Development Level

Tbio 45 | 11,445
Tchem 21 | 1,598
Tclin 8 | 613
Tdark 3 | 6,588

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal lens morphology 2 | 81
cataract 2 | 92
decreased body length 2 | 101
decreased leukocyte cell numbe... 2 | 73
impaired glucose tolerance 2 | 75
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
preweaning lethality, incomple... 2 | 499
prolonged ST segment 2 | 36
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal incisor color 1 | 3
abnormal iris morphology 1 | 13
abnormal kidney morphology 1 | 65
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal spine curvature 1 | 9
abnormal spleen morphology 1 | 55
abnormal urinary bladder morph... 1 | 11
abnormal vocalization 1 | 21
absent pinna reflex 1 | 23
cardiovascular system phenotyp... 1 | 36
cystolithiasis 1 | 3
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged kidney 1 | 14
enlarged spleen 1 | 41
enlarged urinary bladder 1 | 8
eyelids fail to open 1 | 3
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased circulating amylase ... 1 | 25
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased grip strength 1 | 41
increased kidney weight 1 | 6
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
kyphosis 1 | 5
polycystic kidney 1 | 15
prolonged QT interval 1 | 38
small kidney 1 | 16

Disease

Carcinoma 59 | 11,493
osteosarcoma 31 | 7,950
psoriasis 31 | 6,694
Autosomal recessive predisposition 25 | 1,442
ovarian cancer 25 | 8,520
lung cancer 22 | 4,740
medulloblastoma, large-cell 19 | 6,241
non-small cell lung cancer 18 | 2,890
glioblastoma 17 | 5,792
ulcerative colitis 17 | 1,819
Kidney disease 15 | 430
active Crohn's disease 15 | 922
diabetes mellitus 15 | 1,728
lung adenocarcinoma 15 | 2,716
lung carcinoma 15 | 2,843
malignant mesothelioma 15 | 3,232
Diarrhea 14 | 253
atypical teratoid / rhabdoid tumor 14 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
nephrosclerosis 14 | 333
Kidney cancer 13 | 2,613
ependymoma 13 | 4,679
Obesity 12 | 678
colon cancer 12 | 1,478
Cancer 11 | 2,499
Metabolic acidosis 11 | 90
cystic fibrosis 11 | 1,696
Anemia 10 | 365
Breast cancer 10 | 3,578
Hypertension 10 | 396
adult high grade glioma 10 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
invasive ductal carcinoma 10 | 2,951
tuberculosis 10 | 2,010
Hypophosphatemia 9 | 40
Nephrolithiasis 9 | 56
pancreatic cancer 9 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
Failure to gain weight 8 | 365
Pediatric failure to thrive 8 | 365
active ulcerative colitis 8 | 764
ductal carcinoma in situ 8 | 1,745
interstitial cystitis 8 | 2,312
oligodendroglioma 8 | 2,850
Atherosclerosis 7 | 291
Epilepsy 7 | 792
Schizophrenia 7 | 1,160
adrenocortical carcinoma 7 | 1,428
group 3 medulloblastoma 7 | 4,104
pediatric high grade glioma 7 | 1,064
Astrocytoma, Pilocytic 6 | 3,081
Calcinosis 6 | 70
Cognitive delay 6 | 608
Coronary artery disease 6 | 268
Diabetes mellitus type 2 6 | 69
Global developmental delay 6 | 608
Gout 6 | 106
Hartnup disease 6 | 13
Hyperglycemia 6 | 137
Hyperphosphatemia 6 | 32
Hypertensive disease 6 | 292
Hypoglycemia 6 | 152
Mental and motor retardation 6 | 608
Osteomalacia 6 | 35
Osteoporosis 6 | 363
Rickets 6 | 49
astrocytic glioma 6 | 2,597
breast carcinoma 6 | 1,638
facioscapulohumeral dystrophy 6 | 288
group 4 medulloblastoma 6 | 1,855
pituitary cancer 6 | 1,972
primitive neuroectodermal tumor 6 | 3,035
Cystinuria 5 | 18
Heart disease 5 | 306
Hypercalcemia 5 | 59
Hyperuricemia 5 | 49
Intellectual disability 5 | 1,016
Liver Cirrhosis, Experimental 5 | 769
Liver cancer 5 | 604
Liver disease 5 | 237
Melanoma 5 | 711
Muscle hypotonia 5 | 571
Seizures 5 | 596
Skin cancer 5 | 469
Alzheimer's disease 4 | 658
Bipolar Disorder 4 | 666
Dementia 4 | 175
Depressive disorder 4 | 409
Highly variable severity 4 | 157
Kidney Failure 4 | 111
Large intestine cancer 4 | 126
Pick disease 4 | 1,894
Prostatic Neoplasms 4 | 495
Proteinuria 4 | 144
Renal Insufficiency 4 | 90
Variable expressivity 4 | 157
astrocytoma 4 | 1,146
cutaneous lupus erythematosus 4 | 1,057
subependymal giant cell astrocytoma 4 | 2,287

Tissue

Digestive Tract 75 | 17,369
Urinary Tract 72 | 16,678
Skin and soft tissues 71 | 17,230
Endocrine System 70 | 18,159
Male tissues 70 | 17,142
Liver and Pancreas 69 | 16,750
Female tissues 66 | 17,400
Nervous System 65 | 16,725
Blood and immune system 63 | 16,909
Respiratory system 59 | 16,393
Cardiovascular System 45 | 15,192

Target Family

Transporter 38 | 473
Non-IDG 22 | 12,091
Enzyme 15 | 4,145
GPCR 1 | 408
Ion Channel 1 | 344

Compartment GO Term

Brush border membrane 77 | 77
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-1,4-galactosyltransferase 1 B4GALT1 Tbio Enzyme -2.34454 211.1 130
Sodium-dependent phosphate transport protein 1 SLC17A1 Tbio Transporter -1.73498 53.1 39
Aquaporin-1 AQP1 Tbio Non-IDG -3.08125 1107.4 374
Niemann-Pick C1-like protein 1 NPC1L1 Tclin Non-IDG -2.33312 222.7 139
Major facilitator superfamily domain-containing protein 10 MFSD10 Tbio Non-IDG -2.17526 146.3 66
Multidrug and toxin extrusion protein 2 SLC47A2 Tchem Transporter -1.71307 47.1 133
Proton-coupled folate transporter SLC46A1 Tchem Transporter -2.23182 177.1 76
V-type proton ATPase 116 kDa subunit a isoform 4 ATP6V0A4 Tbio Enzyme -2.84949 692.2 90
Aminopeptidase N ANPEP Tchem Enzyme -3.28127 1843.4 1222
Maltase-glucoamylase, intestinal MGAM Tclin Enzyme -4.52158 32564.4 32