Development Level

Tbio 15 | 11,445
Tdark 4 | 6,588

IMPC Phenotype

hemorrhage 2 | 23
preweaning lethality, complete... 2 | 979
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal iris pigmentation 1 | 4
abnormal limb bud morphology 1 | 17
abnormal motor capabilities-co... 1 | 5
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
convulsive seizures 1 | 13
decreased total retina thickne... 1 | 17
edema 1 | 59
embryonic lethality prior to t... 1 | 278
increased body length 1 | 32
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
pale liver 1 | 6
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
small superior vagus ganglion 1 | 74

Disease

Hermansky-Pudlak syndrome 13 | 42
Carcinoma 9 | 11,493
Platelet storage pool deficiency 9 | 21
ovarian cancer 9 | 8,520
osteosarcoma 8 | 7,950
Oculocutaneous albinism 7 | 29
medulloblastoma, large-cell 7 | 6,241
Schizophrenia 6 | 1,160
glioblastoma 6 | 5,792
Hermanski-Pudlak Syndrome 5 | 8
atypical teratoid / rhabdoid tumor 5 | 5,112
ependymoma 5 | 4,679
malignant mesothelioma 5 | 3,232
Albinism with hemorrhagic diathesis and pigmented reticuloendothelial cells 4 | 7
Astrocytoma, Pilocytic 4 | 3,081
adult high grade glioma 4 | 3,801
group 4 medulloblastoma 4 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
oligodendroglioma 4 | 2,850
primitive neuroectodermal tumor 4 | 3,035
psoriasis 4 | 6,694
Autosomal recessive predisposition 3 | 1,442
Chediak-Higashi syndrome 3 | 26
Hermansky-Pudlak Syndrome 1 3 | 6
Nystagmus 3 | 317
Pick disease 3 | 1,894
acute quadriplegic myopathy 3 | 1,158
astrocytic glioma 3 | 2,597
juvenile dermatomyositis 3 | 1,187
pancreatic cancer 3 | 2,398
Achromasia 2 | 11
Albinism 2 | 11
Breast cancer 2 | 3,578
Congenital nystagmus 2 | 26
Crohn's disease 2 | 321
Freckles 2 | 33
Kidney cancer 2 | 2,613
Melanoma 2 | 711
Mental Depression 2 | 333
Ocular albinism 2 | 26
Piebaldism 2 | 15
Pigmentary iris degeneration 2 | 20
Pulmonary Fibrosis 2 | 106
Red hair 2 | 6
Retinal depigmentation 2 | 12
Skin cancer 2 | 469
Strabismus 2 | 270
cutaneous lupus erythematosus 2 | 1,057
diabetes mellitus 2 | 1,728
group 3 medulloblastoma 2 | 4,104
invasive ductal carcinoma 2 | 2,951
lung carcinoma 2 | 2,843
non-small cell lung cancer 2 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
subependymal giant cell astrocytoma 2 | 2,287
Albinism, Oculocutaneous, Type 2 1 | 2
Alcoholic Intoxication, Chronic 1 | 289
Angelman syndrome 1 | 34
Anterior ischemic optic neuropathy 1 | 3
Atherosclerosis 1 | 291
Duane-radial ray syndrome 1 | 8
Epilepsy 1 | 792
Frontotemporal dementia 1 | 51
HERMANSKY-PUDLAK SYNDROME 9 1 | 1
Hypopigmentation disorder 1 | 25
Liver Cirrhosis, Experimental 1 | 769
Low Vision 1 | 174
Lung Neoplasms 1 | 232
Major Depressive Disorder 1 | 301
Mood Disorders 1 | 184
Multiple Sclerosis 1 | 540
Oculocutaneous albinism type 2 1 | 2
Optic nerve abnormalities 1 | 5
Parkinson's disease 1 | 392
Photodysphoria 1 | 121
Photophobia 1 | 121
Pigment dispersion syndrome 1 | 11
Polycystic ovary syndrome 1 | 360
Prader-Willi syndrome 1 | 48
Pulmonary embolism 1 | 55
Schizoaffective Disorder 1 | 55
Systemic lupus erythematosus 1 | 194
Thrombophlebitis 1 | 19
Unipolar Depression 1 | 250
Visual Impairment 1 | 174
Vitiligo 1 | 73
Waldenstrons macroglobulinemia 1 | 765
astrocytoma 1 | 1,146
atypical teratoid/rhabdoid tumor 1 | 357
cystic fibrosis 1 | 1,696
head and neck cancer 1 | 271
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
hepatocellular carcinoma 1 | 547
medulloblastoma 1 | 720
nasopharyngeal carcinoma 1 | 1,058
pancreatic carcinoma 1 | 562
sarcoidosis 1 | 370
tuberculosis 1 | 2,010

Tissue

Blood and immune system 19 | 16,909
Digestive Tract 19 | 17,369
Endocrine System 19 | 18,159
Female tissues 19 | 17,400
Male tissues 19 | 17,142
Nervous System 19 | 16,725
Respiratory system 19 | 16,393
Skin and soft tissues 19 | 17,230
Urinary Tract 19 | 16,678
Cardiovascular System 18 | 15,192
Liver and Pancreas 18 | 16,750

Target Family

Non-IDG 17 | 12,091
Enzyme 2 | 4,145

Compartment GO Term

BLOC-1 complex 19 | 19
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

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