Development Level

Tbio 14 | 11,445
Tdark 2 | 6,588

IMPC Phenotype

decreased total body fat amoun... 2 | 207
abnormal liver morphology 1 | 17
abnormal stomach morphology 1 | 10
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased grip strength 1 | 116
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
preweaning lethality, complete... 1 | 979

Disease

ovarian cancer 14 | 8,520
Carcinoma 12 | 11,493
osteosarcoma 11 | 7,950
Kidney cancer 6 | 2,613
glioblastoma 5 | 5,792
Breast cancer 4 | 3,578
acute quadriplegic myopathy 4 | 1,158
astrocytoma 4 | 1,146
Astrocytoma, Pilocytic 3 | 3,081
Chylomicron retention disease 3 | 11
Congenital dyserythropoietic anemia 3 | 18
Short stature 3 | 531
Stomatitis 3 | 21
active Crohn's disease 3 | 922
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
lung adenocarcinoma 3 | 2,716
psoriasis 3 | 6,694
Abnormal skeletal development 2 | 60
Acquired scoliosis 2 | 281
Attention deficit hyperactivity disorder 2 | 278
Autosomal recessive predisposition 2 | 1,442
Big calvaria 2 | 147
Broad flat nasal bridge 2 | 236
Convex nasal bridge 2 | 57
Curvature of spine 2 | 282
Decreased projection of midface 2 | 105
Dental caries 2 | 164
Frontal bossing 2 | 157
Hypotrophic malar bone 2 | 129
Hypotrophic midface 2 | 105
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Late tooth eruption 2 | 61
Long philtrum 2 | 137
Malar flattening 2 | 129
Midface retrusion 2 | 105
Multiple myeloma 2 | 1,332
Muscle hypotonia 2 | 571
Nasal bridge wide 2 | 236
Orbital separation excessive 2 | 244
Osteochondrodysplasias 2 | 72
Pick disease 2 | 1,894
Prominent nasal bridge 2 | 57
Rheumatoid arthritis 2 | 1,191
Rotting teeth 2 | 73
Small midface 2 | 105
adult high grade glioma 2 | 3,801
group 4 medulloblastoma 2 | 1,855
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
juvenile dermatomyositis 2 | 1,187
non primary Sjogren syndrome sicca 2 | 891
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
posterior fossa group A ependymoma 2 | 468
Abnormality of the pharynx 1 | 19
Acne 1 | 52
Acquired flat foot 1 | 72
Acrocephaly 1 | 12
Brittle hair 1 | 25
Communicating Hydrocephalus 1 | 8
Congenital hypoplasia of kidney 1 | 32
Decreased size of teeth 1 | 62
Decreased width of tooth 1 | 59
Defective tooth enamel 1 | 31
Dentinogenesis imperfecta 1 | 25
DiGeorge syndrome 1 | 47
Diffuse large B-cell lymphoma 1 | 39
Dysseborrheic dermatitis 1 | 13
Dystrophic tooth enamel 1 | 31
Early tooth exfoliation 1 | 17
Enamel abnormalities 1 | 31
Flatfoot 1 | 73
Fractured hair 1 | 25
Fragile hair 1 | 25
Hyperkyphosis 1 | 111
Hyperpigmentation 1 | 37
Hypocalcemia 1 | 32
Hypoparathyroidism 1 | 41
Impaired T cell function 1 | 14
Joint laxity 1 | 54
Kyphosis deformity of spine 1 | 114
Microdontia (disorder) 1 | 59
Mild Mental Retardation 1 | 70
Osteogenesis imperfecta 1 | 34
Overfolded helix 1 | 24
Platyspondyly 1 | 56
Posterior Y-sutural cataract 1 | 3
Premature tooth loss 1 | 17
Reduced tensile strength of hair 1 | 25
Seborrheic dermatitis 1 | 31
Strawberry nevus of skin 1 | 10
Synostotic Posterior Plagiocephaly 1 | 8
Tetany 1 | 18
Tooth hypoplasia 1 | 7
Williams-Beuren syndrome 1 | 50

Tissue

Blood and immune system 16 | 16,909
Cardiovascular System 16 | 15,192
Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678

Target Family

Non-IDG 14 | 12,091
Enzyme 1 | 4,145
Transcription Factor 1 | 1,400

Compartment GO Term

COPII vesicle coat 16 | 16
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein transport protein Sec16A SEC16A Tbio Non-IDG -1.49890 33.9 31
Programmed cell death protein 6 PDCD6 Tbio Non-IDG -1.74455 59.1 235
Protein transport protein Sec24C SEC24C Tbio Non-IDG -0.97939 10.3 94
Transmembrane emp24 domain-containing protein 7 TMED7 Tdark Non-IDG -0.23318 2.14 18
Prolactin regulatory element-binding protein PREB Tbio Transcription Factor -2.36585 221.7 63
Protein transport protein Sec31A SEC31A Tbio Non-IDG -1.18458 13.0 88
Protein transport protein Sec24D SEC24D Tbio Non-IDG -1.08383 8.63 66
Kelch-like protein 12 KLHL12 Tbio Non-IDG -0.99873 10.5 240
Trafficking protein particle complex subunit 12 TRAPPC12 Tbio Non-IDG -0.50060 3.07 61
Peflin PEF1 Tbio Non-IDG -1.51362 30.5 127