Development Level

Tbio 29 | 11,445
Tchem 21 | 1,598
Tclin 19 | 613
Tdark 10 | 6,588

Collection

Ion Channel: IDG Consortium (T... 13 | 99

IMPC Phenotype

preweaning lethality, complete... 12 | 979
abnormal embryo size 5 | 220
embryonic lethality prior to t... 5 | 278
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
decreased circulating glucose ... 2 | 126
decreased mean platelet volume 2 | 25
decreased neutrophil cell numb... 2 | 42
edema 2 | 59
embryonic growth retardation 2 | 106
impaired glucose tolerance 2 | 75
increased circulating sodium l... 2 | 71
increased startle reflex 2 | 112
prenatal lethality 2 | 28
prolonged ST segment 2 | 36
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal placenta vasculature 1 | 2
abnormal seminal vesicle morph... 1 | 114
abnormal sensory capabilities-... 1 | 8
absent vibrissae 1 | 12
cardiovascular system phenotyp... 1 | 36
cyanosis 1 | 7
decreased cardiac stroke volum... 1 | 6
decreased circulating alkaline... 1 | 46
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased prepulse inhibition 1 | 82
decreased vertical activity 1 | 208
enlarged spleen 1 | 41
enlarged testis 1 | 6
hemorrhage 1 | 23
hyperactivity 1 | 148
impaired righting response 1 | 26
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased respiratory quotient 1 | 2
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
long tibia 1 | 25
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
prolonged QT interval 1 | 38
respiratory system phenotype 1 | 2
small epididymis 1 | 3
small seminal vesicle 1 | 10

Disease

Carcinoma 60 | 11,493
psoriasis 38 | 6,694
medulloblastoma, large-cell 35 | 6,241
glioblastoma 34 | 5,792
osteosarcoma 32 | 7,950
ovarian cancer 32 | 8,520
adult high grade glioma 31 | 3,801
atypical teratoid / rhabdoid tumor 31 | 5,112
Kidney cancer 30 | 2,613
group 3 medulloblastoma 26 | 4,104
ependymoma 25 | 4,679
Astrocytoma, Pilocytic 22 | 3,081
Breast cancer 22 | 3,578
primitive neuroectodermal tumor 22 | 3,035
oligodendroglioma 21 | 2,850
lung cancer 20 | 4,740
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
astrocytic glioma 17 | 2,597
lung carcinoma 17 | 2,843
Epilepsy 16 | 792
Malignant hyperthermia 16 | 26
Pick disease 16 | 1,894
Hypertension 15 | 396
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
malignant mesothelioma 15 | 3,232
subependymal giant cell astrocytoma 15 | 2,287
Autosomal recessive predisposition 14 | 1,442
Bipolar Disorder 14 | 666
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
lung adenocarcinoma 14 | 2,716
pituitary cancer 14 | 1,972
Cancer 13 | 2,499
Heart disease 13 | 306
Liver cancer 12 | 604
Schizophrenia 12 | 1,160
colon cancer 12 | 1,478
Endometrial cancer 11 | 311
diabetes mellitus 11 | 1,728
tuberculosis 11 | 2,010
Hypertensive disease 10 | 292
Intellectual disability 9 | 1,016
invasive ductal carcinoma 9 | 2,951
pancreatic cancer 9 | 2,398
Cerebrovascular disease 8 | 238
Hypertensive disorder 8 | 56
Melanoma 8 | 711
Myopathy 8 | 185
Skin cancer 8 | 469
cystic fibrosis 8 | 1,696
non-small cell lung cancer 8 | 2,890
Alzheimer's disease 7 | 658
Obesity 7 | 678
ductal carcinoma in situ 7 | 1,745
ulcerative colitis 7 | 1,819
Depressive disorder 6 | 409
Liver Cirrhosis, Experimental 6 | 769
Rheumatoid arthritis 6 | 1,191
Seizures 6 | 596
acute quadriplegic myopathy 6 | 1,158
group 4 medulloblastoma 6 | 1,855
Amenorrhea Secondary to Ovarian Dysfunction 5 | 8
Anemia 5 | 365
Angina Pectoris 5 | 32
Atopic dermatitis 5 | 952
Atrophic vaginitis 5 | 14
Autistic Disorder 5 | 364
Cardiomegaly 5 | 116
Catecholaminergic polymorphic ventricular tachycardia 5 | 12
Cognitive delay 5 | 608
Conn's syndrome 5 | 22
Contraception 5 | 15
Corpus Luteum Insufficiency Syndrome 5 | 8
Dizziness 5 | 26
Dysfunctional uterine bleeding 5 | 9
Endometrial Hyperplasia Prevention 5 | 9
Endometrial carcinoma 5 | 15
Endometriosis 5 | 540
Global developmental delay 5 | 608
Heart failure 5 | 162
Infertility Secondary to Progesterone Deficiency 5 | 8
Kidney disease 5 | 430
Male infertility 5 | 206
Menopausal flushing 5 | 17
Mental and motor retardation 5 | 608
Postmenopausal osteoporosis 5 | 19
Prevention of Premature Labor 5 | 9
Proximal muscle weakness 5 | 47
Proximal neurogenic muscle weakness 5 | 47
Secondary malignant neoplasm of kidney 5 | 9
Secondary physiologic amenorrhea 5 | 32
Syncope 5 | 22
Toxic encephalopathy 5 | 141
Type 2 diabetes mellitus 5 | 272
Ventricular arrhythmia 5 | 27
Vertigo 5 | 29
astrocytoma 5 | 1,146
cutaneous lupus erythematosus 5 | 1,057
interstitial cystitis 5 | 2,312
non primary Sjogren syndrome sicca 5 | 891
pediatric high grade glioma 5 | 1,064

Tissue

Endocrine System 78 | 18,159
Nervous System 76 | 16,725
Digestive Tract 74 | 17,369
Blood and immune system 73 | 16,909
Male tissues 73 | 17,142
Skin and soft tissues 73 | 17,230
Female tissues 71 | 17,400
Liver and Pancreas 69 | 16,750
Urinary Tract 69 | 16,678
Respiratory system 68 | 16,393
Cardiovascular System 58 | 15,192

Target Family

Ion Channel 43 | 344
Non-IDG 22 | 12,091
Enzyme 11 | 4,145
Transporter 2 | 473
Kinase 1 | 634

Compartment GO Term

Calcium channel complex 79 | 79
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2 Tbio Transporter -2.87498 737.3 295
Heat shock-related 70 kDa protein 2 HSPA2 Tbio Non-IDG -1.98655 104.3 162
Junctophilin-2 JPH2 Tbio Non-IDG -2.21890 163.0 229
Cation channel sperm-associated protein subunit zeta CATSPERZ Tdark Non-IDG 0.15 0.79 0
Potassium channel subfamily U member 1 KCNU1 Tbio Ion Channel -1.65772 43.3 45
Maltase-glucoamylase, intestinal MGAM Tclin Enzyme -4.52158 32564.4 32
Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G Tclin Ion Channel -2.16668 140.8 217
Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 Tbio Ion Channel -1.46356 25.4 471
Nucleoporin GLE1 GLE1 Tbio Non-IDG -2.24700 173.6 150
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 CD38 Tclin Enzyme -3.44680 2663.1 1493