 18 | 116
decreased vertical activity 18 | 208
increased circulating sodium l... 18 | 71
embryonic growth retardation 16 | 106
embryonic lethality prior to o... 16 | 239
hypoactivity 16 | 132
decreased circulating choleste... 15 | 93
decreased circulating glucose ... 15 | 126
decreased lean body mass 15 | 135
edema 15 | 59
increased circulating alkaline... 15 | 122
increased fasted circulating g... 15 | 76
abnormal retina morphology 14 | 71
increased bone mineral content 14 | 108
increased circulating chloride... 14 | 41
decreased bone mineral content 13 | 151
impaired glucose tolerance 13 | 75
increased mean corpuscular vol... 13 | 92
increased or absent threshold ... 13 | 101
male infertility 13 | 123
decreased circulating serum al... 12 | 82
increased heart weight 12 | 62
abnormal eye morphology 11 | 68
cataract 11 | 92
decreased circulating HDL chol... 11 | 68
decreased circulating alkaline... 11 | 46
decreased startle reflex 11 | 75
increased mean corpuscular hem... 11 | 96
prenatal lethality prior to he... 11 | 87
abnormal behavioral response t... 10 | 66
decreased circulating total pr... 10 | 49
decreased circulating triglyce... 10 | 79
decreased fasted circulating g... 10 | 65
decreased prepulse inhibition 10 | 82
enlarged heart 10 | 210
limb grasping 10 | 41
short tibia 10 | 97
abnormal heart morphology 9 | 162
decreased circulating LDL chol... 9 | 38
improved glucose tolerance 9 | 79
persistence of hyaloid vascula... 9 | 33
abnormal gait 8 | 69
decreased bone mineral density 8 | 126
decreased circulating alanine ... 8 | 47
decreased circulating insulin ... 8 | 76
decreased mean corpuscular vol... 8 | 79
increased bone mineral density 8 | 72
prolonged ST segment 8 | 36
tremors 8 | 39
abnormal embryo turning 7 | 31
abnormal pericardium morpholog... 7 | 26
decreased leukocyte cell numbe... 7 | 73
decreased lymphocyte cell numb... 7 | 83
decreased neutrophil cell numb... 7 | 42
increased blood urea nitrogen ... 7 | 48
increased body weight 7 | 25
increased circulating triglyce... 7 | 42
small testis 7 | 58
abnormal bone mineralization 6 | 38
abnormal lens morphology 6 | 81
abnormal locomotor behavior 6 | 24
abnormal neural tube closure 6 | 46
abnormal seminal vesicle morph... 6 | 114
abnormal sleep behavior 6 | 70
cardiovascular system phenotyp... 6 | 36
decreased circulating aspartat... 6 | 34
decreased hemoglobin content 6 | 68
increased circulating choleste... 6 | 66
increased lymphocyte cell numb... 6 | 32
prolonged QT interval 6 | 38
small superior vagus ganglion 6 | 74
abnormal coat-hair pigmentatio... 5 | 64
abnormal testis morphology 5 | 43
decreased body length 5 | 101
decreased caudal vertebrae num... 5 | 53
decreased circulating amylase ... 5 | 28
decreased circulating potassiu... 5 | 20
decreased erythrocyte cell num... 5 | 62
hemorrhage 5 | 23
hydrometra 5 | 53
increased circulating iron lev... 5 | 30
increased grip strength 5 | 41
increased vertical activity 5 | 24
polycystic kidney 5 | 15
abnormal placenta size 4 | 20
decreased circulating fructosa... 4 | 30
increased circulating free fat... 4 | 20
pallor 4 | 34

Disease

Carcinoma 1,142 | 11,493
ovarian cancer 706 | 8,520
osteosarcoma 704 | 7,950
medulloblastoma, large-cell 680 | 6,241
glioblastoma 662 | 5,792
ependymoma 618 | 4,679
psoriasis 598 | 6,694
atypical teratoid / rhabdoid tumor 594 | 5,112
adult high grade glioma 476 | 3,801
lung cancer 435 | 4,740
group 3 medulloblastoma 429 | 4,104
Astrocytoma, Pilocytic 411 | 3,081
Kidney cancer 387 | 2,613
oligodendroglioma 377 | 2,850
Breast cancer 372 | 3,578
primitive neuroectodermal tumor 343 | 3,035
lung carcinoma 342 | 2,843
astrocytic glioma 335 | 2,597
malignant mesothelioma 323 | 3,232
Cancer 312 | 2,499
intraductal papillary-mucinous adenoma (IPMA) 300 | 2,955
invasive ductal carcinoma 290 | 2,951
intraductal papillary-mucinous neoplasm (IPMN) 285 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 284 | 2,989
lung adenocarcinoma 278 | 2,716
non-small cell lung cancer 272 | 2,890
subependymal giant cell astrocytoma 264 | 2,287
Schizophrenia 261 | 1,160
Pick disease 239 | 1,894
pancreatic cancer 234 | 2,398
interstitial cystitis 225 | 2,312
pituitary cancer 221 | 1,972
Autosomal recessive predisposition 204 | 1,442
Intellectual disability 200 | 1,016
group 4 medulloblastoma 193 | 1,855
ulcerative colitis 189 | 1,819
tuberculosis 187 | 2,010
diabetes mellitus 178 | 1,728
Alzheimer's disease 176 | 658
Bipolar Disorder 175 | 666
colon cancer 175 | 1,478
cystic fibrosis 172 | 1,696
ductal carcinoma in situ 169 | 1,745
breast carcinoma 165 | 1,638
Epilepsy 159 | 792
Obesity 153 | 678
pancreatic ductal adenocarcinoma liver metastasis 138 | 1,962
Depressive disorder 135 | 409
nasopharyngeal carcinoma 131 | 1,058
Liver cancer 127 | 604
Dull intelligence 125 | 645
Low intelligence 125 | 645
Mental Retardation 125 | 645
Mental deficiency 125 | 645
Poor school performance 125 | 645
adrenocortical carcinoma 125 | 1,428
astrocytoma 125 | 1,146
Seizures 123 | 596
Parkinson's disease 118 | 392
pediatric high grade glioma 116 | 1,064
Mental Depression 111 | 333
Melanoma 108 | 711
primary pancreatic ductal adenocarcinoma 108 | 1,109
chronic rhinosinusitis 105 | 512
cutaneous lupus erythematosus 104 | 1,057
acute quadriplegic myopathy 103 | 1,158
Kidney disease 101 | 430
Neurodegenerative disease 100 | 414
juvenile dermatomyositis 100 | 1,187
spina bifida 99 | 1,074
Rheumatoid arthritis 98 | 1,191
Autistic Disorder 96 | 364
Alcoholic Intoxication, Chronic 94 | 289
Cognitive delay 94 | 608
Global developmental delay 94 | 608
Mental and motor retardation 94 | 608
Hypertension 90 | 396
Major Depressive Disorder 89 | 301
Skin cancer 88 | 469
Amyotrophic lateral sclerosis 87 | 451
Toxic encephalopathy 84 | 141
Multiple myeloma 83 | 1,332
gastric carcinoma 83 | 807
Down syndrome 79 | 499
Nystagmus 79 | 317
Liver Cirrhosis, Experimental 78 | 769
Muscle hypotonia 78 | 571
dermatomyositis 78 | 966
Retinitis Pigmentosa 77 | 226
progressive supranuclear palsy 77 | 676
Atopic dermatitis 76 | 952
Neuropathy 75 | 261
Unipolar Depression 75 | 250
aldosterone-producing adenoma 74 | 665
non primary Sjogren syndrome sicca 74 | 891
Hypertensive disease 72 | 292
Asthma 71 | 385
Cerebrovascular disease 71 | 238
active Crohn's disease 70 | 922
Cataract 68 | 297

Tissue

Endocrine System 1,502 | 18,159
Digestive Tract 1,453 | 17,369
Female tissues 1,451 | 17,400
Nervous System 1,447 | 16,725
Skin and soft tissues 1,442 | 17,230
Male tissues 1,436 | 17,142
Liver and Pancreas 1,407 | 16,750
Blood and immune system 1,401 | 16,909
Urinary Tract 1,397 | 16,678
Respiratory system 1,380 | 16,393
Cardiovascular System 1,259 | 15,192

Target Family

Non-IDG 993 | 12,091
Enzyme 231 | 4,145
Kinase 101 | 634
Ion Channel 73 | 344
GPCR 63 | 408
Transporter 52 | 473
Transcription Factor 20 | 1,400
Epigenetic 7 | 242
Nuclear Receptor 1 | 48

Compartment GO Term

Cell projection 1,541 | 1,541
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras-related protein Rab-22A RAB22A Tbio Enzyme -1.40824 19.7 123
Thrombopoietin THPO Tbio Non-IDG -3.23551 1632.3 440
Beta-1,4-galactosyltransferase 1 B4GALT1 Tbio Enzyme -2.34454 211.1 130
Atlastin-1 ATL1 Tbio Non-IDG -2.07795 119.7 164
Adhesion G-protein coupled receptor G1 ADGRG1 Tbio GPCR -1.94601 100.6 182
Protocadherin-15 PCDH15 Tbio Non-IDG -1.83877 74.3 42
Serine/threonine-protein kinase MRCK beta CDC42BPB Tbio Kinase -0.59618 3.72 111
Hedgehog-interacting protein HHIP Tbio Non-IDG -1.83526 65.4 193
Unconventional myosin-XV MYO15A Tbio Non-IDG -1.64094 42.8 15
Sorting nexin-14 SNX14 Tbio Non-IDG -0.86091 6.82 56