Development Level

Tbio 77 | 11,445
Tchem 73 | 1,598
Tclin 28 | 613
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 12 | 979
decreased vertical activity 5 | 208
embryonic lethality prior to t... 5 | 278
preweaning lethality, incomple... 5 | 499
hyperactivity 4 | 148
increased hemoglobin content 4 | 45
increased mean corpuscular hem... 4 | 96
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
abnormal spleen morphology 3 | 55
decreased bone mineral content 3 | 151
decreased circulating insulin ... 3 | 76
decreased mean corpuscular vol... 3 | 79
enlarged heart 3 | 210
enlarged spleen 3 | 41
increased total body fat amoun... 3 | 134
male infertility 3 | 123
small superior vagus ganglion 3 | 74
abnormal lens morphology 2 | 81
abnormal neural tube closure 2 | 46
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
abnormal skin morphology 2 | 50
abnormal testis morphology 2 | 43
cataract 2 | 92
decreased lean body mass 2 | 135
decreased leukocyte cell numbe... 2 | 73
decreased total body fat amoun... 2 | 207
embryonic lethality prior to o... 2 | 239
female infertility 2 | 60
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
increased hematocrit 2 | 46
increased lymphocyte cell numb... 2 | 32
increased mean corpuscular hem... 2 | 36
increased startle reflex 2 | 112
limb grasping 2 | 41
short tibia 2 | 97
small testis 2 | 58
thrombocytopenia 2 | 56
abnormal coat-hair pigmentatio... 1 | 64
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal hindbrain development 1 | 16
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal retinal inner nuclear... 1 | 8
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal startle reflex 1 | 15
abnormal vertebrae morphology 1 | 18
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating creatini... 1 | 39
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased heart left ventricle... 1 | 28
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
decreased total retina thickne... 1 | 17
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
enlarged heart atrium 1 | 4
increased body length 1 | 32
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating alkaline... 1 | 122
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased eosinophil cell numb... 1 | 11
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased large unstained cell... 1 | 5
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
microphthalmia 1 | 26
shortened RR interval 1 | 17
thin ventricular wall 1 | 24
urinary bladder obstruction 1 | 4

Disease

Cancer 165 | 2,499
ovarian cancer 113 | 8,520
Carcinoma 104 | 11,493
psoriasis 102 | 6,694
osteosarcoma 99 | 7,950
lung cancer 98 | 4,740
glioblastoma 90 | 5,792
malignant mesothelioma 71 | 3,232
diabetes mellitus 69 | 1,728
medulloblastoma, large-cell 69 | 6,241
atypical teratoid / rhabdoid tumor 66 | 5,112
Vascular disease 62 | 319
Breast cancer 61 | 3,578
Breast Neoplasms 60 | 445
Mammary Neoplasms 59 | 425
ependymoma 57 | 4,679
Prostatic Neoplasms 51 | 495
adult high grade glioma 51 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 51 | 3,291
Schizophrenia 50 | 1,160
ulcerative colitis 50 | 1,819
tuberculosis 49 | 2,010
Alzheimer's disease 48 | 658
Kidney disease 48 | 430
lung adenocarcinoma 47 | 2,716
non-small cell lung cancer 47 | 2,890
pancreatic cancer 46 | 2,398
Astrocytoma, Pilocytic 45 | 3,081
Obesity 44 | 678
Rheumatoid arthritis 44 | 1,191
invasive ductal carcinoma 44 | 2,951
lung carcinoma 44 | 2,843
Anemia 43 | 365
Stomach Neoplasms 41 | 300
group 3 medulloblastoma 41 | 4,104
Heart disease 40 | 306
interstitial cystitis 40 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 40 | 2,989
primitive neuroectodermal tumor 40 | 3,035
intraductal papillary-mucinous adenoma (IPMA) 39 | 2,955
Carcinoma, Hepatocellular 37 | 228
Liver carcinoma 37 | 240
Arthritis 36 | 290
oligodendroglioma 36 | 2,850
adrenocortical carcinoma 35 | 1,428
breast carcinoma 35 | 1,638
subependymal giant cell astrocytoma 35 | 2,287
Bipolar Disorder 34 | 666
Lung Neoplasms 34 | 232
Toxic encephalopathy 34 | 141
Hypersensitivity reaction type II disease 33 | 253
Kidney cancer 33 | 2,613
Multiple Sclerosis 33 | 540
pituitary cancer 33 | 1,972
Asthma 32 | 385
Hypertension 32 | 396
Liver Cirrhosis, Experimental 32 | 769
colon cancer 32 | 1,478
cystic fibrosis 32 | 1,696
ductal carcinoma in situ 32 | 1,745
Depressive disorder 31 | 409
group 4 medulloblastoma 31 | 1,855
Autosomal recessive predisposition 30 | 1,442
astrocytic glioma 30 | 2,597
Colonic Neoplasms 29 | 142
Endometriosis 29 | 540
Inflammatory bowel disease 29 | 151
Neoplasm Metastasis 29 | 168
Liver disease 28 | 237
Lung disease 28 | 142
Major Depressive Disorder 28 | 301
acute quadriplegic myopathy 28 | 1,158
cutaneous lupus erythematosus 28 | 1,057
pancreatic ductal adenocarcinoma liver metastasis 28 | 1,962
Adenocarcinoma 27 | 122
Mental Depression 27 | 333
Multiple myeloma 27 | 1,332
Neurodegenerative disease 27 | 414
Parkinson's disease 27 | 392
Reperfusion Injury 27 | 86
astrocytoma 27 | 1,146
Adenoma 26 | 167
Atherosclerosis 26 | 291
Brain Ischemia 26 | 110
Diarrhea 26 | 253
Melanoma 26 | 711
Pancreatic Neoplasm 26 | 85
Pancreatic Neoplasms 26 | 85
Diabetes Mellitus, Experimental 25 | 108
Hypertensive disease 25 | 292
Cell Transformation, Neoplastic 24 | 97
Cerebrovascular disease 24 | 238
Hyperglycemia 24 | 137
Myocardial Infarction 24 | 151
Squamous cell carcinoma 24 | 129
Carcinoma, Squamous Cell 23 | 110
Neoplasm Invasiveness 23 | 161
Unipolar Depression 23 | 250
nasopharyngeal carcinoma 23 | 1,058
juvenile dermatomyositis 22 | 1,187

Tissue

Blood and immune system 173 | 16,909
Digestive Tract 172 | 17,369
Endocrine System 172 | 18,159
Female tissues 171 | 17,400
Male tissues 171 | 17,142
Skin and soft tissues 171 | 17,230
Liver and Pancreas 170 | 16,750
Respiratory system 169 | 16,393
Urinary Tract 168 | 16,678
Nervous System 165 | 16,725
Cardiovascular System 164 | 15,192

Target Family

Non-IDG 95 | 12,091
Enzyme 36 | 4,145
Kinase 23 | 634
Transcription Factor 19 | 1,400
Nuclear Receptor 5 | 48
Epigenetic 1 | 242
Transporter 1 | 473

Compartment GO Term

BCL-2 complex 180 | 180
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phorbol-12-myristate-13-acetate-induced protein 1 PMAIP1 Tbio Non-IDG -2.70122 462.2 347
Apoptosis-stimulating of p53 protein 2 TP53BP2 Tbio Non-IDG -1.85307 72.5 189
Serpin A9 SERPINA9 Tbio Non-IDG -1.94929 88.4 132
BAG family molecular chaperone regulator 1 BAG1 Tbio Non-IDG -2.50252 335.1 394
Bcl-2-binding component 3 BBC3 Tbio Non-IDG -2.02081 88.0 559
Caspase-2 CASP2 Tchem Enzyme -2.62373 431.8 571
GTPase KRas KRAS Tchem Enzyme -3.80300 6069.9 574
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
Beta-nerve growth factor NGF Tchem Non-IDG -4.01592 10936.7 735
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 CD38 Tclin Enzyme -3.44680 2663.1 1493