Development Level

Tbio 50 | 11,651
Tchem 10 | 1,388
Tdark 7 | 6,593
Tclin 4 | 612

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 11 | 979
preweaning lethality, incomple... 5 | 499
abnormal behavior 2 | 298
decreased circulating calcium ... 2 | 36
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
enlarged heart 2 | 210
abnormal coat appearance 1 | 31
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal pancreas morphology 1 | 13
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal skin coloration 1 | 25
absent startle reflex 1 | 24
absent teeth 1 | 3
cardiovascular system phenotyp... 1 | 36
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating unsatura... 1 | 2
decreased eosinophil cell numb... 1 | 24
decreased grip strength 1 | 116
decreased large unstained cell... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged uterus 1 | 11
female infertility 1 | 60
hemorrhage 1 | 23
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased exploration in new e... 1 | 8
increased heart rate variabili... 1 | 7
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small superior vagus ganglion 1 | 74
tremors 1 | 39

Disease

Carcinoma 50 | 11,493
ovarian cancer 42 | 8,520
osteosarcoma 40 | 7,950
glioblastoma 37 | 5,792
medulloblastoma, large-cell 37 | 6,241
psoriasis 34 | 6,694
atypical teratoid / rhabdoid tumor 31 | 5,112
primitive neuroectodermal tumor 23 | 3,035
Cancer 22 | 2,499
ependymoma 21 | 4,679
lung cancer 21 | 4,740
adult high grade glioma 20 | 3,801
group 3 medulloblastoma 20 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,291
pancreatic cancer 20 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
invasive ductal carcinoma 17 | 2,951
Astrocytoma, Pilocytic 16 | 3,081
Breast cancer 16 | 3,578
malignant mesothelioma 16 | 3,232
lung adenocarcinoma 15 | 2,716
non-small cell lung cancer 15 | 2,890
Kidney cancer 14 | 2,613
adrenocortical carcinoma 13 | 1,428
colon cancer 13 | 1,478
oligodendroglioma 13 | 2,850
subependymal giant cell astrocytoma 12 | 2,287
ulcerative colitis 12 | 1,819
Multiple myeloma 10 | 1,332
astrocytic glioma 10 | 2,597
breast carcinoma 10 | 1,638
ductal carcinoma in situ 10 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
lung carcinoma 10 | 2,843
pediatric high grade glioma 10 | 1,064
Endometriosis 9 | 540
Schizophrenia 9 | 1,160
Atopic dermatitis 8 | 952
Pick disease 8 | 1,894
dermatomyositis 8 | 966
group 4 medulloblastoma 8 | 1,855
interstitial cystitis 8 | 2,312
juvenile dermatomyositis 8 | 1,187
primary pancreatic ductal adenocarcinoma 8 | 1,109
Epilepsy 7 | 792
diabetes mellitus 7 | 1,728
non primary Sjogren syndrome sicca 7 | 891
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
progressive supranuclear palsy 7 | 676
tuberculosis 7 | 2,010
Autosomal recessive predisposition 6 | 1,442
Seizures 6 | 596
Short stature 6 | 531
acute quadriplegic myopathy 6 | 1,158
astrocytoma 6 | 1,146
esophageal adenocarcinoma 6 | 737
medulloblastoma 6 | 720
nasopharyngeal carcinoma 6 | 1,058
Hypercalcemia 5 | 59
Hyperparathyroidism 5 | 48
Hypoparathyroidism 5 | 41
Hypophosphatemia 5 | 40
Kidney disease 5 | 430
Liver cancer 5 | 604
Microcephaly 5 | 166
Multiple Sclerosis 5 | 540
Osteoporosis 5 | 363
Waldenstrons macroglobulinemia 5 | 765
active Crohn's disease 5 | 922
chronic rhinosinusitis 5 | 512
Arthritis 4 | 290
Down syndrome 4 | 499
Hypertensive disease 4 | 292
Intellectual disability 4 | 1,016
Liver Cirrhosis, Experimental 4 | 769
Melanoma 4 | 711
Neoplasm Invasiveness 4 | 161
Parathyroid Adenoma 4 | 19
Polycystic ovary syndrome 4 | 360
Prenatal onset 4 | 139
Rheumatoid arthritis 4 | 1,191
Skin cancer 4 | 469
Sloping forehead 4 | 46
Stomach Neoplasms 4 | 300
acute myeloid leukemia 4 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
cutaneous lupus erythematosus 4 | 1,057
cystic fibrosis 4 | 1,696
gastric cancer 4 | 459
posterior fossa group A ependymoma 4 | 468
tuberculosis and treatment for 6 months 4 | 409
Depressive disorder 3 | 409
Duchenne muscular dystrophy 3 | 601
Mental Depression 3 | 333
fibroadenoma 3 | 559
gastric carcinoma 3 | 807
nephrosclerosis 3 | 333
pancreatic carcinoma 3 | 562
pituitary cancer 3 | 1,972
spina bifida 3 | 1,074

Tissue

Endocrine System 71 | 18,159
Digestive Tract 70 | 17,369
Skin and soft tissues 68 | 17,230
Urinary Tract 68 | 16,678
Blood and immune system 67 | 16,909
Female tissues 67 | 17,400
Male tissues 67 | 17,142
Nervous System 67 | 16,725
Liver and Pancreas 66 | 16,750
Respiratory system 65 | 16,393
Cardiovascular System 63 | 15,192

Target Family

Non-IDG 43 | 12,091
Enzyme 14 | 4,145
Kinase 8 | 634
GPCR 3 | 408
Ion Channel 1 | 344
Nuclear Receptor 1 | 48
oGPCR 1 | 421

Compartment GO Term

Cell division site 71 | 71
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.33715 23.1 275
Myosin light chain kinase, smooth muscle MYLK Tchem Kinase -2.81312 694.0 219
Fibronectin type III and SPRY domain-containing protein 1 FSD1 Tbio Non-IDG -1.38197 23.9 160
Pleckstrin homology domain-containing family G member 6 PLEKHG6 Tbio Non-IDG -0.56736 4.94 109
Gamma-tubulin complex component 2 TUBGCP2 Tdark Non-IDG -0.75255 4.80 109
Rab11 family-interacting protein 4 RAB11FIP4 Tbio Non-IDG -0.68187 5.48 43
Ras-related protein Rab-11A RAB11A Tbio Enzyme -2.65458 432.1 352
Protein phosphatase Slingshot homolog 1 SSH1 Tbio Enzyme -1.45823 27.6 148
Dual specificity protein phosphatase CDC14A CDC14A Tbio Enzyme -2.31524 216.3 245
Gamma-tubulin complex component 5 TUBGCP5 Tbio Non-IDG -0.81376 5.88 99