Development Level

Tbio 70 | 10,625
Tdark 14 | 7,003
Tchem 6 | 1,890

Collection

Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

preweaning lethality, complete... 7 | 633
embryonic lethality prior to o... 3 | 148
embryonic lethality prior to t... 3 | 187
decreased leukocyte cell numbe... 2 | 54
decreased neutrophil cell numb... 2 | 37
thrombocytosis 2 | 23
abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal lung morphology 1 | 15
abnormal pancreas morphology 1 | 6
abnormal retina morphology 1 | 100
absent pinna reflex 1 | 21
cardiovascular system phenotyp... 1 | 35
decreased CD5-positive gamma-d... 1 | 3
decreased KLRG1-positive NK ce... 1 | 9
decreased Ly6C high monocyte n... 1 | 18
decreased Ly6C low monocyte nu... 1 | 23
decreased body length 1 | 108
decreased cervical vertebrae n... 1 | 12
decreased circulating calcium ... 1 | 33
decreased circulating glucose ... 1 | 121
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
decreased lymphocyte cell numb... 1 | 9
decreased monocyte cell number 1 | 28
enlarged heart 1 | 111
female infertility 1 | 34
hyperactivity 1 | 108
impaired righting response 1 | 19
increased circulating HDL chol... 1 | 63
increased circulating alkaline... 1 | 119
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating free fat... 1 | 17
increased circulating serum al... 1 | 25
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased or absent threshold ... 1 | 128
increased rib number 1 | 41
male infertility 1 | 62
oligodactyly 1 | 14
preweaning lethality, incomple... 1 | 260
sparse hair 1 | 6

Disease

ovarian cancer 63 | 8,491
osteosarcoma 37 | 7,933
medulloblastoma, large-cell 33 | 6,234
psoriasis 31 | 6,685
group 3 medulloblastoma 29 | 2,254
Multiple myeloma 26 | 1,327
lung cancer 25 | 4,473
glioblastoma 24 | 5,572
acute quadriplegic myopathy 20 | 1,157
astrocytoma 18 | 1,493
malignant mesothelioma 18 | 3,163
Waldenstrons macroglobulinemia 17 | 764
atypical teratoid / rhabdoid tumor 17 | 4,369
diabetes mellitus 17 | 1,663
oligodendroglioma 17 | 2,849
ependymoma 16 | 2,514
dermatomyositis 14 | 966
primitive neuroectodermal tumor 13 | 3,031
Breast cancer 12 | 3,098
Cancer 10 | 2,346
Carcinoma 10 | 2,147
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,289
Pick disease 9 | 1,893
atypical teratoid/rhabdoid tumor 9 | 1,095
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
sonic hedgehog group medulloblastoma 9 | 1,482
acute myeloid leukemia 8 | 785
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,988
progressive supranuclear palsy 8 | 674
Amyotrophic Lateral Sclerosis 7 | 432
lung adenocarcinoma 7 | 2,714
pediatric high grade glioma 7 | 2,712
HIV Infections 6 | 99
Intellectual disability 6 | 573
astrocytic glioma 6 | 2,241
invasive ductal carcinoma 6 | 2,950
juvenile dermatomyositis 6 | 1,189
non-small cell lung cancer 6 | 2,798
pancreatic cancer 6 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
subependymal giant cell astrocytoma 6 | 2,287
tuberculosis and treatment for 6 months 6 | 686
Gaucher disease type 1 5 | 171
adult high grade glioma 5 | 2,148
hepatocellular carcinoma 5 | 550
Retinitis pigmentosa 4 | 156
Rheumatoid Arthritis 4 | 1,170
Spinal muscular atrophy 4 | 24
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 499
gastric cancer 4 | 436
glioblastoma multiforme 4 | 347
medulloblastoma 4 | 1,524
nasopharyngeal carcinoma 4 | 1,056
non primary Sjogren syndrome sicca 4 | 840
Acquired immunodeficiency syndrome 3 | 164
Atopic dermatitis 3 | 944
Down syndrome 3 | 548
Frontotemporal dementia 3 | 47
Immune system cancer 3 | 38
Lupus erythematosus 3 | 80
Mammary Neoplasms 3 | 410
Microcephaly 3 | 149
Polycystic Ovary Syndrome 3 | 334
Subcutaneous panniculitis-like T-cell lymphoma 3 | 16
breast carcinoma 3 | 1,614
cystic fibrosis 3 | 1,670
hereditary spastic paraplegia 3 | 313
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,271
Animal Mammary Neoplasms 2 | 135
Chronic obstructive pulmonary disease 2 | 147
Cockayne syndrome 2 | 54
Disease Progression 2 | 125
Duchenne muscular dystrophy 2 | 602
Epilepsy 2 | 346
Hematologic cancer 2 | 9
Kidney disease 2 | 397
MYELODYSPLASTIC SYNDROME 2 | 39
Mammary Neoplasms, Experimental 2 | 149
Melanoma 2 | 261
Multiple Sclerosis 2 | 498
Nager acrofacial dysostosis 2 | 21
Osteoporosis 2 | 259
Schizophrenia 2 | 503
Stomach Neoplasms 2 | 282
Thrombocytopenia 2 | 105
adrenocortical carcinoma 2 | 1,427
aldosterone-producing adenoma 2 | 664
colon cancer 2 | 1,475
group 4 medulloblastoma 2 | 1,875
non diabetic and post-ischemic heart failure 2 | 200
pancreatic carcinoma 2 | 567
posterior fossa group B ependymoma 2 | 1,530
primary Sjogren syndrome 2 | 788
relapsing-remitting multiple sclerosis 2 | 18
spina bifida 2 | 1,064
tuberculosis and treatment for 3 months 2 | 327
Agoraphobia 1 | 16
Cone dystrophy 1 | 59
Radioulnar synostosis 1 | 13

Tissue

Blood and immune system 88 | 17,994
Cardiovascular System 88 | 17,957
Digestive Tract 88 | 18,472
Endocrine System 88 | 18,511
Female tissues 88 | 18,646
Liver and Pancreas 88 | 18,135
Male tissues 88 | 17,968
Nervous System 88 | 18,560
Respiratory system 88 | 17,483
Urinary Tract 88 | 18,443
Skin and soft tissues 87 | 18,114

Target Family

Non-IDG 75 | 11,969
Enzyme 12 | 4,146
Epigenetic 1 | 242
Kinase 1 | 634
Transcription Factor 1 | 1,400

Compartment GO Term

Catalytic step 2 spliceosome 90 | 90
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
RNA-binding motif protein, X chromosome RBMX Tbio Non-IDG -1.49173 32.8 82
Peptidyl-prolyl cis-trans isomerase E PPIE Tbio Enzyme -1.30532 19.4 143
Pleiotropic regulator 1 PLRG1 Tbio Non-IDG -0.93540 8.69 172
Small nuclear ribonucleoprotein-associated protein N SNURF Tbio Non-IDG -1.63847 44.6 100
Pre-mRNA-processing factor 6 PRPF6 Tbio Non-IDG -1.35844 27.6 163
Pre-mRNA-splicing factor ISY1 homolog ISY1 Tdark Non-IDG 0.00000 24
Heterogeneous nuclear ribonucleoprotein R HNRNPR Tbio Non-IDG -0.96419 10.0 120
U4/U6.U5 tri-snRNP-associated protein 1 SART1 Tbio Non-IDG -1.81163 66.1 137
Pre-mRNA-processing factor 19 PRPF19 Tbio Non-IDG -1.69580 50.3 225
Pre-mRNA-splicing factor SLU7 SLU7 Tbio Non-IDG -1.30438 19.3 179