Development Level

Tbio 76 | 11,651
Tchem 23 | 1,388
Tclin 17 | 612
Tdark 3 | 6,593

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 6 | 979
absent pinna reflex 3 | 23
increased circulating HDL chol... 3 | 80
increased circulating sodium l... 3 | 71
preweaning lethality, incomple... 3 | 499
prolonged ST segment 3 | 36
abnormal embryo size 2 | 220
abnormal lens morphology 2 | 81
cataract 2 | 92
decreased body length 2 | 101
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased circulating triglyce... 2 | 79
decreased grip strength 2 | 116
decreased leukocyte cell numbe... 2 | 73
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased circulating alkaline... 2 | 122
increased circulating chloride... 2 | 41
increased mean corpuscular hem... 2 | 96
prolonged QT interval 2 | 38
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal heart morphology 1 | 162
abnormal incisor color 1 | 3
abnormal iris morphology 1 | 13
abnormal kidney morphology 1 | 65
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal spine curvature 1 | 9
abnormal spleen morphology 1 | 55
abnormal urinary bladder morph... 1 | 11
abnormal vibrissa morphology 1 | 25
abnormal vocalization 1 | 21
cardiovascular system phenotyp... 1 | 36
cystolithiasis 1 | 3
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating potassiu... 1 | 20
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
enlarged kidney 1 | 14
enlarged spleen 1 | 41
enlarged urinary bladder 1 | 8
eyelids fail to open 1 | 3
hydrometra 1 | 53
hypoactivity 1 | 132
impaired righting response 1 | 26
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating total pr... 1 | 28
increased grip strength 1 | 41
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
kyphosis 1 | 5
limb grasping 1 | 41
polycystic kidney 1 | 15
prolonged PR interval 1 | 15
small kidney 1 | 16
small superior vagus ganglion 1 | 74
stereotypic behavior 1 | 3
trunk curl 1 | 16

Disease

Carcinoma 92 | 11,493
psoriasis 52 | 6,694
osteosarcoma 46 | 7,950
ovarian cancer 42 | 8,520
Autosomal recessive predisposition 35 | 1,442
diabetes mellitus 34 | 1,728
lung cancer 34 | 4,740
intraductal papillary-mucinous carcinoma (IPMC) 32 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 29 | 2,955
ulcerative colitis 28 | 1,819
Cancer 27 | 2,499
glioblastoma 27 | 5,792
Kidney cancer 25 | 2,613
Kidney disease 25 | 430
lung adenocarcinoma 25 | 2,716
malignant mesothelioma 25 | 3,232
medulloblastoma, large-cell 25 | 6,241
Hypertension 24 | 396
lung carcinoma 24 | 2,843
pancreatic cancer 23 | 2,398
Diarrhea 22 | 253
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
non-small cell lung cancer 22 | 2,890
Breast cancer 21 | 3,578
atypical teratoid / rhabdoid tumor 21 | 5,112
ependymoma 21 | 4,679
Obesity 20 | 678
Anemia 19 | 365
cystic fibrosis 19 | 1,696
colon cancer 18 | 1,478
nephrosclerosis 18 | 333
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,962
Schizophrenia 16 | 1,160
active Crohn's disease 16 | 922
adult high grade glioma 15 | 3,801
invasive ductal carcinoma 15 | 2,951
tuberculosis 15 | 2,010
Metabolic acidosis 14 | 90
group 3 medulloblastoma 14 | 4,104
interstitial cystitis 14 | 2,312
oligodendroglioma 14 | 2,850
pituitary cancer 14 | 1,972
Astrocytoma, Pilocytic 13 | 3,081
Atherosclerosis 13 | 291
ductal carcinoma in situ 13 | 1,745
Coronary artery disease 12 | 268
Epilepsy 12 | 792
Heart disease 12 | 306
breast carcinoma 12 | 1,638
pediatric high grade glioma 12 | 1,064
primitive neuroectodermal tumor 12 | 3,035
subependymal giant cell astrocytoma 12 | 2,287
Alzheimer's disease 11 | 658
Failure to gain weight 11 | 365
Liver Cirrhosis, Experimental 11 | 769
Liver disease 11 | 237
Osteoporosis 11 | 363
Pediatric failure to thrive 11 | 365
astrocytic glioma 11 | 2,597
Hyperglycemia 10 | 137
Hypertensive disease 10 | 292
Liver cancer 10 | 604
active ulcerative colitis 10 | 764
adrenocortical carcinoma 10 | 1,428
Cerebrovascular disease 9 | 238
Fatty liver disease 9 | 103
Heart failure 9 | 162
Hyperuricemia 9 | 47
Hypoglycemia 9 | 152
Hypophosphatemia 9 | 40
Melanoma 9 | 711
Nephrolithiasis 9 | 56
Prostatic Neoplasms 9 | 495
Cholestasis 8 | 155
Cognitive delay 8 | 608
Diabetes mellitus type 2 8 | 69
Global developmental delay 8 | 608
Hyperphosphatemia 8 | 32
Intellectual disability 8 | 1,016
Mental and motor retardation 8 | 608
Pancreatitis 8 | 123
Rheumatoid arthritis 8 | 1,191
Skin cancer 8 | 469
facioscapulohumeral dystrophy 8 | 288
group 4 medulloblastoma 8 | 1,855
Alcohol dependence 7 | 107
Bipolar Disorder 7 | 666
Gout 7 | 104
Hepatomegaly 7 | 285
Hyperparathyroidism 7 | 48
Kidney Diseases 7 | 114
Muscle hypotonia 7 | 571
Myopathy 7 | 185
Osteomalacia 7 | 35
Pick disease 7 | 1,894
Proteinuria 7 | 144
Rickets 7 | 49
Toxic encephalopathy 7 | 141
acute quadriplegic myopathy 7 | 1,158
primary pancreatic ductal adenocarcinoma 7 | 1,109

Tissue

Digestive Tract 114 | 17,369
Urinary Tract 110 | 16,678
Skin and soft tissues 108 | 17,230
Endocrine System 107 | 18,159
Liver and Pancreas 106 | 16,750
Male tissues 106 | 17,142
Female tissues 104 | 17,400
Nervous System 101 | 16,725
Blood and immune system 99 | 16,909
Respiratory system 95 | 16,393
Cardiovascular System 77 | 15,192

Target Family

Non-IDG 46 | 12,091
Transporter 38 | 473
Enzyme 30 | 4,145
Ion Channel 3 | 344
GPCR 1 | 408
Kinase 1 | 634

Compartment GO Term

Brush border 119 | 119
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alkaline phosphatase, placental type ALPP Tbio Enzyme -2.71952 511.2 929
Unconventional myosin-VIIb MYO7B Tbio Non-IDG -0.65885 5.07 14
Intelectin-1 ITLN1 Tbio Non-IDG -2.49500 337.0 194
Gastric intrinsic factor GIF Tbio Non-IDG -3.20615 1559.4 172
Platelet glycoprotein 4 CD36 Tbio Non-IDG -2.63884 376.0 1155
Ezrin EZR Tbio Non-IDG -2.99865 981.3 1088
Unconventional myosin-Vb MYO5B Tbio Non-IDG -1.96052 93.4 42
Unconventional myosin-Id MYO1D Tbio Non-IDG -1.39704 23.1 63
Trehalase TREH Tchem Enzyme -2.14508 137.4 51
Glutamyl aminopeptidase ENPEP Tchem Enzyme -2.81719 655.7 311