Development Level

Tbio 12 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal cornea morphology 1 | 31
abnormal eye pigmentation 1 | 3
absent pinna reflex 1 | 23
corneal opacity 1 | 32
corneal vascularization 1 | 6
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased lean body mass 1 | 135
female infertility 1 | 60
increased thermal nociceptive ... 1 | 9
male infertility 1 | 123

Disease

Carcinoma 13 | 11,493
osteosarcoma 10 | 7,950
ovarian cancer 10 | 8,520
Cancer 8 | 2,499
group 3 medulloblastoma 8 | 4,104
lung cancer 7 | 4,740
Ataxia telangiectasia 6 | 34
Breast cancer 6 | 3,578
glioblastoma 6 | 5,792
malignant mesothelioma 6 | 3,232
medulloblastoma, large-cell 6 | 6,241
Hereditary Breast and Ovarian Cancer Syndrome 5 | 14
Nijmegen breakage syndrome 5 | 24
atypical teratoid / rhabdoid tumor 5 | 5,112
colon cancer 5 | 1,478
ependymoma 5 | 4,679
primitive neuroectodermal tumor 5 | 3,035
psoriasis 5 | 6,694
Breast Neoplasms 4 | 445
Intellectual disability 4 | 1,016
Kidney cancer 4 | 2,613
Mammary Neoplasms 4 | 425
astrocytic glioma 4 | 2,597
lung carcinoma 4 | 2,843
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
Autosomal recessive predisposition 3 | 1,442
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1 3 | 13
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2 3 | 8
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 3 | 9
Breast Cancer, Familial 3 | 8
Chromosome Breakage 3 | 36
Cowden disease 3 | 18
Dull intelligence 3 | 645
Fanconi anemia 3 | 56
Hereditary breast ovarian cancer 3 | 6
Li-Fraumeni syndrome 3 | 13
Liver cancer 3 | 604
Low intelligence 3 | 645
Malignant neoplasm of breast 3 | 15
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Microcephaly 3 | 166
Pick disease 3 | 1,894
Poor school performance 3 | 645
Short stature 3 | 531
Small head 3 | 374
Tumor Predisposition Syndrome 3 | 6
adrenocortical carcinoma 3 | 1,428
adult high grade glioma 3 | 3,801
ductal carcinoma in situ 3 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
subependymal giant cell astrocytoma 3 | 2,287
Acquired scoliosis 2 | 281
Almond-shaped eyes 2 | 23
Alzheimer's disease 2 | 658
Anemia 2 | 365
Bloom syndrome 2 | 29
Cognitive delay 2 | 608
Curvature of spine 2 | 282
Decreased platelet count 2 | 111
Fanconi Anemia, Complementation Group a 2 | 9
Global developmental delay 2 | 608
Increased chromosomal breakage 2 | 27
Irregular hyperpigmentation 2 | 33
Leukopenia 2 | 72
Lobular neoplasia 2 | 15
Lynch syndrome 2 | 35
Mental and motor retardation 2 | 608
Ovarian Neoplasms 2 | 102
Pancreatic Neoplasm 2 | 85
Pancreatic Neoplasms 2 | 85
Pancreatic carcinoma, familial 2 | 8
Premature Menopause 2 | 31
Prostate cancer 2 | 175
Prostate cancer, familial 2 | 13
Prostatic Neoplasms 2 | 495
Pyridoxine-responsive sideroblastic anemia 2 | 17
Radial aplasia/hypoplasia 2 | 29
Schizophrenia 2 | 1,160
Seckel syndrome 2 | 34
Short palpebral fissure 2 | 38
Thrombocytopenia 2 | 197
Waldenstrons macroglobulinemia 2 | 765
Xeroderma pigmentosum 2 | 43
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
dermatomyositis 2 | 966
group 4 medulloblastoma 2 | 1,855
hypopigmented skin patch 2 | 59
non-small cell lung carcinoma 2 | 317
ovarian neoplasm 2 | 99
progressive supranuclear palsy 2 | 676
Abdominal Pain 1 | 98
Leukemia, Lymphocytic, Chronic, B-Cell 1 | 34
Nausea and vomiting 1 | 97
Somatic mutation 1 | 61

Tissue

Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678

Target Family

Non-IDG 10 | 12,091
Enzyme 2 | 4,145
Epigenetic 1 | 242

Compartment GO Term

BRCA1-C complex 13 | 13
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
TP53-binding protein 1 TP53BP1 Tbio Epigenetic -2.69485 464.8 577
Breast cancer type 2 susceptibility protein BRCA2 Tbio Non-IDG -3.46139 2647.6 209
Microcephalin MCPH1 Tbio Non-IDG -1.96863 109.3 260
DNA topoisomerase 2-binding protein 1 TOPBP1 Tbio Enzyme -2.04312 118.0 230
Breast cancer type 1 susceptibility protein BRCA1 Tchem Non-IDG -3.76784 6081.3 1542
DNA repair protein XRCC2 XRCC2 Tbio Non-IDG -2.76304 492.9 270
BRCA1-associated RING domain protein 1 BARD1 Tbio Non-IDG -2.09264 120.7 236
PAX-interacting protein 1 PAXIP1 Tbio Non-IDG -1.63612 44.7 79
Double-strand break repair protein MRE11 MRE11 Tbio Non-IDG -2.02762 98.5 459
EGF-like repeat and discoidin I-like domain-containing protein 3 EDIL3 Tbio Non-IDG -2.05224 110.5 188