Development Level

Tbio 60 | 11,445
Tchem 4 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 12 | 979
decreased grip strength 2 | 116
embryonic lethality prior to o... 2 | 239
increased fasted circulating g... 2 | 76
increased startle reflex 2 | 112
abnormal behavior 1 | 298
decreased bone mineral density 1 | 126
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased threshold for audito... 1 | 26
embryonic lethality prior to t... 1 | 278
hypoactivity 1 | 132
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating fructosa... 1 | 13
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased red blood cell distr... 1 | 34
increased total body fat amoun... 1 | 134
polycystic kidney 1 | 15
prenatal lethality prior to he... 1 | 87
thrombocytosis 1 | 27

Disease

Carcinoma 46 | 11,493
ovarian cancer 39 | 8,520
osteosarcoma 26 | 7,950
lung cancer 25 | 4,740
medulloblastoma, large-cell 25 | 6,241
group 3 medulloblastoma 24 | 4,104
atypical teratoid / rhabdoid tumor 20 | 5,112
glioblastoma 19 | 5,792
malignant mesothelioma 19 | 3,232
psoriasis 19 | 6,694
ependymoma 18 | 4,679
Multiple myeloma 17 | 1,332
Cancer 15 | 2,499
adult high grade glioma 14 | 3,801
oligodendroglioma 14 | 2,850
astrocytic glioma 13 | 2,597
primitive neuroectodermal tumor 13 | 3,035
Astrocytoma, Pilocytic 12 | 3,081
dermatomyositis 11 | 966
Intellectual disability 10 | 1,016
Waldenstrons macroglobulinemia 10 | 765
Dull intelligence 9 | 645
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Muscular atrophy 9 | 71
Poor school performance 9 | 645
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
Kidney cancer 8 | 2,613
acute quadriplegic myopathy 8 | 1,158
diabetes mellitus 8 | 1,728
juvenile dermatomyositis 8 | 1,187
subependymal giant cell astrocytoma 8 | 2,287
Breast cancer 7 | 3,578
Pick disease 7 | 1,894
acute myeloid leukemia 7 | 783
non primary Sjogren syndrome sicca 7 | 891
progressive supranuclear palsy 7 | 676
Cognitive delay 6 | 608
Global developmental delay 6 | 608
Mental and motor retardation 6 | 608
Neurodegenerative disease 6 | 414
Osteoporosis 6 | 363
Short stature 6 | 531
Spinal muscular atrophy 6 | 34
adrenocortical carcinoma 6 | 1,428
astrocytoma 6 | 1,146
invasive ductal carcinoma 6 | 2,951
non-small cell lung cancer 6 | 2,890
pancreatic cancer 6 | 2,398
Amyotrophic lateral sclerosis 5 | 451
Autosomal recessive predisposition 5 | 1,442
Dyskeratosis congenita 5 | 24
Fetal Growth Retardation 5 | 189
Frequent fractures 5 | 53
Increased fracture rate 5 | 53
Infant, Small for Gestational Age 5 | 176
Intrauterine retardation 5 | 176
Varying degree of multiple fractures 5 | 53
cutaneous lupus erythematosus 5 | 1,057
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
pediatric high grade glioma 5 | 1,064
spina bifida 5 | 1,074
Anemia 4 | 365
Anteverted nostril 4 | 191
Blood Coagulation Disorders 4 | 42
Cellular immunodeficiency 4 | 17
Coagulation abnormalities 4 | 27
Conductive hearing loss 4 | 123
Decreased platelet count 4 | 111
Dementia 4 | 175
Disease Models, Animal 4 | 155
Down syndrome 4 | 499
Duchenne muscular dystrophy 4 | 601
Dystrophia unguium 4 | 53
Frontotemporal dementia 4 | 51
Glaucoma 4 | 239
Hemoglobin low 4 | 124
Hemorrhagic Disorders 4 | 30
Hyperhidrosis disorder 4 | 81
Increased sweating 4 | 81
Malabsorption 4 | 82
Neutrophil abnormality 4 | 20
Photophobia 4 | 121
Recurrent respiratory infections 4 | 141
Sensorineural Hearing Loss (disorder) 4 | 284
Sparse hair 4 | 59
Sweating 4 | 81
Thin, sparse hair 4 | 59
Thrombocytopenia 4 | 197
Vascular disease 4 | 319
colon cancer 4 | 1,478
hepatocellular carcinoma 4 | 547
lung adenocarcinoma 4 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
periodontitis 4 | 293
pituitary cancer 4 | 1,972
tuberculosis 4 | 2,010
tuberculosis and treatment for 6 months 4 | 409

Tissue

Blood and immune system 65 | 16,909
Digestive Tract 65 | 17,369
Endocrine System 65 | 18,159
Female tissues 65 | 17,400
Liver and Pancreas 65 | 16,750
Male tissues 65 | 17,142
Nervous System 65 | 16,725
Respiratory system 65 | 16,393
Skin and soft tissues 65 | 17,230
Urinary Tract 65 | 16,678
Cardiovascular System 64 | 15,192

Target Family

Non-IDG 45 | 12,091
Enzyme 13 | 4,145
Epigenetic 3 | 242
Kinase 2 | 634
Transcription Factor 2 | 1,400

Compartment GO Term

Cajal body 65 | 65
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP-dependent RNA helicase DDX42 DDX42 Tbio Enzyme -1.10894 13.3 60
Adenylate kinase isoenzyme 6 AK6 Tbio Kinase -2.18859 223.1 91
Zinc finger protein 473 ZNF473 Tbio Transcription Factor -1.11630 12.6 101
Nucleolar protein 58 NOP58 Tbio Non-IDG -1.46442 30.0 85
Splicing factor U2AF 35 kDa subunit-like protein U2AF1 Tbio Non-IDG -1.71712 73.6 0
Cystathionine beta-synthase-like protein CBS Tbio Non-IDG -3.25635 3246.1 0
Trimethylguanosine synthase TGS1 Tbio Enzyme -1.40283 26.5 103
H/ACA ribonucleoprotein complex subunit 2 NHP2 Tbio Non-IDG -1.51951 28.7 54
Large subunit GTPase 1 homolog LSG1 Tbio Enzyme -1.10947 10.1 31
E3 ubiquitin-protein ligase TRIM22 TRIM22 Tbio Enzyme -1.55110 43.3 199