Development Level

Tbio 3,344 | 11,651
Tdark 986 | 6,593
Tchem 628 | 1,388
Tclin 423 | 612

Collection

GPCR: IDG Consortium (Targets) 119 | 126
Ion Channel: IDG Consortium (T... 85 | 99
GPCR: IDG Consortium (Complete... 24 | 25
Kinase: IDG Consortium (Target... 21 | 125
Kinase: IDG Consortium (Comple... 7 | 37

IMPC Phenotype

preweaning lethality, complete... 233 | 979
preweaning lethality, incomple... 159 | 499
abnormal behavior 101 | 298
decreased vertical activity 79 | 208
embryonic lethality prior to t... 77 | 278
enlarged heart 69 | 210
decreased total body fat amoun... 67 | 207
abnormal bone structure 60 | 187
abnormal embryo size 58 | 220
embryonic lethality prior to o... 55 | 239
decreased body weight 53 | 161
hyperactivity 53 | 148
increased lean body mass 53 | 172
abnormal heart morphology 49 | 162
decreased bone mineral content 49 | 151
increased total body fat amoun... 49 | 134
abnormal seminal vesicle morph... 42 | 114
increased circulating alkaline... 40 | 122
decreased lean body mass 38 | 135
increased startle reflex 38 | 112
decreased bone mineral density 37 | 126
hypoactivity 35 | 132
increased bone mineral content 35 | 108
decreased circulating glucose ... 34 | 126
increased or absent threshold ... 34 | 101
decreased grip strength 31 | 116
embryonic growth retardation 31 | 106
short tibia 31 | 97
decreased lymphocyte cell numb... 30 | 83
improved glucose tolerance 30 | 79
decreased prepulse inhibition 29 | 82
abnormal retina morphology 28 | 71
decreased circulating choleste... 28 | 93
abnormal gait 27 | 69
decreased mean corpuscular vol... 27 | 79
impaired glucose tolerance 27 | 75
increased mean corpuscular vol... 27 | 92
small superior vagus ganglion 27 | 74
decreased body length 26 | 101
decreased fasted circulating g... 26 | 65
prenatal lethality prior to he... 26 | 87
decreased circulating insulin ... 25 | 76
decreased startle reflex 25 | 75
increased heart weight 24 | 62
limb grasping 24 | 41
abnormal sleep behavior 23 | 70
cataract 23 | 92
increased monocyte cell number 23 | 63
decreased leukocyte cell numbe... 22 | 73
increased circulating sodium l... 22 | 71
increased leukocyte cell numbe... 22 | 47
increased mean corpuscular hem... 22 | 96
abnormal kidney morphology 21 | 65
decreased circulating HDL chol... 21 | 68
decreased circulating triglyce... 21 | 79
edema 21 | 59
increased circulating chloride... 21 | 41
increased fasted circulating g... 21 | 76
abnormal eye morphology 20 | 68
decreased hemoglobin content 20 | 68
tremors 20 | 39
abnormal lens morphology 19 | 81
decreased circulating creatini... 19 | 39
increased circulating HDL chol... 19 | 80
increased neutrophil cell numb... 19 | 46
male infertility 19 | 123
decreased circulating serum al... 18 | 82
increased blood urea nitrogen ... 18 | 48
increased circulating choleste... 18 | 66
increased circulating triglyce... 18 | 42
thrombocytopenia 18 | 56
abnormal skin morphology 17 | 50
hydrometra 17 | 53
increased bone mineral density 17 | 72
increased hematocrit 17 | 46
abnormal epididymis morphology 16 | 42
abnormal spleen morphology 16 | 55
cardiovascular system phenotyp... 16 | 36
decreased erythrocyte cell num... 16 | 62
decreased mean corpuscular hem... 16 | 50
increased hemoglobin content 16 | 45
enlarged spleen 15 | 41
increased circulating calcium ... 15 | 34
prolonged QT interval 15 | 38
small testis 15 | 58
abnormal coat appearance 14 | 31
abnormal coat-hair pigmentatio... 14 | 64
abnormal neural tube closure 14 | 46
abnormal testis morphology 14 | 43
decreased neutrophil cell numb... 14 | 42
increased circulating creatini... 14 | 38
pallor 14 | 34
prolonged ST segment 14 | 36
abnormal behavioral response t... 13 | 66
decreased blood urea nitrogen ... 13 | 51
decreased circulating alkaline... 13 | 46
decreased circulating amylase ... 13 | 28
enlarged epididymis 13 | 31
increased mean platelet volume 13 | 45
persistence of hyaloid vascula... 13 | 33

Disease

Carcinoma 3,785 | 11,493
ovarian cancer 2,293 | 8,520
osteosarcoma 2,226 | 7,950
psoriasis 2,111 | 6,694
glioblastoma 1,909 | 5,792
medulloblastoma, large-cell 1,908 | 6,241
atypical teratoid / rhabdoid tumor 1,643 | 5,112
ependymoma 1,534 | 4,679
lung cancer 1,525 | 4,740
adult high grade glioma 1,341 | 3,801
Astrocytoma, Pilocytic 1,217 | 3,081
lung carcinoma 1,215 | 2,843
group 3 medulloblastoma 1,145 | 4,104
Breast cancer 1,114 | 3,578
Cancer 1,111 | 2,499
non-small cell lung cancer 1,030 | 2,890
Kidney cancer 1,020 | 2,613
malignant mesothelioma 1,015 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 1,012 | 3,291
invasive ductal carcinoma 1,009 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 991 | 2,955
lung adenocarcinoma 990 | 2,716
oligodendroglioma 964 | 2,850
intraductal papillary-mucinous carcinoma (IPMC) 950 | 2,989
interstitial cystitis 940 | 2,312
primitive neuroectodermal tumor 922 | 3,035
pancreatic cancer 877 | 2,398
subependymal giant cell astrocytoma 835 | 2,287
astrocytic glioma 823 | 2,597
tuberculosis 722 | 2,010
ulcerative colitis 695 | 1,819
diabetes mellitus 689 | 1,728
pituitary cancer 686 | 1,972
ductal carcinoma in situ 619 | 1,745
cystic fibrosis 615 | 1,696
group 4 medulloblastoma 581 | 1,855
Pick disease 577 | 1,894
Schizophrenia 567 | 1,160
breast carcinoma 547 | 1,638
Autosomal recessive predisposition 530 | 1,442
pancreatic ductal adenocarcinoma liver metastasis 530 | 1,962
colon cancer 508 | 1,478
cutaneous lupus erythematosus 461 | 1,057
Rheumatoid arthritis 443 | 1,191
adrenocortical carcinoma 441 | 1,428
primary pancreatic ductal adenocarcinoma 405 | 1,109
astrocytoma 385 | 1,146
juvenile dermatomyositis 353 | 1,187
active Crohn's disease 336 | 922
pediatric high grade glioma 334 | 1,064
Melanoma 332 | 711
spina bifida 330 | 1,074
Intellectual disability 325 | 1,016
Bipolar Disorder 324 | 666
acute quadriplegic myopathy 324 | 1,158
nasopharyngeal carcinoma 319 | 1,058
Epilepsy 315 | 792
Liver Cirrhosis, Experimental 311 | 769
dermatomyositis 311 | 966
Atopic dermatitis 307 | 952
Obesity 306 | 678
active ulcerative colitis 306 | 764
gastric carcinoma 303 | 807
Alzheimer's disease 302 | 658
esophageal adenocarcinoma 298 | 737
Multiple myeloma 296 | 1,332
primary Sjogren syndrome 286 | 735
Multiple Sclerosis 285 | 540
Liver cancer 281 | 604
Kidney disease 263 | 430
Duchenne muscular dystrophy 253 | 601
Hypertension 252 | 396
Skin cancer 246 | 469
non primary Sjogren syndrome sicca 246 | 891
mucosa-associated lymphoid tissue lymphoma 236 | 484
Down syndrome 226 | 499
aldosterone-producing adenoma 219 | 665
Seizures 213 | 596
Asthma 212 | 385
Depressive disorder 212 | 409
Arthritis 211 | 290
Dull intelligence 205 | 645
Hypersensitivity reaction type II disease 205 | 253
Low intelligence 205 | 645
Mental Retardation 205 | 645
Mental deficiency 205 | 645
Poor school performance 205 | 645
fibroadenoma 202 | 559
medulloblastoma 200 | 720
acute myeloid leukemia 199 | 783
Autistic Disorder 198 | 364
autosomal dominant Emery-Dreifuss muscular dystrophy 196 | 510
Anemia 191 | 365
Parkinson's disease 191 | 392
Prostatic Neoplasms 190 | 495
Breast Neoplasms 183 | 445
Waldenstrons macroglobulinemia 183 | 765
progressive supranuclear palsy 183 | 676
Alcoholic Intoxication, Chronic 181 | 289
Endometriosis 180 | 540

Tissue

Endocrine System 4,841 | 18,159
Digestive Tract 4,652 | 17,369
Female tissues 4,651 | 17,400
Skin and soft tissues 4,597 | 17,230
Male tissues 4,554 | 17,142
Blood and immune system 4,513 | 16,909
Nervous System 4,496 | 16,725
Urinary Tract 4,479 | 16,678
Liver and Pancreas 4,473 | 16,750
Respiratory system 4,333 | 16,393
Cardiovascular System 3,961 | 15,192

Target Family

Non-IDG 2,799 | 12,091
Enzyme 821 | 4,145
GPCR 391 | 408
oGPCR 380 | 421
Transporter 361 | 473
Ion Channel 320 | 344
Kinase 239 | 634
Transcription Factor 43 | 1,400
Epigenetic 18 | 242
Nuclear Receptor 5 | 48
TF/Epigenetic 4 | 38

Compartment GO Term

Cell periphery 5,381 | 5,381
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paralemmin-3 PALM3 Tbio Non-IDG -0.66901 5.71 76
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.30856 210.6 116
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.33715 23.1 275
Ras-related protein Rab-22A RAB22A Tbio Enzyme -1.40824 19.7 123
Olfactory receptor 5H15 OR5H15 Tdark oGPCR 0.00000 35
43 kDa receptor-associated protein of the synapse RAPSN Tbio Non-IDG -2.09902 132.1 134
Olfactory receptor 7D2 OR7D2 Tdark oGPCR 0.00000 2
Integrin alpha-11 ITGA11 Tbio Non-IDG -1.13736 14.3 76
Annexin A13 ANXA13 Tbio Non-IDG -1.19458 15.6 162
Tyrosine-protein phosphatase non-receptor type 5 PTPN5 Tchem Enzyme -1.85420 70.8 225