Development Level

Tbio 8 | 11,445

IMPC Phenotype

preweaning lethality, complete... 2 | 979
decreased bone mineral density 1 | 126

Disease

ovarian cancer 7 | 8,520
Carcinoma 6 | 11,493
lung cancer 5 | 4,740
psoriasis 5 | 6,694
Breast cancer 4 | 3,578
ependymoma 4 | 4,679
invasive ductal carcinoma 4 | 2,951
Astrocytoma, Pilocytic 3 | 3,081
Kidney cancer 3 | 2,613
atypical teratoid / rhabdoid tumor 3 | 5,112
glioblastoma 3 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
malignant mesothelioma 3 | 3,232
medulloblastoma, large-cell 3 | 6,241
osteosarcoma 3 | 7,950
Amyotrophic lateral sclerosis 2 | 451
Autosomal recessive predisposition 2 | 1,442
Cancer 2 | 2,499
Cataract 2 | 297
Dull intelligence 2 | 645
Endometriosis 2 | 540
Epilepsy 2 | 792
Failure to gain weight 2 | 365
Intellectual disability 2 | 1,016
Lens Opacities 2 | 231
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Multiple Sclerosis 2 | 540
Multiple myeloma 2 | 1,332
Muscle hypotonia 2 | 571
Pediatric failure to thrive 2 | 365
Poor school performance 2 | 645
Rheumatoid arthritis 2 | 1,191
Seizures 2 | 596
Short stature 2 | 531
Small head 2 | 374
Sparse hair 2 | 59
Strabismus 2 | 270
Thin, sparse hair 2 | 59
acute quadriplegic myopathy 2 | 1,158
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
group 3 medulloblastoma 2 | 4,104
group 4 medulloblastoma 2 | 1,855
lung adenocarcinoma 2 | 2,716
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
primary pancreatic ductal adenocarcinoma 2 | 1,109
primitive neuroectodermal tumor 2 | 3,035
ulcerative colitis 2 | 1,819
ALDH18A1-related De Barsy syndrome 1 | 1
Abnormal upper motor neuron morphology 1 | 11
Abnormality of pelvic girdle bone morphology 1 | 37
Adducted thumb 1 | 22
Adenocarcinoma of lung 1 | 142
Autosomal dominant cutis laxa 1 | 3
Brisk reflexes 1 | 3
Broad cranium shape 1 | 88
Broad forehead 1 | 59
Bulging forehead 1 | 66
CUTIS LAXA, AUTOSOMAL DOMINANT 3 1 | 1
CUTIS LAXA, AUTOSOMAL RECESSIVE, TYPE IIIA 1 | 1
Cardiovascular system disease 1 | 246
Carpal bone hypoplasia 1 | 6
Congenital Bilateral Cataracts 1 | 50
Disease Models, Animal 1 | 155
Distortion of face 1 | 46
Funny looking face 1 | 46
Hiatal Hernia 1 | 7
Isolated cases 1 | 72
Joint hyperflexibility 1 | 78
Large bregma sutures 1 | 46
Large dysplastic ears 1 | 87
Large pinnae 1 | 87
Large prominent ears 1 | 87
Large, floppy ears 1 | 87
Large, late-closing fontanelle 1 | 46
Narrow nasal ridge 1 | 6
Neurogenic muscle atrophy, especially in the lower limbs 1 | 139
Prominent forehead 1 | 66
Prominent superficial vasculature 1 | 3
Protruding ears 1 | 56
Range of joint movement increased 1 | 32
Retinitis pigmentosa 11 1 | 59
SPASTIC PARAPLEGIA 9B, AUTOSOMAL RECESSIVE 1 | 1
Small wrist bones 1 | 6
Spastic paraplegia 9 1 | 1
Spastic paraplegia 9, autosomal dominant 1 | 1
Specific learning disability 1 | 47
Weakness of lower limb 1 | 27
Wide bregma sutures 1 | 46
Wide skull shape 1 | 88

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Non-IDG 4 | 12,091
Enzyme 3 | 4,145
Transcription Factor 1 | 1,400

Compartment GO Term

CBF3 complex 8 | 8
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Delta-1-pyrroline-5-carboxylate synthase ALDH18A1 Tbio Enzyme -2.34260 216.5 146
CCAAT/enhancer-binding protein zeta CEBPZ Tbio Non-IDG -1.84043 65.8 126
Cdc42 effector protein 3 CDC42EP3 Tbio Non-IDG -1.57638 37.5 124
Histone H3-like centromeric protein A CENPA Tbio Non-IDG -2.73322 567.0 386
S-phase kinase-associated protein 1 SKP1 Tbio Enzyme -2.57150 310.1 381
Alpha-aminoadipic semialdehyde synthase, mitochondrial AASS Tbio Enzyme -1.48335 30.6 128
Little elongation complex subunit 1 ICE1 Tbio Non-IDG -1.58677 39.4 17
Recombining binding protein suppressor of hairless RBPJ Tbio Transcription Factor -2.67790 444.5 266