Development Level

Tbio 31 | 11,445
Tchem 4 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
female infertility 2 | 60
male infertility 2 | 123
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal heart shape 1 | 5
abnormal liver size 1 | 5
abnormal pericardium morpholog... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal thymus morphology 1 | 7
abnormal urinary bladder morph... 1 | 11
decreased bone mineral density 1 | 126
decreased circulating serum al... 1 | 82
decreased prepulse inhibition 1 | 82
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hydrometra 1 | 53
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased body weight 1 | 25
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
preweaning lethality, incomple... 1 | 499
small seminal vesicle 1 | 10
small spleen 1 | 19
small superior vagus ganglion 1 | 74
small thymus 1 | 16

Disease

ovarian cancer 23 | 8,520
Carcinoma 17 | 11,493
osteosarcoma 17 | 7,950
atypical teratoid / rhabdoid tumor 15 | 5,112
lung cancer 14 | 4,740
Cancer 13 | 2,499
glioblastoma 12 | 5,792
medulloblastoma, large-cell 12 | 6,241
Multiple myeloma 11 | 1,332
adult high grade glioma 10 | 3,801
ependymoma 10 | 4,679
psoriasis 10 | 6,694
Waldenstrons macroglobulinemia 9 | 765
malignant mesothelioma 8 | 3,232
primitive neuroectodermal tumor 8 | 3,035
Astrocytoma, Pilocytic 7 | 3,081
group 3 medulloblastoma 7 | 4,104
Breast cancer 6 | 3,578
astrocytic glioma 6 | 2,597
group 4 medulloblastoma 6 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
Parkinson's disease 5 | 392
medulloblastoma 5 | 720
oligodendroglioma 5 | 2,850
Schizophrenia 4 | 1,160
Stevens-Johnson syndrome 4 | 92
acute quadriplegic myopathy 4 | 1,158
tuberculosis 4 | 2,010
Alzheimer's disease 3 | 658
Asthma 3 | 385
Carcinoma, Hepatocellular 3 | 228
Cockayne syndrome 3 | 60
Liver carcinoma 3 | 240
Melanoma 3 | 711
Pick disease 3 | 1,894
Rheumatoid arthritis 3 | 1,191
Stomach Neoplasms 3 | 300
acute myeloid leukemia 3 | 783
colon cancer 3 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
invasive ductal carcinoma 3 | 2,951
lung carcinoma 3 | 2,843
non-small cell lung cancer 3 | 2,890
subependymal giant cell astrocytoma 3 | 2,287
Disease Progression 2 | 136
Hemangiosarcoma 2 | 18
Hypertension 2 | 396
Hypertensive disease 2 | 292
Obesity 2 | 678
Xeroderma pigmentosum 2 | 43
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
diabetes mellitus 2 | 1,728
fibroadenoma 2 | 559
gastric cancer 2 | 459
hepatocellular carcinoma 2 | 547
hereditary spastic paraplegia 2 | 318
interstitial cystitis 2 | 2,312
juvenile dermatomyositis 2 | 1,187
nasopharyngeal carcinoma 2 | 1,058
non primary Sjogren syndrome sicca 2 | 891
pancreatic cancer 2 | 2,398
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
posterior fossa group B ependymoma 2 | 416
primary pancreatic ductal adenocarcinoma 2 | 1,109
spina bifida 2 | 1,074
tuberculosis and treatment for 6 months 2 | 409
ulcerative colitis 2 | 1,819
Adenocarcinoma of lung 1 | 142
Adult T-Cell Lymphoma/Leukemia 1 | 30
Alcoholic Intoxication, Chronic 1 | 289
Amyotrophic lateral sclerosis 1 | 451
Breast Neoplasms 1 | 445
Cataract 7 1 | 32
Colonic Neoplasms 1 | 142
Disease Models, Animal 1 | 155
HIV Infections 1 | 102
Leukemia-Lymphoma, Adult T-Cell 1 | 30
Liver disease 1 | 237
Liver diseases 1 | 87
Liver neoplasms 1 | 130
Lung Neoplasms 1 | 232
Mammary Neoplasms 1 | 425
Narcolepsy 1 | 72
Neoplasm Invasiveness 1 | 161
Neurodevelopmental Disorders 1 | 70
Pseudohypoaldosteronism 1 | 23
REM sleep behavior disorder 1 | 14
Scabies 1 | 7
Skin cancer 1 | 469
Status Epilepticus 1 | 98
Systemic lupus erythematosus 1 | 194
Toxic encephalopathy 1 | 141
Yellow fever 1 | 16
atypical teratoid/rhabdoid tumor 1 | 357
cystic fibrosis and chronic rhinosinusitis 1 | 214
sarcoidosis 1 | 370

Tissue

Blood and immune system 37 | 16,909
Cardiovascular System 37 | 15,192
Digestive Tract 37 | 17,369
Endocrine System 37 | 18,159
Female tissues 37 | 17,400
Liver and Pancreas 37 | 16,750
Male tissues 37 | 17,142
Nervous System 37 | 16,725
Respiratory system 37 | 16,393
Skin and soft tissues 37 | 17,230
Urinary Tract 37 | 16,678

Target Family

Non-IDG 27 | 12,091
Enzyme 8 | 4,145
Kinase 1 | 634
Transcription Factor 1 | 1,400

Compartment GO Term

COP9 signalosome 37 | 37
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,237 | 12,237
Intracellular organelle 12,023 | 12,023
membrane-bounded organelle 11,130 | 11,130
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,340 | 10,340
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,561 | 7,561
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,972 | 3,972
non-membrane-bounded organelle 3,972 | 3,972
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,955 | 1,955
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,547 | 1,547
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,123 | 1,123
Nuclear outer membrane-endopla... 1,121 | 1,121
Nucleoplasm part 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,040 | 1,040
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 949 | 949
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 848 | 848
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Linker for activation of T-cells family member 1 LAT Tbio Non-IDG -2.16291 169.4 667
Ubiquitin carboxyl-terminal hydrolase 15 USP15 Tbio Enzyme -1.64742 41.6 242
IQ domain-containing protein H IQCH Tdark Non-IDG -0.06695 2.00 23
COP9 signalosome complex subunit 4 COPS4 Tbio Non-IDG -0.91181 7.39 88
COP9 signalosome complex subunit 9 COPS9 Tbio Non-IDG 0.21 0.92 14
DET1- and DDB1-associated protein 1 DDA1 Tbio Non-IDG -0.93875 9.33 125
26S proteasome non-ATPase regulatory subunit 14 PSMD14 Tbio Enzyme -1.80255 64.2 195
COP9 signalosome complex subunit 7a COPS7A Tbio Non-IDG -1.50943 32.2 154
DNA damage-binding protein 1 DDB1 Tbio Non-IDG -2.34719 202.5 353
COP9 signalosome complex subunit 1 GPS1 Tbio Non-IDG -1.62973 42.8 246