Development Level

Tbio 2 | 11,445

IMPC Phenotype

abnormal embryo size 1 | 220
increased bone mineral density 1 | 72
preweaning lethality, complete... 1 | 979

Disease

Acquired scoliosis 2 | 281
Anteverted nostril 2 | 191
Autosomal recessive predisposition 2 | 1,442
Bell Palsy 2 | 58
Byzanthine arch palate 2 | 194
COLD-INDUCED SWEATING SYNDROME 1 2 | 3
Chubby cheeks 2 | 50
Crisponi syndrome 2 | 2
Curvature of spine 2 | 282
Death in early childhood 2 | 82
Death in infancy 2 | 82
Decreased joint mobility 2 | 53
Facial Paresis 2 | 59
Facial muscle weakness of muscles innervated by CN VII 2 | 58
Feeding difficulties 2 | 127
Feeding difficulties in infancy 2 | 175
Flexion contracture of proximal interphalangeal joint 2 | 75
Full cheeks 2 | 50
Hyperhidrosis disorder 2 | 81
Hyperkyphosis 2 | 111
Hyperplasia of cheeks 2 | 50
Hypertrophy of cheeks 2 | 50
Hypohidrosis 2 | 34
Impaired cognition 2 | 96
Increased sweating 2 | 81
Kyphosis deformity of spine 2 | 114
Large face 2 | 7
Limited elbow extension 2 | 19
Long philtrum 2 | 137
Malignant hyperpyrexia due to anesthesia 2 | 10
Mental impairment 2 | 95
Muscle Hypertonia 2 | 88
Puffy cheeks 2 | 50
Radially deviated fingers 2 | 38
Respiratory Insufficiency 2 | 132
Respiratory function loss 2 | 121
Scoliosis 2 | 44
Sudden Cardiac Death 2 | 29
Sweating 2 | 81
Wide nose 2 | 35
cold-induced sweating syndrome 2 | 7
Acquired cubitus valgus 1 | 18
Acquired flat foot 1 | 72
Adducted thumb 1 | 22
Alexithymia 1 | 16
COLD-INDUCED SWEATING SYNDROME 2 1 | 1
Concave bridge of nose 1 | 195
Congenital Camptodactyly 1 | 40
Congenital clinodactyly 1 | 57
Congenital clubfoot 1 | 109
Curvature of digit 1 | 57
Dental caries 1 | 164
Depressed nasal bridge 1 | 195
Depressed nasal root/bridge 1 | 195
Dyspnea 1 | 76
Flatfoot 1 | 73
Flexion contracture - elbow 1 | 32
Focal segmental glomerulosclerosis 1 | 10
Foot Deformities 1 | 30
Glossopharyngeal neuralgia 1 | 5
Hematocele of tunica vaginalis testis 1 | 3
Hydrocephalus 1 | 152
Hypernasal voice 1 | 39
Hypoplastic mandible condyle 1 | 275
Intermittent fever 1 | 15
Kyphoscoliosis deformity of spine 1 | 60
Labyrinthitis 1 | 3
Low set ears 1 | 181
Lumbar lordosis 1 | 35
Mandibular hypoplasia 1 | 275
Meniere's disease 1 | 24
Micrognathism 1 | 275
Microstomia 1 | 78
Nasal voice 1 | 39
Neurilemmoma 1 | 23
Opisthotonus 1 | 14
Peripheral sensorimotor neuropathy 1 | 16
Prominent ear 1 | 56
Protruding ears 1 | 56
Retrognathia 1 | 54
Rotting teeth 1 | 73
Sensorineural hearing loss 1 | 106
Short hands 1 | 50
Short neck 1 | 140
Simple syndactyly of toes, first web space 1 | 23
Stomach carcinoma in situ 1 | 2
Tapering fingers (finding) 1 | 25
Thoracolumbar scoliosis 1 | 4
Trigeminal Neuralgia 1 | 24
adult high grade glioma 1 | 3,801
cystic fibrosis 1 | 1,696
ependymoma 1 | 4,679
fibroadenoma 1 | 559
glioblastoma 1 | 5,792
group 4 medulloblastoma 1 | 1,855
interstitial cystitis 1 | 2,312
malignant mesothelioma 1 | 3,232
non diabetic and post-ischemic heart failure 1 | 200
non-inflammatory breast cancer 1 | 66
psoriasis 1 | 6,694

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Non-IDG 2 | 12,091

Compartment GO Term

CRLF-CLCF1 complex 2 | 2
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cardiotrophin-like cytokine factor 1 CLCF1 Tbio Non-IDG -1.35883 23.2 162
Cytokine receptor-like factor 1 CRLF1 Tbio Non-IDG -2.68186 464.7 169