Development Level

Tbio 55 | 10,625
Tchem 5 | 1,890
Tdark 3 | 7,003

IMPC Phenotype

preweaning lethality, complete... 8 | 633
abnormal behavior 1 | 226
abnormal retina morphology 1 | 100
abnormal retinal blood vessel ... 1 | 18
abnormal retinal vasculature m... 1 | 15
abnormal rib morphology 1 | 28
decreased CD4-positive, CD25-p... 1 | 24
decreased KLRG1+ CD4 alpha bet... 1 | 2
decreased NK T cell number 1 | 28
decreased bone mineral density 1 | 126
decreased circulating chloride... 1 | 32
decreased circulating insulin ... 1 | 75
decreased circulating sodium l... 1 | 18
decreased gamma-delta T cell n... 1 | 18
decreased grip strength 1 | 123
decreased leukocyte cell numbe... 1 | 54
decreased lymphocyte cell numb... 1 | 9
decreased neutrophil cell numb... 1 | 37
decreased total body fat amoun... 1 | 186
decreased total retina thickne... 1 | 20
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
increased circulating HDL chol... 1 | 63
increased circulating calcium ... 1 | 32
increased circulating chloride... 1 | 43
increased circulating choleste... 1 | 53
increased circulating serum al... 1 | 25
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased fasted circulating g... 1 | 68
increased granulocyte number 1 | 8
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased mean platelet volume 1 | 19
increased total body fat amoun... 1 | 57
persistence of hyaloid vascula... 1 | 22
polycystic kidney 1 | 9
prenatal lethality prior to he... 1 | 64
thrombocytosis 1 | 23

Disease

ovarian cancer 39 | 8,491
osteosarcoma 25 | 7,933
medulloblastoma, large-cell 23 | 6,234
lung cancer 22 | 4,473
malignant mesothelioma 19 | 3,163
psoriasis 18 | 6,685
Multiple myeloma 17 | 1,327
atypical teratoid / rhabdoid tumor 16 | 4,369
glioblastoma 16 | 5,572
Cancer 14 | 2,346
ependymoma 14 | 2,514
group 3 medulloblastoma 14 | 2,254
oligodendroglioma 13 | 2,849
primitive neuroectodermal tumor 12 | 3,031
astrocytic glioma 11 | 2,241
dermatomyositis 11 | 966
pilocytic astrocytoma 11 | 3,086
Waldenstrons macroglobulinemia 10 | 764
pediatric high grade glioma 10 | 2,712
Muscular atrophy 9 | 67
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,289
Carcinoma 8 | 2,147
acute quadriplegic myopathy 8 | 1,157
adult high grade glioma 8 | 2,148
diabetes mellitus 8 | 1,663
juvenile dermatomyositis 8 | 1,189
Pick disease 7 | 1,893
acute myeloid leukemia 7 | 785
astrocytoma 7 | 1,493
progressive supranuclear palsy 7 | 674
subependymal giant cell astrocytoma 7 | 2,287
Breast cancer 6 | 3,098
Neurodegenerative disease 6 | 383
adrenocortical carcinoma 6 | 1,427
non-small cell lung cancer 6 | 2,798
pancreatic cancer 6 | 2,300
sonic hedgehog group medulloblastoma 6 | 1,482
Dyskeratosis congenita 5 | 24
cutaneous lupus erythematosus 5 | 1,056
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
invasive ductal carcinoma 5 | 2,950
non primary Sjogren syndrome sicca 5 | 840
Amyotrophic Lateral Sclerosis 4 | 432
Down syndrome 4 | 548
Duchenne muscular dystrophy 4 | 602
Spinal muscular atrophy 4 | 24
Vascular disease 4 | 281
atypical teratoid/rhabdoid tumor 4 | 1,095
colon cancer 4 | 1,475
ductal carcinoma in situ 4 | 1,745
hepatocellular carcinoma 4 | 550
lung adenocarcinoma 4 | 2,714
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
pituitary cancer 4 | 1,972
primary Sjogren syndrome 4 | 788
tuberculosis and treatment for 6 months 4 | 686
Aphasia 3 | 22
Apraxia 3 | 25
Atherosclerosis 3 | 275
Dementia 3 | 129
Frontotemporal dementia 3 | 47
Hematologic cancer 3 | 9
IGA Glomerulonephritis 3 | 454
Immune system cancer 3 | 38
Intellectual disability 3 | 573
Microcephaly 3 | 149
Retinitis pigmentosa 3 | 156
aldosterone-producing adenoma 3 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
glioblastoma multiforme 3 | 347
group 4 medulloblastoma 3 | 1,875
lung carcinoma 3 | 2,844
medulloblastoma 3 | 1,524
posterior fossa group A ependymoma 3 | 1,511
spina bifida 3 | 1,064
Alzheimer's disease 2 | 644
Anemia 2 | 252
Brain disease 2 | 84
Cardiovascular system disease 2 | 194
Dystonia 2 | 77
Endometriosis 2 | 535
HIV Infections 2 | 99
Hepatitis C 2 | 90
Homocystinuria 2 | 23
Hyperhomocysteinemia 2 | 34
Influenza 2 | 142
Multiple Sclerosis 2 | 498
Osteoporosis 2 | 259
Pityriasis versicolor 2 | 18
Tinea corporis 2 | 25
Voyeurism 2 | 4
active Crohn's disease 2 | 918
breast carcinoma 2 | 1,614
inflammatory breast cancer 2 | 404
mucosa-associated lymphoid tissue lymphoma 2 | 480
non diabetic and post-ischemic heart failure 2 | 200
pancreatic carcinoma 2 | 567
primary pancreatic ductal adenocarcinoma 2 | 1,271
tuberculosis 2 | 1,563

Tissue

Blood and immune system 62 | 17,994
Cardiovascular System 62 | 17,957
Digestive Tract 62 | 18,472
Female tissues 62 | 18,646
Liver and Pancreas 62 | 18,135
Male tissues 62 | 17,968
Nervous System 62 | 18,560
Endocrine System 60 | 18,511
Respiratory system 59 | 17,483
Skin and soft tissues 59 | 18,114
Urinary Tract 59 | 18,443

Target Family

Non-IDG 43 | 11,969
Enzyme 13 | 4,146
Epigenetic 3 | 242
Kinase 2 | 634
Transcription Factor 2 | 1,400

Compartment GO Term

Cajal body 63 | 63
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
U4/U6 small nuclear ribonucleoprotein Prp4 PRPF4 Tchem Non-IDG -0.55879 7.56 79
Protein Mis18-beta OIP5 Tbio Non-IDG -1.17135 15.6 42
Trimethylguanosine synthase TGS1 Tbio Enzyme -1.36236 24.4 85
Coilin COIL Tbio Non-IDG -2.30679 198.6 200
U4/U6 small nuclear ribonucleoprotein Prp3 PRPF3 Tbio Non-IDG -1.71435 998.6 107
U4/U6.U5 tri-snRNP-associated protein 1 SART1 Tbio Non-IDG -1.81163 66.1 137
Splicing factor U2AF 35 kDa subunit U2AF1 Tbio Non-IDG -1.65806 64.1 140
Serine/arginine-rich splicing factor 2 SRSF2 Tbio Non-IDG -2.50808 295.2 86
ELL-associated factor 1 EAF1 Tdark Non-IDG 0.09 0.79 76
Protein FRG1 FRG1 Tbio Non-IDG -1.26007 19.6 158