Development Level

Tbio 8 | 11,445

IMPC Phenotype

abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased circulating triglyce... 1 | 42
increased large unstained cell... 1 | 5
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
persistence of hyaloid vascula... 1 | 33

Disease

Carcinoma 8 | 11,493
Astrocytoma, Pilocytic 7 | 3,081
interstitial cystitis 7 | 2,312
lung cancer 7 | 4,740
ovarian cancer 7 | 8,520
Alport syndrome 6 | 21
Breast cancer 6 | 3,578
Kidney disease 6 | 430
atypical teratoid / rhabdoid tumor 6 | 5,112
psoriasis 6 | 6,694
Kidney cancer 5 | 2,613
Nephrotic Syndrome 5 | 78
adult high grade glioma 5 | 3,801
cystic fibrosis 5 | 1,696
ependymoma 5 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
malignant mesothelioma 5 | 3,232
medulloblastoma, large-cell 5 | 6,241
nasopharyngeal carcinoma 5 | 1,058
pituitary cancer 5 | 1,972
adrenocortical carcinoma 4 | 1,428
glioblastoma 4 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung adenocarcinoma 4 | 2,716
pancreatic cancer 4 | 2,398
ulcerative colitis 4 | 1,819
urothelial carcinoma 4 | 318
Anterior lenticonus 3 | 3
Becker muscular dystrophy 3 | 191
Chronic kidney disease stage 5 3 | 31
Congenital deafness 3 | 185
Corneal erosion 3 | 16
Deafness 3 | 198
Diffuse lamellation of the glomerular basement membrane 3 | 3
Duchenne muscular dystrophy 3 | 601
Hearing Loss, Partial 3 | 185
Hematuria 3 | 36
Hydrolethalus syndrome 3 | 128
Hypertensive disease 3 | 292
Increase in blood pressure 3 | 119
Myopia 3 | 176
Nephritis 3 | 51
Posterior polymorphous corneal dystrophy 3 | 19
Progressive disorder 3 | 142
Proteinuria 3 | 144
Sensorineural hearing loss 3 | 106
Skin cancer 3 | 469
Thickening of glomerular basement membrane 3 | 7
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
breast carcinoma 3 | 1,638
dermatomyositis 3 | 966
ductal carcinoma in situ 3 | 1,745
gastric carcinoma 3 | 807
hearing impairment 3 | 199
invasive ductal carcinoma 3 | 2,951
non-small cell lung cancer 3 | 2,890
periodontitis 3 | 293
primitive neuroectodermal tumor 3 | 3,035
pterygium 3 | 76
subependymal giant cell astrocytoma 3 | 2,287
Alport Syndrome, Autosomal Dominant 2 | 2
Alport Syndrome, Autosomal Recessive 2 | 2
Alport syndrome, dominant type 2 | 2
Autosomal recessive predisposition 2 | 1,442
Cerebral Hemorrhage 2 | 42
Cognitive delay 2 | 608
Epilepsy 2 | 792
Goodpasture syndrome 2 | 6
Hematuria, Benign Familial 2 | 2
Highly variable severity 2 | 157
Keratoconus 2 | 113
Leiomyoma 2 | 32
Leiomyomatosis 2 | 6
Lens Opacities 2 | 231
Liver Cirrhosis, Experimental 2 | 769
Liver cancer 2 | 604
Melanoma 2 | 711
Mental and motor retardation 2 | 608
Muscle Spasticity 2 | 195
Pick disease 2 | 1,894
Porencephaly 2 | 20
Seizures 2 | 596
Sensorineural Hearing Loss (disorder) 2 | 284
Variable expressivity 2 | 157
active Crohn's disease 2 | 922
acute quadriplegic myopathy 2 | 1,158
colon cancer 2 | 1,478
cutaneous lupus erythematosus 2 | 1,057
fibroadenoma 2 | 559
glioblastoma multiforme 2 | 142
group 3 medulloblastoma 2 | 4,104
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
juvenile dermatomyositis 2 | 1,187
lung carcinoma 2 | 2,843
nail-patella syndrome 2 | 16
oligodendroglioma 2 | 2,850
osteosarcoma 2 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primary pancreatic ductal adenocarcinoma 2 | 1,109

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Non-IDG 8 | 12,091

Compartment GO Term

Basement membrane collagen tri... 8 | 8
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Collagen alpha-1(XV) chain COL15A1 Tbio Non-IDG -1.18716 15.5 74
Collagen alpha-1(IV) chain COL4A1 Tbio Non-IDG -2.28595 186.9 391
Collagen alpha-1(VIII) chain COL8A1 Tbio Non-IDG -1.31054 16.6 116
Collagen alpha-6(IV) chain COL4A6 Tbio Non-IDG -1.45656 27.4 119
Collagen alpha-4(IV) chain COL4A4 Tbio Non-IDG -1.92846 80.8 41
Collagen alpha-3(IV) chain COL4A3 Tbio Non-IDG -2.32017 204.4 209
Collagen alpha-2(IV) chain COL4A2 Tbio Non-IDG -1.89339 76.6 139
Collagen alpha-5(IV) chain COL4A5 Tbio Non-IDG -2.44387 275.7 90