Development Level

Tbio 163 | 11,651
Tchem 40 | 1,388
Tclin 37 | 612
Tdark 11 | 6,593

Collection

Ion Channel: IDG Consortium (T... 3 | 99
RFA-RM-18-021 3 | 328

IMPC Phenotype

preweaning lethality, complete... 15 | 979
abnormal behavior 11 | 298
preweaning lethality, incomple... 9 | 499
decreased grip strength 7 | 116
decreased lean body mass 7 | 135
hyperactivity 7 | 148
impaired glucose tolerance 7 | 75
increased total body fat amoun... 7 | 134
abnormal locomotor behavior 6 | 24
increased circulating sodium l... 6 | 71
decreased circulating alkaline... 5 | 46
decreased fasted circulating g... 5 | 65
decreased total body fat amoun... 5 | 207
increased circulating alkaline... 5 | 122
abnormal bone structure 4 | 187
decreased circulating glucose ... 4 | 126
edema 4 | 59
hypoactivity 4 | 132
increased circulating chloride... 4 | 41
prolonged QT interval 4 | 38
prolonged ST segment 4 | 36
abnormal gait 3 | 69
abnormal sleep behavior 3 | 70
decreased bone mineral content 3 | 151
decreased bone mineral density 3 | 126
decreased circulating serum al... 3 | 82
decreased vertical activity 3 | 208
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
increased fasted circulating g... 3 | 76
increased lean body mass 3 | 172
short tibia 3 | 97
tremors 3 | 39
abnormal behavioral response t... 2 | 66
abnormal epididymis morphology 2 | 42
abnormal retina morphology 2 | 71
decreased basophil cell number 2 | 16
decreased body length 2 | 101
decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
decreased circulating insulin ... 2 | 76
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased lymphocyte cell numb... 2 | 83
decreased pulmonary respirator... 2 | 5
decreased startle reflex 2 | 75
enlarged stomach 2 | 2
hemorrhage 2 | 23
improved glucose tolerance 2 | 79
increased blood urea nitrogen ... 2 | 48
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased circulating amylase ... 2 | 25
increased mean corpuscular hem... 2 | 96
increased red blood cell distr... 2 | 34
increased spleen weight 2 | 10
increased startle reflex 2 | 112
limb grasping 2 | 41
small thymus 2 | 16
thrombocytosis 2 | 27
abnormal cranium morphology 1 | 36
abnormal hair growth 1 | 10
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal spine curvature 1 | 9
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
convulsive seizures 1 | 13
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating magnesiu... 1 | 13
decreased circulating potassiu... 1 | 20
decreased circulating sodium l... 1 | 22
decreased eosinophil cell numb... 1 | 24
decreased food intake 1 | 13
decreased neutrophil cell numb... 1 | 42
enlarged epididymis 1 | 31
impaired righting response 1 | 26
increased anti-nuclear antigen... 1 | 19
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased prepulse inhibition 1 | 32
premature death 1 | 5
small testis 1 | 58
thin ventricular wall 1 | 24

Disease

Carcinoma 170 | 11,493
glioblastoma 136 | 5,792
atypical teratoid / rhabdoid tumor 131 | 5,112
medulloblastoma, large-cell 129 | 6,241
ependymoma 121 | 4,679
adult high grade glioma 110 | 3,801
psoriasis 105 | 6,694
Astrocytoma, Pilocytic 102 | 3,081
osteosarcoma 99 | 7,950
oligodendroglioma 98 | 2,850
ovarian cancer 98 | 8,520
Schizophrenia 89 | 1,160
group 3 medulloblastoma 86 | 4,104
primitive neuroectodermal tumor 83 | 3,035
lung cancer 77 | 4,740
astrocytic glioma 76 | 2,597
Cancer 73 | 2,499
Bipolar Disorder 65 | 666
Alzheimer's disease 60 | 658
Breast cancer 58 | 3,578
Kidney cancer 58 | 2,613
Pick disease 58 | 1,894
Depressive disorder 56 | 409
pituitary cancer 55 | 1,972
intraductal papillary-mucinous carcinoma (IPMC) 54 | 2,989
malignant mesothelioma 54 | 3,232
subependymal giant cell astrocytoma 54 | 2,287
Parkinson's disease 53 | 392
intraductal papillary-mucinous neoplasm (IPMN) 53 | 3,291
lung carcinoma 53 | 2,843
intraductal papillary-mucinous adenoma (IPMA) 52 | 2,955
Epilepsy 51 | 792
Mental Depression 48 | 333
invasive ductal carcinoma 47 | 2,951
Neurodegenerative disease 42 | 414
diabetes mellitus 42 | 1,728
Seizures 41 | 596
Alcoholic Intoxication, Chronic 40 | 289
colon cancer 40 | 1,478
group 4 medulloblastoma 39 | 1,855
Obesity 37 | 678
Toxic encephalopathy 37 | 141
lung adenocarcinoma 36 | 2,716
Major Depressive Disorder 35 | 301
cystic fibrosis 34 | 1,696
non-small cell lung cancer 34 | 2,890
Down syndrome 33 | 499
interstitial cystitis 32 | 2,312
Intellectual disability 31 | 1,016
Dementia 30 | 175
astrocytoma 30 | 1,146
Mood Disorders 29 | 184
Unipolar Depression 29 | 250
pancreatic cancer 29 | 2,398
Autosomal recessive predisposition 28 | 1,442
Cerebrovascular disease 28 | 238
Neuropathy 26 | 261
adrenocortical carcinoma 26 | 1,428
Autistic Disorder 25 | 364
ulcerative colitis 25 | 1,819
Hypertension 24 | 396
Amyotrophic lateral sclerosis 23 | 451
Melanoma 23 | 711
Multiple Sclerosis 23 | 540
Pain agnosia 23 | 104
tuberculosis 23 | 2,010
Cocaine-Related Disorders 21 | 92
Liver cancer 21 | 604
Pain 21 | 103
Brain disease 20 | 96
Nerve Degeneration 20 | 121
breast carcinoma 20 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,962
pediatric high grade glioma 20 | 1,064
Skin cancer 19 | 469
Constipation 18 | 181
Huntington's disease 18 | 76
Hyperalgesia 18 | 83
Migraine 18 | 83
cutaneous lupus erythematosus 18 | 1,057
ductal carcinoma in situ 18 | 1,745
non primary Sjogren syndrome sicca 18 | 891
Alcohol dependence 17 | 107
Asthma 17 | 385
Endometriosis 17 | 540
Parkinsonian Disorders 17 | 56
aldosterone-producing adenoma 17 | 665
spina bifida 17 | 1,074
Cognitive delay 16 | 608
Global developmental delay 16 | 608
Mental and motor retardation 16 | 608
Multiple myeloma 16 | 1,332
acute quadriplegic myopathy 16 | 1,158
juvenile dermatomyositis 16 | 1,187
progressive supranuclear palsy 16 | 676
Atopic dermatitis 15 | 952
Attention deficit hyperactivity disorder 15 | 278
Duchenne muscular dystrophy 15 | 601
Mental deficiency 14 | 645
Poor school performance 14 | 645

Tissue

Endocrine System 246 | 18,159
Female tissues 240 | 17,400
Nervous System 239 | 16,725
Skin and soft tissues 238 | 17,230
Digestive Tract 237 | 17,369
Male tissues 234 | 17,142
Liver and Pancreas 229 | 16,750
Blood and immune system 224 | 16,909
Urinary Tract 222 | 16,678
Respiratory system 212 | 16,393
Cardiovascular System 192 | 15,192

Target Family

Non-IDG 149 | 12,091
Enzyme 35 | 4,145
Ion Channel 31 | 344
Transporter 12 | 473
Kinase 11 | 634
GPCR 7 | 408
Epigenetic 4 | 242
Transcription Factor 2 | 1,400

Compartment GO Term

Cell body 251 | 251
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium-dependent serotonin transporter SLC6A4 Tclin Transporter -3.63283 4453.8 245
Synphilin-1 SNCAIP Tbio Non-IDG -1.92755 92.1 157
Phosphatidylinositol 4-kinase type 2-alpha PI4K2A Tbio Kinase -2.88003 745.1 146
Copine-5 CPNE5 Tbio Non-IDG -0.45967 3.10 91
C-C chemokine receptor type 2 CCR2 Tchem GPCR -3.06548 1112.4 530
Amphoterin-induced protein 1 AMIGO1 Tbio Non-IDG -1.74542 52.4 221
Double-stranded RNA-binding protein Staufen homolog 1 STAU1 Tbio Non-IDG -2.24156 174.1 258
Low affinity immunoglobulin gamma Fc region receptor II-b FCGR2B Tbio Non-IDG -2.61667 619.4 476
Noelin OLFM1 Tbio Non-IDG -1.29218 21.3 300
Netrin receptor UNC5A UNC5A Tbio Non-IDG -1.25948 14.2 74