Development Level

Tbio 100 | 11,178
Tchem 34 | 1,885
Tclin 20 | 612
Tdark 9 | 6,569

Collection

Ion Channel: IDG Consortium (T... 2 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 12 | 979
abnormal behavior 7 | 298
decreased bone mineral content 6 | 151
abnormal bone structure 5 | 187
decreased grip strength 5 | 116
embryonic lethality prior to t... 5 | 278
increased circulating HDL chol... 5 | 80
increased mean corpuscular vol... 5 | 92
abnormal embryo size 4 | 220
abnormal pericardium morpholog... 4 | 26
decreased startle reflex 4 | 75
decreased total body fat amoun... 4 | 207
abnormal retina morphology 3 | 71
abnormal sleep behavior 3 | 70
decreased body length 3 | 101
decreased body weight 3 | 161
decreased bone mineral density 3 | 126
decreased lean body mass 3 | 135
decreased prepulse inhibition 3 | 82
enlarged heart 3 | 210
hypoactivity 3 | 132
increased circulating alkaline... 3 | 122
increased circulating choleste... 3 | 66
increased circulating creatini... 3 | 38
increased circulating total pr... 3 | 28
increased lean body mass 3 | 172
tremors 3 | 39
abnormal bone mineralization 2 | 38
abnormal eye morphology 2 | 68
abnormal heart morphology 2 | 162
abnormal limb bud morphology 2 | 17
abnormal neural tube closure 2 | 46
abnormal startle reflex 2 | 15
decreased circulating insulin ... 2 | 76
decreased circulating triglyce... 2 | 79
decreased exploration in new e... 2 | 11
decreased fasted circulating g... 2 | 65
decreased leukocyte cell numbe... 2 | 73
decreased vertical activity 2 | 208
embryonic growth retardation 2 | 106
hyperactivity 2 | 148
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased blood urea nitrogen ... 2 | 48
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased circulating calcium ... 2 | 34
increased circulating chloride... 2 | 41
increased circulating iron lev... 2 | 30
increased circulating potassiu... 2 | 29
increased circulating serum al... 2 | 22
increased circulating sodium l... 2 | 71
increased mean corpuscular hem... 2 | 96
increased mean platelet volume 2 | 45
increased or absent threshold ... 2 | 101
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
pale yolk sac 2 | 25
pallor 2 | 34
prenatal lethality prior to he... 2 | 87
preweaning lethality, incomple... 2 | 499
thrombocytopenia 2 | 56
abnormal blood vessel morpholo... 1 | 5
abnormal craniofacial morpholo... 1 | 33
abnormal ear morphology 1 | 9
abnormal embryo turning 1 | 31
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal locomotor behavior 1 | 24
abnormal neural tube morpholog... 1 | 12
abnormal seminal vesicle morph... 1 | 114
abnormal tail movements 1 | 12
absent vibrissae 1 | 12
cardiovascular system phenotyp... 1 | 36
corneal opacity 1 | 32
decreased circulating chloride... 1 | 30
decreased circulating sodium l... 1 | 22
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased heart rate variabili... 1 | 13
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 31
embryonic lethality prior to o... 1 | 239
impaired righting response 1 | 26
increased anti-nuclear antigen... 1 | 19
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating fructosa... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating phosphat... 1 | 26
increased circulating triglyce... 1 | 42
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased monocyte cell number 1 | 63
limb grasping 1 | 41
long tibia 1 | 25
shortened RR interval 1 | 17
small testis 1 | 58
trunk curl 1 | 16

Disease

Carcinoma 121 | 11,192
ovarian cancer 81 | 8,297
osteosarcoma 80 | 7,766
psoriasis 75 | 6,514
lung cancer 63 | 4,607
glioblastoma 60 | 5,635
medulloblastoma, large-cell 60 | 6,086
ependymoma 59 | 4,559
atypical teratoid / rhabdoid tumor 58 | 4,971
intraductal papillary-mucinous neoplasm (IPMN) 52 | 3,204
Breast cancer 50 | 3,469
malignant mesothelioma 48 | 3,135
non-small cell lung cancer 47 | 2,799
Cancer 46 | 2,388
intraductal papillary-mucinous adenoma (IPMA) 46 | 2,872
pancreatic cancer 46 | 2,322
lung carcinoma 45 | 2,755
adult high grade glioma 44 | 3,701
intraductal papillary-mucinous carcinoma (IPMC) 44 | 2,902
Kidney cancer 43 | 2,548
lung adenocarcinoma 43 | 2,627
invasive ductal carcinoma 42 | 2,867
Astrocytoma, Pilocytic 40 | 3,006
group 3 medulloblastoma 38 | 4,002
pituitary cancer 37 | 1,915
Autosomal recessive predisposition 36 | 1,407
subependymal giant cell astrocytoma 35 | 2,230
ductal carcinoma in situ 34 | 1,686
interstitial cystitis 33 | 2,237
oligodendroglioma 33 | 2,768
cystic fibrosis 30 | 1,629
primitive neuroectodermal tumor 29 | 2,957
astrocytic glioma 28 | 2,530
tuberculosis 26 | 1,963
breast carcinoma 25 | 1,589
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,911
primary pancreatic ductal adenocarcinoma 23 | 1,071
colon cancer 22 | 1,428
gastric carcinoma 21 | 781
Schizophrenia 20 | 1,136
ulcerative colitis 20 | 1,765
active Crohn's disease 19 | 882
active ulcerative colitis 19 | 736
spina bifida 18 | 1,053
Intellectual disability 17 | 998
Pick disease 17 | 1,856
cutaneous lupus erythematosus 16 | 1,016
diabetes mellitus 16 | 1,683
group 4 medulloblastoma 16 | 1,806
Dull intelligence 15 | 634
Epilepsy 15 | 775
Low intelligence 15 | 634
Mental Retardation 15 | 634
Mental deficiency 15 | 634
Poor school performance 15 | 634
Rheumatoid arthritis 15 | 1,156
fibroadenoma 15 | 538
nasopharyngeal carcinoma 15 | 1,024
Down syndrome 14 | 480
Liver cancer 14 | 589
esophageal adenocarcinoma 14 | 696
Hypertension 13 | 372
Kidney disease 13 | 411
Liver Cirrhosis, Experimental 13 | 733
Melanoma 13 | 689
nephrosclerosis 13 | 314
Lung Neoplasms 12 | 217
acute quadriplegic myopathy 12 | 1,133
mucosa-associated lymphoid tissue lymphoma 12 | 473
Endometriosis 11 | 521
Hypertensive disease 11 | 278
Liver disease 11 | 227
Obesity 11 | 655
Osteoporosis 11 | 348
Prostatic Neoplasms 11 | 472
Skin cancer 11 | 451
adrenocortical carcinoma 11 | 1,385
atypical teratoid/rhabdoid tumor 11 | 349
primary Sjogren syndrome 11 | 710
Alzheimer's disease 10 | 640
Autistic Disorder 10 | 358
Bipolar Disorder 10 | 646
Breast Neoplasms 10 | 423
Cholestasis 10 | 154
Diarrhea 10 | 245
Mammary Neoplasms 10 | 403
Mammary Neoplasms, Animal 10 | 130
Muscle hypotonia 10 | 562
chronic rhinosinusitis 10 | 505
pediatric high grade glioma 10 | 1,035
Atopic dermatitis 9 | 915
Disease Models, Animal 9 | 148
Kidney Failure 9 | 108
Multiple Sclerosis 9 | 527
Neoplasm Metastasis 9 | 160
Seizures 9 | 584
aldosterone-producing adenoma 9 | 646
pancreatic carcinoma 9 | 555
progressive supranuclear palsy 9 | 656
sarcoidosis 9 | 357

Tissue

Digestive Tract 157 | 17,369
Endocrine System 156 | 18,159
Female tissues 154 | 17,400
Nervous System 154 | 16,725
Urinary Tract 154 | 16,678
Liver and Pancreas 153 | 16,750
Male tissues 153 | 17,142
Skin and soft tissues 150 | 17,230
Blood and immune system 147 | 16,909
Respiratory system 141 | 16,393
Cardiovascular System 138 | 15,192

Target Family

Non-IDG 93 | 12,091
Transporter 36 | 473
Ion Channel 13 | 344
Kinase 8 | 634
Enzyme 7 | 4,145
GPCR 6 | 408

Compartment GO Term

Basolateral plasma membrane 163 | 163
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Prominin-2 PROM2 Tbio Non-IDG -1.12562 11.0 199
Solute carrier family 22 member 8 SLC22A8 Tclin Transporter -2.40126 258.4 113
Copper-transporting ATPase 1 ATP7A Tbio Enzyme -3.08069 1155.0 263
Receptor tyrosine-protein kinase erbB-4 ERBB4 Tclin Kinase -2.78704 558.2 1072
Aquaporin-5 AQP5 Tbio Non-IDG -2.65367 454.1 197
Anion exchange transporter SLC26A7 Tbio Transporter -1.26445 19.4 41
Aquaporin-4 AQP4 Tchem Non-IDG -3.33435 2159.1 358
Monocarboxylate transporter 10 SLC16A10 Tbio Transporter -1.31424 19.2 74
Potassium voltage-gated channel subfamily KQT member 4 KCNQ4 Tclin Ion Channel -2.04030 109.2 258
Multidrug resistance-associated protein 6 ABCC6 Tchem Transporter -2.71911 547.1 100