Development Level

Tbio 33 | 11,445
Tchem 32 | 1,598
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, complete... 6 | 979
decreased circulating insulin ... 3 | 76
embryonic lethality prior to t... 3 | 278
abnormal seminal vesicle morph... 2 | 114
abnormal testis morphology 2 | 43
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
enlarged heart 2 | 210
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
preweaning lethality, incomple... 2 | 499
small testis 2 | 58
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal heart morphology 1 | 162
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal retinal inner nuclear... 1 | 8
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
absent testes 1 | 6
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased heart left ventricle... 1 | 28
decreased lean body mass 1 | 135
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
increased basophil cell number 1 | 7
increased circulating glucose ... 1 | 24
increased eosinophil cell numb... 1 | 11
increased large unstained cell... 1 | 5
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
small seminal vesicle 1 | 10
small superior vagus ganglion 1 | 74
urinary bladder obstruction 1 | 4

Disease

Cancer 57 | 2,499
ovarian cancer 45 | 8,520
lung cancer 41 | 4,740
osteosarcoma 40 | 7,950
psoriasis 39 | 6,694
Carcinoma 36 | 11,493
glioblastoma 33 | 5,792
malignant mesothelioma 26 | 3,232
medulloblastoma, large-cell 26 | 6,241
atypical teratoid / rhabdoid tumor 23 | 5,112
pancreatic cancer 23 | 2,398
diabetes mellitus 22 | 1,728
Vascular disease 21 | 319
lung carcinoma 21 | 2,843
subependymal giant cell astrocytoma 21 | 2,287
group 3 medulloblastoma 20 | 4,104
Astrocytoma, Pilocytic 19 | 3,081
tuberculosis 19 | 2,010
Toxic encephalopathy 18 | 141
adult high grade glioma 18 | 3,801
ependymoma 18 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
Breast cancer 17 | 3,578
non-small cell lung cancer 17 | 2,890
ulcerative colitis 17 | 1,819
Arthritis 16 | 290
cutaneous lupus erythematosus 16 | 1,057
Hypersensitivity reaction type II disease 15 | 253
Kidney disease 15 | 430
Schizophrenia 15 | 1,160
hepatocellular carcinoma 15 | 547
lung adenocarcinoma 15 | 2,716
Alzheimer's disease 14 | 658
Breast Neoplasms 14 | 445
Mammary Neoplasms 14 | 425
Stomach Neoplasms 14 | 300
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
invasive ductal carcinoma 14 | 2,951
oligodendroglioma 14 | 2,850
Liver Cirrhosis, Experimental 13 | 769
Lung Neoplasms 13 | 232
Obesity 13 | 678
Prostatic Neoplasms 13 | 495
cystic fibrosis 13 | 1,696
primitive neuroectodermal tumor 13 | 3,035
Anemia 12 | 365
Eye disease 12 | 62
Heart disease 12 | 306
Liver disease 12 | 237
Neurodegenerative disease 12 | 414
colon cancer 12 | 1,478
pituitary cancer 12 | 1,972
Bipolar Disorder 11 | 666
Inflammatory bowel disease 11 | 151
Multiple myeloma 11 | 1,332
adrenocortical carcinoma 11 | 1,428
Brain Ischemia 10 | 110
Lung disease 10 | 142
Myocardial Infarction 10 | 151
Parkinson's disease 10 | 392
Splenomegaly 10 | 190
interstitial cystitis 10 | 2,312
juvenile dermatomyositis 10 | 1,187
Brain disease 9 | 96
Carcinoma, Hepatocellular 9 | 228
Colonic Neoplasms 9 | 142
Kidney cancer 9 | 2,613
Liver carcinoma 9 | 240
Multiple Sclerosis 9 | 540
Myocardial Reperfusion Injury 9 | 37
breast carcinoma 9 | 1,638
gastric cancer 9 | 459
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
pancreatic carcinoma 9 | 562
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
primary pancreatic ductal adenocarcinoma 9 | 1,109
Colorectal Neoplasms 8 | 243
Diabetes Mellitus, Experimental 8 | 108
Fever 8 | 138
Pneumonia 8 | 174
Rheumatoid arthritis 8 | 1,191
Urticaria 8 | 67
active Crohn's disease 8 | 922
acute quadriplegic myopathy 8 | 1,158
astrocytic glioma 8 | 2,597
mucosa-associated lymphoid tissue lymphoma 8 | 484
primary Sjogren syndrome 8 | 735
Adenocarcinoma 7 | 122
Asthma 7 | 385
Atherosclerosis 7 | 291
Diabetes Mellitus, Type 2 7 | 142
Melanoma 7 | 711
Vasculitis 7 | 80
active ulcerative colitis 7 | 764
acute myeloid leukemia 7 | 783
astrocytoma 7 | 1,146
ductal carcinoma in situ 7 | 1,745
gastric carcinoma 7 | 807
dermatomyositis 6 | 966
spina bifida 6 | 1,074

Tissue

Blood and immune system 67 | 16,909
Digestive Tract 67 | 17,369
Endocrine System 67 | 18,159
Female tissues 66 | 17,400
Liver and Pancreas 66 | 16,750
Male tissues 66 | 17,142
Nervous System 66 | 16,725
Respiratory system 66 | 16,393
Skin and soft tissues 66 | 17,230
Urinary Tract 66 | 16,678
Cardiovascular System 64 | 15,192

Target Family

Non-IDG 42 | 12,091
Enzyme 22 | 4,145
Kinase 2 | 634
Transcription Factor 2 | 1,400

Compartment GO Term

Caspase complex 68 | 68
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phorbol-12-myristate-13-acetate-induced protein 1 PMAIP1 Tbio Non-IDG -2.70122 462.2 347
NACHT, LRR and PYD domains-containing protein 3 NLRP3 Tchem Non-IDG -3.29685 1936.6 519
Keratin, type I cytoskeletal 18 KRT18 Tbio Non-IDG -3.05211 1057.8 1953
Caspase-2 CASP2 Tchem Enzyme -2.62373 431.8 571
Serine protease HTRA2, mitochondrial HTRA2 Tbio Enzyme -2.60032 392.5 519
Pyrin MEFV Tbio Non-IDG -3.02735 980.3 176
Caspase-4 CASP4 Tchem Enzyme -2.19377 147.3 520
Cytochrome c CYCS Tbio Non-IDG -3.76637 4945.6 833
DNA damage-inducible transcript 3 protein DDIT3 Tchem Transcription Factor -2.94434 736.0 704
Caspase-6 CASP6 Tchem Enzyme -2.49135 293.6 874