Development Level

Tbio 94 | 10,625
Tchem 32 | 1,890
Tclin 20 | 602
Tdark 7 | 7,003

Collection

Eligible Ion Channel Proteins 2 | 117

IMPC Term

decreased bone mineral content 9 | 157
decreased bone mineral density 8 | 126
preweaning lethality, complete... 8 | 633
decreased lean body mass 7 | 195
abnormal behavior 6 | 226
abnormal bone structure 5 | 131
decreased grip strength 5 | 123
increased circulating alkaline... 5 | 119
decreased total body fat amoun... 4 | 186
hypoactivity 4 | 89
decreased body weight 3 | 174
decreased startle reflex 3 | 48
embryonic lethality prior to t... 3 | 187
increased blood urea nitrogen ... 3 | 44
increased bone mineral density 3 | 52
increased circulating creatini... 3 | 29
increased circulating total pr... 3 | 20
increased mean corpuscular vol... 3 | 91
tremors 3 | 34
abnormal bone mineralization 2 | 55
abnormal gait 2 | 51
abnormal retinal pigmentation 2 | 61
abnormal sleep behavior 2 | 63
abnormal startle reflex 2 | 14
decreased circulating insulin ... 2 | 75
decreased circulating triglyce... 2 | 83
decreased effector memory CD8-... 2 | 24
decreased fasted circulating g... 2 | 49
decreased leukocyte cell numbe... 2 | 54
decreased prepulse inhibition 2 | 52
enlarged heart 2 | 111
hyperactivity 2 | 108
improved glucose tolerance 2 | 56
increased B cell number 2 | 23
increased circulating chloride... 2 | 43
increased circulating phosphat... 2 | 24
increased circulating potassiu... 2 | 31
increased circulating serum al... 2 | 25
increased eosinophil cell numb... 2 | 9
increased grip strength 2 | 83
increased mean corpuscular hem... 2 | 93
increased rib number 2 | 41
short tibia 2 | 82
thrombocytopenia 2 | 46
abnormal QRS complex 1 | 25
abnormal ear morphology 1 | 5
abnormal epididymis morphology 1 | 31
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 51
abnormal kidney morphology 1 | 30
abnormal lens morphology 1 | 73
abnormal pelvic girdle bone mo... 1 | 11
abnormal retina morphology 1 | 100
abnormal rib morphology 1 | 28
abnormal skin morphology 1 | 23
abnormal tail movements 1 | 12
abnormal thoracic vertebrae mo... 1 | 16
corneal opacity 1 | 25
decreased NK T cell number 1 | 28
decreased body length 1 | 108
decreased caudal vertebrae num... 1 | 49
decreased circulating chloride... 1 | 32
decreased eosinophil cell numb... 1 | 41
decreased exploration in new e... 1 | 9
decreased heart weight 1 | 44
decreased hemoglobin content 1 | 53
decreased mean corpuscular vol... 1 | 50
decreased neutrophil cell numb... 1 | 37
decreased rib number 1 | 59
decreased spleen weight 1 | 13
embryonic lethality prior to o... 1 | 148
enlarged heart atrium 1 | 2
impaired glucose tolerance 1 | 52
increased NK T cell number 1 | 11
increased bone mineral content 1 | 92
increased caudal vertebrae num... 1 | 8
increased circulating HDL chol... 1 | 63
increased circulating alanine ... 1 | 11
increased circulating aspartat... 1 | 17
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating fructosa... 1 | 11
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 24
increased exploration in new e... 1 | 56
increased gamma-delta T cell n... 1 | 16
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
lethargy 1 | 5
limb grasping 1 | 35
long tibia 1 | 13
prenatal lethality prior to he... 1 | 64
shortened PQ interval 1 | 6
small seminal vesicle 1 | 6
vertebral fusion 1 | 23

Disease

osteosarcoma 77 | 7,933
psoriasis 75 | 6,685
ovarian cancer 74 | 8,484
medulloblastoma, large-cell 63 | 6,234
lung cancer 58 | 4,466
glioblastoma 53 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 51 | 3,289
non-small cell lung cancer 48 | 2,798
intraductal papillary-mucinous adenoma (IPMA) 45 | 2,956
lung carcinoma 44 | 2,844
Breast cancer 43 | 3,094
atypical teratoid / rhabdoid tumor 43 | 4,369
intraductal papillary-mucinous carcinoma (IPMC) 42 | 2,988
malignant mesothelioma 42 | 3,162
Cancer 41 | 2,346
pancreatic cancer 41 | 2,300
invasive ductal carcinoma 40 | 2,950
lung adenocarcinoma 40 | 2,713
Carcinoma 38 | 2,147
pilocytic astrocytoma 38 | 3,086
pituitary cancer 38 | 1,972
subependymal giant cell astrocytoma 34 | 2,287
oligodendroglioma 33 | 2,849
pediatric high grade glioma 33 | 2,712
ductal carcinoma in situ 31 | 1,745
interstitial cystitis 30 | 2,299
primitive neuroectodermal tumor 30 | 3,031
cystic fibrosis 29 | 1,665
ependymoma 28 | 2,514
atypical teratoid/rhabdoid tumor 27 | 1,095
astrocytic glioma 26 | 2,241
ulcerative colitis 26 | 2,087
breast carcinoma 24 | 1,614
tuberculosis 24 | 1,557
group 4 medulloblastoma 22 | 1,875
primary pancreatic ductal adenocarcinoma 22 | 1,271
adult high grade glioma 21 | 2,148
gastric carcinoma 21 | 832
Pick disease 20 | 1,893
colon cancer 20 | 1,475
posterior fossa group B ependymoma 20 | 1,530
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,795
sonic hedgehog group medulloblastoma 18 | 1,482
cutaneous lupus erythematosus 16 | 1,056
esophageal adenocarcinoma 16 | 737
posterior fossa group A ependymoma 16 | 1,511
Kidney disease 15 | 396
diabetes mellitus 15 | 1,663
group 3 medulloblastoma 15 | 2,254
nasopharyngeal carcinoma 15 | 1,056
spina bifida 15 | 1,064
Down syndrome 14 | 548
Obesity 14 | 616
Rheumatoid Arthritis 14 | 1,160
fibroadenoma 14 | 557
nephrosclerosis 14 | 329
active Crohn's disease 13 | 918
medulloblastoma 13 | 1,524
Endometriosis 12 | 535
acute quadriplegic myopathy 12 | 1,157
adrenocortical carcinoma 12 | 1,427
primary Sjogren syndrome 11 | 789
Epilepsy 10 | 346
Mammary Neoplasms 10 | 410
Prostatic Neoplasms 10 | 471
Schizophrenia 10 | 501
chronic rhinosinusitis 10 | 512
mucosa-associated lymphoid tissue lymphoma 10 | 480
pancreatic carcinoma 10 | 567
progressive supranuclear palsy 10 | 674
Alzheimer's disease 9 | 644
Anemia 9 | 252
Animal Mammary Neoplasms 9 | 136
Autistic Disorder 9 | 320
Duchenne muscular dystrophy 9 | 602
Heart disease 9 | 279
Hypertension 9 | 287
Liver disease 9 | 219
Peripheral Neuropathy 9 | 303
Sensorineural hearing loss 9 | 107
Vascular disease 9 | 281
active ulcerative colitis 9 | 477
Amyotrophic Lateral Sclerosis 8 | 431
Atopic dermatitis 8 | 944
Colonic Neoplasms 8 | 126
Colorectal Neoplasms 8 | 217
Diarrhea 8 | 155
Intellectual disability 8 | 573
Lung Neoplasms 8 | 171
Mammary Neoplasms, Experimental 8 | 150
Metabolic acidosis 8 | 49
Multiple Sclerosis 8 | 498
Osteoporosis 8 | 257
acute myeloid leukemia 8 | 780
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 499
dermatomyositis 8 | 933
ovarian neoplasm 8 | 97
sarcoidosis 8 | 358
Asthma 7 | 349
juvenile dermatomyositis 7 | 1,189

Tissue

Digestive Tract 149 | 18,473
Female tissues 149 | 18,647
Nervous System 149 | 18,561
Urinary Tract 149 | 18,444
Endocrine System 148 | 18,512
Liver and Pancreas 148 | 18,136
Blood and immune system 147 | 17,995
Male tissues 147 | 17,969
Cardiovascular System 146 | 17,958
Skin and soft tissues 146 | 18,115
Respiratory system 145 | 17,484

Target Family

Non-IDG 86 | 11,971
Transporter 33 | 473
Ion Channel 14 | 341
Kinase 8 | 634
Enzyme 7 | 4,146
GPCR 5 | 406

Compartment GO Term

Basolateral plasma membrane 153 | 153
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium/hydrogen exchanger 4 SLC9A4 Tdark Transporter -1.25841 17.4 6
Sodium/calcium exchanger 2 SLC8A2 Tbio Transporter -1.56223 31.9 51
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.92762 876.7 339
Zinc transporter ZIP5 SLC39A5 Tbio Transporter -1.03936 12.4 60
Serotransferrin TF Tchem Non-IDG -4.13136 13124.3 952
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.39868 2437.0 1167
Band 3 anion transport protein SLC4A1 Tbio Transporter -3.02453 1271.7 133
Solute carrier family 22 member 6 SLC22A6 Tclin Transporter -2.27998 196.4 186
Lactoperoxidase LPO Tbio Enzyme -2.69742 442.5 160
Leptin receptor LEPR Tclin Non-IDG -2.98449 751.7 530