Development Level

Tbio 32 | 11,445
Tchem 4 | 1,598

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
abnormal retina morphology 2 | 71
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
abnormal lens morphology 1 | 81
abnormal optic disc morphology 1 | 10
abnormal spleen morphology 1 | 55
cataract 1 | 92
decreased caudal vertebrae num... 1 | 53
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased mean corpuscular hem... 1 | 36
increased mean platelet volume 1 | 45

Disease

Carcinoma 28 | 11,493
ovarian cancer 23 | 8,520
medulloblastoma, large-cell 17 | 6,241
osteosarcoma 17 | 7,950
psoriasis 14 | 6,694
glioblastoma 13 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
oligodendroglioma 13 | 2,850
Kidney cancer 12 | 2,613
atypical teratoid / rhabdoid tumor 12 | 5,112
ependymoma 12 | 4,679
group 3 medulloblastoma 12 | 4,104
invasive ductal carcinoma 12 | 2,951
Pick disease 11 | 1,894
adult high grade glioma 11 | 3,801
primitive neuroectodermal tumor 11 | 3,035
Breast cancer 10 | 3,578
astrocytic glioma 10 | 2,597
pancreatic cancer 10 | 2,398
Astrocytoma, Pilocytic 9 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
lung carcinoma 9 | 2,843
malignant mesothelioma 9 | 3,232
subependymal giant cell astrocytoma 9 | 2,287
breast carcinoma 8 | 1,638
ductal carcinoma in situ 8 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
group 4 medulloblastoma 7 | 1,855
interstitial cystitis 7 | 2,312
lung cancer 7 | 4,740
primary pancreatic ductal adenocarcinoma 7 | 1,109
Cancer 6 | 2,499
non-small cell lung cancer 6 | 2,890
Duchenne muscular dystrophy 5 | 601
Liver cancer 5 | 604
juvenile dermatomyositis 5 | 1,187
lung adenocarcinoma 5 | 2,716
pituitary cancer 5 | 1,972
Amyotrophic lateral sclerosis 4 | 451
Rheumatoid arthritis 4 | 1,191
Waldenstrons macroglobulinemia 4 | 765
acute quadriplegic myopathy 4 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
diabetes mellitus 4 | 1,728
esophageal adenocarcinoma 4 | 737
gastric carcinoma 4 | 807
Acute cystitis 3 | 35
Atopic dermatitis 3 | 952
Autosomal recessive predisposition 3 | 1,442
Depressive disorder 3 | 409
Liver Cirrhosis, Experimental 3 | 769
Muscle Spasticity 3 | 195
Neurodegenerative Disorders 3 | 79
Schizophrenia 3 | 1,160
active Crohn's disease 3 | 922
cystic fibrosis 3 | 1,696
dermatomyositis 3 | 966
progressive supranuclear palsy 3 | 676
tuberculosis 3 | 2,010
ulcerative colitis 3 | 1,819
Anxiety 2 | 136
Anxiety disease 2 | 113
Becker muscular dystrophy 2 | 191
Diarrhea 2 | 253
Down syndrome 2 | 499
Fatigue 2 | 182
Frontotemporal dementia 2 | 51
Gaucher disease type 1 2 | 180
Generalized muscle weakness 2 | 57
Hypoplasia of corpus callosum 2 | 90
Lymphoid leukemia 2 | 160
Melanoma 2 | 711
Mental Depression 2 | 333
Mood Disorders 2 | 184
Mood swings 2 | 77
Neoplasm Invasiveness 2 | 161
Nerve Degeneration 2 | 121
Neurodegenerative disease 2 | 414
Neurogenic Muscular Atrophy 2 | 139
Neurogenic muscle atrophy, especially in the lower limbs 2 | 139
Neuropathy 2 | 261
Osteoporosis 2 | 363
Parkinson's disease 2 | 392
Pneumonia 2 | 174
Prostatic Neoplasms 2 | 495
Respiratory Failure 2 | 104
Skeletal muscle atrophy 2 | 139
Weight decreased 2 | 103
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
colon cancer 2 | 1,478
fibroadenoma 2 | 559
interstitial lung disease 2 | 298
limb girdle muscular dystrophy 2B 2 | 40
medulloblastoma 2 | 720
muscle degeneration 2 | 139
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
posterior fossa group B ependymoma 2 | 416
spina bifida 2 | 1,074

Tissue

Digestive Tract 36 | 17,369
Endocrine System 36 | 18,159
Female tissues 36 | 17,400
Liver and Pancreas 36 | 16,750
Male tissues 36 | 17,142
Nervous System 36 | 16,725
Respiratory system 36 | 16,393
Skin and soft tissues 36 | 17,230
Urinary Tract 36 | 16,678
Blood and immune system 34 | 16,909
Cardiovascular System 34 | 15,192

Target Family

Non-IDG 29 | 12,091
Enzyme 3 | 4,145
Epigenetic 1 | 242
GPCR 1 | 408
Ion Channel 1 | 344
Transcription Factor 1 | 1,400

Compartment GO Term

Cell cortex region 36 | 36
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nuclear mitotic apparatus protein 1 NUMA1 Tbio Non-IDG -2.76544 575.8 235
Pleckstrin homology-like domain family B member 1 PHLDB1 Tbio Non-IDG -0.86968 6.63 56
Suppressor APC domain-containing protein 2 SAPCD2 Tbio Non-IDG -1.10655 16.6 38
Adhesion G protein-coupled receptor A2 ADGRA2 Tbio GPCR -1.45203 30.0 211
Polycystin-2 PKD2 Tchem Ion Channel -2.63806 461.3 231
Endosialin CD248 Tbio Non-IDG -3.07620 1180.8 253
Rho guanine nucleotide exchange factor 17 ARHGEF17 Tbio Non-IDG -1.38408 25.0 61
ERC protein 2 ERC2 Tbio Non-IDG -1.60862 40.7 36
Protein bassoon BSN Tbio Non-IDG -3.05805 1116.2 84
Protein piccolo PCLO Tbio Non-IDG -2.48756 308.4 124