Development Level

Tbio 182 | 11,445
Tdark 50 | 6,588
Tchem 25 | 1,598
Tclin 6 | 613

Collection

Kinase: IDG Consortium (Target... 4 | 125
Ion Channel: IDG Consortium (T... 2 | 99
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 21 | 979
preweaning lethality, incomple... 8 | 499
abnormal behavior 6 | 298
embryonic lethality prior to t... 6 | 278
abnormal embryo size 5 | 220
decreased bone mineral content 5 | 151
decreased lean body mass 5 | 135
decreased total body fat amoun... 5 | 207
decreased vertical activity 5 | 208
enlarged heart 5 | 210
hyperactivity 5 | 148
increased or absent threshold ... 5 | 101
decreased body length 4 | 101
embryonic lethality prior to o... 4 | 239
increased lean body mass 4 | 172
short tibia 4 | 97
abnormal bone structure 3 | 187
abnormal coat-hair pigmentatio... 3 | 64
abnormal cranium morphology 3 | 36
abnormal gait 3 | 69
abnormal retina morphology 3 | 71
decreased bone mineral density 3 | 126
decreased circulating total pr... 3 | 49
decreased leukocyte cell numbe... 3 | 73
hypoactivity 3 | 132
increased bone mineral content 3 | 108
increased heart weight 3 | 62
male infertility 3 | 123
prenatal lethality prior to he... 3 | 87
abnormal behavioral response t... 2 | 66
abnormal brain morphology 2 | 13
abnormal craniofacial morpholo... 2 | 33
abnormal ear morphology 2 | 9
abnormal eye morphology 2 | 68
abnormal heart morphology 2 | 162
abnormal lung morphology 2 | 26
abnormal neural tube closure 2 | 46
abnormal skin morphology 2 | 50
abnormal snout morphology 2 | 23
abnormal tail morphology 2 | 25
corneal opacity 2 | 32
cyanosis 2 | 7
decreased basophil cell number 2 | 16
decreased body weight 2 | 161
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased circulating serum al... 2 | 82
decreased eosinophil cell numb... 2 | 24
decreased grip strength 2 | 116
decreased prepulse inhibition 2 | 82
hemorrhage 2 | 23
hydroencephaly 2 | 14
impaired glucose tolerance 2 | 75
increased bone mineral density 2 | 72
increased circulating alkaline... 2 | 122
increased fasted circulating g... 2 | 76
increased mean corpuscular vol... 2 | 92
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
limb grasping 2 | 41
pale yolk sac 2 | 25
thrombocytosis 2 | 27
abnormal cornea morphology 1 | 31
abnormal hair growth 1 | 10
abnormal head morphology 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal neural tube morpholog... 1 | 12
abnormal optic disc morphology 1 | 10
abnormal placenta size 1 | 20
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal tail movements 1 | 12
abnormal tooth morphology 1 | 24
abnormal vitreous body morphol... 1 | 10
absent startle reflex 1 | 24
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased red blood cell distr... 1 | 41
dilated heart left ventricle 1 | 11
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
hydrometra 1 | 53
impaired righting response 1 | 26
increased body length 1 | 32
increased body weight 1 | 25
increased circulating phosphat... 1 | 26
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
prenatal lethality 1 | 28

Disease

Carcinoma 176 | 11,493
ovarian cancer 146 | 8,520
osteosarcoma 128 | 7,950
medulloblastoma, large-cell 107 | 6,241
glioblastoma 102 | 5,792
psoriasis 101 | 6,694
atypical teratoid / rhabdoid tumor 92 | 5,112
ependymoma 92 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 74 | 3,291
lung cancer 74 | 4,740
adult high grade glioma 71 | 3,801
malignant mesothelioma 71 | 3,232
primitive neuroectodermal tumor 70 | 3,035
Breast cancer 68 | 3,578
group 3 medulloblastoma 68 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 67 | 2,989
non-small cell lung cancer 64 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 61 | 2,955
Kidney cancer 59 | 2,613
lung carcinoma 59 | 2,843
Astrocytoma, Pilocytic 58 | 3,081
lung adenocarcinoma 58 | 2,716
interstitial cystitis 56 | 2,312
invasive ductal carcinoma 56 | 2,951
oligodendroglioma 52 | 2,850
astrocytic glioma 51 | 2,597
subependymal giant cell astrocytoma 48 | 2,287
Cancer 47 | 2,499
pancreatic cancer 47 | 2,398
ductal carcinoma in situ 45 | 1,745
pituitary cancer 41 | 1,972
Pick disease 39 | 1,894
group 4 medulloblastoma 37 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 37 | 1,962
spina bifida 36 | 1,074
cystic fibrosis 32 | 1,696
tuberculosis 32 | 2,010
breast carcinoma 28 | 1,638
Rheumatoid arthritis 27 | 1,191
ulcerative colitis 26 | 1,819
colon cancer 25 | 1,478
juvenile dermatomyositis 25 | 1,187
Schizophrenia 24 | 1,160
acute quadriplegic myopathy 24 | 1,158
cutaneous lupus erythematosus 24 | 1,057
nasopharyngeal carcinoma 23 | 1,058
gastric carcinoma 22 | 807
adrenocortical carcinoma 21 | 1,428
dermatomyositis 21 | 966
esophageal adenocarcinoma 21 | 737
pediatric high grade glioma 19 | 1,064
acute myeloid leukemia 18 | 783
diabetes mellitus 18 | 1,728
primary pancreatic ductal adenocarcinoma 18 | 1,109
Melanoma 17 | 711
non primary Sjogren syndrome sicca 17 | 891
Autosomal recessive predisposition 16 | 1,442
Down syndrome 16 | 499
Duchenne muscular dystrophy 16 | 601
astrocytoma 16 | 1,146
Liver Cirrhosis, Experimental 15 | 769
Liver cancer 15 | 604
Prostatic Neoplasms 15 | 495
Atopic dermatitis 14 | 952
Bipolar Disorder 14 | 666
active Crohn's disease 14 | 922
active ulcerative colitis 14 | 764
Skin cancer 13 | 469
medulloblastoma 12 | 720
Amyotrophic lateral sclerosis 11 | 451
Endometriosis 11 | 540
Intellectual disability 11 | 1,016
aldosterone-producing adenoma 11 | 665
fibroadenoma 11 | 559
Alzheimer's disease 10 | 658
Autistic Disorder 10 | 364
Epilepsy 10 | 792
Multiple myeloma 10 | 1,332
Waldenstrons macroglobulinemia 10 | 765
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 510
Neurodegenerative disease 9 | 414
atypical teratoid/rhabdoid tumor 9 | 357
chronic rhinosinusitis 9 | 512
interstitial lung disease 9 | 298
progressive supranuclear palsy 9 | 676
Atherosclerosis 8 | 291
Breast Neoplasms 8 | 445
Parkinson's disease 8 | 392
gastric cancer 8 | 459
Cerebrovascular disease 7 | 238
Chronic Lymphocytic Leukemia 7 | 262
Cognitive delay 7 | 608
Global developmental delay 7 | 608
Kidney disease 7 | 430
Mental and motor retardation 7 | 608
Short stature 7 | 531
Small head 7 | 374
mucosa-associated lymphoid tissue lymphoma 7 | 484
pancreatic carcinoma 7 | 562
primary Sjogren syndrome 7 | 735

Tissue

Endocrine System 263 | 18,159
Urinary Tract 263 | 16,678
Digestive Tract 262 | 17,369
Female tissues 262 | 17,400
Male tissues 262 | 17,142
Liver and Pancreas 261 | 16,750
Skin and soft tissues 261 | 17,230
Respiratory system 260 | 16,393
Blood and immune system 259 | 16,909
Nervous System 255 | 16,725
Cardiovascular System 242 | 15,192

Target Family

Non-IDG 173 | 12,091
Enzyme 38 | 4,145
Kinase 19 | 634
Transporter 17 | 473
Transcription Factor 7 | 1,400
GPCR 4 | 408
Ion Channel 4 | 344
Nuclear Receptor 1 | 48

Compartment GO Term

Cell Junctions 263 | 263
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein 236 ZNF236 Tbio Transcription Factor -0.40816 2.56 30
Protein Shroom2 SHROOM2 Tbio Non-IDG -1.07032 11.9 112
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 MAGI1 Tbio Enzyme -1.08587 12.0 153
CDK5 and ABL1 enzyme substrate 2 CABLES2 Tdark Non-IDG 0.08 1.29 75
Junctional adhesion molecule A F11R Tbio Non-IDG -2.56739 380.0 394
Glucose-induced degradation protein 8 homolog GID8 Tbio Non-IDG -0.78882 6.72 123
Feline leukemia virus subgroup C receptor-related protein 1 FLVCR1 Tbio Non-IDG -1.54460 33.8 139
RNA pseudouridylate synthase domain-containing protein 1 RPUSD1 Tdark Enzyme 1.30 0.03 64
Plakophilin-2 PKP2 Tbio Non-IDG -2.10355 135.3 243
Apoptosis-stimulating of p53 protein 2 TP53BP2 Tbio Non-IDG -1.85307 72.5 189