Development Level

Tbio 112 | 11,445
Tchem 14 | 1,598
Tdark 7 | 6,588
Tclin 5 | 613

IMPC Phenotype

preweaning lethality, complete... 13 | 979
preweaning lethality, incomple... 12 | 499
decreased body weight 6 | 161
abnormal embryo size 5 | 220
embryonic lethality prior to o... 5 | 239
embryonic lethality prior to t... 4 | 278
abnormal behavior 3 | 298
abnormal cranium morphology 3 | 36
abnormal embryo turning 3 | 31
decreased caudal vertebrae num... 3 | 53
decreased circulating HDL chol... 3 | 68
decreased circulating LDL chol... 3 | 38
decreased circulating serum al... 3 | 82
decreased mean corpuscular vol... 3 | 79
enlarged heart 3 | 210
increased bone mineral content 3 | 108
increased circulating alkaline... 3 | 122
increased circulating chloride... 3 | 41
increased lean body mass 3 | 172
prolonged QT interval 3 | 38
prolonged ST segment 3 | 36
short tibia 3 | 97
abnormal coat appearance 2 | 31
abnormal locomotor activation 2 | 16
abnormal nail morphology 2 | 8
abnormal retina morphology 2 | 71
cataract 2 | 92
decreased bone mineral content 2 | 151
decreased circulating alanine ... 2 | 47
decreased circulating calcium ... 2 | 36
decreased circulating choleste... 2 | 93
decreased circulating total pr... 2 | 49
decreased grip strength 2 | 116
decreased startle reflex 2 | 75
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
embryonic growth retardation 2 | 106
enlarged kidney 2 | 14
hypoactivity 2 | 132
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
increased circulating creatini... 2 | 38
increased circulating phosphat... 2 | 26
increased circulating sodium l... 2 | 71
pallor 2 | 34
tremors 2 | 39
abnormal behavioral response t... 1 | 66
abnormal ear morphology 1 | 9
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal pancreas morphology 1 | 13
abnormal retinal inner nuclear... 1 | 8
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
absent startle reflex 1 | 24
cardiovascular system phenotyp... 1 | 36
decreased body length 1 | 101
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased circulating glycerol... 1 | 16
decreased circulating phosphat... 1 | 27
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased lactate dehydrogenas... 1 | 16
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
decreased total retina thickne... 1 | 17
enlarged uterus 1 | 11
improved glucose tolerance 1 | 79
increased bone mineral density 1 | 72
increased circulating calcium ... 1 | 34
increased circulating iron lev... 1 | 30
increased circulating total pr... 1 | 28
increased heart weight 1 | 62
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
male infertility 1 | 123
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
prenatal lethality prior to he... 1 | 87
small spleen 1 | 19
small superior vagus ganglion 1 | 74
thin ventricular wall 1 | 24

Disease

Carcinoma 114 | 11,493
ovarian cancer 85 | 8,520
osteosarcoma 80 | 7,950
glioblastoma 67 | 5,792
medulloblastoma, large-cell 65 | 6,241
psoriasis 63 | 6,694
ependymoma 58 | 4,679
atypical teratoid / rhabdoid tumor 57 | 5,112
lung cancer 49 | 4,740
Astrocytoma, Pilocytic 46 | 3,081
group 3 medulloblastoma 46 | 4,104
Kidney cancer 44 | 2,613
adult high grade glioma 43 | 3,801
oligodendroglioma 43 | 2,850
pancreatic cancer 43 | 2,398
primitive neuroectodermal tumor 42 | 3,035
Breast cancer 41 | 3,578
astrocytic glioma 38 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 38 | 3,291
subependymal giant cell astrocytoma 38 | 2,287
Cancer 37 | 2,499
intraductal papillary-mucinous carcinoma (IPMC) 37 | 2,989
invasive ductal carcinoma 37 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 33 | 2,955
lung adenocarcinoma 31 | 2,716
ductal carcinoma in situ 30 | 1,745
non-small cell lung cancer 30 | 2,890
diabetes mellitus 29 | 1,728
lung carcinoma 27 | 2,843
malignant mesothelioma 27 | 3,232
breast carcinoma 26 | 1,638
interstitial cystitis 25 | 2,312
primary pancreatic ductal adenocarcinoma 25 | 1,109
Pick disease 24 | 1,894
acute quadriplegic myopathy 22 | 1,158
Schizophrenia 20 | 1,160
group 4 medulloblastoma 19 | 1,855
juvenile dermatomyositis 19 | 1,187
Duchenne muscular dystrophy 18 | 601
Multiple myeloma 17 | 1,332
colon cancer 17 | 1,478
pituitary cancer 17 | 1,972
tuberculosis 17 | 2,010
Alzheimer's disease 16 | 658
Autosomal recessive predisposition 16 | 1,442
adrenocortical carcinoma 16 | 1,428
ulcerative colitis 16 | 1,819
Rheumatoid arthritis 15 | 1,191
autosomal dominant Emery-Dreifuss muscular dystrophy 15 | 510
dermatomyositis 15 | 966
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
Liver cancer 14 | 604
Melanoma 14 | 711
Waldenstrons macroglobulinemia 14 | 765
Down syndrome 13 | 499
Hypertension 13 | 396
astrocytoma 13 | 1,146
progressive supranuclear palsy 13 | 676
Osteoporosis 12 | 363
Amyotrophic lateral sclerosis 11 | 451
Epilepsy 11 | 792
Liver Cirrhosis, Experimental 11 | 769
Skin cancer 11 | 469
cystic fibrosis 11 | 1,696
Anemia 10 | 365
Heart disease 10 | 306
active ulcerative colitis 10 | 764
esophageal adenocarcinoma 10 | 737
non primary Sjogren syndrome sicca 10 | 891
Cerebrovascular disease 9 | 238
Gaucher disease type 1 9 | 180
Hereditary elliptocytosis 9 | 22
Intellectual disability 9 | 1,016
Neuropathy 9 | 261
active Crohn's disease 9 | 922
cutaneous lupus erythematosus 9 | 1,057
gastric carcinoma 9 | 807
pancreatic carcinoma 9 | 562
spina bifida 9 | 1,074
Becker muscular dystrophy 8 | 191
Breast Neoplasms 8 | 445
Endometrial cancer 8 | 311
Kidney disease 8 | 430
Polycystic ovary syndrome 8 | 360
Short stature 8 | 531
mucosa-associated lymphoid tissue lymphoma 8 | 484
pediatric high grade glioma 8 | 1,064
sarcoidosis 8 | 370
Anemia, Hemolytic 7 | 55
Atopic dermatitis 7 | 952
Bipolar Disorder 7 | 666
Mammary Neoplasms 7 | 425
Myopathy 7 | 185
Neurodegenerative disease 7 | 414
Vascular disease 7 | 319
chronic rhinosinusitis 7 | 512
fibroadenoma 7 | 559
medulloblastoma 7 | 720
Mental and motor retardation 6 | 608
gastric cancer 6 | 459

Tissue

Endocrine System 137 | 18,159
Skin and soft tissues 136 | 17,230
Female tissues 135 | 17,400
Blood and immune system 134 | 16,909
Digestive Tract 134 | 17,369
Liver and Pancreas 134 | 16,750
Nervous System 132 | 16,725
Respiratory system 132 | 16,393
Urinary Tract 132 | 16,678
Male tissues 130 | 17,142
Cardiovascular System 127 | 15,192

Target Family

Non-IDG 112 | 12,091
Enzyme 17 | 4,145
Ion Channel 3 | 344
GPCR 2 | 408
Kinase 2 | 634
Transporter 2 | 473

Compartment GO Term

Cell cortex part 138 | 138
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Moesin MSN Tbio Non-IDG -2.61389 361.7 550
Nuclear mitotic apparatus protein 1 NUMA1 Tbio Non-IDG -2.76544 575.8 235
LIM and SH3 domain protein 1 LASP1 Tbio Non-IDG -1.87137 77.5 299
Exocyst complex component 3-like protein EXOC3L1 Tdark Non-IDG 0.10 1.30 62
Pleckstrin homology-like domain family B member 1 PHLDB1 Tbio Non-IDG -0.86968 6.63 56
Suppressor APC domain-containing protein 2 SAPCD2 Tbio Non-IDG -1.10655 16.6 38
Ankyrin-2 ANK2 Tbio Non-IDG -2.08421 120.5 236
Septin-9 SEPT9 Tbio Non-IDG -2.20898 161.9 130
Transient receptor potential cation channel subfamily V member 4 TRPV4 Tchem Ion Channel -2.86016 747.3 258
Septin-5 SEPT5 Tbio Non-IDG -1.71017 49.4 178