Development Level

Tbio 8 | 11,445

IMPC Phenotype

abnormal heart morphology 1 | 162
abnormal response to new envir... 1 | 10
decreased circulating amylase ... 1 | 28
decreased mean corpuscular vol... 1 | 79
increased circulating chloride... 1 | 41
increased heart weight 1 | 62
preweaning lethality, complete... 1 | 979

Disease

Dilated cardiomyopathy 7 | 56
Carcinoma 6 | 11,493
Cardiomyopathy 6 | 116
Hypertrophic Cardiomyopathy 6 | 117
Cardiomyopathy, Dilated 5 | 83
Familial isolated dilated cardiomyopathy 5 | 41
LEFT VENTRICULAR NONCOMPACTION 10 5 | 40
LEFT VENTRICULAR NONCOMPACTION 8 5 | 40
Autosomal recessive predisposition 4 | 1,442
Cardiomyopathy, Hypertrophic, Familial 4 | 9
Myopathy 4 | 185
lung cancer 4 | 4,740
pancreatic cancer 4 | 2,398
psoriasis 4 | 6,694
Bell Palsy 3 | 58
Breast cancer 3 | 3,578
Cardiomyopathies 3 | 110
Cardiomyopathy, Hypertrophic 3 | 24
Congestive heart failure 3 | 113
EMG: myopathic abnormalities 3 | 22
Facial Paresis 3 | 59
Facial muscle weakness of muscles innervated by CN VII 3 | 58
Left ventricular noncompaction 3 | 26
Primary cutaneous amyloidosis 3 | 29
lung adenocarcinoma 3 | 2,716
lung carcinoma 3 | 2,843
Acquired scoliosis 2 | 281
Acute coronary syndrome 2 | 39
Amyloidosis 2 | 67
Arrhythmogenic right ventricular cardiomyopathy 2 | 30
Atrial Fibrillation 2 | 124
Bulbar palsy 2 | 19
Bulbar weakness 2 | 19
Cardiac Arrhythmia 2 | 103
Cardiac conduction abnormalities 2 | 78
Cardiomegaly 2 | 116
Cerebrovascular disease 2 | 238
Conduction disorder of the heart 2 | 79
Coronary artery disease 2 | 268
Curvature of spine 2 | 282
Death, Sudden, Cardiac 2 | 5
Distal arthrogryposis 2 | 42
Distal limb muscle weakness due to peripheral neuropathy 2 | 62
Distal muscle weakness 2 | 62
EKG abnormalities 2 | 78
Electrocardiogram abnormal 2 | 81
Electrocardiogram change 2 | 78
Endometrial cancer 2 | 311
Foot dorsiflexor weakness 2 | 27
Foot-drop 2 | 27
Gas gangrene 2 | 17
Generalized muscle weakness 2 | 57
Heart Diseases 2 | 43
Heart disease 2 | 306
Heart failure 2 | 162
Infantile onset 2 | 238
Kidney Failure 2 | 111
Kidney cancer 2 | 2,613
Liver cancer 2 | 604
Melanoma 2 | 711
Motor delay 2 | 147
Muscle biopsy shows dystrophic changes 2 | 39
Muscular dystrophy 2 | 75
Neck flexor weakness 2 | 6
No development of motor milestones 2 | 147
Other restrictive cardiomyopathy 2 | 4
Proximal muscle weakness 2 | 47
Proximal neurogenic muscle weakness 2 | 47
Pulmonary embolism 2 | 55
Respiratory insufficiency due to muscle weakness 2 | 37
Restrictive cardiomyopathy 2 | 11
Skin cancer 2 | 469
Sudden Cardiac Death 2 | 29
Sudden death 2 | 16
Tachycardia, Ventricular 2 | 22
adult high grade glioma 2 | 3,801
colon cancer 2 | 1,478
diabetes mellitus 2 | 1,728
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
limb-girdle muscular dystrophy 2 | 37
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
ovarian cancer 2 | 8,520
primary pancreatic ductal adenocarcinoma 2 | 1,109
Congenital Fiber Type Disproportion 1 | 7
Congenital myopathy with fiber type disproportion 1 | 9
Flexion contracture - elbow 1 | 32
Frequent falls 1 | 12
Gait, Drop Foot 1 | 24
Heart Injuries 1 | 3
Hernias, Diaphragmatic, Congenital 1 | 17
Hyporeflexia of lower limbs 1 | 10
Myasthenia gravis 1 | 23
Myofibrillar Myopathy 1 | 9
Rimmed vacuoles on biopsy 1 | 15
Scapular weakness 1 | 23
Scapuloperoneal weakness 1 | 3
Ventricular hypertrophy 1 | 6
Winged scapula 1 | 23

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678
Nervous System 7 | 16,725
Respiratory system 7 | 16,393

Target Family

Non-IDG 7 | 12,091
Kinase 1 | 634

Compartment GO Term

Cardiac myofibril 8 | 8
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Desmin DES Tbio Non-IDG -1.56068 36.6 991
Titin TTN Tbio Kinase -3.24415 1743.0 123
Myosin-binding protein C, cardiac-type MYBPC3 Tbio Non-IDG -2.45618 287.6 139
Nebulette NEBL Tbio Non-IDG -1.42860 31.4 51
Nebulin NEB Tbio Non-IDG -2.48623 301.1 70
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform MYL2 Tbio Non-IDG -2.23022 155.8 222
Troponin T, cardiac muscle TNNT2 Tbio Non-IDG -3.19980 1554.3 829
Troponin I, cardiac muscle TNNI3 Tbio Non-IDG -3.55281 3485.6 1706