Development Level

Tbio 130 | 11,445
Tchem 32 | 1,598
Tclin 13 | 613
Tdark 6 | 6,588

IMPC Phenotype

preweaning lethality, complete... 9 | 979
preweaning lethality, incomple... 7 | 499
abnormal coat-hair pigmentatio... 5 | 64
abnormal behavior 4 | 298
abnormal embryo size 4 | 220
cataract 4 | 92
decreased body weight 4 | 161
decreased vertical activity 4 | 208
enlarged heart 4 | 210
abnormal heart morphology 3 | 162
abnormal lens morphology 3 | 81
decreased mean corpuscular hem... 3 | 50
decreased mean corpuscular vol... 3 | 79
decreased total body fat amoun... 3 | 207
impaired glucose tolerance 3 | 75
increased circulating triglyce... 3 | 42
abnormal femur morphology 2 | 14
abnormal humerus morphology 2 | 11
abnormal retina morphology 2 | 71
abnormal skin morphology 2 | 50
abnormal tooth morphology 2 | 24
decreased bone mineral content 2 | 151
decreased circulating bilirubi... 2 | 19
decreased circulating insulin ... 2 | 76
decreased erythrocyte cell num... 2 | 62
decreased heart weight 2 | 27
decreased lean body mass 2 | 135
embryonic lethality prior to t... 2 | 278
impaired pupillary reflex 2 | 26
increased heart weight 2 | 62
increased large unstained cell... 2 | 5
increased red blood cell distr... 2 | 34
increased startle reflex 2 | 112
mammalian phenotype 2 | 17
persistence of hyaloid vascula... 2 | 33
abnormal behavioral response t... 1 | 66
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal head size 1 | 6
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal pelvic girdle bone mo... 1 | 12
abnormal placenta size 1 | 20
abnormal retinal blood vessel ... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal tibia morphology 1 | 14
absent startle reflex 1 | 24
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 31
decreased red blood cell distr... 1 | 41
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased mean platelet volume 1 | 45
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
limb grasping 1 | 41
male infertility 1 | 123
narrow eye opening 1 | 12
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
small testis 1 | 58
syndactyly 1 | 23
tremors 1 | 39

Disease

Carcinoma 142 | 11,493
Cancer 101 | 2,499
ovarian cancer 99 | 8,520
psoriasis 96 | 6,694
glioblastoma 94 | 5,792
Breast cancer 84 | 3,578
malignant mesothelioma 84 | 3,232
ependymoma 80 | 4,679
atypical teratoid / rhabdoid tumor 74 | 5,112
lung cancer 73 | 4,740
pancreatic cancer 73 | 2,398
osteosarcoma 72 | 7,950
Astrocytoma, Pilocytic 71 | 3,081
invasive ductal carcinoma 70 | 2,951
cystic fibrosis 65 | 1,696
Kidney cancer 64 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 64 | 3,291
lung carcinoma 64 | 2,843
Kidney disease 62 | 430
diabetes mellitus 61 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 60 | 2,955
interstitial cystitis 59 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 59 | 2,989
non-small cell lung cancer 59 | 2,890
ulcerative colitis 56 | 1,819
lung adenocarcinoma 55 | 2,716
Autosomal recessive predisposition 53 | 1,442
medulloblastoma, large-cell 52 | 6,241
adult high grade glioma 50 | 3,801
ductal carcinoma in situ 45 | 1,745
breast carcinoma 44 | 1,638
primary pancreatic ductal adenocarcinoma 43 | 1,109
Heart disease 41 | 306
pituitary cancer 41 | 1,972
Liver Cirrhosis, Experimental 40 | 769
Hypertension 38 | 396
Atherosclerosis 37 | 291
gastric carcinoma 37 | 807
Duchenne muscular dystrophy 36 | 601
oligodendroglioma 36 | 2,850
subependymal giant cell astrocytoma 36 | 2,287
pancreatic ductal adenocarcinoma liver metastasis 35 | 1,962
tuberculosis 35 | 2,010
Cerebrovascular disease 34 | 238
primitive neuroectodermal tumor 34 | 3,035
Liver disease 32 | 237
adrenocortical carcinoma 32 | 1,428
colon cancer 32 | 1,478
nasopharyngeal carcinoma 32 | 1,058
Coronary artery disease 31 | 268
Liver cancer 31 | 604
Neoplasm Invasiveness 31 | 161
astrocytic glioma 31 | 2,597
Arthritis 30 | 290
Melanoma 30 | 711
Rheumatoid arthritis 30 | 1,191
Schizophrenia 30 | 1,160
autosomal dominant Emery-Dreifuss muscular dystrophy 30 | 510
group 3 medulloblastoma 30 | 4,104
Anemia 28 | 365
Obesity 28 | 678
cutaneous lupus erythematosus 28 | 1,057
Hypersensitivity reaction type II disease 27 | 253
Lung disease 27 | 142
esophageal adenocarcinoma 27 | 737
juvenile dermatomyositis 27 | 1,187
Endometriosis 26 | 540
Hypertensive disease 26 | 292
Neoplasm Metastasis 26 | 168
Osteoporosis 26 | 363
Skin cancer 26 | 469
group 4 medulloblastoma 26 | 1,855
Breast Neoplasms 25 | 445
Prostatic Neoplasms 25 | 495
Vascular disease 25 | 319
pediatric high grade glioma 25 | 1,064
Atopic dermatitis 24 | 952
Mammary Neoplasms 24 | 425
Alzheimer's disease 23 | 658
periodontitis 23 | 293
Asthma 22 | 385
Intellectual disability 22 | 1,016
Liver Cirrhosis 22 | 181
Multiple Sclerosis 22 | 540
Neuropathy 22 | 261
Becker muscular dystrophy 21 | 191
Down syndrome 21 | 499
Inflammatory bowel disease 21 | 151
Myopia 21 | 176
Stomach Neoplasms 21 | 300
dermatomyositis 21 | 966
Bipolar Disorder 20 | 666
Diabetic retinopathy 20 | 56
Myopathy 20 | 185
Pulmonary Fibrosis 20 | 106
acute quadriplegic myopathy 20 | 1,158
limb girdle muscular dystrophy 2A 20 | 213
Cataract 19 | 297
Muscle hypotonia 18 | 571
active ulcerative colitis 18 | 764

Tissue

Endocrine System 176 | 18,159
Digestive Tract 174 | 17,369
Female tissues 171 | 17,400
Urinary Tract 171 | 16,678
Skin and soft tissues 170 | 17,230
Blood and immune system 169 | 16,909
Male tissues 169 | 17,142
Nervous System 169 | 16,725
Liver and Pancreas 167 | 16,750
Respiratory system 165 | 16,393
Cardiovascular System 156 | 15,192

Target Family

Non-IDG 136 | 12,091
Enzyme 31 | 4,145
Kinase 8 | 634
Transcription Factor 5 | 1,400
Ion Channel 1 | 344

Compartment GO Term

Basement membrane 181 | 181
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Extracellular matrix protein FRAS1 FRAS1 Tbio Non-IDG -1.51346 36.5 22
EGF-containing fibulin-like extracellular matrix protein 2 EFEMP2 Tbio Non-IDG -1.67314 52.3 243
Collagen alpha-1(XV) chain COL15A1 Tbio Non-IDG -1.18716 15.5 74
Collagen alpha-1(XVIII) chain COL18A1 Tbio Non-IDG -3.18339 1561.4 433
Serum albumin ALB Tchem Non-IDG -5.01233 98804.9 2101
Alpha-fetoprotein AFP Tbio Non-IDG -4.06931 11800.5 2246
Prolyl 3-hydroxylase 2 P3H2 Tbio Enzyme -2.49306 295.2 60
Collagen alpha-1(IV) chain COL4A1 Tbio Non-IDG -2.28595 186.9 391
Beta-nerve growth factor NGF Tchem Non-IDG -4.01592 10936.7 735
Hematopoietic progenitor cell antigen CD34 CD34 Tbio Non-IDG -4.14691 13698.4 1952