Development Level

Tbio 43 | 10,625
Tchem 12 | 1,890
Tdark 6 | 7,003
Tclin 3 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 6 | 633
preweaning lethality, incomple... 3 | 260
abnormal head morphology 2 | 10
decreased circulating calcium ... 2 | 33
decreased grip strength 2 | 123
decreased monocyte cell number 2 | 28
abnormal behavior 1 | 226
abnormal coat appearance 1 | 25
abnormal cranium morphology 1 | 32
abnormal placenta size 1 | 10
abnormal skin coloration 1 | 18
absent teeth 1 | 4
decreased NK T cell number 1 | 28
decreased circulating potassiu... 1 | 17
decreased leukocyte cell numbe... 1 | 54
edema 1 | 11
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
female infertility 1 | 34
hemorrhage 1 | 12
hypoactivity 1 | 89
immune system phenotype 1 | 17
improved glucose tolerance 1 | 56
increased CD4-positive NK T ce... 1 | 3
increased NK T cell number 1 | 11
increased circulating alkaline... 1 | 119
increased mean corpuscular hem... 1 | 93
increased memory-marker CD4-po... 1 | 3
increased total body fat amoun... 1 | 57
prenatal lethality prior to he... 1 | 64
tremors 1 | 34

Disease

ovarian cancer 38 | 8,492
osteosarcoma 36 | 7,933
glioblastoma 34 | 5,572
medulloblastoma, large-cell 32 | 6,234
psoriasis 30 | 6,685
atypical teratoid / rhabdoid tumor 23 | 4,369
pediatric high grade glioma 21 | 2,712
Cancer 20 | 2,346
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,289
primitive neuroectodermal tumor 20 | 3,031
lung cancer 19 | 4,473
pancreatic cancer 18 | 2,300
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,988
invasive ductal carcinoma 16 | 2,950
malignant mesothelioma 14 | 3,163
pilocytic astrocytoma 14 | 3,086
Breast cancer 13 | 3,099
adrenocortical carcinoma 13 | 1,427
lung adenocarcinoma 13 | 2,714
non-small cell lung cancer 13 | 2,798
colon cancer 12 | 1,475
oligodendroglioma 12 | 2,849
Carcinoma 11 | 2,147
subependymal giant cell astrocytoma 11 | 2,287
ulcerative colitis 11 | 2,087
Multiple myeloma 10 | 1,328
astrocytic glioma 10 | 2,241
group 3 medulloblastoma 10 | 2,254
primary pancreatic ductal adenocarcinoma 10 | 1,271
ductal carcinoma in situ 9 | 1,745
ependymoma 9 | 2,514
posterior fossa group A ependymoma 9 | 1,511
sonic hedgehog group medulloblastoma 9 | 1,482
Atopic dermatitis 8 | 944
Endometriosis 8 | 535
IGA Glomerulonephritis 8 | 454
Pick disease 8 | 1,893
breast carcinoma 8 | 1,614
interstitial cystitis 8 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,956
atypical teratoid/rhabdoid tumor 7 | 1,095
dermatomyositis 7 | 967
diabetes mellitus 7 | 1,663
group 4 medulloblastoma 7 | 1,875
juvenile dermatomyositis 7 | 1,189
lung carcinoma 7 | 2,844
nasopharyngeal carcinoma 7 | 1,056
non primary Sjogren syndrome sicca 7 | 840
progressive supranuclear palsy 7 | 674
tuberculosis 7 | 1,563
acute quadriplegic myopathy 6 | 1,157
adult high grade glioma 6 | 2,148
Hypercalcemia 5 | 37
Hyperparathyroidism 5 | 43
Hypoparathyroidism 5 | 29
Microcephaly 5 | 149
Waldenstrons macroglobulinemia 5 | 765
active Crohn's disease 5 | 918
astrocytoma 5 | 1,493
esophageal adenocarcinoma 5 | 737
medulloblastoma 5 | 1,524
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
posterior fossa group B ependymoma 5 | 1,530
Arthritis 4 | 248
Down syndrome 4 | 548
Hypertension 4 | 293
Hypophosphatemia 4 | 31
Kidney disease 4 | 397
Multiple Sclerosis 4 | 498
Osteoporosis 4 | 259
Parathyroid Adenoma 4 | 11
Polycystic Ovary Syndrome 4 | 335
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 499
chronic rhinosinusitis 4 | 512
cutaneous lupus erythematosus 4 | 1,056
cystic fibrosis 4 | 1,670
non-small cell lung carcinoma 4 | 413
Adenoma 3 | 165
Amyotrophic Lateral Sclerosis 3 | 432
Asthma 3 | 349
Crohn's disease 3 | 304
Duchenne muscular dystrophy 3 | 602
Epilepsy 3 | 346
Gaucher disease type 1 3 | 171
Hyperphosphatemia 3 | 32
Intellectual disability 3 | 573
Renal Cell Carcinoma 3 | 199
Rheumatoid Arthritis 3 | 1,171
Schizophrenia 3 | 503
Stomach Neoplasms 3 | 282
cystic fibrosis and chronic rhinosinusitis 3 | 213
fibroadenoma 3 | 557
gastric cancer 3 | 436
gastric carcinoma 3 | 832
hereditary spastic paraplegia 3 | 313
pancreatic carcinoma 3 | 567
pituitary cancer 3 | 1,972
primary Sjogren syndrome 3 | 789
spina bifida 3 | 1,064
tuberculosis and treatment for 6 months 3 | 686

Tissue

Endocrine System 64 | 18,512
Female tissues 64 | 18,647
Nervous System 64 | 18,561
Digestive Tract 63 | 18,473
Liver and Pancreas 63 | 18,136
Urinary Tract 63 | 18,444
Male tissues 62 | 17,969
Skin and soft tissues 62 | 18,115
Blood and immune system 61 | 17,995
Cardiovascular System 61 | 17,958
Respiratory system 60 | 17,484

Target Family

Non-IDG 38 | 11,969
Enzyme 13 | 4,146
Kinase 8 | 634
GPCR 3 | 408
Nuclear Receptor 1 | 48
oGPCR 1 | 421

Compartment GO Term

Cell division site part 64 | 64
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Gamma-tubulin complex component 2 TUBGCP2 Tdark Non-IDG -0.77055 4.80 96
LIM domain and actin-binding protein 1 LIMA1 Tbio Non-IDG -1.19919 22.9 167
Serine/threonine-protein kinase PLK1 PLK1 Tchem Kinase -3.06059 1176.3 707
Proline-serine-threonine phosphatase-interacting protein 1 PSTPIP1 Tbio Enzyme -1.87114 77.0 104
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.31835 22.7 168
Fibronectin type III and SPRY domain-containing protein 1 FSD1 Tbio Non-IDG -1.37592 22.8 126
Nuclear distribution protein nudE homolog 1 NDE1 Tbio Non-IDG -1.97644 90.5 165
Pleckstrin homology domain-containing family G member 6 PLEKHG6 Tbio Non-IDG -0.52628 4.38 92
ADP-ribosylation factor 6 ARF6 Tchem Enzyme -2.46255 333.2 252
Ras-related protein Rab-11A RAB11A Tbio Enzyme -2.62399 398.9 288